Class information for:
Level 1: INTEGRASE//HIV 1 INTEGRASE//LEDGF P75

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2499 2226 47.8 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
29 3       HIV//VIROLOGY//HIV 1 108954
1825 2             INTEGRASE//VPR//APOBEC3G 6199
2499 1                   INTEGRASE//HIV 1 INTEGRASE//LEDGF P75 2226

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTEGRASE authKW 1864213 13% 48% 282
2 HIV 1 INTEGRASE authKW 1615671 7% 79% 150
3 LEDGF P75 authKW 674313 2% 95% 52
4 DIKETO ACIDS authKW 425734 2% 80% 39
5 MOL VIROL GENE THER Y address 349480 3% 44% 58
6 HIV INTEGRASE authKW 340736 2% 59% 42
7 HIV 1 INTEGRASE INHIBITORS authKW 323169 2% 65% 36
8 INTEGRASE INHIBITOR authKW 215075 3% 25% 63
9 HIV INTEGRASE INHIBITORS authKW 210703 1% 59% 26
10 STRAND TRANSFER INHIBITORS authKW 149344 1% 78% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Virology 36705 31% 0% 689
2 Chemistry, Medicinal 7511 18% 0% 393
3 Biochemistry & Molecular Biology 3509 35% 0% 779
4 Chemistry, Organic 641 9% 0% 205
5 Cell Biology 476 9% 0% 210
6 Biophysics 274 5% 0% 114
7 Pharmacology & Pharmacy 238 9% 0% 193
8 Microbiology 103 4% 0% 97
9 Parasitiology 79 1% 0% 33
10 Biochemical Research Methods 64 3% 0% 62

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL VIROL GENE THER Y 349480 3% 44% 58
2 LBPA 111858 2% 20% 41
3 CST MAR ROUKOS 109726 0% 100% 8
4 CANC IMMUNOL AIDS 81197 3% 8% 76
5 PHYSICOCHIM PHARMACOL MACROMOL BIOL 72179 0% 53% 10
6 MOL HUMAN RETROVIROL 72146 0% 48% 11
7 UMR 5097 55028 1% 24% 17
8 UMR 8113 52549 1% 15% 25
9 BIOTECHNOL PHARMACOL GENET PL 50863 1% 23% 16
10 UNITE VIROL MOL VACCINOL 48982 0% 71% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF VIROLOGY 36236 15% 1% 324
2 RETROVIROLOGY 30425 2% 4% 52
3 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 4582 4% 0% 93
4 VIROLOGY 4382 4% 0% 78
5 JOURNAL OF MEDICINAL CHEMISTRY 3876 4% 0% 79
6 BIOORGANIC & MEDICINAL CHEMISTRY 2996 2% 0% 54
7 ADVANCES IN VIRUS RESEARCH 2111 0% 2% 9
8 PLOS PATHOGENS 2053 1% 1% 29
9 VIRUSES-BASEL 1859 1% 1% 15
10 ANTIVIRAL RESEARCH 1251 1% 1% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTEGRASE 1864213 13% 48% 282 Search INTEGRASE Search INTEGRASE
2 HIV 1 INTEGRASE 1615671 7% 79% 150 Search HIV+1+INTEGRASE Search HIV+1+INTEGRASE
3 LEDGF P75 674313 2% 95% 52 Search LEDGF+P75 Search LEDGF+P75
4 DIKETO ACIDS 425734 2% 80% 39 Search DIKETO+ACIDS Search DIKETO+ACIDS
5 HIV INTEGRASE 340736 2% 59% 42 Search HIV+INTEGRASE Search HIV+INTEGRASE
6 HIV 1 INTEGRASE INHIBITORS 323169 2% 65% 36 Search HIV+1+INTEGRASE+INHIBITORS Search HIV+1+INTEGRASE+INHIBITORS
7 INTEGRASE INHIBITOR 215075 3% 25% 63 Search INTEGRASE+INHIBITOR Search INTEGRASE+INHIBITOR
8 HIV INTEGRASE INHIBITORS 210703 1% 59% 26 Search HIV+INTEGRASE+INHIBITORS Search HIV+INTEGRASE+INHIBITORS
9 STRAND TRANSFER INHIBITORS 149344 1% 78% 14 Search STRAND+TRANSFER+INHIBITORS Search STRAND+TRANSFER+INHIBITORS
10 LEDGF 141451 1% 54% 19 Search LEDGF Search LEDGF

