Class information for:
Level 1: EPOXYEICOSATRIENOIC ACIDS//SOLUBLE EPOXIDE HYDROLASE//20 HYDROXYEICOSATETRAENOIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2000 2392 44.9 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
566 2             EPOXYEICOSATRIENOIC ACIDS//LIPOXYGENASE//LEUKOTRIENES 14430
2000 1                   EPOXYEICOSATRIENOIC ACIDS//SOLUBLE EPOXIDE HYDROLASE//20 HYDROXYEICOSATETRAENOIC ACID 2392

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPOXYEICOSATRIENOIC ACIDS authKW 3047284 13% 79% 302
2 SOLUBLE EPOXIDE HYDROLASE authKW 2416206 9% 86% 221
3 20 HYDROXYEICOSATETRAENOIC ACID authKW 1029301 4% 81% 100
4 20 HETE authKW 964150 4% 79% 96
5 EETS authKW 540824 2% 85% 50
6 DIHYDROXYEICOSATRIENOIC ACID authKW 408442 1% 100% 32
7 CYP2J2 authKW 388290 2% 82% 37
8 EPOXYGENASE authKW 310923 2% 59% 41
9 SEH authKW 300149 1% 87% 27
10 SOLUBLE EPOXIDE HYDROLASE INHIBITOR authKW 259689 1% 88% 23

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 5501 15% 0% 349
2 Physiology 3890 15% 0% 349
3 Biochemistry & Molecular Biology 3116 32% 0% 773
4 Pharmacology & Pharmacy 2433 20% 0% 490
5 Biophysics 990 8% 0% 200
6 Cardiac & Cardiovascular System 964 9% 0% 217
7 Cell Biology 755 11% 0% 262
8 Chemistry, Medicinal 368 4% 0% 106
9 Urology & Nephrology 315 4% 0% 98
10 Endocrinology & Metabolism 237 5% 0% 122

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UCD CANC 131417 1% 47% 22
2 UC DAVIS COMPREHENS CANC 112295 1% 40% 22
3 VASC SIGNALLING GRP 106352 1% 56% 15
4 INTRAMURAL 102450 4% 8% 104
5 SW MED MOLEC GENET 88294 1% 43% 16
6 UCD COMPREHENS CANC 70026 1% 37% 15
7 ENTOMOL CANC 69489 0% 78% 7
8 VASC SIGNALLING 55112 1% 24% 18
9 PULM PATHOBIOL 51167 1% 21% 19
10 KARDIOVASK PHYSIOL 48510 1% 22% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROSTAGLANDINS & OTHER LIPID MEDIATORS 58450 4% 5% 91
2 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 8481 1% 3% 23
3 HYPERTENSION 8303 4% 1% 87
4 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 7317 4% 1% 85
5 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 5388 2% 1% 53
6 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 4458 3% 0% 78
7 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 3574 3% 0% 78
8 DRUG METABOLISM AND DISPOSITION 2266 2% 0% 37
9 JOURNAL OF LIPID RESEARCH 2216 2% 0% 39
10 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 1951 2% 0% 37

