Class information for:
Level 1: CYCLOOXYGENASE 2//COX 2//CELECOXIB

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
180 4006 45.2 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
275 3       NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 43399
2305 2             CYCLOOXYGENASE 2//COX 2//CELECOXIB 4519
180 1                   CYCLOOXYGENASE 2//COX 2//CELECOXIB 4006

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYCLOOXYGENASE 2 authKW 695223 14% 16% 564
2 COX 2 authKW 590348 12% 16% 497
3 CELECOXIB authKW 515923 8% 22% 309
4 SULINDAC authKW 218870 2% 35% 82
5 NSAIDS authKW 126592 6% 7% 241
6 CYCLOOXYGENASE authKW 117805 6% 7% 232
7 ASPIRIN authKW 115667 7% 5% 288
8 COX 2 INHIBITORS authKW 95660 2% 14% 89
9 CHEMOPREVENTION authKW 94249 5% 6% 219
10 NS 398 authKW 89350 1% 27% 44

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 41159 52% 0% 2093
2 Gastroenterology & Hepatology 3617 10% 0% 391
3 Pathology 950 5% 0% 201
4 Cell Biology 519 8% 0% 315
5 Medicine, Research & Experimental 429 5% 0% 202
6 Pharmacology & Pharmacy 401 8% 0% 340
7 Biochemistry & Molecular Biology 95 9% 0% 366
8 Public, Environmental & Occupational Health 90 3% 0% 137
9 Urology & Nephrology 90 2% 0% 87
10 Medicine, General & Internal 88 4% 0% 160

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADV MICROSCOP DIS 22862 0% 100% 3
2 GASTROINTESTINAL OTHER CANC GRP 22159 0% 36% 8
3 HANGZHOU HOSP 17058 0% 20% 11
4 CLIN CANC PREVENT 236 15241 0% 100% 2
5 DEFINED TUMOR MARKER EVALUAT 15241 0% 100% 2
6 EICOSANOIDS TUMOR DEV SECT 15241 0% 100% 2
7 GASTROINTESTINAL OTHER CANCERS GRP 15241 0% 100% 2
8 PROGRAMA DOCTORADO MORFOL 15241 0% 100% 2
9 CANC PREVENT 14670 2% 2% 87
10 SECT EICOSANOIDS TUMOR DEV 13715 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER PREVENTION RESEARCH 14276 1% 4% 48
2 CANCER RESEARCH 6945 5% 1% 192
3 PROGRESS IN EXPERIMENTAL TUMOR RESEARCH 5178 0% 6% 12
4 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 4407 2% 1% 61
5 CARCINOGENESIS 4395 2% 1% 83
6 CLINICAL CANCER RESEARCH 4393 2% 1% 94
7 ONCOLOGY REPORTS 4319 2% 1% 76
8 ANTICANCER RESEARCH 3019 2% 0% 89
9 BRITISH JOURNAL OF CANCER 3011 2% 0% 86
10 INTERNATIONAL JOURNAL OF CANCER 2852 2% 0% 89

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYCLOOXYGENASE 2 695223 14% 16% 564 Search CYCLOOXYGENASE+2 Search CYCLOOXYGENASE+2
2 COX 2 590348 12% 16% 497 Search COX+2 Search COX+2
3 CELECOXIB 515923 8% 22% 309 Search CELECOXIB Search CELECOXIB
4 SULINDAC 218870 2% 35% 82 Search SULINDAC Search SULINDAC
5 NSAIDS 126592 6% 7% 241 Search NSAIDS Search NSAIDS
6 CYCLOOXYGENASE 117805 6% 7% 232 Search CYCLOOXYGENASE Search CYCLOOXYGENASE
7 ASPIRIN 115667 7% 5% 288 Search ASPIRIN Search ASPIRIN
8 COX 2 INHIBITORS 95660 2% 14% 89 Search COX+2+INHIBITORS Search COX+2+INHIBITORS
9 CHEMOPREVENTION 94249 5% 6% 219 Search CHEMOPREVENTION Search CHEMOPREVENTION
10 NS 398 89350 1% 27% 44 Search NS+398 Search NS+398

