Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
31664 | 149 | 37.6 | 93% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
364 | 3 | TELOMERASE//TELOMERE//C ELEGANS | 34320 |
700 | 2 | TELOMERASE//TELOMERE//TELOMERE LENGTH | 12973 |
31664 | 1 | TANKYRASE//TANKYRASE 1//TANKYRASE INHIBITORS | 149 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | TANKYRASE | authKW | 4618251 | 27% | 56% | 40 |
2 | TANKYRASE 1 | authKW | 1653148 | 7% | 73% | 11 |
3 | TANKYRASE INHIBITORS | authKW | 731913 | 3% | 71% | 5 |
4 | TNKS | authKW | 640423 | 3% | 63% | 5 |
5 | PARSYLATION | authKW | 468423 | 3% | 57% | 4 |
6 | TNKS1 | authKW | 461105 | 2% | 75% | 3 |
7 | TANKYRASE 2 | authKW | 409873 | 1% | 100% | 2 |
8 | BIOASSAY PROFILING | address | 273247 | 1% | 67% | 2 |
9 | UNIT CELL SIGNALING | address | 269646 | 3% | 26% | 5 |
10 | SFI CAST BIOMED INNOVAT | address | 234207 | 3% | 29% | 4 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Chemistry, Medicinal | 757 | 21% | 0% | 32 |
2 | Cell Biology | 402 | 28% | 0% | 41 |
3 | Biochemistry & Molecular Biology | 352 | 42% | 0% | 62 |
4 | Oncology | 116 | 16% | 0% | 24 |
5 | Andrology | 63 | 1% | 0% | 2 |
6 | Biophysics | 46 | 7% | 0% | 11 |
7 | Chemistry, Organic | 10 | 5% | 0% | 8 |
8 | Genetics & Heredity | 9 | 5% | 0% | 7 |
9 | Multidisciplinary Sciences | 6 | 1% | 0% | 2 |
10 | Biochemical Research Methods | 4 | 3% | 0% | 4 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | BIOASSAY PROFILING | 273247 | 1% | 67% | 2 |
2 | UNIT CELL SIGNALING | 269646 | 3% | 26% | 5 |
3 | SFI CAST BIOMED INNOVAT | 234207 | 3% | 29% | 4 |
4 | 07 01 | 204936 | 1% | 100% | 1 |
5 | CHEM BIOMINIST EDUC | 204936 | 1% | 100% | 1 |
6 | CRUK DNA REPAIR ENZYMES GRP | 204936 | 1% | 100% | 1 |
7 | DIRECTORS ROOM | 204936 | 1% | 100% | 1 |
8 | DISCOVERY ONCOL SMALL MOL PHARMA EARLY | 204936 | 1% | 100% | 1 |
9 | EARLY CLIN DRUG DEV GRP | 204936 | 1% | 100% | 1 |
10 | PEDIAT INTERNAL MED MOL BIOL | 204936 | 1% | 100% | 1 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | ACS MEDICINAL CHEMISTRY LETTERS | 3724 | 3% | 0% | 5 |
2 | JOURNAL OF MEDICINAL CHEMISTRY | 1864 | 9% | 0% | 14 |
3 | MOLECULAR BIOSYSTEMS | 678 | 2% | 0% | 3 |
4 | MOLECULAR AND CELLULAR BIOLOGY | 442 | 5% | 0% | 7 |
5 | ONCOLOGY REPORTS | 325 | 3% | 0% | 4 |
6 | ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS | 265 | 1% | 0% | 2 |
7 | BIOCHEMISTRY-MOSCOW | 250 | 2% | 0% | 3 |
8 | BMC BIOLOGY | 242 | 1% | 0% | 1 |
9 | FAMILIAL CANCER | 232 | 1% | 0% | 1 |
10 | AGING-US | 225 | 1% | 0% | 1 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | TANKYRASE | 4618251 | 27% | 56% | 40 | Search TANKYRASE | Search TANKYRASE |
2 | TANKYRASE 1 | 1653148 | 7% | 73% | 11 | Search TANKYRASE+1 | Search TANKYRASE+1 |
3 | TANKYRASE INHIBITORS | 731913 | 3% | 71% | 5 | Search TANKYRASE+INHIBITORS | Search TANKYRASE+INHIBITORS |
4 | TNKS | 640423 | 3% | 63% | 5 | Search TNKS | Search TNKS |
5 | PARSYLATION | 468423 | 3% | 57% | 4 | Search PARSYLATION | Search PARSYLATION |
6 | TNKS1 | 461105 | 2% | 75% | 3 | Search TNKS1 | Search TNKS1 |
7 | TANKYRASE 2 | 409873 | 1% | 100% | 2 | Search TANKYRASE+2 | Search TANKYRASE+2 |
8 | 2 AMINOPYRIDINE OXAZOLIDINONE | 204936 | 1% | 100% | 1 | Search 2+AMINOPYRIDINE+OXAZOLIDINONE | Search 2+AMINOPYRIDINE+OXAZOLIDINONE |
