Class information for:
Level 1: BETA LACTAMASE//PENICILLIN BINDING PROTEIN//INGN PROT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4087 1849 37.8 72%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
682 3       BETA LACTAMS//BETA LACTAMASE//INGN PROT 8575
1556 2             BETA LACTAMS//BETA LACTAMASE//INGN PROT 7389
4087 1                   BETA LACTAMASE//PENICILLIN BINDING PROTEIN//INGN PROT 1849

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BETA LACTAMASE authKW 484585 11% 14% 206
2 PENICILLIN BINDING PROTEIN authKW 307451 4% 25% 75
3 INGN PROT address 218270 4% 19% 69
4 DD PEPTIDASE authKW 185761 1% 75% 15
5 BETA LACTAMASE INHIBITORS authKW 132867 2% 22% 36
6 GRP CRISTALLOG BIOL address 108373 1% 41% 16
7 CLASS C BETA LACTAMASE authKW 84921 0% 86% 6
8 PHARMACOL MOL BIOL MICROBIOL address 57788 0% 50% 7
9 CHIM B6 address 56046 1% 14% 25
10 PENAM SULFONE authKW 49538 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 6774 50% 0% 933
2 Microbiology 6325 25% 0% 465
3 Pharmacology & Pharmacy 1735 20% 0% 366
4 Chemistry, Medicinal 846 7% 0% 130
5 Biophysics 794 8% 0% 157
6 Chemistry, Organic 275 7% 0% 132
7 Biochemical Research Methods 142 4% 0% 72
8 Infectious Diseases 137 3% 0% 62
9 Biotechnology & Applied Microbiology 96 5% 0% 85
10 Chemistry, Multidisciplinary 72 7% 0% 135

