Class information for:
Level 1: PHAGE DISPLAY//SCFV//ANTIBODY LIBRARY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2141 2343 41.1 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
478 3       PHAGE DISPLAY//CELL FREE PROTEIN SYNTHESIS//ANTIBODY ENGINEERING 23687
1834 2             PHAGE DISPLAY//ANTIBODY ENGINEERING//BISPECIFIC ANTIBODY 6173
2141 1                   PHAGE DISPLAY//SCFV//ANTIBODY LIBRARY 2343

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHAGE DISPLAY authKW 1035658 20% 17% 461
2 SCFV authKW 818801 9% 30% 212
3 ANTIBODY LIBRARY authKW 627160 3% 63% 76
4 SINGLE CHAIN FV authKW 552425 5% 40% 107
5 ANTIBODY ENGINEERING authKW 468366 6% 28% 130
6 INTRABODY authKW 446438 3% 49% 70
7 RECOMBINANT ANTIBODY authKW 233380 4% 20% 89
8 PHAGE ANTIBODY authKW 226214 1% 69% 25
9 INTRACELLULAR ANTIBODIES authKW 192436 1% 62% 24
10 SINGLE CHAIN ANTIBODY authKW 169471 3% 21% 63

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemical Research Methods 12254 24% 0% 574
2 Biotechnology & Applied Microbiology 7072 24% 0% 563
3 Biochemistry & Molecular Biology 5433 41% 0% 967
4 Immunology 5053 23% 0% 547
5 Biophysics 553 7% 0% 155
6 Medicine, Research & Experimental 286 5% 0% 124
7 Virology 175 3% 0% 61
8 Cell Biology 168 6% 0% 151
9 Genetics & Heredity 132 5% 0% 108
10 Oncology 100 6% 0% 132

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IG THER Y CO 130308 0% 100% 10
2 ABT BIOTECHNOL 68165 1% 35% 15
3 ANESTHESIA PHARMACEUT CHEM 41681 1% 27% 12
4 RECOMBINANT ANTIBODIES 40717 0% 63% 5
5 BIOTECHNOL ANTICORPS 36079 0% 46% 6
6 RECOMBINANT ANTIBODY GRP 0445 26062 0% 100% 2
7 TUMOR IMMUNOL PROGRAMME MOL IMMUNOL 0740 26062 0% 100% 2
8 WYETH IRELAND 26062 0% 100% 2
9 AD T CLUSTER 23453 0% 60% 3
10 SHANGHAI ADV IMMUNOL STUDIES 23453 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PORTLAND PRESS PROCEEDINGS 138952 1% 33% 32
2 JOURNAL OF IMMUNOLOGICAL METHODS 58939 9% 2% 209
3 PROTEIN ENGINEERING DESIGN & SELECTION 27642 2% 5% 47
4 MABS 19218 1% 4% 33
5 PROTEIN ENGINEERING 13208 2% 2% 48
6 HYBRIDOMA AND HYBRIDOMICS 8964 1% 5% 13
7 JOURNAL OF MOLECULAR BIOLOGY 7380 5% 1% 116
8 BIO-TECHNOLOGY 5642 1% 2% 25
9 BMC BIOTECHNOLOGY 3567 1% 2% 18
10 BIOTECHNIQUES 3547 2% 1% 41