9 | 2 ARYLQUINAZOLIN 4 ONE | 204936 | 1% | 100% | 1 | Search 2+ARYLQUINAZOLIN+4+ONE | Search 2+ARYLQUINAZOLIN+4+ONE |
10 | 7 ARYL 1 METHYL 1 2 3 4 TETRAHYDRO 1 6 NAPHTHYRIDIN 5 ONE | 204936 | 1% | 100% | 1 | Search 7+ARYL+1+METHYL+1+2+3+4+TETRAHYDRO+1+6+NAPHTHYRIDIN+5+ONE | Search 7+ARYL+1+METHYL+1+2+3+4+TETRAHYDRO+1+6+NAPHTHYRIDIN+5+ONE |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | LEHTIO, L , CHI, NW , KRAUSS, S , (2013) TANKYRASES AS DRUG TARGETS.FEBS JOURNAL. VOL. 280. ISSUE 15. P. 3576-3593 | 58 | 61% | 49 |
2 | HAIKARAINEN, T , KRAUSS, S , LEHTIO, L , (2014) TANKYRASES: STRUCTURE, FUNCTION AND THERAPEUTIC IMPLICATIONS IN CANCER.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 41. P. 6472 -6488 | 68 | 40% | 14 |
3 | WAALER, J , IGNATEV, A , NKIZINKIKO, Y , VENKANNAGARI, H , OBAJI, E , KRAUSS, S , LEHTIO, L , HAIKARAINEN, T , (2016) DEVELOPMENT AND STRUCTURAL ANALYSIS OF ADENOSINE SITE BINDING TANKYRASE INHIBITORS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 26. ISSUE 2. P. 328 -333 | 22 | 85% | 0 |
4 | PAINE, HA , NATHUBHAI, A , WOON, ECY , SUNDERLAND, PT , WOOD, PJ , MAHON, MF , LLOYD, MD , THOMPSON, AS , HAIKARAINEN, T , NARWAL, M , ET AL (2015) EXPLORATION OF THE NICOTINAMIDE-BINDING SITE OF THE TANKYRASES, IDENTIFYING 3-ARYLISOQUINOLIN-1-ONES AS POTENT AND SELECTIVE INHIBITORS IN VITRO.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 23. ISSUE 17. P. 5891 -5908 | 33 | 50% | 4 |
5 | ZHAN, P , SONG, YN , ITOH, Y , SUZUKI, T , LIU, XY , (2014) RECENT ADVANCES IN THE STRUCTURE-BASED RATIONAL DESIGN OF TNKSIS.MOLECULAR BIOSYSTEMS. VOL. 10. ISSUE 11. P. 2783 -2799 | 26 | 60% | 3 |
6 | KAMAL, A , RIYAZ, S , SRIVASTAVA, AK , RAHIM, A , (2014) TANKYRASE INHIBITORS AS THERAPEUTIC TARGETS FOR CANCER.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 14. ISSUE 17. P. 1967 -1976 | 25 | 63% | 3 |
7 | NKIZINKIKO, Y , KUMAR, BVSS , JEANKUMAR, VU , HAIKARAINEN, T , KOIVUNEN, J , MADHURI, C , YOGEESWARI, P , VENKANNAGARI, H , OBAJI, E , PIHLAJANIEMI, T , ET AL (2015) DISCOVERY OF POTENT AND SELECTIVE NONPLANAR TANKYRASE INHIBITING NICOTINAMIDE MIMICS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 23. ISSUE 15. P. 4139 -4149 | 24 | 59% | 2 |
8 | HAIKARAINEN, T , NATHUBHAI, A , HAYWARD, PC , MUNOZ-DESCALZO, S , THOMPSON, AS , LLOYD, MD , LEHTIO, L , THREADGILL, MD , (2016) STRUCTURE-ACTIVITY RELATIONSHIPS OF 2-ARYLQUINAZOLIN-4-ONES AS HIGHLY SELECTIVE AND POTENT INHIBITORS OF THE TANKYRASES.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 118. ISSUE . P. 316 -327 | 27 | 47% | 0 |
9 | HAIKARAINEN, T , KOIVUNEN, J , NARWAL, M , VENKANNAGARI, H , OBAJI, E , JOENSUU, P , PIHLAJANIEMI, T , LEHTIO, L , (2013) PARA-SUBSTITUTED 2-PHENYL-3,4-DIHYDROQUINAZOLIN-4-ONES AS POTENT AND SELECTIVE TANKYRASE INHIBITORS.CHEMMEDCHEM. VOL. 8. ISSUE 12. P. 1978-1985 | 20 | 61% | 8 |
10 | MARIOTTI, L , TEMPLETON, CM , RANES, M , PARACUELLOS, P , CRONIN, N , BEURON, F , MORRIS, E , GUETTLER, S , (2016) TANKYRASE REQUIRES SAM DOMAIN-DEPENDENT POLYMERIZATION TO SUPPORT WNT-BETA-CATENIN SIGNALING.MOLECULAR CELL. VOL. 63. ISSUE 3. P. 498 -513 | 26 | 39% | 2 |
Classes with closest relation at Level 1 |