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INGN PROT 218270 4% 19% 69
2 GRP CRISTALLOG BIOL 108373 1% 41% 16
3 PHARMACOL MOL BIOL MICROBIOL 57788 0% 50% 7
4 CHIM B6 56046 1% 14% 25
5 INGN PROT PEPTIDES 37152 0% 75% 3
6 ANDROGEN RECEPTOR 33026 0% 100% 2
7 REFERENCE MONITORING ANTIMICROBIAL ISTANCE 33026 0% 100% 2
8 LOUIS STOKES CLEVELAND 30974 1% 9% 20
9 DRUG ISTANCE PROTE 26416 0% 40% 4
10 RECH MICROBIOL 26416 0% 40% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 21033 9% 1% 174
2 BIOCHEMICAL JOURNAL 11944 8% 1% 146
3 BIOCHEMISTRY 10108 10% 0% 182
4 JOURNAL OF ANTIBIOTICS 6898 3% 1% 53
5 PROTEINS-STRUCTURE FUNCTION AND GENETICS 2995 0% 2% 9
6 JOURNAL OF MOLECULAR BIOLOGY 1835 3% 0% 52
7 PROTEIN ENGINEERING 1616 1% 1% 15
8 FEMS MICROBIOLOGY LETTERS 1602 2% 0% 40
9 ACS INFECTIOUS DISEASES 1574 0% 2% 4
10 MICROBIOS 1508 1% 1% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BETA LACTAMASE 484585 11% 14% 206 Search BETA+LACTAMASE Search BETA+LACTAMASE
2 PENICILLIN BINDING PROTEIN 307451 4% 25% 75 Search PENICILLIN+BINDING+PROTEIN Search PENICILLIN+BINDING+PROTEIN
3 DD PEPTIDASE 185761 1% 75% 15 Search DD+PEPTIDASE Search DD+PEPTIDASE
4 BETA LACTAMASE INHIBITORS 132867 2% 22% 36 Search BETA+LACTAMASE+INHIBITORS Search BETA+LACTAMASE+INHIBITORS
5 CLASS C BETA LACTAMASE 84921 0% 86% 6 Search CLASS+C+BETA+LACTAMASE Search CLASS+C+BETA+LACTAMASE
6 PENAM SULFONE 49538 0% 100% 3 Search PENAM+SULFONE Search PENAM+SULFONE
7 SERINE BETA LACTAMASE 49538 0% 100% 3 Search SERINE+BETA+LACTAMASE Search SERINE+BETA+LACTAMASE
8 TEM 1 47757 0% 32% 9 Search TEM+1 Search TEM+1
9 DD CARBOXYPEPTIDASE 45864 0% 56% 5 Search DD+CARBOXYPEPTIDASE Search DD+CARBOXYPEPTIDASE
10 CLASS A BETA LACTAMASE 45721 0% 46% 6 Search CLASS+A+BETA+LACTAMASE Search CLASS+A+BETA+LACTAMASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DRAWZ, SM , BONOMO, RA , (2010) THREE DECADES OF BETA-LACTAMASE INHIBITORS.CLINICAL MICROBIOLOGY REVIEWS. VOL. 23. ISSUE 1. P. 160-+ 208 55% 374
2 MATAGNE, A , LAMOTTE-BRASSEUR, J , FRERE, JM , (1998) CATALYTIC PROPERTIES OF CLASS A BETA-LACTAMASES: EFFICIENCY AND DIVERSITY.BIOCHEMICAL JOURNAL. VOL. 330. ISSUE . P. 581 -598 120 68% 242
3 FISHER, JF , MEROUEH, SO , MOBASHERY, S , (2005) BACTERIAL RESISTANCE TO BETA-LACTAM ANTIBIOTICS: COMPELLING OPPORTUNISM, COMPELLING OPPORTUNITY.CHEMICAL REVIEWS. VOL. 105. ISSUE 2. P. 395-424 126 35% 456
4 MATAGNE, A , DUBUS, A , GALLENI, M , FRERE, JM , (1999) THE BETA-LACTAMASE CYCLE: A TALE OF SELECTIVE PRESSURE AND BACTERIAL INGENUITY.NATURAL PRODUCT REPORTS. VOL. 16. ISSUE 1. P. 1 -19 118 58% 139
5 PRATT, RF , (2002) FUNCTIONAL EVOLUTION OF THE SERINE BETA-LACTAMASE ACTIVE SITE.JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2. VOL. . ISSUE 5. P. 851 -861 83 82% 33
6 MATAGNE, A , FRERE, JM , (1995) CONTRIBUTION OF MUTANT ANALYSIS TO THE UNDERSTANDING OF ENZYME CATALYSIS - THE CASE OF CLASS-A BETA-LACTAMASES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY. VOL. 1246. ISSUE 2. P. 109-127 82 88% 87
7 FENOLLAR-FERRER, C , FRAU, J , DONOSO, J , MUNOZ, F , (2008) EVOLUTION OF CLASS C BETA-LACTAMASES: FACTORS INFLUENCING THEIR HYDROLYSIS AND RECOGNITION MECHANISMS.THEORETICAL CHEMISTRY ACCOUNTS. VOL. 121. ISSUE 3-4. P. 209-218 59 87% 6
8 PRATT, RF , (2016) BETA-LACTAMASES: WHY AND HOW.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 18. P. 8207 -8220 60 71% 0
9 PRATT, RF , (2008) SUBSTRATE SPECIFICITY OF BACTERIAL DD-PEPTIDASES (PENICILLIN-BINDING PROTEINS).CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 65. ISSUE 14. P. 2138-2155 78 59% 33
10 BEBRONE, C , LASSAUX, P , VERCHEVAL, L , SOHIER, JS , JEHAES, A , SAUVAGE, E , GALLENI, M , (2010) CURRENT CHALLENGES IN ANTIMICROBIAL CHEMOTHERAPY FOCUS ON BETA-LACTAMASE INHIBITION.DRUGS. VOL. 70. ISSUE 6. P. 651 -679 83 48% 64

Classes with closest relation at Level 1


Rank Class id link
1 18692 METALLO BETA LACTAMASE//INGN PROT//ZINC BETA LACTAMASE
2 22062 3S 5R 6R 6 ACETYLAMIDOPENICILLANIC ACID//BETA LACTAM COMPOUNDS//BIOL VET BIOQUIM BIOL MOLEC
3 29696 LRMA//EQUIPE 12//L D TRANSPEPTIDASE
4 22341 AVIBACTAM//CEFTOLOZANE TAZOBACTAM//CEFTAZIDIME AVIBACTAM
5 11325 CLASS I BETA LACTAMASE//JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//2 KETO 3 DEOXY OCTONATE
6 99 EXTENDED SPECTRUM BETA LACTAMASE//ESBL//CTX M
7 11826 SULBACTAM//SULTAMICILLIN//AMPICILLIN SULBACTAM
8 9905 LYTIC TRANSGLYCOSYLASE//MUREIN//MUROPEPTIDES
9 33141 NYLON OLIGOMER//6 AMINOHEXANOATE DIMER HYDROLASE//CAP PLASMIDS
10 10027 MECA GENE//MECA//CEFOXITIN

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