Class information for:
Level 2: CATALYTIC ANTIBODIES//ABZYME//DIRECTED EVOLUTION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2423 4132 38.4 75%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
239 3       LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS 47598
2423 2             CATALYTIC ANTIBODIES//ABZYME//DIRECTED EVOLUTION 4132
8400 1                   CATALYTIC ANTIBODIES//ABZYME//CHEM IMMUNOL THER EUT 1256
10724 1                   COMBINATORIAL CATALYSIS//HIGH THROUGHPUT EXPERIMENTATION//COMBINATORIAL 1040
10945 1                   DIRECTED EVOLUTION//DNA SHUFFLING//RANDOM MUTAGENESIS 1022
19390 1                   ARTIFICIAL METALLOENZYMES//BIOHYBRID CATALYSIS//CHEMOGENETIC OPTIMIZATION 507
24597 1                   ACTIVITY FINGERPRINT//2D FLUORESEENCE SPECTROSCOPY//ADRENALIN TEST AND COPPER CALCEIN ASSAY FOR AMINO ACIDS 307

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CATALYTIC ANTIBODIES authKW 1475452 7% 74% 270
2 ABZYME authKW 589907 2% 87% 92
3 DIRECTED EVOLUTION authKW 445417 7% 22% 272
4 ARTIFICIAL METALLOENZYMES authKW 248373 1% 82% 41
5 COMBINATORIAL CATALYSIS authKW 202991 1% 60% 46
6 HIGH THROUGHPUT EXPERIMENTATION authKW 142068 1% 34% 56
7 DNA SHUFFLING authKW 123247 1% 32% 52
8 COMBINATORIAL CHEMISTRY authKW 108828 4% 9% 157
9 COMBINATORIAL authKW 103415 2% 21% 68
10 CHEM IMMUNOL THER EUT address 94561 0% 80% 16

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Multidisciplinary 6145 27% 0% 1099
2 Biochemistry & Molecular Biology 3439 27% 0% 1113
3 Biotechnology & Applied Microbiology 2192 11% 0% 456
4 Chemistry, Medicinal 1942 7% 0% 294
5 Chemistry, Applied 1399 6% 0% 256
6 Chemistry, Organic 1242 9% 0% 387
7 Biochemical Research Methods 1203 7% 0% 272
8 Materials Science, Coatings & Films 434 3% 0% 116
9 Biophysics 365 5% 0% 187
10 Chemistry, Physical 360 9% 0% 392

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEM IMMUNOL THER EUT 94561 0% 80% 16
2 LIFE SCI BIOMOL ENGN 56743 0% 59% 13
3 MINIST PUBL HLTH RUSSIAN FEDERAT 56743 0% 59% 13
4 BIOSCI COMBICHEM CHARACTERIZAT TECHNOL 45250 0% 88% 7
5 STRUCT MECHANIST ENZYMOL 36366 0% 62% 8
6 CHEM BIOL FUNDAMENTAL MED 33167 2% 7% 63
7 CHEM CHEM ENGN 210 41 32891 0% 32% 14
8 CHEM IMMUNOL 31370 1% 17% 25
9 SMARTSTATE STRATEG PROACHES GENERAT ELECT 30782 0% 83% 5
10 UNITE MIXTE RECH 6022 29552 0% 100% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF COMBINATORIAL CHEMISTRY 21378 2% 5% 63
2 CURRENT OPINION IN CHEMICAL BIOLOGY 8603 1% 3% 47
3 ACS COMBINATORIAL SCIENCE 8363 1% 5% 25
4 QSAR & COMBINATORIAL SCIENCE 7400 1% 4% 25
5 CHEMBIOCHEM 7350 2% 2% 67
6 PROTEIN ENGINEERING DESIGN & SELECTION 6780 1% 3% 31
7 JOURNAL OF MOLECULAR RECOGNITION 5401 1% 2% 30
8 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 4710 4% 0% 161
9 PROTEIN ENGINEERING 4409 1% 2% 37
10 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 3702 1% 2% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CATALYTIC ANTIBODIES 1475452 7% 74% 270 Search CATALYTIC+ANTIBODIES Search CATALYTIC+ANTIBODIES
2 ABZYME 589907 2% 87% 92 Search ABZYME Search ABZYME
3 DIRECTED EVOLUTION 445417 7% 22% 272 Search DIRECTED+EVOLUTION Search DIRECTED+EVOLUTION
4 ARTIFICIAL METALLOENZYMES 248373 1% 82% 41 Search ARTIFICIAL+METALLOENZYMES Search ARTIFICIAL+METALLOENZYMES
5 COMBINATORIAL CATALYSIS 202991 1% 60% 46 Search COMBINATORIAL+CATALYSIS Search COMBINATORIAL+CATALYSIS
6 HIGH THROUGHPUT EXPERIMENTATION 142068 1% 34% 56 Search HIGH+THROUGHPUT+EXPERIMENTATION Search HIGH+THROUGHPUT+EXPERIMENTATION
7 DNA SHUFFLING 123247 1% 32% 52 Search DNA+SHUFFLING Search DNA+SHUFFLING
8 COMBINATORIAL CHEMISTRY 108828 4% 9% 157 Search COMBINATORIAL+CHEMISTRY Search COMBINATORIAL+CHEMISTRY
9 COMBINATORIAL 103415 2% 21% 68 Search COMBINATORIAL Search COMBINATORIAL
10 HIGH THROUGHPUT SCREENING 88128 5% 6% 187 Search HIGH+THROUGHPUT+SCREENING Search HIGH+THROUGHPUT+SCREENING

