Class information for:
Level 1: ACETAMINOPHEN//PARACETAMOL//HEPATOTOXICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1628 2562 36.6 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
547 3       ACETAMINOPHEN//CARBON MONOXIDE POISONING//POISONING 18371
1613 2             ACETAMINOPHEN//DRUG INDUCED LIVER INJURY//HEPATOTOXICITY 7077
1628 1                   ACETAMINOPHEN//PARACETAMOL//HEPATOTOXICITY 2562

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACETAMINOPHEN authKW 2240921 28% 26% 711
2 PARACETAMOL authKW 300762 9% 11% 229
3 HEPATOTOXICITY authKW 242142 11% 7% 275
4 ACETAMINOPHEN HEPATOTOXICITY authKW 202118 1% 81% 21
5 ACETAMINOPHEN APAP authKW 111878 1% 72% 13
6 PARACETAMOL POISONING authKW 108332 0% 91% 10
7 ACETAMINOPHEN TOXICITY authKW 107529 1% 48% 19
8 ACETAMINOPHEN OVERDOSE authKW 107245 0% 75% 12
9 NAPQI authKW 99303 0% 83% 10
10 ACETYLCYSTEINE authKW 76173 1% 17% 37

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Toxicology 23041 29% 0% 732
2 Pharmacology & Pharmacy 12251 41% 0% 1048
3 Gastroenterology & Hepatology 1760 9% 0% 221
4 Emergency Medicine 1113 3% 0% 76
5 Medicine, General & Internal 546 8% 0% 214
6 Pathology 146 3% 0% 73
7 Chemistry, Medicinal 144 3% 0% 77
8 Medicine, Research & Experimental 106 4% 0% 93
9 Medical Laboratory Technology 47 1% 0% 25
10 Integrative & Complementary Medicine 47 1% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOL TOXICOL THER EUT 66892 3% 7% 77
2 SECT CLIN PHARMACOL TOXICOL 49676 1% 30% 14
3 NPIS EDINBURGH 48050 0% 37% 11
4 MOL CELLULAR TOXICOL SECT 47933 1% 31% 13
5 SCOTTISH POISONS INFORMAT BUR 44126 1% 22% 17
6 CLIN TOXICOL PROGRAM 41702 0% 50% 7
7 WHO ABORATING DRUG INFORMAT 37930 0% 29% 11
8 IMUNOBIOFOTON 37236 0% 63% 5
9 ROCKY MT POISON DRUG 32970 1% 15% 18
10 HAMNER 31775 0% 67% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL TOXICOLOGY 25058 2% 4% 56
2 TOXICOLOGY AND APPLIED PHARMACOLOGY 17642 5% 1% 121
3 BIOCHEMICAL PHARMACOLOGY 6974 4% 1% 105
4 DRUG METABOLISM AND DISPOSITION 5437 2% 1% 59
5 TOXICOLOGICAL SCIENCES 5324 2% 1% 47
6 DRUG METABOLISM REVIEWS 4756 1% 2% 20
7 TOXICOLOGY 4196 2% 1% 50
8 HEPATOLOGY 3893 2% 1% 63
9 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 3594 3% 0% 81
10 CHEMICAL RESEARCH IN TOXICOLOGY 3422 2% 1% 39