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PHAGE DISPLAY 1035658 20% 17% 461 Search PHAGE+DISPLAY Search PHAGE+DISPLAY
2 SCFV 818801 9% 30% 212 Search SCFV Search SCFV
3 ANTIBODY LIBRARY 627160 3% 63% 76 Search ANTIBODY+LIBRARY Search ANTIBODY+LIBRARY
4 SINGLE CHAIN FV 552425 5% 40% 107 Search SINGLE+CHAIN+FV Search SINGLE+CHAIN+FV
5 ANTIBODY ENGINEERING 468366 6% 28% 130 Search ANTIBODY+ENGINEERING Search ANTIBODY+ENGINEERING
6 INTRABODY 446438 3% 49% 70 Search INTRABODY Search INTRABODY
7 RECOMBINANT ANTIBODY 233380 4% 20% 89 Search RECOMBINANT+ANTIBODY Search RECOMBINANT+ANTIBODY
8 PHAGE ANTIBODY 226214 1% 69% 25 Search PHAGE+ANTIBODY Search PHAGE+ANTIBODY
9 INTRACELLULAR ANTIBODIES 192436 1% 62% 24 Search INTRACELLULAR+ANTIBODIES Search INTRACELLULAR+ANTIBODIES
10 SINGLE CHAIN ANTIBODY 169471 3% 21% 63 Search SINGLE+CHAIN+ANTIBODY Search SINGLE+CHAIN+ANTIBODY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HOOGENBOOM, HR , (2005) SELECTING AND SCREENING RECOMBINANT ANTIBODY LIBRARIES.NATURE BIOTECHNOLOGY. VOL. 23. ISSUE 9. P. 1105-1116 91 58% 502
2 BRADBURY, ARM , MARKS, JD , (2004) ANTIBODIES FROM PHAGE ANTIBODY LIBRARIES.JOURNAL OF IMMUNOLOGICAL METHODS. VOL. 290. ISSUE 1-2. P. 29-49 94 69% 162
3 AHMAD, ZA , YEAP, SK , ALI, AM , HO, WY , ALITHEEN, NBM , HAMID, M , (2012) SCFV ANTIBODY: PRINCIPLES AND CLINICAL APPLICATION.CLINICAL & DEVELOPMENTAL IMMUNOLOGY. VOL. . ISSUE . P. - 86 58% 62
4 JARA-ACEVEDO, R , DIEZ, P , GONZALEZ-GONZALEZ, M , DEGANO, RM , IBARROLA, N , GONGORA, R , ORFAO, A , FUENTES, M , (2016) METHODS FOR SELECTING PHAGE DISPLAY ANTIBODY LIBRARIES.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 43. P. 6490 -6499 67 74% 1
5 HOOGENBOOM, HR , DE BRUINE, AP , HUFTON, SE , HOET, RM , ARENDS, JW , ROOVERS, RC , (1998) ANTIBODY PHAGE DISPLAY TECHNOLOGY AND ITS APPLICATIONS.IMMUNOTECHNOLOGY. VOL. 4. ISSUE 1. P. 1 -20 88 65% 306
6 MIERSCH, S , SIDHU, SS , (2012) SYNTHETIC ANTIBODIES: CONCEPTS, POTENTIAL AND PRACTICAL CONSIDERATIONS.METHODS. VOL. 57. ISSUE 4. P. 486-498 91 49% 36
7 ZHAO, AZ , TOHIDKIA, MR , SIEGEL, DL , COUKOS, G , OMIDI, Y , (2016) PHAGE ANTIBODY DISPLAY LIBRARIES: A POWERFUL ANTIBODY DISCOVERY PLATFORM FOR IMMUNOTHERAPY.CRITICAL REVIEWS IN BIOTECHNOLOGY. VOL. 36. ISSUE 2. P. 276 -289 48 68% 5
8 BRADBURY, ARM , SIDHU, S , DUBEL, S , MCCAFFERTY, J , (2011) BEYOND NATURAL ANTIBODIES: THE POWER OF IN VITRO DISPLAY TECHNOLOGIES.NATURE BIOTECHNOLOGY. VOL. 29. ISSUE 3. P. 245-254 73 44% 162
9 DE HAARD, H , HENDERIKX, P , HOOGENBOOM, HR , (1998) CREATING AND ENGINEERING HUMAN ANTIBODIES FOR IMMUNOTHERAPY.ADVANCED DRUG DELIVERY REVIEWS. VOL. 31. ISSUE 1-2. P. 5 -31 107 60% 23
10 INBAR, NH , BENHAR, I , (2012) SELECTION OF ANTIBODIES FROM SYNTHETIC ANTIBODY LIBRARIES.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 526. ISSUE 2. P. 87 -98 70 58% 9

Classes with closest relation at Level 1


Rank Class id link
1 14481 NANOBODY//SINGLE DOMAIN ANTIBODY//VHH
2 8251 CANONICAL STRUCTURES//ANTIBODY MODELING//HUMANIZATION
3 10551 PHAGE DISPLAY//MIMOTOPE//RANDOM PEPTIDE LIBRARY
4 9947 BISPECIFIC ANTIBODY//BISPECIFIC ANTIBODIES//CATUMAXOMAB
5 17023 CELL SURFACE DISPLAY//SURFACE DISPLAY//CELL SURFACE ENGINEERING
6 14625 RIBOSOME DISPLAY//MRNA DISPLAY//FOUR BASE CODON
7 18905 REPEAT PROTEIN//FN3//ANKYRIN REPEAT
8 37475 ANTIBODY VARIABLE REGION//TRANSGENE SELECTION//COMMUNICATION DISTANCE
9 37049 AD HOC UBIQUITOUS ENVIRONMENT//ANTIBODY FRAGMENT ENGINEERING//BIOSYST AITRC
10 24364 BETA D GALACTOSIDASE//NONCOMPETITIVE IMMUNOASSAY//GELATIN PARTICLE AGGLUTINATION

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