Class information for:
Level 1: 3 BROMOPYRUVATE//WARBURG EFFECT//CANCER METABOLISM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4289 1811 55.7 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
2612 2             WARBURG EFFECT//PKM2//PYRUVATE KINASE 3575
4289 1                   3 BROMOPYRUVATE//WARBURG EFFECT//CANCER METABOLISM 1811

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 3 BROMOPYRUVATE authKW 721038 3% 70% 61
2 WARBURG EFFECT authKW 714742 8% 28% 153
3 CANCER METABOLISM authKW 336841 4% 26% 76
4 DICHLOROACETATE authKW 263349 3% 25% 63
5 GLUTAMINOLYSIS authKW 239782 2% 34% 42
6 GLYCOLYSIS authKW 227421 12% 6% 214
7 TIGAR authKW 226647 1% 61% 22
8 TUMOR METABOLISM authKW 149027 2% 23% 39
9 AEROBIC GLYCOLYSIS authKW 138232 2% 19% 44
10 LACTATE DEHYDROGENASE A authKW 130790 1% 52% 15

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 12758 44% 0% 791
2 Cell Biology 7000 32% 0% 588
3 Biochemistry & Molecular Biology 1595 28% 0% 499
4 Biophysics 279 6% 0% 101
5 Medicine, Research & Experimental 234 5% 0% 98
6 Genetics & Heredity 150 5% 0% 95
7 Chemistry, Medicinal 94 3% 0% 53
8 Endocrinology & Metabolism 76 4% 0% 69
9 Pathology 50 2% 0% 40
10 Pharmacology & Pharmacy 30 5% 0% 95

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WINSHIP CANC EMORY 71926 0% 53% 8
2 SYST BIOL HUMAN DIS 67433 0% 67% 6
3 REGULATORY ENVIRONM ANALYT METABOL 56184 1% 33% 10
4 GASTROINTESTINAL GLAND SURG 46827 0% 56% 5
5 SYSBIO SYST BIOL 35118 0% 42% 5
6 FIELD GENOM GENET DEV 33719 0% 100% 2
7 OMICS CORE 33719 0% 100% 2
8 PL RADIAT ONCOL 33719 0% 100% 2
9 PROT GENE BIOMARKERS UNIT 33719 0% 100% 2
10 UM BIOPK 33719 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOTARGET 13104 5% 1% 98
2 CELL METABOLISM 11819 2% 2% 32
3 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 6405 1% 1% 27
4 CANCER CELL 4831 1% 1% 21
5 NATURE REVIEWS CANCER 3066 1% 1% 14
6 MOLECULAR CANCER 2414 1% 1% 16
7 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 2237 1% 1% 10
8 CELL DEATH & DISEASE 2037 1% 1% 17
9 MOLECULAR CELL 1595 1% 0% 23
10 CELL REPORTS 1464 1% 1% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 3 BROMOPYRUVATE 721038 3% 70% 61 Search 3+BROMOPYRUVATE Search 3+BROMOPYRUVATE
2 WARBURG EFFECT 714742 8% 28% 153 Search WARBURG+EFFECT Search WARBURG+EFFECT
3 CANCER METABOLISM 336841 4% 26% 76 Search CANCER+METABOLISM Search CANCER+METABOLISM
4 DICHLOROACETATE 263349 3% 25% 63 Search DICHLOROACETATE Search DICHLOROACETATE
5 GLUTAMINOLYSIS 239782 2% 34% 42 Search GLUTAMINOLYSIS Search GLUTAMINOLYSIS
6 GLYCOLYSIS 227421 12% 6% 214 Search GLYCOLYSIS Search GLYCOLYSIS
7 TIGAR 226647 1% 61% 22 Search TIGAR Search TIGAR
8 TUMOR METABOLISM 149027 2% 23% 39 Search TUMOR+METABOLISM Search TUMOR+METABOLISM
9 AEROBIC GLYCOLYSIS 138232 2% 19% 44 Search AEROBIC+GLYCOLYSIS Search AEROBIC+GLYCOLYSIS
10 LACTATE DEHYDROGENASE A 130790 1% 52% 15 Search LACTATE+DEHYDROGENASE+A Search LACTATE+DEHYDROGENASE+A