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EPOXYEICOSATRIENOIC ACIDS 3047284 13% 79% 302 Search EPOXYEICOSATRIENOIC+ACIDS Search EPOXYEICOSATRIENOIC+ACIDS
2 SOLUBLE EPOXIDE HYDROLASE 2416206 9% 86% 221 Search SOLUBLE+EPOXIDE+HYDROLASE Search SOLUBLE+EPOXIDE+HYDROLASE
3 20 HYDROXYEICOSATETRAENOIC ACID 1029301 4% 81% 100 Search 20+HYDROXYEICOSATETRAENOIC+ACID Search 20+HYDROXYEICOSATETRAENOIC+ACID
4 20 HETE 964150 4% 79% 96 Search 20+HETE Search 20+HETE
5 EETS 540824 2% 85% 50 Search EETS Search EETS
6 DIHYDROXYEICOSATRIENOIC ACID 408442 1% 100% 32 Search DIHYDROXYEICOSATRIENOIC+ACID Search DIHYDROXYEICOSATRIENOIC+ACID
7 CYP2J2 388290 2% 82% 37 Search CYP2J2 Search CYP2J2
8 EPOXYGENASE 310923 2% 59% 41 Search EPOXYGENASE Search EPOXYGENASE
9 SEH 300149 1% 87% 27 Search SEH Search SEH
10 SOLUBLE EPOXIDE HYDROLASE INHIBITOR 259689 1% 88% 23 Search SOLUBLE+EPOXIDE+HYDROLASE+INHIBITOR Search SOLUBLE+EPOXIDE+HYDROLASE+INHIBITOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 IMIG, JD , (2012) EPOXIDES AND SOLUBLE EPOXIDE HYDROLASE IN CARDIOVASCULAR PHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 92. ISSUE 1. P. 101-130 273 84% 114
2 ROMAN, RJ , (2002) P-450 METABOLITES OF ARACHIDONIC ACID IN THE CONTROL OF CARDIOVASCULAR FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 82. ISSUE 1. P. 131 -185 286 60% 792
3 WESTPHAL, C , KONKEL, A , SCHUNCK, WH , (2015) CYTOCHROME P450 ENZYMES IN THE BIOACTIVATION OF POLYUNSATURATED FATTY ACIDS AND THEIR ROLE IN CARDIOVASCULAR DISEASE.MONOOXYGENASE, PEROXIDASE AND PEROXYGENASE PROPERTIES AND MECHANISMS OF CYTOCHROME P450. VOL. 851. ISSUE . P. 151 -187 227 82% 4
4 SPECTOR, AA , KIM, HY , (2015) CYTOCHROME P-450 EPOXYGENASE PATHWAY OF POLYUNSATURATED FATTY ACID METABOLISM.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1851. ISSUE 4. P. 356 -365 146 92% 16
5 FLEMING, I , (2014) THE PHARMACOLOGY OF THE CYTOCHROME P450 EPOXYGENASE/SOLUBLE EPOXIDE HYDROLASE AXIS IN THE VASCULATURE AND CARDIOVASCULAR DISEASE.PHARMACOLOGICAL REVIEWS. VOL. 66. ISSUE 4. P. 1106 -1140 244 58% 19
6 FAN, F , GE, Y , LV, WS , ELLIOTT, MR , MUROYA, Y , HIRATA, T , BOOZ, GW , ROMAN, RJ , (2016) MOLECULAR MECHANISMS AND CELL SIGNALING OF 20-HYDROXYEICOSATETRAENOIC ACID IN VASCULAR PATHOPHYSIOLOGY.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 21. ISSUE . P. 1427 -1463 226 66% 0
7 MORISSEAU, C , HAMMOCK, BD , (2013) IMPACT OF SOLUBLE EPOXIDE HYDROLASE AND EPOXYEICOSANOIDS ON HUMAN HEALTH.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013. VOL. 53. ISSUE . P. 37-58 116 91% 75
8 IMIG, JD , HAMMOCK, BD , (2009) SOLUBLE EPOXIDE HYDROLASE AS A THERAPEUTIC TARGET FOR CARDIOVASCULAR DISEASES.NATURE REVIEWS DRUG DISCOVERY. VOL. 8. ISSUE 10. P. 794 -805 122 88% 170
9 WU, CC , GUPTA, T , GARCIA, V , DING, Y , SCHWARTZMAN, ML , (2014) 20-HETE AND BLOOD PRESSURE REGULATION CLINICAL IMPLICATIONS.CARDIOLOGY IN REVIEW. VOL. 22. ISSUE 1. P. 1 -12 151 73% 25
10 KONKEL, A , SCHUNCK, WH , (2011) ROLE OF CYTOCHROME P450 ENZYMES IN THE BIOACTIVATION OF POLYUNSATURATED FATTY ACIDS.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1814. ISSUE 1. P. 210-222 153 75% 69

Classes with closest relation at Level 1


Rank Class id link
1 12974 EPOXIDE HYDROLASE//CIS EPOXYSUCCINATE HYDROLASE//GRP BIOCATALYSE CHIM FINE
2 4694 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR//EDHF//ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF
3 24065 5 OXO ETE//HEPOXILIN A3//CLAUDE PEPPER
4 21584 13 OXOOCTADECADIENOIC ACID//13 HODE//HYDROXY OCTADECADIENOIC ACID
5 22160 5 METHOXYTRYPTAMINE O DEMETHYLATION//BRAIN CYPS//BRAIN DRUG METABOLISM
6 12400 MED BIOCHEM KURAMOTO CHO//PHARMACEUT S KITA KU//IMMUNOADSORPTION COLUMN
7 27533 PHARMACOKINET BIOANAL//HUMANIZED LIVER//PL DEV BIOL
8 3761 PEROXISOME PROLIFERATOR//PEROXISOME PROLIFERATION//3 THIA FATTY ACIDS
9 1927 CYTOCHROME P450//S BIOCHEM//ONE DAY TREATMENT
10 27806 EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE//PROSTACYCLIN SYNTHASE GENE

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