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LESBATS, P , ENGELMAN, AN , CHEREPANOV, P , (2016) RETROVIRAL DNA INTEGRATION.CHEMICAL REVIEWS. VOL. 116. ISSUE 20. P. 12730 -12757 253 67% 6
2 DI SANTO, R , (2014) INHIBITING THE HIV INTEGRATION PROCESS: PAST, PRESENT, AND THE FUTURE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 3. P. 539 -566 174 69% 23
3 ZEINALIPOUR-LOIZIDOU, E , NICOLAOU, C , NICOLAIDES, A , KOSTRIKIS, LG , (2007) HIV-1 INTEGRASE: FROM BIOLOGY TO CHEMOTHERAPEUTICS.CURRENT HIV RESEARCH. VOL. 5. ISSUE 4. P. 365 -388 222 73% 16
4 ENGELMAN, A , CHEREPANOV, P , KRISHNAN, L , LI, XA , (2011) STRUCTURAL BIOLOGY OF RETROVIRAL DNA INTEGRATION.VIROLOGY. VOL. 411. ISSUE 2. P. 194 -205 124 89% 46
5 LEWINSKI, MK , BUSHMAN, FD , (2005) RETROVIRAL DNA INTEGRATION - MECHANISM AND CONSEQUENCES.ADVANCES IN GENETICS. VOL. 55. ISSUE . P. 147-181 165 81% 77
6 FENG, L , LARUE, RC , SLAUGHTER, A , KESSL, JJ , KVARATSKHELIA, M , (2015) HIV-1 INTEGRASE MULTIMERIZATION AS A THERAPEUTIC TARGET.FUTURE OF HIV-1 THERAPEUTICS: RESISTANCE IS FUTILE?. VOL. 389. ISSUE . P. 93 -119 110 96% 3
7 DELELIS, O , CARAYON, K , SAIB, A , DEPREZ, E , MOUSCADET, JF , (2008) INTEGRASE AND INTEGRATION: BIOCHEMICAL ACTIVITIES OF HIV-1 INTEGRASE.RETROVIROLOGY. VOL. 5. ISSUE . P. - 117 91% 82
8 LI, X , KOH, Y , ENGELMAN, A , (2012) CORRELATION OF RECOMBINANT INTEGRASE ACTIVITY AND FUNCTIONAL PREINTEGRATION COMPLEX FORMATION DURING ACUTE INFECTION BY REPLICATION-DEFECTIVE INTEGRASE MUTANT HUMAN IMMUNODEFICIENCY VIRUS.JOURNAL OF VIROLOGY. VOL. 86. ISSUE 7. P. 3861-3879 115 92% 7
9 MARCHAND, C , MADDALI, K , METIFIOT, M , POMMIER, Y , (2009) HIV-1 IN INHIBITORS: 2010 UPDATE AND PERSPECTIVES.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 9. ISSUE 11. P. 1016-1037 128 78% 43
10 POESCHLA, EM , (2008) INTEGRASE, LEDGF/P75 AND HIV REPLICATION.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 65. ISSUE 9. P. 1403 -1424 137 71% 68

Classes with closest relation at Level 1


Rank Class id link
1 7021 RALTEGRAVIR//DOLUTEGRAVIR//ETRAVIRINE
2 17572 TY1//SECT EUKARYOT TRANSPOSABLE ELEMENTS//TY ELEMENTS
3 12511 VPR//SAMHD1//VPX
4 31081 HEPATOMA DERIVED GROWTH FACTOR//HDGF//HEPATOMA DERIVED GROWTH FACTOR HDGF
5 3841 VIRUS CELL INTERACT SECT//GAG//HIV DRUG ISTANCE PROGRAM
6 2246 LENTIVIRAL VECTOR//EXPT HEMATOL//RETROVIRAL VECTOR
7 1509 NNRTIS//REVERSE TRANSCRIPTASE//HIV 1 REVERSE TRANSCRIPTASE
8 3643 HIV LATENCY//HIV RESERVOIR//HIV CURE
9 10010 TRIM5 ALPHA//TRIM5//TRIMCYP
10 17295 FOAMY VIRUS//SPUMAVIRUS//SPUMARETROVIRUS

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