Class information for:
Level 2: BETA LACTAMS//BETA LACTAMASE//INGN PROT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1556 7389 30.7 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
682 3       BETA LACTAMS//BETA LACTAMASE//INGN PROT 8575
1556 2             BETA LACTAMS//BETA LACTAMASE//INGN PROT 7389
4087 1                   BETA LACTAMASE//PENICILLIN BINDING PROTEIN//INGN PROT 1849
4751 1                   BETA LACTAMS//2 AZETIDINONE//STAUDINGER REACTION 1733
6555 1                   1 BETA METHYLCARBAPENEM//5 OXACEPHAMS//TRINEMS 1470
15535 1                   AZOMETHINE IMINES//PYRAZOLIDINONES//1 5 DIAZABICYCLO310HEXANES 707
15727 1                   AS 924//CEFCAPENE PIVOXIL//ORAL CEPHALOSPORIN 695
18692 1                   METALLO BETA LACTAMASE//INGN PROT//ZINC BETA LACTAMASE 540
22062 1                   3S 5R 6R 6 ACETYLAMIDOPENICILLANIC ACID//BETA LACTAM COMPOUNDS//BIOL VET BIOQUIM BIOL MOLEC 395

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BETA LACTAMS authKW 350953 5% 24% 355
2 BETA LACTAMASE authKW 165626 3% 17% 241
3 INGN PROT address 159604 2% 33% 118
4 METALLO BETA LACTAMASE authKW 156640 2% 28% 135
5 2 AZETIDINONE authKW 145252 1% 64% 55
6 1 BETA METHYLCARBAPENEM authKW 144645 1% 85% 41
7 STAUDINGER REACTION authKW 131776 1% 38% 84
8 AZOMETHINE IMINES authKW 91019 1% 57% 39
9 AZETIDIN 2 ONES authKW 88991 1% 57% 38
10 AZETIDINONES authKW 87250 1% 35% 61

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Organic 53706 39% 1% 2862
2 Chemistry, Medicinal 7914 10% 0% 762
3 Chemistry, Multidisciplinary 6144 21% 0% 1536
4 Microbiology 5518 13% 0% 932
5 Pharmacology & Pharmacy 3764 15% 0% 1136
6 Biochemistry & Molecular Biology 2026 18% 0% 1316
7 Biotechnology & Applied Microbiology 504 5% 0% 371
8 Crystallography 489 3% 0% 211
9 Immunology 229 5% 0% 343
10 Biophysics 154 3% 0% 209

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INGN PROT 159604 2% 33% 118
2 CHIM B6 39535 1% 23% 42
3 STRUCT FUNCT PHYS CHEM 29371 0% 89% 8
4 GRP CRISTALLOG BIOL 27095 0% 41% 16
5 QUIM ORGAN 1 21994 1% 8% 69
6 MOL ERS DRUG DESIGN DISCOVERY DELIVERY 15286 0% 37% 10
7 PHARMACOL MOL BIOL MICROBIOL 14450 0% 50% 7
8 NORWEGIAN STRUCT BIOL NORSTRUCT 13493 0% 30% 11
9 BIOMED EPR 13405 0% 25% 13
10 UMR RELAT HOTE PARASITES PHYSIOPATHOL PHARMACOL 13216 0% 80% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ANTIBIOTICS 64445 4% 5% 323
2 TETRAHEDRON LETTERS 21133 8% 1% 621
3 HETEROCYCLES 15698 3% 2% 226
4 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 14691 4% 1% 294
5 JOURNAL OF ORGANIC CHEMISTRY 9355 5% 1% 349
6 TETRAHEDRON 9238 4% 1% 294
7 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 7042 2% 1% 141
8 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 6119 3% 1% 198
9 JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS 4145 2% 1% 134
10 BIOCHEMICAL JOURNAL 3542 2% 1% 164