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 THUN, MJ , HENLEY, SJ , PATRONO, C , (2002) NONSTEROIDAL ANTI-INFLAMMATORY DRUGS AS ANTICANCER AGENTS: MECHANISTIC, PHARMACOLOGIC, AND CLINICAL ISSUES.JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 94. ISSUE 4. P. 252 -266 132 71% 850
2 BENAMOUZIG, R , UZZAN, B , LITTLE, J , CHAUSSADE, S , (2005) LOW DOSE ASPIRIN, COX-INHIBITION AND CHEMOPREVENTION OF COLORECTAL CANCER.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 5. ISSUE 5. P. 493-503 154 80% 10
3 UMAR, A , VINER, JL , ANDERSON, WF , HAWK, ET , (2003) DEVELOPMENT OF COX INHIBITORS IN CANCER PREVENTION AND THERAPY.AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS. VOL. 26. ISSUE 4. P. S48-S57 152 84% 18
4 ANDERSON, WF , UMAR, A , VINER, JL , HAWK, ET , (2002) THE ROLE OF CYCLOOXYGENASE INHIBITORS IN CANCER PREVENTION.CURRENT PHARMACEUTICAL DESIGN. VOL. 8. ISSUE 12. P. 1035 -1062 193 65% 48
5 LIAO, ZX , MASON, KA , MILAS, L , (2007) CYCLO-OXYGENASE-2 AND ITS INHIBITION IN CANCER - IS THERE A ROLE?.DRUGS. VOL. 67. ISSUE 6. P. 821 -845 147 71% 47
6 BOSETTI, C , ROSATO, V , GALLUS, S , CUZICK, J , LA VECCHIA, C , (2012) ASPIRIN AND CANCER RISK: A QUANTITATIVE REVIEW TO 2011.ANNALS OF ONCOLOGY. VOL. 23. ISSUE 6. P. 1403-1415 82 79% 111
7 BROWN, JR , DUBOIS, RN , (2005) COX-2: A MOLECULAR TARGET FOR COLORECTAL CANCER PREVENTION.JOURNAL OF CLINICAL ONCOLOGY. VOL. 23. ISSUE 12. P. 2840-2855 115 61% 289
8 HARRIS, RE , BEEBE-DONK, J , DOSS, H , DOSS, DB , (2005) ASPIRIN, IBUPROFEN, AND OTHER NON-STEROIDAL ANTI-INFLAMMATORY DRUGS IN CANCER PREVENTION: A CRITICAL REVIEW OF NON-SELECTIVE COX-2 BLOCKADE (REVIEW).ONCOLOGY REPORTS. VOL. 13. ISSUE 4. P. 559-583 125 58% 213
9 SUBONGKOT, S , FRAME, D , LESLIE, W , DRAJEEER, D , (2003) SELECTIVE CYCLOOXYGENASE-2 INHIBITION: A TARGET IN CANCER PREVENTION AND TREATMENT.PHARMACOTHERAPY. VOL. 23. ISSUE 1. P. 9-28 131 72% 26
10 ONGURU, O , CASEY, MB , KAJITA, S , NAKAMURA, N , LLOYD, RV , (2005) CYCLOOXYGENASE-2 AND THROMBOXANE SYNTHASE IN NON-ENDOCRINE AND ENDOCRINE TUMORS: A REVIEW.ENDOCRINE PATHOLOGY. VOL. 16. ISSUE 4. P. 253-277 114 78% 15

Classes with closest relation at Level 1


Rank Class id link
1 23913 PTGS2//CYCLOOXYGENASE 2 GENE//COX 2 POLYMORPHISM
2 36785 GRAPTOPETALUM PARAGUAYENSE E WALTHER//GRAPTOPETALUM PARAGUAYENSE//3 HYDROXYL 3 METHYLGLUTAROYL HMG
3 34596 CYCLOOXYGENASE 1 INHIBITOR//ANTIOXIDANT DEFENSE MECHANISM//BIOMED NETWORK HEPAT DIGEST DIS
4 19756 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 1 INHIBITORS
5 25991 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE//15 PGDH//15 HYDROXYPROSTAGLANDIN DEHYDROGENASE 15 PGDH
6 2243 CYCLOOXYGENASE//PROSTAGLANDIN H SYNTHASE//AB HANCOCK JR MEM CANC
7 17640 12S HETE//LY293111//ZYFLAMEND
8 21370 NO NSAIDS//NCX 4016//NO ASPIRIN
9 36100 SALICYLIDENEAMINO 2 THIOPHENOL//ALPHA AMINOPHENYL CEPHALOPSORINS//APO 27 MONOCLONAL ANTIBODY
10 11362 COXIBS//SOLUMATRIX//ROFECOXIB

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