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ACETAMINOPHEN 2240921 28% 26% 711 Search ACETAMINOPHEN Search ACETAMINOPHEN
2 PARACETAMOL 300762 9% 11% 229 Search PARACETAMOL Search PARACETAMOL
3 HEPATOTOXICITY 242142 11% 7% 275 Search HEPATOTOXICITY Search HEPATOTOXICITY
4 ACETAMINOPHEN HEPATOTOXICITY 202118 1% 81% 21 Search ACETAMINOPHEN+HEPATOTOXICITY Search ACETAMINOPHEN+HEPATOTOXICITY
5 ACETAMINOPHEN APAP 111878 1% 72% 13 Search ACETAMINOPHEN+APAP Search ACETAMINOPHEN+APAP
6 PARACETAMOL POISONING 108332 0% 91% 10 Search PARACETAMOL+POISONING Search PARACETAMOL+POISONING
7 ACETAMINOPHEN TOXICITY 107529 1% 48% 19 Search ACETAMINOPHEN+TOXICITY Search ACETAMINOPHEN+TOXICITY
8 ACETAMINOPHEN OVERDOSE 107245 0% 75% 12 Search ACETAMINOPHEN+OVERDOSE Search ACETAMINOPHEN+OVERDOSE
9 NAPQI 99303 0% 83% 10 Search NAPQI Search NAPQI
10 ACETYLCYSTEINE 76173 1% 17% 37 Search ACETYLCYSTEINE Search ACETYLCYSTEINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BESSEMS, JGM , VERMEULEN, NPE , (2001) PARACETAMOL (ACETAMINOPHEN)-INDUCED TOXICITY: MOLECULAR AND BIOCHEMICAL MECHANISMS, ANALOGUES AND PROTECTIVE APPROACHES.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 31. ISSUE 1. P. 55 -138 260 71% 322
2 MCGILL, MR , JAESCHKE, H , (2013) METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS.PHARMACEUTICAL RESEARCH. VOL. 30. ISSUE 9. P. 2174-2187 110 66% 72
3 PRESCOTT, LF , (2000) PARACETAMOL, ALCOHOL AND THE LIVER.BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 49. ISSUE 4. P. 291 -301 106 88% 84
4 JAESCHKE, H , MCGILL, MR , WILLIAMS, CD , RAMACHANDRAN, A , (2011) CURRENT ISSUES WITH ACETAMINOPHEN HEPATOTOXICITY-A CLINICALLY RELEVANT MODEL TO TEST THE EFFICACY OF NATURAL PRODUCTS.LIFE SCIENCES. VOL. 88. ISSUE 17-18. P. 737-745 78 79% 71
5 JAESCHKE, H , WILLIAMS, CD , MCGILL, MR , XIE, YC , RAMACHANDRAN, A , (2013) MODELS OF DRUG-INDUCED LIVER INJURY FOR EVALUATION OF PHYTOTHERAPEUTICS AND OTHER NATURAL PRODUCTS.FOOD AND CHEMICAL TOXICOLOGY. VOL. 55. ISSUE . P. 279-289 89 64% 26
6 BUNCHORNTAVAKUL, C , REDDY, KR , (2013) ACETAMINOPHEN-RELATED HEPATOTOXICITY.CLINICS IN LIVER DISEASE. VOL. 17. ISSUE 4. P. 587 -+ 74 70% 36
7 ZYOUD, SH , WARING, WS , AL-JABI, SW , SWEILEH, WM , AWANG, R , (2016) THE 100 MOST INFLUENTIAL PUBLICATIONS IN PARACETAMOL POISONING TREATMENT: A BIBLIOMETRIC ANALYSIS OF HUMAN STUDIES.SPRINGERPLUS. VOL. 5. ISSUE . P. - 82 69% 0
8 JAESCHKE, H , WILLIAMS, CD , RAMACHANDRAN, A , BAJT, ML , (2012) ACETAMINOPHEN HEPATOTOXICITY AND REPAIR: THE ROLE OF STERILE INFLAMMATION AND INNATE IMMUNITY.LIVER INTERNATIONAL. VOL. 32. ISSUE 1. P. 8 -20 71 64% 90
9 HODGMAN, MJ , GARRARD, AR , (2012) A REVIEW OF ACETAMINOPHEN POISONING.CRITICAL CARE CLINICS. VOL. 28. ISSUE 4. P. 499-+ 70 77% 32
10 JAESCHKE, H , BAJT, ML , (2006) INTRACELLULAR SIGNALING MECHANISMS OF ACETAMINOPHEN-INDUCED LIVER CELL DEATH.TOXICOLOGICAL SCIENCES. VOL. 89. ISSUE 1. P. 31-41 71 66% 275

Classes with closest relation at Level 1


Rank Class id link
1 17600 INTRAVENOUS ACETAMINOPHEN//PARACETAMOL//PROPACETAMOL
2 3896 ACUTE LIVER FAILURE//ALBUMIN DIALYSIS//ACUTE ON CHRONIC LIVER FAILURE
3 15943 TRICHLOROMETHYLPEROXYL//TRICHLOROMETHYL//CELL SURFACE BLEBS
4 25846 IDIOSYNCRATIC DRUG INDUCED LIVER INJURY//PHAGOCYTOSIS BLOCKADE//ALPHA NAPHTHYLISOTHIOCYANATE
5 23311 SUCCINIMIDES//N 3 5 DICHLOROPHENYLSUCCINIMIDE//SPLENIC TOXICITY
6 10357 CHLORZOXAZONE//CYP2E1//6 HYDROXYCHLORZOXAZONE
7 5104 DRUG INDUCED LIVER INJURY//HEPATOTOXICITY//HERB INDUCED LIVER INJURY
8 14974 MITOCHONDRIAL APOPTOSIS SIGNALING//APOPTOSIS IN UNDIFFERENTIATED CELLS//GSH COMPARTMENTATION
9 6473 POISONING//POISON CONTROL CENTERS//POISON CENTER
10 36229 PREMNA TOMENTOSA//PREMNA LATIFOLIA//ICETEXANE DITERPENES

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