Class information for:
Level 1: SUCCINIMIDES//N 3 5 DICHLOROPHENYLSUCCINIMIDE//SPLENIC TOXICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23311 350 29.2 52%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
1239 2             HETEROCYCLIC AMINES//HETEROCYCLIC AROMATIC AMINES//PHIP 9032
23311 1                   SUCCINIMIDES//N 3 5 DICHLOROPHENYLSUCCINIMIDE//SPLENIC TOXICITY 350

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SUCCINIMIDES authKW 471088 5% 30% 18
2 N 3 5 DICHLOROPHENYLSUCCINIMIDE authKW 348973 1% 100% 4
3 SPLENIC TOXICITY authKW 261730 1% 100% 3
4 2 5 DIFLUORONITROBENZENE authKW 174486 1% 100% 2
5 MDA PROTEIN ADDUCTS authKW 174486 1% 100% 2
6 HALOGENATED HYDROCARBONS authKW 147386 4% 12% 14
7 PARA AMINOPHENOL authKW 128292 1% 29% 5
8 FUSED SILICA OPEN TUBULAR COLUMN authKW 116323 1% 67% 2
9 HINDLIMB PARALYSIS authKW 116323 1% 67% 2
10 PARA CHLORONITROBENZENE authKW 116319 1% 33% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 17541 66% 0% 232
2 Pharmacology & Pharmacy 1798 42% 0% 148
3 Environmental Sciences 82 9% 0% 32
4 Public, Environmental & Occupational Health 64 7% 0% 24
5 Chemistry, Medicinal 58 5% 0% 16
6 Thermodynamics 21 3% 0% 9
7 Chemistry, Analytical 14 4% 0% 15
8 Chemistry, Multidisciplinary 11 7% 0% 24
9 Genetics & Heredity 10 4% 0% 13
10 Engineering, Chemical 2 3% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENVIRONM LIFE TOXICOL 87243 0% 100% 1
2 JIOAN C EDWARDS MED 87243 0% 100% 1
3 METAB PHARMACOKINET SECT 87243 0% 100% 1
4 NEUROSCI COIMBRA ZOOL 87243 0% 100% 1
5 SANIT MICROORGANISMS 87243 0% 100% 1
6 SERV MED INTERENTREPRISE 87243 0% 100% 1
7 SERV PHARMACOCINET TOXICOL CLIN 87243 0% 100% 1
8 BURNS WOUND CARE 43621 0% 50% 1
9 ROBERT C BYRD BIOTECHNOL SCI 39254 1% 15% 3
10 TOXICOL PHARMACOCINET CLIN 38772 1% 22% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOLOGY 45157 17% 1% 60
2 XENOBIOTICA 10896 6% 1% 22
3 FUNDAMENTAL AND APPLIED TOXICOLOGY 4986 3% 1% 11
4 JOURNAL OF APPLIED TOXICOLOGY 4457 3% 0% 12
5 TOXICOLOGY AND APPLIED PHARMACOLOGY 3190 5% 0% 19
6 TOXICOLOGY LETTERS 3006 5% 0% 17
7 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES 2808 3% 0% 9
8 DRUG METABOLISM AND DISPOSITION 2261 4% 0% 14
9 ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS-PART C OF JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH 1340 0% 2% 1
10 BIOMARKERS 1102 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SUCCINIMIDES 471088 5% 30% 18 Search SUCCINIMIDES Search SUCCINIMIDES
2 N 3 5 DICHLOROPHENYLSUCCINIMIDE 348973 1% 100% 4 Search N+3+5+DICHLOROPHENYLSUCCINIMIDE Search N+3+5+DICHLOROPHENYLSUCCINIMIDE
3 SPLENIC TOXICITY 261730 1% 100% 3 Search SPLENIC+TOXICITY Search SPLENIC+TOXICITY
4 2 5 DIFLUORONITROBENZENE 174486 1% 100% 2 Search 2+5+DIFLUORONITROBENZENE Search 2+5+DIFLUORONITROBENZENE
5 MDA PROTEIN ADDUCTS 174486 1% 100% 2 Search MDA+PROTEIN+ADDUCTS Search MDA+PROTEIN+ADDUCTS
6 HALOGENATED HYDROCARBONS 147386 4% 12% 14 Search HALOGENATED+HYDROCARBONS Search HALOGENATED+HYDROCARBONS
7 PARA AMINOPHENOL 128292 1% 29% 5 Search PARA+AMINOPHENOL Search PARA+AMINOPHENOL
8 FUSED SILICA OPEN TUBULAR COLUMN 116323 1% 67% 2 Search FUSED+SILICA+OPEN+TUBULAR+COLUMN Search FUSED+SILICA+OPEN+TUBULAR+COLUMN
9 HINDLIMB PARALYSIS 116323 1% 67% 2 Search HINDLIMB+PARALYSIS Search HINDLIMB+PARALYSIS
10 PARA CHLORONITROBENZENE 116319 1% 33% 4 Search PARA+CHLORONITROBENZENE Search PARA+CHLORONITROBENZENE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RANKIN, GO , (2004) NEPHROTOXICITY INDUCED BY C- AND N-ARYLSUCCINIMIDES.JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS. VOL. 7. ISSUE 5. P. 399-416 43 64% 9
2 CUI, DH , RANKIN, GO , HARVISON, PJ , (2005) METABOLISM OF THE NEPHROTOXICANT N-(3,5-DICHLOROPHENYL)SUCCINIMIDE IN RATS: EVIDENCE FOR BIOACTIVATION THROUGH ALCOHOL-O-GLUCURONIDATION AND O-SULFATION.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 18. ISSUE 6. P. 991-1003 29 83% 8
3 RANKIN, GO , HONG, SK , ANESTIS, DK , (2008) NEPHROTOXICITY INDUCED BY N-(3,5-DICHLOROPHENYL)-3-HYDROXYSUCCINAMIC ACID IN MALE AND FEMALE FISCHER 344 RATS.JOURNAL OF APPLIED TOXICOLOGY. VOL. 28. ISSUE 7. P. 867 -873 24 89% 1
4 RANKIN, GO , SWEENEY, A , RACINE, C , FERGUSON, T , PRESTON, D , ANESTIS, DK , (2014) 4-AMINO-2-CHLOROPHENOL: COMPARATIVE IN VITRO NEPHROTOXICITY AND MECHANISMS OF BIOACTIVATION.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 222. ISSUE . P. 126 -132 28 61% 1
5 RACINE, CR , FERGUSON, T , PRESTON, D , WARD, D , BALL, J , ANESTIS, D , VALENTOVIC, M , RANKIN, GO , (2016) THE ROLE OF BIOTRANSFORMATION AND OXIDATIVE STRESS IN 3,5-DICHLOROANILINE (3,5-DCA) INDUCED NEPHROTOXICITY IN ISOLATED RENAL CORTICAL CELLS FROM MALE FISCHER 344 RATS.TOXICOLOGY. VOL. 341. ISSUE . P. 47 -55 32 51% 0
6 RANKIN, GO , ANESTIS, DK , VALENTOVIC, MA , SUN, H , TRIEST, WE , (2007) NEPHROTOXICITY INDUCED BY THE R- AND S-ENANTIOMERS OF N-(3,5-DICHLOROPHENYL)-2-HYDROXYSUCCINIMIDE (NDHS) AND THEIR SULFATE CONJUGATES IN MALE FISCHER 344 RATS.TOXICOLOGY. VOL. 240. ISSUE 1-2. P. 38-47 25 64% 2
7 HONG, SK , ANESTIS, DK , VALENTOVIC, MA , BALL, JG , BROWN, PI , RANKIN, GO , (2001) GENDER DIFFERENCES IN THE POTENTIATION OF N-(3,5-DICHLOROPHENYL)SUCCINIMIDE METABOLITE NEPHROTOXICITY BY PHENOBARBITAL.JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES. VOL. 64. ISSUE 3. P. 241 -256 26 68% 7
8 HENESEY, CM , KELLNER-WEIBEL, GL , TARLOFF, JB , HARVISON, PJ , (1999) COMPARATIVE DISPOSITION OF THE NEPHROTOXICANT N-(3,5-DICHLOROPHENYL)SUCCINIMIDE AND THE NON-NEPHROTOXICANT N-(3,5-DIFLUOROPHENYL)SUCCINIMIDE IN FISCHER 344 RATS.DRUG METABOLISM AND DISPOSITION. VOL. 27. ISSUE 6. P. 674-680 22 85% 5
9 RANKIN, GO , HONG, SK , ANESTIS, DK , LASH, LH , MILES, SL , (2001) IN VITRO NEPHROTOXICITY INDUCED BY N-(3,5-DICHLOROPHENYL)SUCCINIMIDE (NDPS) METABOLITES IN ISOLATED RENAL CORTICAL CELLS FROM MALE AND FEMALE FISCHER 344 RATS: EVIDENCE FOR A NEPHROTOXIC SULFATE CONJUGATE METABOLITE.TOXICOLOGY. VOL. 163. ISSUE 2-3. P. 73 -82 21 81% 8
10 HONG, SK , ANESTIS, DK , BALL, JG , VALENTOVIC, MA , BROWN, PI , RANKIN, GO , (1999) SODIUM SULFATE POTENTIATES N-(3,5-DICHLOROPHENYL)-2-HYDROXYSUCCINIMIDE (NDHS) AND N-(3,5-DICHLOROPHENYL)-2-HYDROXYSUCCINAMIC ACID (2-NDHSA) NEPHROTOXICITY IN THE FISCHER 344 RAT.TOXICOLOGY. VOL. 138. ISSUE 3. P. 165-174 19 86% 3

