Class information for:
Level 1: ARTIFICIAL METALLOENZYMES//BIOHYBRID CATALYSIS//CHEMOGENETIC OPTIMIZATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19390 507 48.3 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
239 3       LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS 47598
2423 2             CATALYTIC ANTIBODIES//ABZYME//DIRECTED EVOLUTION 4132
19390 1                   ARTIFICIAL METALLOENZYMES//BIOHYBRID CATALYSIS//CHEMOGENETIC OPTIMIZATION 507

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARTIFICIAL METALLOENZYMES authKW 2024799 8% 82% 41
2 BIOHYBRID CATALYSIS authKW 240906 1% 100% 4
3 CHEMOGENETIC OPTIMIZATION authKW 240906 1% 100% 4
4 SHANGHAI CHEM BIOL PROT address 188204 1% 63% 5
5 METALLOENZYMES authKW 163369 7% 8% 34
6 PROT STRUCT FUNCT address 159398 3% 18% 15
7 SEMISYNTHETIC ENZYME authKW 137657 1% 57% 4
8 HYBRID BIOCATALYST authKW 135508 1% 75% 3
9 DNA BASED HYBRID CATALYST authKW 120453 0% 100% 2
10 MOL CHEM MAT address 120453 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Multidisciplinary 2949 49% 0% 249
2 Chemistry, Organic 1003 21% 0% 107
3 Chemistry, Inorganic & Nuclear 619 13% 0% 67
4 Chemistry, Medicinal 223 7% 0% 35
5 Biochemistry & Molecular Biology 86 15% 0% 77
6 Biophysics 35 4% 0% 21
7 Chemistry, Physical 30 8% 0% 43
8 Biochemical Research Methods 11 3% 0% 13
9 Crystallography 8 2% 0% 9
10 Chemistry, Applied 8 2% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SHANGHAI CHEM BIOL PROT 188204 1% 63% 5
2 PROT STRUCT FUNCT 159398 3% 18% 15
3 MOL CHEM MAT 120453 0% 100% 2
4 STRATINGH CHEM 97536 7% 5% 33
5 BIOCHEM ANORGAN CHEM 86786 1% 21% 7
6 ARTERIOSCLEROL HUMAN PROV 60226 0% 100% 1
7 BIJVOET BIOMOL MEMBRANE ENZYMOL 60226 0% 100% 1
8 BIO ELECT GRP 1 60226 0% 100% 1
9 BIOL STRUCT JEAN PIERRE EBELGRP METALLOPRO 60226 0% 100% 1
10 BIOZENBTRUM 60226 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMCATCHEM 3945 3% 1% 13
2 CHEMBIOCHEM 3893 3% 0% 17
3 CURRENT OPINION IN CHEMICAL BIOLOGY 3861 2% 1% 11
4 ACS CATALYSIS 3475 3% 0% 14
5 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 3398 9% 0% 47
6 CHEMISTRYOPEN 2154 1% 1% 3
7 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 1646 10% 0% 51
8 CHEMICAL COMMUNICATIONS 1594 7% 0% 34
9 CHEMICAL SCIENCE 1539 2% 0% 10
10 PROGRESS IN INORGANIC CHEMISTRY 1257 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ARTIFICIAL METALLOENZYMES 2024799 8% 82% 41 Search ARTIFICIAL+METALLOENZYMES Search ARTIFICIAL+METALLOENZYMES
2 BIOHYBRID CATALYSIS 240906 1% 100% 4 Search BIOHYBRID+CATALYSIS Search BIOHYBRID+CATALYSIS
3 CHEMOGENETIC OPTIMIZATION 240906 1% 100% 4 Search CHEMOGENETIC+OPTIMIZATION Search CHEMOGENETIC+OPTIMIZATION
4 METALLOENZYMES 163369 7% 8% 34 Search METALLOENZYMES Search METALLOENZYMES
5 SEMISYNTHETIC ENZYME 137657 1% 57% 4 Search SEMISYNTHETIC+ENZYME Search SEMISYNTHETIC+ENZYME
6 HYBRID BIOCATALYST 135508 1% 75% 3 Search HYBRID+BIOCATALYST Search HYBRID+BIOCATALYST
7 DNA BASED HYBRID CATALYST 120453 0% 100% 2 Search DNA+BASED+HYBRID+CATALYST Search DNA+BASED+HYBRID+CATALYST
8 BIOTIN AVIDIN TECHNOLOGY 120449 1% 50% 4 Search BIOTIN+AVIDIN+TECHNOLOGY Search BIOTIN+AVIDIN+TECHNOLOGY
9 BIOTIN STREPTAVIDIN TECHNOLOGY 90337 1% 50% 3 Search BIOTIN+STREPTAVIDIN+TECHNOLOGY Search BIOTIN+STREPTAVIDIN+TECHNOLOGY
10 PHOSPHINO AMINO ACIDS 90337 1% 50% 3 Search PHOSPHINO+AMINO+ACIDS Search PHOSPHINO+AMINO+ACIDS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PAMIES, O , DIEGUEZ, M , BACKVALL, JE , (2015) ARTIFICIAL METALLOENZYMES IN ASYMMETRIC CATALYSIS: KEY DEVELOPMENTS AND FUTURE DIRECTIONS.ADVANCED SYNTHESIS & CATALYSIS. VOL. 357. ISSUE 8. P. 1567 -1586 74 65% 10
2 BOS, J , ROELFES, G , (2014) ARTIFICIAL METALLOENZYMES FOR ENANTIOSELECTIVE CATALYSIS.CURRENT OPINION IN CHEMICAL BIOLOGY. VOL. 19. ISSUE . P. 135-143 41 87% 41
3 DEUSS, PJ , DEN HEETEN, R , LAAN, W , KAMER, PCJ , (2011) BIOINSPIRED CATALYST DESIGN AND ARTIFICIAL METALLOENZYMES.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 17. ISSUE 17. P. 4680-4698 88 43% 103
4 HOARAU, M , HUREAU, C , GRAS, E , FALLER, P , (2016) COORDINATION COMPLEXES AND BIOMOLECULES: A WISE WEDDING FOR CATALYSIS UPGRADE.COORDINATION CHEMISTRY REVIEWS. VOL. 308. ISSUE . P. 445 -459 59 57% 5
5 LEWIS, JC , (2013) ARTIFICIAL METALLOENZYMES AND METALLOPEPTIDE CATALYSTS FOR ORGANIC SYNTHESIS.ACS CATALYSIS. VOL. 3. ISSUE 12. P. 2954-2975 81 42% 74
6 ROSATI, F , ROELFES, G , (2010) ARTIFICIAL METALLOENZYMES.CHEMCATCHEM. VOL. 2. ISSUE 8. P. 916-927 53 75% 87
7 DRIENOVSKA, I , ROELFES, G , (2015) ARTIFICIAL METALLOENZYMES FOR ASYMMETRIC CATALYSIS BY CREATION OF NOVEL ACTIVE SITES IN PROTEIN AND DNA SCAFFOLDS.ISRAEL JOURNAL OF CHEMISTRY. VOL. 55. ISSUE 1. P. 21 -31 51 78% 2
8 HYSTER, TK , WARD, TR , (2016) GENETIC OPTIMIZATION OF METALLOENZYMES: ENHANCING ENZYMES FOR NON-NATURAL REACTIONS.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 55. ISSUE 26. P. 7344 -7357 48 54% 3
9 PARK, S , OKAMURA, I , SAKASHITA, S , YUM, JH , ACHARYA, C , GAO, L , SUGIYAMA, H , (2015) DEVELOPMENT OF DNA METALLOENZYMES USING A RATIONAL DESIGN APPROACH AND APPLICATION IN THE ASYMMETRIC DIELS-ALDER REACTION.ACS CATALYSIS. VOL. 5. ISSUE 8. P. 4708 -4712 32 80% 7
10 BENEDETTI, E , DUCHEMIN, N , BETHGE, L , VONHOFF, S , KLUSSMANN, S , VASSEUR, JJ , COSSY, J , SMIETANA, M , ARSENIYADIS, S , (2015) DNA-CELLULOSE: AN ECONOMICAL, FULLY RECYCLABLE AND HIGHLY EFFECTIVE CHIRAL BIOMATERIAL FOR ASYMMETRIC CATALYSIS.CHEMICAL COMMUNICATIONS. VOL. 51. ISSUE 28. P. 6076 -6079 27 79% 6

