Class information for:
Level 1: BISPECIFIC ANTIBODY//BISPECIFIC ANTIBODIES//CATUMAXOMAB

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9947 1105 40.6 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
478 3       PHAGE DISPLAY//CELL FREE PROTEIN SYNTHESIS//ANTIBODY ENGINEERING 23687
1834 2             PHAGE DISPLAY//ANTIBODY ENGINEERING//BISPECIFIC ANTIBODY 6173
9947 1                   BISPECIFIC ANTIBODY//BISPECIFIC ANTIBODIES//CATUMAXOMAB 1105

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BISPECIFIC ANTIBODY authKW 2702101 16% 54% 181
2 BISPECIFIC ANTIBODIES authKW 1202068 8% 49% 88
3 CATUMAXOMAB authKW 590006 3% 65% 33
4 TRIFUNCTIONAL ANTIBODY authKW 495325 2% 81% 22
5 BISPECIFIC authKW 449864 3% 48% 34
6 BISPECIFIC MONOCLONAL ANTIBODY authKW 317748 2% 50% 23
7 BISPECIFIC DIABODY authKW 233483 1% 65% 13
8 QUADROMA authKW 186513 1% 75% 9
9 BI SPECIFIC ANTIBODY authKW 142107 1% 86% 6
10 CLIN COOPERAT GRP BISPECIF ANTIBODIES address 138161 0% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 5473 37% 0% 409
2 Immunology 5169 33% 0% 369
3 Medicine, Research & Experimental 1257 13% 0% 149
4 Biochemical Research Methods 556 8% 0% 92
5 Hematology 446 7% 0% 76
6 Biotechnology & Applied Microbiology 401 9% 0% 104
7 Biochemistry & Molecular Biology 178 15% 0% 165
8 Pharmacology & Pharmacy 48 7% 0% 73
9 Cell Biology 19 4% 0% 48
10 Transplantation 9 1% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN COOPERAT GRP BISPECIF ANTIBODIES 138161 0% 100% 5
2 ADELE R DECOF CANC 99471 1% 60% 6
3 CELL OURCE BIOMED 83300 1% 22% 14
4 LARGE MOL 67422 1% 20% 12
5 RECOMBINANT ANTIBODY GRP D0500 62171 0% 75% 3
6 ABDOMINAL VASC TRANSPLANT SURG 45208 1% 27% 6
7 IMMUNOTHER Y TREATMENT 31083 0% 38% 3
8 CLIN COOPERAT GRP IMMUNOTHER Y 29469 0% 27% 4
9 MED CLIN POLYCLIN 1 29248 1% 18% 6
10 ABDOMNEL VASC TRANSPLANT SURG 27632 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MABS 121875 5% 8% 57
2 CANCER IMMUNOLOGY IMMUNOTHERAPY 24414 6% 1% 62
3 JOURNAL OF IMMUNOTHERAPY 8656 2% 1% 23
4 INTERNATIONAL JOURNAL OF CANCER 6651 6% 0% 70
5 PROTEIN ENGINEERING DESIGN & SELECTION 4473 1% 1% 13
6 JOURNAL OF IMMUNOLOGICAL METHODS 4085 3% 0% 38
7 TUMOR TARGETING 3808 0% 7% 2
8 HYBRIDOMA 3342 1% 1% 16
9 JOURNAL OF IMMUNOLOGY 2167 6% 0% 66
10 CURRENT OPINION IN MOLECULAR THERAPEUTICS 2010 1% 1% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BISPECIFIC ANTIBODY 2702101 16% 54% 181 Search BISPECIFIC+ANTIBODY Search BISPECIFIC+ANTIBODY
2 BISPECIFIC ANTIBODIES 1202068 8% 49% 88 Search BISPECIFIC+ANTIBODIES Search BISPECIFIC+ANTIBODIES
3 CATUMAXOMAB 590006 3% 65% 33 Search CATUMAXOMAB Search CATUMAXOMAB
4 TRIFUNCTIONAL ANTIBODY 495325 2% 81% 22 Search TRIFUNCTIONAL+ANTIBODY Search TRIFUNCTIONAL+ANTIBODY
5 BISPECIFIC 449864 3% 48% 34 Search BISPECIFIC Search BISPECIFIC