Classes with closest relation at Level 1


Rank Class id link
1 30871 PROPANIL//PCT ABS//POLYCHLORINATED AZOBENZENES
2 32060 CEPHALORIDINE//PHARMACEUT SCI TOXICOL CLIN PHARMACOL//AHMANSON ELE ON MICROSCOPY ADV IMAGING
3 20043 1 3 DINITROBENZENE//DINITROBENZENE//REPRODUCTIVE SCREEN
4 22423 PARADICHLOROBENZENE//MOTHBALLS//BROMOBENZENE
5 13167 FLORIDA TOXICOL//3 3 DICHLOROBENZIDINE//N 2 METHOXYPHENYLHYDROXYLAMINE
6 18798 HAIR DYE//PARA PHENYLENEDIAMINE//OXIDATION HAIR DYE
7 29510 MOVEMENT ACTIVITY//PIPERONYL BUTOXIDE//ENZYMATICALLY MODIFIED ISOQUERCITRIN
8 6136 TRICHLOROETHYLENE//S 1 2 DICHLOROVINYL L CYSTEINE//TRICHLOROACETATE
9 11215 METHEMOGLOBINEMIA//DAPSONE//ISOBUTYL NITRITE
10 1628 ACETAMINOPHEN//PARACETAMOL//HEPATOTOXICITY

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