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BETA LACTAMS 350953 5% 24% 355 Search BETA+LACTAMS Search BETA+LACTAMS
2 BETA LACTAMASE 165626 3% 17% 241 Search BETA+LACTAMASE Search BETA+LACTAMASE
3 METALLO BETA LACTAMASE 156640 2% 28% 135 Search METALLO+BETA+LACTAMASE Search METALLO+BETA+LACTAMASE
4 2 AZETIDINONE 145252 1% 64% 55 Search 2+AZETIDINONE Search 2+AZETIDINONE
5 1 BETA METHYLCARBAPENEM 144645 1% 85% 41 Search 1+BETA+METHYLCARBAPENEM Search 1+BETA+METHYLCARBAPENEM
6 STAUDINGER REACTION 131776 1% 38% 84 Search STAUDINGER+REACTION Search STAUDINGER+REACTION
7 AZOMETHINE IMINES 91019 1% 57% 39 Search AZOMETHINE+IMINES Search AZOMETHINE+IMINES
8 AZETIDIN 2 ONES 88991 1% 57% 38 Search AZETIDIN+2+ONES Search AZETIDIN+2+ONES
9 AZETIDINONES 87250 1% 35% 61 Search AZETIDINONES Search AZETIDINONES
10 PENICILLIN BINDING PROTEIN 80979 1% 25% 77 Search PENICILLIN+BINDING+PROTEIN Search PENICILLIN+BINDING+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DRAWZ, SM , BONOMO, RA , (2010) THREE DECADES OF BETA-LACTAMASE INHIBITORS.CLINICAL MICROBIOLOGY REVIEWS. VOL. 23. ISSUE 1. P. 160-+ 236 62% 374
2 FARINA, D , SPYRAKIS, F , VENTURELLI, A , CROSS, S , TONDI, D , COSTI, MP , (2014) THE INHIBITION OF EXTENDED SPECTRUM BETA-LACTAMASES: HITS AND LEADS.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 12. P. 1405 -1434 162 72% 5
3 KARSISIOTIS, AI , DAMBLON, CF , ROBERTS, GCK , (2014) A VARIETY OF ROLES FOR VERSATILE ZINC IN METALLO-BETA-LACTAMASES.METALLOMICS. VOL. 6. ISSUE 7. P. 1181 -1197 105 88% 20
4 ARANDA, MT , PEREZ-FAGINAS, P , GONZALEZ-MUNIZ, R , (2009) AN UPDATE ON THE SYNTHESIS OF BETA-LACTAMS.CURRENT ORGANIC SYNTHESIS. VOL. 6. ISSUE 3. P. 325-341 146 67% 42
5 FISHER, JF , MEROUEH, SO , MOBASHERY, S , (2005) BACTERIAL RESISTANCE TO BETA-LACTAM ANTIBIOTICS: COMPELLING OPPORTUNISM, COMPELLING OPPORTUNITY.CHEMICAL REVIEWS. VOL. 105. ISSUE 2. P. 395-424 163 45% 456
6 PALZKILL, T , (2013) METALLO-BETA-LACTAMASE STRUCTURE AND FUNCTION.ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET. VOL. 1277. ISSUE . P. 91-104 84 82% 62
7 XU, JX , (2012) SYNTHESIS OF BETA-LACTAMS WITH PI ELECTRON-WITHDRAWING SUBSTITUENTS.TETRAHEDRON. VOL. 68. ISSUE 52. P. 10696-10747 155 55% 19
8 PALOMO, C , AIZPURUA, JM , GANBOA, I , OIARBIDE, M , (1999) ASYMMETRIC SYNTHESIS OF BETA-LACTAMS BY STAUDINGER KETENE-IMINE CYCLOADDITION REACTION.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. VOL. . ISSUE 12. P. 3223 -3235 108 89% 248
9 BEBRONE, C , LASSAUX, P , VERCHEVAL, L , SOHIER, JS , JEHAES, A , SAUVAGE, E , GALLENI, M , (2010) CURRENT CHALLENGES IN ANTIMICROBIAL CHEMOTHERAPY FOCUS ON BETA-LACTAMASE INHIBITION.DRUGS. VOL. 70. ISSUE 6. P. 651 -679 116 67% 64
10 FAST, W , SUTTON, LD , (2013) METALLO-BETA-LACTAMASE: INHIBITORS AND REPORTER SUBSTRATES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1834. ISSUE 8. P. 1648 -1659 85 83% 32

Classes with closest relation at Level 2


Rank Class id link
1 451 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//CHEMOTHERAPY-TOKYO
2 2025 FTSZ//PEPTIDOGLYCAN//BACTERIAL CELL DIVISION
3 233 ACINETOBACTER BAUMANNII//EXTENDED SPECTRUM BETA LACTAMASE//ESBL
4 2545 AZIRIDINES//AZIRIDINATION//AZETIDINES
5 1937 AZOMETHINE YLIDE//1 3 DIPOLAR CYCLOADDITION//NITRILE OXIDES
6 2990 1 2 OXAZINES//1 2 DIAZA 1 3 BUTADIENES//IST CHIM ORGAN
7 3060 SULTAMS//BETA SULTAMS//SULTONES
8 1906 ALPHA 1 ANTITRYPSIN DEFICIENCY//ALPHA 1 ANTITRYPSIN//ALPHA1 ANTITRYPSIN DEFICIENCY
9 2075 CHEMISTRY, ORGANIC//ACROMELIC ACID//PHASE TRANSFER CATALYSIS
10 2596 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//ACTA CRYSTALLOGRAPHICA SECTION A//ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY

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