Class information for:
Level 1: TRIM5 ALPHA//TRIM5//TRIMCYP

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10010 1099 45.7 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
29 3       HIV//VIROLOGY//HIV 1 108954
1825 2             INTEGRASE//VPR//APOBEC3G 6199
10010 1                   TRIM5 ALPHA//TRIM5//TRIMCYP 1099

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRIM5 ALPHA authKW 1580536 6% 89% 64
2 TRIM5 authKW 565274 2% 88% 23
3 TRIMCYP authKW 444530 1% 100% 16
4 TRIM22 authKW 364961 2% 77% 17
5 RESTRICTION FACTOR authKW 344541 4% 31% 40
6 TRIPARTITE MOTIF authKW 329004 1% 79% 15
7 TRIM21 authKW 308808 2% 65% 17
8 TRIM32 authKW 297668 1% 71% 15
9 TRIM29 authKW 293454 1% 81% 13
10 MID1 authKW 271034 2% 49% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Virology 19767 32% 0% 355
2 Biochemistry & Molecular Biology 1180 30% 0% 328
3 Cell Biology 1084 18% 0% 193
4 Genetics & Heredity 908 13% 0% 144
5 Immunology 526 12% 0% 133
6 Oncology 187 9% 0% 97
7 Biophysics 167 6% 0% 61
8 Parasitiology 124 2% 0% 26
9 Microbiology 91 5% 0% 58
10 Infectious Diseases 76 3% 0% 36