6 BISPECIFIC MONOCLONAL ANTIBODY 317748 2% 50% 23 Search BISPECIFIC+MONOCLONAL+ANTIBODY Search BISPECIFIC+MONOCLONAL+ANTIBODY
7 BISPECIFIC DIABODY 233483 1% 65% 13 Search BISPECIFIC+DIABODY Search BISPECIFIC+DIABODY
8 QUADROMA 186513 1% 75% 9 Search QUADROMA Search QUADROMA
9 BI SPECIFIC ANTIBODY 142107 1% 86% 6 Search BI+SPECIFIC+ANTIBODY Search BI+SPECIFIC+ANTIBODY
10 HYBRID HYBRIDOMA 123084 1% 64% 7 Search HYBRID+HYBRIDOMA Search HYBRID+HYBRIDOMA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BRINKMANN, U , KONTERMANN, RE , (2017) THE MAKING OF BISPECIFIC ANTIBODIES.MABS. VOL. 9. ISSUE 2. P. 182 -212 148 55% 0
2 KONTERMANN, RE , BRINKMANN, U , (2015) BISPECIFIC ANTIBODIES.DRUG DISCOVERY TODAY. VOL. 20. ISSUE 7. P. 838 -847 52 69% 54
3 SPIESS, C , ZHAI, QT , CARTER, PJ , (2015) ALTERNATIVE MOLECULAR FORMATS AND THERAPEUTIC APPLICATIONS FOR BISPECIFIC ANTIBODIES.MOLECULAR IMMUNOLOGY. VOL. 67. ISSUE 2. P. 95 -106 59 53% 55
4 LUM, LG , THAKUR, A , (2011) TARGETING T CELLS WITH BISPECIFIC ANTIBODIES FOR CANCER THERAPY.BIODRUGS. VOL. 25. ISSUE 6. P. 365-379 74 59% 9
5 CHEN, SQ , LI, J , LI, Q , WANG, Z , (2016) BISPECIFIC ANTIBODIES IN CANCER IMMUNOTHERAPY.HUMAN VACCINES & IMMUNOTHERAPEUTICS. VOL. 12. ISSUE 10. P. 2491 -2500 59 61% 1
6 CHAMES, P , BATY, D , (2009) BISPECIFIC ANTIBODIES FOR CANCER THERAPY THE LIGHT AT THE END OF THE TUNNEL?.MABS. VOL. 1. ISSUE 6. P. 539-547 46 79% 97
7 BYRNE, H , CONROY, PJ , WHISSTOCK, JC , O'KENNEDY, RJ , (2013) A TALE OF TWO SPECIFICITIES: BISPECIFIC ANTIBODIES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS.TRENDS IN BIOTECHNOLOGY. VOL. 31. ISSUE 11. P. 621-632 62 49% 62
8 LUM, LG , AL-KADHIMI, Z , (2008) DEVELOPMENT AND PROSPECTS FOR BISPECIFIC ANTIBODY-BASED THERAPEUTICS IN CANCER AND OTHER APPLICATIONS.EXPERT OPINION ON DRUG DISCOVERY. VOL. 3. ISSUE 9. P. 1081-1097 75 56% 1
9 CHEN, ZZ , WANG, LP , XU, TS , WANG, QF , KANG, LS , ZHAO, Q , (2016) GENERATION OF BISPECIFIC ANTIBODIES BY FC HETERODIMERIZATION AND THEIR APPLICATION.CURRENT PHARMACEUTICAL BIOTECHNOLOGY. VOL. 17. ISSUE 15. P. 1324 -1332 53 62% 0
10 FOURNIER, P , SCHIRRMACHER, V , (2013) BISPECIFIC ANTIBODIES AND TRISPECIFIC IMMUNOCYTOKINES FOR TARGETING THE IMMUNE SYSTEM AGAINST CANCER PREPARING FOR THE FUTURE.BIODRUGS. VOL. 27. ISSUE 1. P. 35-53 58 54% 17

Classes with closest relation at Level 1


Rank Class id link
1 12872 EPCAM//TROP2//EP CAM
2 2141 PHAGE DISPLAY//SCFV//ANTIBODY LIBRARY
3 10008 CD20//OFATUMUMAB//OBINUTUZUMAB
4 18119 PRETARGETING//PRETARGETED RADIOIMMUNOTHERAPY//MOL MED IMMUNOL
5 31046 A NK CELLS//T LAK CELLS//ACTIVATED NATURAL KILLER CELLS
6 6520 IMMUNOTOXIN//GELONIN//RICIN A CHAIN
7 14481 NANOBODY//SINGLE DOMAIN ANTIBODY//VHH
8 20644 PERITONEOVENOUS SHUNT//MALIGNANT ASCITES//DENVER SHUNT
9 25493 LEUKEMIA STEM CELLS//LEUKEMIC STEM CELLS//CD123
10 9605 CD2//T11TS//CD58

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