Class information for:
Level 1: EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE//PROSTACYCLIN SYNTHASE GENE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
27806 220 32.3 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
1311 2             PROSTAGLANDIN D 2//CRTH2//MOL BEHAV BIOL 8520
27806 1                   EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE//PROSTACYCLIN SYNTHASE GENE 220

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPT THER EUT PHARMACOINFORMAT address 730183 5% 48% 11
2 PROSTACYCLIN SYNTHASE authKW 703702 8% 30% 17
3 PROSTACYCLIN SYNTHASE GENE authKW 578320 2% 83% 5
4 CYP5A1 authKW 416392 1% 100% 3
5 THROMBOXANE SYNTHASE authKW 386192 7% 17% 16
6 BIOTECHNOL MED BIOTECHNOL address 317247 2% 57% 4
7 12 S HYDROXYHEPTADECATRIENOIC ACID HHT authKW 277594 1% 100% 2
8 PROSTAGLANDIN 12 authKW 277594 1% 100% 2
9 PROSTAGLANDIN E 2 SYNTHASE PGES authKW 277594 1% 100% 2
10 WAFIC SAID MOL CARDIOL address 277594 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1032 56% 0% 124
2 Biophysics 601 20% 0% 43
3 Cell Biology 150 15% 0% 33
4 Peripheral Vascular Diseases 96 7% 0% 15
5 Endocrinology & Metabolism 47 7% 0% 15
6 Genetics & Heredity 31 6% 0% 14
7 Cardiac & Cardiovascular System 15 5% 0% 10
8 Medicine, Research & Experimental 13 4% 0% 9
9 Pharmacology & Pharmacy 8 6% 0% 14
10 Biotechnology & Applied Microbiology 8 4% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPT THER EUT PHARMACOINFORMAT 730183 5% 48% 11
2 BIOTECHNOL MED BIOTECHNOL 317247 2% 57% 4
3 WAFIC SAID MOL CARDIOL 277594 1% 100% 2
4 NAT PL SCI BIOL BOX 306 185062 1% 67% 2
5 CHEM PHYSIOLOGICALLY ACT AGENTS 138797 0% 100% 1
6 INVEST CLIN CH U 138797 0% 100% 1
7 KLIN POLIKLIN FRAUENHEIKUNDE GEBURTSHILFE 138797 0% 100% 1
8 MATH NATURWISSEN AFTLICHE SEKT 138797 0% 100% 1
9 MED GENET ASTHMA OTHER COMPLEX DIS 138797 0% 100% 1
10 MED HUMAN GENET OBSTET GYNECOL 138797 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 11200 4% 1% 8
2 EICOSANOIDS 4547 1% 2% 2
3 MUTATION RESEARCH-GENOMICS 3557 0% 3% 1
4 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 2078 7% 0% 16
5 PROSTAGLANDINS & OTHER LIPID MEDIATORS 1915 2% 0% 5
6 BULLETIN OF MOLECULAR BIOLOGY AND MEDICINE 1026 0% 1% 1
7 BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY 760 1% 0% 2
8 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 706 2% 0% 4
9 VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY 518 0% 0% 1
10 GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING 514 0% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROSTACYCLIN SYNTHASE 703702 8% 30% 17 Search PROSTACYCLIN+SYNTHASE Search PROSTACYCLIN+SYNTHASE
2 PROSTACYCLIN SYNTHASE GENE 578320 2% 83% 5 Search PROSTACYCLIN+SYNTHASE+GENE Search PROSTACYCLIN+SYNTHASE+GENE
3 CYP5A1 416392 1% 100% 3 Search CYP5A1 Search CYP5A1
4 THROMBOXANE SYNTHASE 386192 7% 17% 16 Search THROMBOXANE+SYNTHASE Search THROMBOXANE+SYNTHASE
5 12 S HYDROXYHEPTADECATRIENOIC ACID HHT 277594 1% 100% 2 Search 12+S+HYDROXYHEPTADECATRIENOIC+ACID+HHT Search 12+S+HYDROXYHEPTADECATRIENOIC+ACID+HHT
6 PROSTAGLANDIN 12 277594 1% 100% 2 Search PROSTAGLANDIN+12 Search PROSTAGLANDIN+12
7 PROSTAGLANDIN E 2 SYNTHASE PGES 277594 1% 100% 2 Search PROSTAGLANDIN+E+2+SYNTHASE+PGES Search PROSTAGLANDIN+E+2+SYNTHASE+PGES
8 PROSTAGLANDIN I 2 SYNTHASE 208193 1% 50% 3 Search PROSTAGLANDIN+I+2+SYNTHASE Search PROSTAGLANDIN+I+2+SYNTHASE
9 12 S HYDROXYHEPTADECATRIENOIC ACID 138797 0% 100% 1 Search 12+S+HYDROXYHEPTADECATRIENOIC+ACID Search 12+S+HYDROXYHEPTADECATRIENOIC+ACID
10 ANOMERS EQUILIBRIUM 138797 0% 100% 1 Search ANOMERS+EQUILIBRIUM Search ANOMERS+EQUILIBRIUM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RUAN, KH , (2004) ADVANCE IN UNDERSTANDING THE BIOSYNTHESIS OF PROSTACYCLIN AND THROMBOXANE A(2) IN THE ENDOPLASMIC RETICULUM MEMBRANE VIA THE CYCLOOXYGENASE PATHWAY.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 6. P. 639 -647 24 65% 18
2 WU, KK , LIOU, JY , (2005) CELLULAR AND MOLECULAR BIOLOGY OF PROSTACYCLIN SYNTHASE.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 338. ISSUE 1. P. 45-52 26 51% 46
3 TANABE, T , ULLRICH, V , (1995) PROSTACYCLIN AND THROMBOXANE SYNTHASES.JOURNAL OF LIPID MEDIATORS AND CELL SIGNALLING. VOL. 12. ISSUE 2-3. P. 243-255 25 58% 48
4 WADA, M , YOKOYAMA, C , HATAE, T , SHIMONISHI, M , NAKAMURA, M , IMAI, Y , ULLRICH, V , TANABE, T , (2004) PURIFICATION AND CHARACTERIZATION OF RECOMBINANT HUMAN PROSTACYCLIN SYNTHASE.JOURNAL OF BIOCHEMISTRY. VOL. 135. ISSUE 4. P. 455 -463 19 56% 14
5 CHO, SA , ROHN-GLOWACKI, KJ , JAFFAR, YB , YI, M , KIM, WY , SHIN, JG , LEE, SJ , (2015) ANALYSIS OF GENETIC POLYMORPHISM AND BIOCHEMICAL CHARACTERIZATION OF A FUNCTIONALLY DECREASED VARIANT IN PROSTACYCLIN SYNTHASE GENE (CYP8A1) IN HUMANS.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 569. ISSUE . P. 10 -18 16 50% 1
6 WANG, LH , KULMACZ, RJ , (2002) THROMBOXANE SYNTHASE: STRUCTURE AND FUNCTION OF PROTEIN AND GENE.PROSTAGLANDINS & OTHER LIPID MEDIATORS. VOL. 68-9. ISSUE . P. 409 -422 23 42% 18
7 NAKAYAMA, T , (2010) GENETIC POLYMORPHISMS OF PROSTACYCLIN SYNTHASE GENE AND CARDIOVASCULAR DISEASE.INTERNATIONAL ANGIOLOGY. VOL. 29. ISSUE 2. P. 33-42 18 41% 8
8 CHEVALIER, D , LO-GUIDICE, JM , SERGENT, E , ALLORGE, D , DEBUYSERE, H , FERRARI, N , LIBERSA, C , LHERMITTE, M , BROLY, F , (2001) IDENTIFICATION OF GENETIC VARIANTS IN THE HUMAN THROMBOXANE SYNTHASE GENE (CYP5A1).MUTATION RESEARCH-GENOMICS. VOL. 432. ISSUE 3-4. P. 61 -67 14 61% 15
9 RUAN, KH , DENG, H , WU, HX , SO, SP , (2005) THE N-TERMINAL MEMBRANE ANCHOR DOMAIN OF THE MEMBRANE-BOUND PROSTACYCLIN SYNTHASE INVOLVED IN THE SUBSTRATE PRESENTATION OF THE COUPLING REACTION WITH CYCLOOXYGENASE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 435. ISSUE 2. P. 372-381 13 54% 12
10 RUAN, KH , WU, JX , CERVANTES, V , (2008) CHARACTERIZATION OF THE SUBSTRATE MIMIC BOUND TO ENGINEERED PROSTACYCLIN SYNTHASE IN SOLUTION USING HIGH-RESOLUTION NMR SPECTROSCOPY AND MUTAGENESIS: IMPLICATION OF THE MOLECULAR MECHANISM IN BIOSYNTHESIS OF PROSTACYCLIN.BIOCHEMISTRY. VOL. 47. ISSUE 2. P. 680-688 13 50% 1

