Class information for:
Level 1: LONIDAMINE//IONIDAMINE//ADVANCED BREAST CANCER CHEMOTHERAPY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24339 315 30.9 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
1816 2             INTERNATIONAL JOURNAL OF HYPERTHERMIA//HYPERTHERMIA//ISOLATED LIMB PERFUSION 6226
24339 1                   LONIDAMINE//IONIDAMINE//ADVANCED BREAST CANCER CHEMOTHERAPY 315

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LONIDAMINE authKW 7537825 31% 80% 97
2 IONIDAMINE authKW 258496 1% 67% 4
3 ADVANCED BREAST CANCER CHEMOTHERAPY authKW 193874 1% 100% 2
4 ANTISPERMATOGENIC DRUGS authKW 193874 1% 100% 2
5 LONIDAMINE AND BREAST CANCER authKW 193874 1% 100% 2
6 LONIDAMINE THERAPY authKW 193874 1% 100% 2
7 MALE PUBERTAL MICE authKW 193874 1% 100% 2
8 MITOMYCIN C DRUG COMBINATION authKW 193874 1% 100% 2
9 PENN SUPERFUND TRAINING PROGRAM address 193874 1% 100% 2
10 TOLNIDAMINE authKW 193874 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 4964 64% 0% 202
2 Pharmacology & Pharmacy 157 15% 0% 48
3 Pathology 77 5% 0% 16
4 CYTOLOGY & HISTOLOGY 48 1% 0% 2
5 Radiology, Nuclear Medicine & Medical Imaging 30 5% 0% 16
6 Microscopy 7 1% 0% 2
7 Biophysics 7 3% 0% 9
8 Reproductive Biology 7 1% 0% 4
9 Obstetrics & Gynecology 7 2% 0% 7
10 Andrology 6 0% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PENN SUPERFUND TRAINING PROGRAM 193874 1% 100% 2
2 DIPARTIMENTO MED SPERIMENTALE SANITA PUBBLICA 96937 0% 100% 1
3 EXCELLENCE ENVIRONM TOXICOL MED 96937 0% 100% 1
4 INVEST BIOENERGET CIBIERG 96937 0% 100% 1
5 IST CLIN MED IV 96937 0% 100% 1
6 IST ISTOL EMBRIOL LARGO FRANCESCO VITO 1 96937 0% 100% 1
7 ULTRASTRUCT VIALE REGINA ELENA 299 96937 0% 100% 1
8 INTERDISCIPLINARY MALE CONTRACEPT DRUG 64622 1% 33% 2
9 ASL6 48468 0% 50% 1
10 HUMAN BIOPATHOL HAEMATOL 48468 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOLOGY 11928 7% 1% 22
2 EXPERIMENTAL AND MOLECULAR PATHOLOGY 7120 4% 1% 14
3 CHEMOTHERAPY 3812 3% 0% 10
4 TUMORI 3495 4% 0% 13
5 ANTICANCER RESEARCH 3156 8% 0% 25
6 SEMINARS IN ONCOLOGY 3134 4% 0% 13
7 INTERNATIONAL JOURNAL OF ONCOLOGY 2590 5% 0% 16
8 ONCOLOGY RESEARCH 1287 1% 0% 4
9 INTERNATIONAL JOURNAL OF HYPERTHERMIA 1242 2% 0% 5
10 CANCER BIOTHERAPY 1018 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LONIDAMINE 7537825 31% 80% 97 Search LONIDAMINE Search LONIDAMINE
2 IONIDAMINE 258496 1% 67% 4 Search IONIDAMINE Search IONIDAMINE
3 ADVANCED BREAST CANCER CHEMOTHERAPY 193874 1% 100% 2 Search ADVANCED+BREAST+CANCER+CHEMOTHERAPY Search ADVANCED+BREAST+CANCER+CHEMOTHERAPY
4 ANTISPERMATOGENIC DRUGS 193874 1% 100% 2 Search ANTISPERMATOGENIC+DRUGS Search ANTISPERMATOGENIC+DRUGS
5 LONIDAMINE AND BREAST CANCER 193874 1% 100% 2 Search LONIDAMINE+AND+BREAST+CANCER Search LONIDAMINE+AND+BREAST+CANCER
6 LONIDAMINE THERAPY 193874 1% 100% 2 Search LONIDAMINE+THERAPY Search LONIDAMINE+THERAPY
7 MALE PUBERTAL MICE 193874 1% 100% 2 Search MALE+PUBERTAL+MICE Search MALE+PUBERTAL+MICE
8 MITOMYCIN C DRUG COMBINATION 193874 1% 100% 2 Search MITOMYCIN+C+DRUG+COMBINATION Search MITOMYCIN+C+DRUG+COMBINATION
9 TOLNIDAMINE 193874 1% 100% 2 Search TOLNIDAMINE Search TOLNIDAMINE