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ALTMAN, BJ , STINE, ZE , DANG, CV , (2016) FROM KREBS TO CLINIC: GLUTAMINE METABOLISM TO CANCER THERAPY.NATURE REVIEWS CANCER. VOL. 16. ISSUE 10. P. 619 -634 107 47% 5
2 PAVLOVA, NN , THOMPSON, CB , (2016) THE EMERGING HALLMARKS OF CANCER METABOLISM.CELL METABOLISM. VOL. 23. ISSUE 1. P. 27 -47 57 26% 76
3 AZEVEDO-SILVA, J , QUEIROS, O , BALTAZAR, F , UASZEWSKI, S , GOFFEAU, A , KO, YH , PEDERSEN, PL , PRETO, A , CASAL, M , (2016) THE ANTICANCER AGENT 3-BROMOPYRUVATE: A SIMPLE BUT POWERFUL MOLECULE TAKEN FROM THE LAB TO THE BEDSIDE.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. VOL. 48. ISSUE 4. P. 349 -362 72 68% 1
4 JIN, L , ALESI, GN , KANG, S , (2016) GLUTAMINOLYSIS AS A TARGET FOR CANCER THERAPY.ONCOGENE. VOL. 35. ISSUE 28. P. 3619 -3625 53 62% 9
5 DE VITTO, H , PEREZ-VALENCIA, J , RADOSEVICH, JA , (2016) GLUTAMINE AT FOCUS: VERSATILE ROLES IN CANCER.TUMOR BIOLOGY. VOL. 37. ISSUE 2. P. 1541 -1558 72 54% 3
6 BOROUGHS, LK , DEBERARDINIS, RJ , (2015) METABOLIC PATHWAYS PROMOTING CANCER CELL SURVIVAL AND GROWTH.NATURE CELL BIOLOGY. VOL. 17. ISSUE 4. P. 351 -359 47 47% 90
7 ZHAO, Y , BUTLER, EB , TAN, M , (2013) TARGETING CELLULAR METABOLISM TO IMPROVE CANCER THERAPEUTICS.CELL DEATH & DISEASE. VOL. 4. ISSUE . P. - 49 43% 266
8 MARTINEZ-OUTSCHOORN, UE , PEIRIS-PAGES, M , PESTELL, RG , SOTGIA, F , LISANTI, MP , (2017) CANCER METABOLISM: A THERAPEUTIC PERSPECTIVE.NATURE REVIEWS CLINICAL ONCOLOGY. VOL. 14. ISSUE 1. P. 11 -31 58 28% 3
9 RAUCKHORST, AJ , TAYLOR, EB , (2016) MITOCHONDRIAL PYRUVATE CARRIER FUNCTION AND CANCER METABOLISM.CURRENT OPINION IN GENETICS & DEVELOPMENT. VOL. 38. ISSUE . P. 102 -109 53 75% 0
10 KATT, WP , LUKEY, MJ , CERIONE, RA , (2017) A TALE OF TWO GLUTAMINASES: HOMOLOGOUS ENZYMES WITH DISTINCT ROLES IN TUMORIGENESIS.FUTURE MEDICINAL CHEMISTRY. VOL. 9. ISSUE 2. P. 223 -243 62 60% 0

Classes with closest relation at Level 1


Rank Class id link
1 25798 2 DEOXY D GLUCOSE//CELL BIOL R 124//METABOLIC OXIDATIVE STRESS
2 25763 FERMENTED WHEAT GERM EXTRACT//TKTL1//AVEMAR
3 8765 PKM2//PYRUVATE KINASE//PYRUVATE KINASE DEFICIENCY
4 15197 HEXOKINASE//HEXOKINASE II//BRAIN HEXOKINASE
5 16746 T CELL METABOLISM//IMMUNOMETABOLISM//VANDERBILT IMMUNOBIOL
6 9675 MONOCARBOXYLATE TRANSPORTER//LACTATE TRANSPORT//MCT1
7 29120 H ATP SYNTHASE//BETA F1 ATPASE MRNA//CSIC BIOL MOLEC BIOL MOLEC
8 11181 GLUT1//GLUCOSE TRANSPORTER//GLUT3
9 10148 FATTY ACID SYNTHASE//FASN//C75
10 29519 EXTRACELLULAR FLUX//COMPOUND SAFETY PREDICT//UAB MITOCHONDRIAL MED

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