Class information for:
Level 1: METALLO BETA LACTAMASE//INGN PROT//ZINC BETA LACTAMASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18692 540 42.5 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
682 3       BETA LACTAMS//BETA LACTAMASE//INGN PROT 8575
1556 2             BETA LACTAMS//BETA LACTAMASE//INGN PROT 7389
18692 1                   METALLO BETA LACTAMASE//INGN PROT//ZINC BETA LACTAMASE 540

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METALLO BETA LACTAMASE authKW 2052422 24% 28% 132
2 INGN PROT address 346890 9% 13% 47
3 ZINC BETA LACTAMASE authKW 339275 1% 100% 6
4 STRUCT FUNCT PHYS CHEM address 307857 1% 78% 7
5 METALLO BETA LACTAMASE CCRA authKW 226183 1% 100% 4
6 BIOMED EPR address 183754 2% 25% 13
7 ANTIBIOTIC HYDROLYSIS authKW 180945 1% 80% 4
8 BINUCLEAR ZINC authKW 169637 1% 100% 3
9 INGN PROT B6 address 169637 1% 100% 3
10 METALLO SS LACTAMASES authKW 169637 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Microbiology 1882 25% 0% 137
2 Biochemistry & Molecular Biology 1428 44% 0% 236
3 Chemistry, Medicinal 755 12% 0% 63
4 Pharmacology & Pharmacy 651 22% 0% 119
5 Biophysics 188 8% 0% 42
6 Chemistry, Inorganic & Nuclear 128 6% 0% 35
7 Chemistry, Organic 66 7% 0% 36
8 Infectious Diseases 66 4% 0% 22
9 Chemistry, Multidisciplinary 63 10% 0% 54
10 Biochemical Research Methods 53 4% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INGN PROT 346890 9% 13% 47
2 STRUCT FUNCT PHYS CHEM 307857 1% 78% 7
3 BIOMED EPR 183754 2% 25% 13
4 INGN PROT B6 169637 1% 100% 3
5 NORWEGIAN STRUCT BIOL NORSTRUCT 152812 2% 27% 10
6 CHRISTOPHER S KIT BOND SCI TECHNOL INCUBATOR 113092 0% 100% 2
7 SOPHARMIA INC 113092 0% 100% 2
8 DIPARTIMENTO BIOL MOL 113040 5% 7% 28
9 BIOL MOL CELULAR ROSARIO IBR 89458 2% 13% 12
10 CHIM B6 88783 3% 9% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 17300 16% 0% 85
2 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 2262 2% 0% 9
3 BIOCHEMISTRY 1488 7% 0% 38
4 PROTEIN SCIENCE 1073 2% 0% 11
5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 869 4% 0% 20
6 JOURNAL OF INORGANIC BIOCHEMISTRY 630 1% 0% 8
7 FUTURE MEDICINAL CHEMISTRY 552 1% 0% 3
8 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 530 2% 0% 11
9 ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 454 1% 0% 5
10 BIOCHEMICAL JOURNAL 413 3% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METALLO BETA LACTAMASE 2052422 24% 28% 132 Search METALLO+BETA+LACTAMASE Search METALLO+BETA+LACTAMASE
2 ZINC BETA LACTAMASE 339275 1% 100% 6 Search ZINC+BETA+LACTAMASE Search ZINC+BETA+LACTAMASE
3 METALLO BETA LACTAMASE CCRA 226183 1% 100% 4 Search METALLO+BETA+LACTAMASE+CCRA Search METALLO+BETA+LACTAMASE+CCRA
4 ANTIBIOTIC HYDROLYSIS 180945 1% 80% 4 Search ANTIBIOTIC+HYDROLYSIS Search ANTIBIOTIC+HYDROLYSIS
5 BINUCLEAR ZINC 169637 1% 100% 3 Search BINUCLEAR+ZINC Search BINUCLEAR+ZINC
6 METALLO SS LACTAMASES 169637 1% 100% 3 Search METALLO+SS+LACTAMASES Search METALLO+SS+LACTAMASES
7 MERCAPTOACETIC ACID THIOESTER 113092 0% 100% 2 Search MERCAPTOACETIC+ACID+THIOESTER Search MERCAPTOACETIC+ACID+THIOESTER
8 COII SUBSTITUTION 84816 1% 50% 3 Search COII+SUBSTITUTION Search COII+SUBSTITUTION
9 BISTHIAZOLIDINES 75393 0% 67% 2 Search BISTHIAZOLIDINES Search BISTHIAZOLIDINES
10 PENICILLIN BINDING 75393 0% 67% 2 Search PENICILLIN+BINDING Search PENICILLIN+BINDING