10 TUMOR DE ENERGIZATION 193874 1% 100% 2 Search TUMOR+DE+ENERGIZATION Search TUMOR+DE+ENERGIZATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DI COSIMO, S , FERRETTI, G , PAPALDO, P , CARLINI, P , FABI, A , COGNETTI, F , (2003) LONIDAMINE: EFFICACY AND SAFETY IN CLINICAL TRIALS FOR THE TREATMENT OF SOLID TUMORS.DRUGS OF TODAY. VOL. 39. ISSUE 3. P. 157-173 43 90% 72
2 NATH, K , GUO, LL , NANCOLAS, B , NELSON, DS , SHESTOV, AA , LEE, SC , ROMAN, J , ZHOU, R , LEEPER, DB , HALESTRAP, AP , ET AL (2016) MECHANISM OF ANTINEOPLASTIC ACTIVITY OF LONIDAMINE.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1866. ISSUE 2. P. 151 -162 44 53% 0
3 PRICE, GS , CLINE, JM , PAGE, RL , RIVIERE, JE , THRALL, DE , (1998) POTENTIAL COMPLICATIONS ASSOCIATED WITH NORMOTHERMIC LONIDAMINE INFUSION AND WITH SYSTEMIC ACIDOSIS IN DOGS RECEIVING LONIDAMINE DURING WHOLE BODY HYPERTHERMIA (WBH).INTERNATIONAL JOURNAL OF HYPERTHERMIA. VOL. 14. ISSUE 3. P. 271-283 36 88% 0
4 PRICE, GS , PAGE, RL , RIVIERE, JE , CLINE, JM , THRALL, DE , (1996) PHARMACOKINETICS AND TOXICITY OF ORAL AND INTRAVENOUS LONIDAMINE IN DOGS.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 38. ISSUE 2. P. 129-135 28 93% 20
5 TEICHER, BA , (1994) LONIDAMINE - IN-VITRO IN-VIVO CORRELATIONS.EUROPEAN JOURNAL OF CANCER. VOL. 30A. ISSUE 10. P. 1411-1413 29 97% 15
6 DELENA, M , LORUSSO, V , BOTTALICO, C , BRANDI, M , DEMITRIO, A , CATINO, A , GUIDA, M , LATORRE, A , LEONE, B , VALLEJO, C , ET AL (1997) REVERTANT AND POTENTIATING ACTIVITY OF LONIDAMINE IN PATIENTS WITH OVARIAN CANCER PREVIOUSLY TREATED WITH PLATINUM.JOURNAL OF CLINICAL ONCOLOGY. VOL. 15. ISSUE 10. P. 3208-3213 26 87% 18
7 CERVANTES-MADRID, D , ROMERO, Y , DUENAS-GONZALEZ, A , (2015) REVIVING LONIDAMINE AND 6-DIAZO-5-OXO-L-NORLEUCINE TO BE USED IN COMBINATION FOR METABOLIC CANCER THERAPY.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 36 36% 4
8 FRASSINETI, GL , NANNI, O , MILANDRI, C , FERRARI, M , DEMATTEIS, A , MUSTACCHI, G , CARIELLO, S , MASCIA, V , SANTORO, A , AMADORI, D , ET AL (1994) LONIDAMINE IN MODULATION OF RESPONSE TO ADRIAMYCIN IN ADVANCED BREAST-CANCER - PRELIMINARY-RESULTS.INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 4. ISSUE . P. 741-746 25 100% 1
9 SILVESTRINI, R , GORNATI, D , ZAFFARONI, N , BEARZATTO, A , DEMARCO, C , (1997) MODULATION BY LONIDAMINE ON THE COMBINED ACTIVITY OF CISPLATIN AND EPIDOXORUBICIN IN HUMAN BREAST CANCER CELLS.BREAST CANCER RESEARCH AND TREATMENT. VOL. 42. ISSUE 2. P. 103-112 21 100% 5
10 MORAGLIO, L , BREMA, F , PASTORINO, G , MARTINI, MC , VALLAURI, M , (1995) COMBINATION OF EPIRUBICIN AND LONIDAMINE FOR TREATMENT OF ADVANCED BREAST-CANCER.TUMORI. VOL. 81. ISSUE 2. P. 107-111 24 92% 5

Classes with closest relation at Level 1


Rank Class id link
1 25798 2 DEOXY D GLUCOSE//CELL BIOL R 124//METABOLIC OXIDATIVE STRESS
2 31256 DIACEREIN//DIACERHEIN//DIACETYLRHEIN
3 16621 PHLIP//TUMOR ACIDITY//TUMOR PH
4 16760 WHOLE BODY HYPERTHERMIA//INTERNATIONAL JOURNAL OF HYPERTHERMIA//HYPERTHERMIA
5 20591 INDAZOLE//2H INDAZOLES//INDAZOLONE
6 36891 GLUTATHIONE DOXORUBICIN CONJUGATE//RAT HEPATOMA CELL//EXPT CYTOL
7 4289 3 BROMOPYRUVATE//WARBURG EFFECT//CANCER METABOLISM
8 15197 HEXOKINASE//HEXOKINASE II//BRAIN HEXOKINASE
9 2869 SERTOLI CELLS//BLOOD TESTIS BARRIER//MARY M WOHLFORD MALE CONTRACEPT
10 11789 INTERNATIONAL JOURNAL OF HYPERTHERMIA//STEP DOWN HEATING//HYPERTHERMIA

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