Classes with closest relation at Level 1


Rank Class id link
1 27924 HIGH INTENS XRAY DIFFRACT//ARTIFICIAL SELENOENZYME//BIOELECTRONIS
2 24597 ACTIVITY FINGERPRINT//2D FLUORESEENCE SPECTROSCOPY//ADRENALIN TEST AND COPPER CALCEIN ASSAY FOR AMINO ACIDS
3 5549 COILED COIL//PROTEIN DESIGN//DE NOVO DESIGN
4 18729 OMEGA TRANSAMINASE//CHIRAL AMINES//TRANSAMINASES
5 10945 DIRECTED EVOLUTION//DNA SHUFFLING//RANDOM MUTAGENESIS
6 15869 AVIDIN//STREPTAVIDIN//BIOTIN BINDING PROTEIN
7 8400 CATALYTIC ANTIBODIES//ABZYME//CHEM IMMUNOL THER EUT
8 20803 CHLOROPEROXIDASE//CALDARIOMYCES FUMAGO//PEROXYGENASE
9 13291 COMPUTATIONAL PROTEIN DESIGN//PROTEIN DESIGN//DEAD END ELIMINATION
10 18542 ORGANOMETALL COORDINAT CPDS//PHOSPHORUS MACROCYCLES//1 5 DIAZA 3 7 DIPHOSPHACYCLOOCTANES

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