Class information for:
Level 1: HEXOKINASE//HEXOKINASE II//BRAIN HEXOKINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15197 726 37.4 57%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
3350 2             VDAC//VOLTAGE DEPENDENT ANION CHANNEL//HEXOKINASE 1718
15197 1                   HEXOKINASE//HEXOKINASE II//BRAIN HEXOKINASE 726

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEXOKINASE authKW 631593 15% 14% 106
2 HEXOKINASE II authKW 202413 3% 25% 19
3 BRAIN HEXOKINASE authKW 168233 1% 100% 4
4 HEXOKINASE TYPE I authKW 168233 1% 100% 4
5 HEXOKINASE 2 authKW 164849 2% 28% 14
6 HEXOKINASE MAMMALIAN ISOZYMES OF authKW 126175 0% 100% 3
7 TYPE II HEXOKINASE authKW 112153 1% 67% 4
8 HEXOKINASE BINDING authKW 84117 0% 100% 2
9 HEXOKINASE DEFICIENCY authKW 84117 0% 100% 2
10 HEXOKINASE MAMMALIAN EVOLUTION OF authKW 84117 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 3569 58% 0% 418
2 Biophysics 3092 24% 0% 175
3 Cell Biology 485 15% 0% 108
4 Oncology 108 8% 0% 61
5 Hematology 79 4% 0% 29
6 Physiology 40 4% 0% 26
7 Endocrinology & Metabolism 25 4% 0% 26
8 Medicine, Research & Experimental 22 3% 0% 24
9 Genetics & Heredity 15 3% 0% 25
10 Biochemical Research Methods 11 2% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MICRO PET 84117 0% 100% 2
2 AREA NEUROGENET 42058 0% 100% 1
3 CARDIOVASCUL SCI 42058 0% 100% 1
4 CONFOCAL FLUO CENCE MICROSCOPY 42058 0% 100% 1
5 CYTOPATHOL ABT 42058 0% 100% 1
6 ENDOCRINOL PHARMACOL METAB UNIT 42058 0% 100% 1
7 INTERNAL MED PULM MED INFECT DIS 42058 0% 100% 1
8 IST CHIM BIOL G FORMAINI 42058 0% 100% 1
9 NAST NANOSCI 42058 0% 100% 1
10 PROGRAMA BIOFIS BIOQUIM CEULAR 42058 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 12806 10% 0% 72
2 ITALIAN JOURNAL OF BIOCHEMISTRY 4455 1% 2% 6
3 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 2652 2% 1% 11
4 BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY 2189 1% 1% 6
5 MOLECULAR AND CELLULAR BIOCHEMISTRY 1959 3% 0% 21
6 BIOCHIMICA ET BIOPHYSICA ACTA 1751 5% 0% 35
7 BULLETIN OF MOLECULAR BIOLOGY AND MEDICINE 1242 0% 1% 2
8 PREPARATIVE BIOCHEMISTRY 911 0% 1% 3
9 BIOCHEMISTRY INTERNATIONAL 817 1% 0% 8
10 METHODS OF BIOCHEMICAL ANALYSIS 777 0% 2% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HEXOKINASE 631593 15% 14% 106 Search HEXOKINASE Search HEXOKINASE
2 HEXOKINASE II 202413 3% 25% 19 Search HEXOKINASE+II Search HEXOKINASE+II
3 BRAIN HEXOKINASE 168233 1% 100% 4 Search BRAIN+HEXOKINASE Search BRAIN+HEXOKINASE
4 HEXOKINASE TYPE I 168233 1% 100% 4 Search HEXOKINASE+TYPE+I Search HEXOKINASE+TYPE+I
5 HEXOKINASE 2 164849 2% 28% 14 Search HEXOKINASE+2 Search HEXOKINASE+2
6 HEXOKINASE MAMMALIAN ISOZYMES OF 126175 0% 100% 3 Search HEXOKINASE+MAMMALIAN+ISOZYMES+OF Search HEXOKINASE+MAMMALIAN+ISOZYMES+OF
7 TYPE II HEXOKINASE 112153 1% 67% 4 Search TYPE+II+HEXOKINASE Search TYPE+II+HEXOKINASE
8 HEXOKINASE BINDING 84117 0% 100% 2 Search HEXOKINASE+BINDING Search HEXOKINASE+BINDING
9 HEXOKINASE DEFICIENCY 84117 0% 100% 2 Search HEXOKINASE+DEFICIENCY Search HEXOKINASE+DEFICIENCY
10 HEXOKINASE MAMMALIAN EVOLUTION OF 84117 0% 100% 2 Search HEXOKINASE+MAMMALIAN+EVOLUTION+OF Search HEXOKINASE+MAMMALIAN+EVOLUTION+OF