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VIRAL INFECT 119676 3% 14% 31
2 CANC IMMUNOL AIDS AIDS 113442 1% 58% 7
3 AIDS CANC IMMUNOL AIDS 111132 0% 100% 4
4 PROT NUCLE ACID CHEM 105589 2% 18% 21
5 PATHOL AIDS CANC IMMUNOL AIDS 62510 0% 75% 3
6 VIRAL GENOM 59259 1% 27% 8
7 BIOCHEM CANC THER Y 55566 0% 100% 2
8 ONCOL 04 F 14 55566 0% 100% 2
9 DANA FARBER CANC AIDS 50007 0% 60% 3
10 HARVARD PROGRAM VIROL 41672 0% 50% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RETROVIROLOGY 20522 3% 2% 30
2 JOURNAL OF VIROLOGY 13277 13% 0% 138
3 VIROLOGY 3104 4% 0% 46
4 PLOS PATHOGENS 2880 2% 0% 24
5 AMERICAN JOURNAL OF MEDICAL GENETICS 1501 2% 0% 22
6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 717 5% 0% 52
7 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 663 4% 0% 42
8 FISH & SHELLFISH IMMUNOLOGY 612 1% 0% 10
9 AIDS RESEARCH AND HUMAN RETROVIRUSES 609 1% 0% 11
10 VIRUSES-BASEL 600 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRIM5 ALPHA 1580536 6% 89% 64 Search TRIM5+ALPHA Search TRIM5+ALPHA
2 TRIM5 565274 2% 88% 23 Search TRIM5 Search TRIM5
3 TRIMCYP 444530 1% 100% 16 Search TRIMCYP Search TRIMCYP
4 TRIM22 364961 2% 77% 17 Search TRIM22 Search TRIM22
5 RESTRICTION FACTOR 344541 4% 31% 40 Search RESTRICTION+FACTOR Search RESTRICTION+FACTOR
6 TRIPARTITE MOTIF 329004 1% 79% 15 Search TRIPARTITE+MOTIF Search TRIPARTITE+MOTIF
7 TRIM21 308808 2% 65% 17 Search TRIM21 Search TRIM21
8 TRIM32 297668 1% 71% 15 Search TRIM32 Search TRIM32
9 TRIM29 293454 1% 81% 13 Search TRIM29 Search TRIM29
10 MID1 271034 2% 49% 20 Search MID1 Search MID1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NAKAYAMA, EE , SHIODA, T , (2012) ROLE OF HUMAN TRIM5 ALPHA IN INTRINSIC IMMUNITY.FRONTIERS IN MICROBIOLOGY. VOL. 3. ISSUE . P. - 106 82% 8
2 SANZ-RAMOS, M , STOYE, JP , (2013) CAPSID-BINDING RETROVIRUS RESTRICTION FACTORS: DISCOVERY, RESTRICTION SPECIFICITY AND IMPLICATIONS FOR THE DEVELOPMENT OF NOVEL THERAPEUTICS.JOURNAL OF GENERAL VIROLOGY. VOL. 94. ISSUE . P. 2587 -2598 89 74% 15
3 RAJSBAUM, R , GARCIA-SASTRE, A , VERSTEEG, GA , (2014) TRIMMUNITY: THE ROLES OF THE TRIM E3-UBIQUITIN LIGASE FAMILY IN INNATE ANTIVIRAL IMMUNITY.JOURNAL OF MOLECULAR BIOLOGY. VOL. 426. ISSUE 6. P. 1265 -1284 90 57% 41
4 SONG, B , (2009) TRIM5ALPHA.HIV INTERACTIONS WITH HOST CELL PROTEINS. VOL. 339. ISSUE . P. 47 -66 93 77% 13
5 NAKAYAMA, EE , SHIODA, T , (2010) ANTI-RETROVIRAL ACTIVITY OF TRIM5 ALPHA.REVIEWS IN MEDICAL VIROLOGY. VOL. 20. ISSUE 2. P. 77-92 90 70% 40
6 FLETCHER, AJ , TOWERS, GJ , (2013) INHIBITION OF RETROVIRAL REPLICATION BY MEMBERS OF THE TRIM PROTEIN FAMILY.INTRINSIC IMMUNITY. VOL. 371. ISSUE . P. 29-66 111 51% 15
7 KIM, J , TIPPER, C , SODROSKI, J , (2011) ROLE OF TRIM5 ALPHA RING DOMAIN E3 UBIQUITIN LIGASE ACTIVITY IN CAPSID DISASSEMBLY, REVERSE TRANSCRIPTION BLOCKADE, AND RESTRICTION OF SIMIAN IMMUNODEFICIENCY VIRUS.JOURNAL OF VIROLOGY. VOL. 85. ISSUE 16. P. 8116-8132 73 81% 18
8 KAJASTE-RUDNITSKI, A , PULTRONE, C , MARZETTA, F , GHEZZI, S , CORADIN, T , VICENZI, E , (2010) RESTRICTION FACTORS OF RETROVIRAL REPLICATION: THE EXAMPLE OF TRIPARTITE MOTIF (TRIM) PROTEIN 5 ALPHA AND 22.AMINO ACIDS. VOL. 39. ISSUE 1. P. 1 -9 71 80% 8
9 LI, X , KIM, J , SONG, B , FINZI, A , PACHECO, B , SODROSKI, J , (2013) VIRUS-SPECIFIC EFFECTS OF TRIM5 ALPHA(RH) RING DOMAIN FUNCTIONS ON RESTRICTION OF RETROVIRUSES.JOURNAL OF VIROLOGY. VOL. 87. ISSUE 13. P. 7234-7245 55 90% 12
10 NAKAYAMA, EE , SHIODA, T , (2015) IMPACT OF TRIM5 ALPHA IN VIVO.AIDS. VOL. 29. ISSUE 14. P. 1733 -1743 75 68% 0

Classes with closest relation at Level 1


Rank Class id link
1 9090 VIF//APOBEC3G//APOBEC3
2 17542 VPU//TETHERIN//BST 2
3 16854 DAXX//PML//PML NUCLEAR BODIES
4 34066 MULIBREY NANISM//3 M SYNDROME//TRIM37
5 3841 VIRUS CELL INTERACT SECT//GAG//HIV DRUG ISTANCE PROGRAM
6 14264 KRAB DOMAIN//KRAB//SCAN DOMAIN
7 19896 U BOX//RING H2//SAUL1
8 12511 VPR//SAMHD1//VPX
9 2499 INTEGRASE//HIV 1 INTEGRASE//LEDGF P75
10 2033 RIG I//MAVS//MDA5

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