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BLACKBURN, GM , DATTA, A , DENHAM, H , WENTWORTH, P , (1998) CATALYTIC ANTIBODIES.ADVANCES IN PHYSICAL ORGANIC CHEMISTRY, VOL 31. VOL. 31. ISSUE . P. 249 -392 175 81% 28
2 MAIER, WF , STOWE, K , SIEG, S , (2007) COMBINATORIAL AND HIGH-THROUGHPUT MATERIALS SCIENCE.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 46. ISSUE 32. P. 6016 -6067 162 53% 153
3 NEVINSKY, GA , BUNEVA, VN , (2010) NATURAL CATALYTIC ANTIBODIES IN NORM, AUTOIMMUNE, VIRAL, AND BACTERIAL DISEASES.THESCIENTIFICWORLDJOURNAL. VOL. 10. ISSUE . P. 1203 -1233 107 79% 9
4 FARRUSSENG, D , (2008) HIGH-THROUGHPUT HETEROGENEOUS CATALYSIS.SURFACE SCIENCE REPORTS. VOL. 63. ISSUE 11. P. 487 -513 128 60% 45
5 TANAKA, F , (2002) CATALYTIC ANTIBODIES AS DESIGNER PROTEASES AND ESTERASES.CHEMICAL REVIEWS. VOL. 102. ISSUE 12. P. 4885 -4906 101 86% 53
6 LEWIS, JC , (2013) ARTIFICIAL METALLOENZYMES AND METALLOPEPTIDE CATALYSTS FOR ORGANIC SYNTHESIS.ACS CATALYSIS. VOL. 3. ISSUE 12. P. 2954-2975 95 49% 74
7 DEUSS, PJ , DEN HEETEN, R , LAAN, W , KAMER, PCJ , (2011) BIOINSPIRED CATALYST DESIGN AND ARTIFICIAL METALLOENZYMES.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 17. ISSUE 17. P. 4680-4698 99 48% 103
8 PAMIES, O , DIEGUEZ, M , BACKVALL, JE , (2015) ARTIFICIAL METALLOENZYMES IN ASYMMETRIC CATALYSIS: KEY DEVELOPMENTS AND FUTURE DIRECTIONS.ADVANCED SYNTHESIS & CATALYSIS. VOL. 357. ISSUE 8. P. 1567 -1586 75 66% 10
9 STEVENSON, JD , THOMAS, NR , (2000) CATALYTIC ANTIBODIES AND OTHER BIOMIMETIC CATALYSTS.NATURAL PRODUCT REPORTS. VOL. 17. ISSUE 6. P. 535 -577 144 53% 54
10 KOSTRIKINA, IA , BUNEVA, VN , NEVINSKY, GA , (2014) SYSTEMIC LUPUS ERYTHEMATOSUS: MOLECULAR CLONING OF FOURTEEN RECOMBINANT DNASE MONOCLONAL KAPPA LIGHT CHAINS WITH DIFFERENT CATALYTIC PROPERTIES.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1840. ISSUE 6. P. 1725-1737 61 91% 1

Classes with closest relation at Level 2


Rank Class id link
1 1834 PHAGE DISPLAY//ANTIBODY ENGINEERING//BISPECIFIC ANTIBODY
2 1994 KINETIC RESOLUTION//DYNAMIC KINETIC RESOLUTION//TETRAHEDRON-ASYMMETRY
3 3141 EPOXIDE HYDROLASE//HALOALKANE DEHALOGENASE//DEHALOGENASE
4 2176 LIPASE//UPR 9025//COLIPASE
5 2622 TRIOSEPHOSPHATE ISOMERASE//HISTIDINE BIOSYNTHESIS//KETOSTEROID ISOMERASE
6 3617 Q BETA REPLICASE//NICOTINE VACCINE//IMMUNOPHARMACOTHERAPY
7 1537 CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING
8 2636 COILED COIL//KRAB DOMAIN//PROTEIN DESIGN
9 3021 SHIKIMATE PATHWAY//CHORISMATE MUTASE//ANTHRANILATE SYNTHASE
10 3053 NITRILE HYDRATASE//NITRILASE//AMIDASE

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