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KARSISIOTIS, AI , DAMBLON, CF , ROBERTS, GCK , (2014) A VARIETY OF ROLES FOR VERSATILE ZINC IN METALLO-BETA-LACTAMASES.METALLOMICS. VOL. 6. ISSUE 7. P. 1181 -1197 104 87% 20
2 MEINI, MR , LLARRULL, LI , VILA, AJ , (2015) OVERCOMING DIFFERENCES: THE CATALYTIC MECHANISM OF METALLO-BETA-LACTAMASES.FEBS LETTERS. VOL. 589. ISSUE 22. P. 3419 -3432 82 73% 8
3 FAST, W , SUTTON, LD , (2013) METALLO-BETA-LACTAMASE: INHIBITORS AND REPORTER SUBSTRATES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1834. ISSUE 8. P. 1648 -1659 78 76% 32
4 PALZKILL, T , (2013) METALLO-BETA-LACTAMASE STRUCTURE AND FUNCTION.ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET. VOL. 1277. ISSUE . P. 91-104 69 68% 62
5 HEINZ, U , ADOLPH, HW , (2004) METALLO-BETA-LACTAMASES: TWO BINDING SITES FOR ONE CATALYTIC METAL ION?.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 61. ISSUE 22. P. 2827-2839 94 73% 56
6 CROWDER, MW , SPENCER, J , VILA, AJ , (2006) METALLO-BETA-LACTAMASES: NOVEL WEAPONRY FOR ANTIBIOTIC RESISTANCE IN BACTERIA.ACCOUNTS OF CHEMICAL RESEARCH. VOL. 39. ISSUE 10. P. 721-728 61 92% 123
7 COSTELLO, AL , SHARMA, NP , YANG, KW , CROWDER, MW , TIERNEY, DL , (2006) X-RAY ABSORPTION SPECTROSCOPY OF THE ZINC-BINDING SITES IN THE CLASS B2 METALLO-BETA-LACTAMASE IMIS FROM AEROMONAS VERONII BV. SOBRIA.BIOCHEMISTRY. VOL. 45. ISSUE 45. P. 13650-13658 70 92% 20
8 MOJICA, MF , BONOMO, RA , FAST, W , (2016) B1-METALLO-BETA-LACTAMASES: WHERE DO WE STAND?.CURRENT DRUG TARGETS. VOL. 17. ISSUE 9. P. 1029 -1050 84 54% 0
9 GUO, ZZ , MA, ST , (2014) RECENT ADVANCES IN THE DISCOVERY OF METALLO-BETA-LACTAMASE INHIBITORS FOR BETA-LACTAM ANTIBIOTIC-RESISTANT REVERSING AGENTS.CURRENT DRUG TARGETS. VOL. 15. ISSUE 7. P. 689-702 67 68% 5
10 GAHAN, LR , DAUMANN, LJ , SCHENK, G , (2014) METALLO-BETA-LACTAMASES AND THEIR BIOMIMETIC COMPLEXES.EUROPEAN JOURNAL OF INORGANIC CHEMISTRY. VOL. . ISSUE 18. P. 2869 -2885 78 60% 2

Classes with closest relation at Level 1


Rank Class id link
1 4087 BETA LACTAMASE//PENICILLIN BINDING PROTEIN//INGN PROT
2 1324 CARBAPENEMASE//METALLO BETA LACTAMASE//KPC
3 18064 ELIZABETHKINGIA MENINGOSEPTICA//CHRYSEOBACTERIUM INDOLOGENES//CHRYSEOBACTERIUM MENINGOSEPTICUM
4 22341 AVIBACTAM//CEFTOLOZANE TAZOBACTAM//CEFTAZIDIME AVIBACTAM
5 22062 3S 5R 6R 6 ACETYLAMIDOPENICILLANIC ACID//BETA LACTAM COMPOUNDS//BIOL VET BIOQUIM BIOL MOLEC
6 21098 CARBOXYPEPTIDASE A//GENERAL ACID GENERAL BASE//5 BROMOACETYLSALICYLIC ACID
7 14262 STENOTROPHOMONAS MALTOPHILIA//S MALTOPHILIA//XANTHOMONAS MALTOPHILIA
8 15484 PURPLE ACID PHOSPHATASE//TARTRATE RESISTANT ACID PHOSPHATASE//SPECIAL HEMATOL
9 6255 BACTEROIDES FRAGILIS//CFIA//ENTEROTOXIGENIC BACTEROIDES FRAGILIS
10 26991 DRUG DESIGN BIOTECHNOL//METAL BINDING RESIDUES//METAL CATIONS M2

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