Classes with closest relation at Level 1


Rank Class id link
1 3898 THROMBOXANE A2 RECEPTOR//THROMBOXANE A2//THROMBOXANE RECEPTOR
2 19756 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 1 INHIBITORS
3 2243 CYCLOOXYGENASE//PROSTAGLANDIN H SYNTHASE//AB HANCOCK JR MEM CANC
4 25991 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE//15 PGDH//15 HYDROXYPROSTAGLANDIN DEHYDROGENASE 15 PGDH
5 5984 PROSTANOID RECEPTORS//EP3 RECEPTOR//IP RECEPTOR
6 20597 PROSTACYCLIN STIMULATING FACTOR//1 3 7 TRIMETHYLURIC ACID ANALOGUES//1 3 CYCLIC DIKETONE
7 19004 AGGREGATED PROTEIN//FRANCE HELLEN BIOMED//N 6 N 3 POLYUNSATURATED FATTY ACIDS
8 12400 MED BIOCHEM KURAMOTO CHO//PHARMACEUT S KITA KU//IMMUNOADSORPTION COLUMN
9 26627 ASPIRIN LIKE DEFECT OF PLATELETS//BIOSTAT EXPERT KONYA//CERVICAL JOINTS
10 37489 CA 2 SPIKING//DAMAGED AORTA//LAW INTERDISCIPLINE

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