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WILSON, JE , (1995) HEXOKINASES.REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, VOL 126. VOL. 126. ISSUE . P. 65-198 150 42% 260
2 WILSON, JE , (2003) ISOZYMES OF MAMMALIAN HEXOKINASE: STRUCTURE, SUBCELLULAR LOCALIZATION AND METABOLIC FUNCTION.JOURNAL OF EXPERIMENTAL BIOLOGY. VOL. 206. ISSUE 12. P. 2049-2057 38 86% 374
3 ROBERTS, DJ , MIYAMOTO, S , (2015) HEXOKINASE II INTEGRATES ENERGY METABOLISM AND CELLULAR PROTECTION: AKTING ON MITOCHONDRIA AND TORCING TO AUTOPHAGY.CELL DEATH AND DIFFERENTIATION. VOL. 22. ISSUE 2. P. 248 -257 66 40% 22
4 ROBEY, RB , HAY, N , (2006) MITOCHONDRIAL HEXOKINASES, NOVEL MEDIATORS OF THE ANTIAPOPTOTIC EFFECTS OF GROWTH FACTORS AND AKT.ONCOGENE. VOL. 25. ISSUE 34. P. 4683-4696 59 48% 223
5 SUN, L , SHUKAIR, S , NAIK, TJ , MOAZED, F , ARDEHALI, H , (2008) GLUCOSE PHOSPHORYLATION AND MITOCHONDRIAL BINDING ARE REQUIRED FOR THE PROTECTIVE EFFECTS OF HEXOKINASES I AND II.MOLECULAR AND CELLULAR BIOLOGY. VOL. 28. ISSUE 3. P. 1007-1017 37 67% 101
6 WYATT, E , WU, RX , RABEH, W , PARK, HW , GHANEFAR, M , ARDEHALI, H , (2010) REGULATION AND CYTOPROTECTIVE ROLE OF HEXOKINASE III.PLOS ONE. VOL. 5. ISSUE 11. P. - 34 77% 17
7 PEDERSEN, PL , MATHUPALA, S , REMPEL, A , GESCHWIND, JF , KO, YH , (2002) MITOCHONDRIAL BOUND TYPE II HEXOKINASE: A KEY PLAYER IN THE GROWTH AND SURVIVAL OF MANY CANCERS AND AN IDEAL PROSPECT FOR THERAPEUTIC INTERVENTION.BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. VOL. 1555. ISSUE 1-3. P. 14-20 39 61% 197
8 MATHUPALA, SP , KO, YH , PEDERSEN, PL , (2009) HEXOKINASE-2 BOUND TO MITOCHONDRIA: CANCER'S STYGIAN LINK TO THE "WARBURG EFFECT" AND A PIVOTAL TARGET FOR EFFECTIVE THERAPY.SEMINARS IN CANCER BIOLOGY. VOL. 19. ISSUE 1. P. 17-24 30 54% 196
9 MATHUPALA, SP , KO, YH , PEDERSEN, PL , (2006) HEXOKINASE II: CANCER'S DOUBLE-EDGED SWORD ACTING AS BOTH FACILITATOR AND GATEKEEPER OF MALIGNANCY WHEN BOUND TO MITOCHONDRIA.ONCOGENE. VOL. 25. ISSUE 34. P. 4777-4786 37 46% 296
10 HASHIMOTO, M , WILSON, JE , (2002) KINETIC AND REGULATORY PROPERTIES OF HKI+, A MODIFIED FORM OF THE TYPE I ISOZYME OF MAMMALIAN HEXOKINASE IN WHICH INTERACTIONS BETWEEN THE N- AND C-TERMINAL HALVES HAVE BEEN DISRUPTED.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 399. ISSUE 1. P. 109 -115 29 97% 4

Classes with closest relation at Level 1


Rank Class id link
1 14922 VDAC//VOLTAGE DEPENDENT ANION CHANNEL//MITOCHONDRIAL PORIN
2 10494 GLUCOKINASE//GLUCOKINASE ACTIVATOR//GLUCOKINASE REGULATORY PROTEIN
3 24828 ECOM//FARMACOS//ONCOBIOL MOL OMOL
4 4289 3 BROMOPYRUVATE//WARBURG EFFECT//CANCER METABOLISM
5 30643 GLYCEROL KINASE DEFICIENCY//COMPLEX GLYCEROL KINASE DEFICIENCY//KOHLSCHUTTER TONZ SYNDROME
6 8765 PKM2//PYRUVATE KINASE//PYRUVATE KINASE DEFICIENCY
7 35343 NIF3//THIOPENTAL COMA//ACTIVITY BRAIN
8 36100 SALICYLIDENEAMINO 2 THIOPHENOL//ALPHA AMINOPHENYL CEPHALOPSORINS//APO 27 MONOCLONAL ANTIBODY
9 20226 RIBOKINASE//ADENOSINE KINASE//D GLUCOSE DEHYDROGENASE
10 24339 LONIDAMINE//IONIDAMINE//ADVANCED BREAST CANCER CHEMOTHERAPY

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