Class information for:
Level 1: THERMOLYSIN//NEUTRAL PROTEASE//HALOPHILICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21813 404 34.9 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
427 3       JOURNAL OF THE INSTITUTE OF BREWING//KERATINASE//CYSTATIN 27946
1547 2             KERATINASE//ALKALINE PROTEASE//ASPARTIC PROTEINASE 7420
21813 1                   THERMOLYSIN//NEUTRAL PROTEASE//HALOPHILICITY 404

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THERMOLYSIN authKW 1191603 15% 26% 61
2 NEUTRAL PROTEASE authKW 383089 5% 24% 21
3 HALOPHILICITY authKW 302323 1% 67% 6
4 BOVINE INTESTINE ALKALINE PHOSPHATASE authKW 226745 1% 100% 3
5 FAB2 MU FRAGMENT authKW 226745 1% 100% 3
6 HYDROPHOBIC INTERACTION HPLC authKW 170057 1% 75% 3
7 MATRIX METALLOPROTEINASE MMP 7 authKW 170057 1% 75% 3
8 SALT ACTIVATION authKW 168332 2% 32% 7
9 FAB2 FRAGMENT authKW 160048 1% 35% 6
10 GLYCYL D PHENYLALANINE authKW 151163 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2800 67% 0% 272
2 Biotechnology & Applied Microbiology 637 18% 0% 72
3 Biophysics 545 14% 0% 57
4 Food Science & Technology 271 10% 0% 42
5 Biochemical Research Methods 268 9% 0% 38
6 Chemistry, Applied 112 6% 0% 23
7 Microbiology 107 8% 0% 33
8 Agronomy 10 2% 0% 8
9 Chemistry, Medicinal 9 2% 0% 9
10 Cell Biology 4 4% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRANCH BISCUITS 75582 0% 100% 1
2 BRANCHE BOISSONS 75582 0% 100% 1
3 DANISCO US INC 75582 0% 100% 1
4 EXPTL PATHOL CHIGUSA KU 75582 0% 100% 1
5 GENENCOR INT BV 75582 0% 100% 1
6 GRONINGEN BIOMOL SCI BIOTECCHNOL 75582 0% 100% 1
7 GRP RECH BIOMOL MICROENVRIONM METAB 75582 0% 100% 1
8 INSERM U 314 75582 0% 100% 1
9 ISSBM 75582 0% 100% 1
10 MED BIOL MOL STRUCT BIOL 75582 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOCHEMISTRY 12428 10% 0% 42
2 PROTEIN ENGINEERING 8541 4% 1% 16
3 JOURNAL OF FERMENTATION AND BIOENGINEERING 2760 2% 0% 9
4 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 2491 5% 0% 20
5 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 2431 2% 0% 9
6 MOLECULAR BIOLOGY 1291 2% 0% 9
7 JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS 973 1% 0% 5
8 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 867 1% 0% 5
9 SEIBUTSU-KOGAKU KAISHI-JOURNAL OF THE SOCIETY FOR FERMENTATION AND BIOENGINEERING 746 0% 1% 1
10 ADVANCES IN BIOPHYSICS 725 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 THERMOLYSIN 1191603 15% 26% 61 Search THERMOLYSIN Search THERMOLYSIN
2 NEUTRAL PROTEASE 383089 5% 24% 21 Search NEUTRAL+PROTEASE Search NEUTRAL+PROTEASE
3 HALOPHILICITY 302323 1% 67% 6 Search HALOPHILICITY Search HALOPHILICITY
4 BOVINE INTESTINE ALKALINE PHOSPHATASE 226745 1% 100% 3 Search BOVINE+INTESTINE+ALKALINE+PHOSPHATASE Search BOVINE+INTESTINE+ALKALINE+PHOSPHATASE
5 FAB2 MU FRAGMENT 226745 1% 100% 3 Search FAB2+MU+FRAGMENT Search FAB2+MU+FRAGMENT
6 HYDROPHOBIC INTERACTION HPLC 170057 1% 75% 3 Search HYDROPHOBIC+INTERACTION+HPLC Search HYDROPHOBIC+INTERACTION+HPLC
7 MATRIX METALLOPROTEINASE MMP 7 170057 1% 75% 3 Search MATRIX+METALLOPROTEINASE+MMP+7 Search MATRIX+METALLOPROTEINASE+MMP+7
8 SALT ACTIVATION 168332 2% 32% 7 Search SALT+ACTIVATION Search SALT+ACTIVATION
9 FAB2 FRAGMENT 160048 1% 35% 6 Search FAB2+FRAGMENT Search FAB2+FRAGMENT
10 GLYCYL D PHENYLALANINE 151163 0% 100% 2 Search GLYCYL+D+PHENYLALANINE Search GLYCYL+D+PHENYLALANINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KUSANO, M , YASUKAWA, K , INOUYE, K , (2009) INSIGHTS INTO THE CATALYTIC ROLES OF THE POLYPEPTIDE REGIONS IN THE ACTIVE SITE OF THERMOLYSIN AND GENERATION OF THE THERMOLYSIN VARIANTS WITH HIGH ACTIVITY AND STABILITY.JOURNAL OF BIOCHEMISTRY. VOL. 145. ISSUE 1. P. 103 -113 30 83% 6
2 KOJIMA, K , NAKATA, H , INOUYE, K , (2014) INVOLVEMENT OF VAL 315 LOCATED IN THE C-TERMINAL REGION OF THERMOLYSIN IN ITS EXPRESSION IN ESCHERICHIA COLI AND ITS THERMAL STABILITY.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1844. ISSUE 2. P. 330-338 25 83% 2
3 TATSUMI, C , HASHIDA, Y , YASUKAWA, K , INOUYE, K , (2007) EFFECTS OF SITE-DIRECTED MUTAGENESIS OF THE SURFACE RESIDUES GLN128 AND GLN225 OF THERMOLYSIN ON ITS CATALYTIC ACTIVITY.JOURNAL OF BIOCHEMISTRY. VOL. 141. ISSUE 6. P. 835-842 29 81% 5
4 YASUKAWA, K , INOUYE, K , (2007) IMPROVING THE ACTIVITY AND STABILITY OF THERMOLYSIN BY SITE-DIRECTED MUTAGENESIS.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1774. ISSUE 10. P. 1281-1288 27 82% 18
5 MENACH, E , YASUKAWA, K , INOUYE, K , (2010) EFFECTS OF SITE-DIRECTED MUTAGENESIS OF THE LOOP RESIDUE OF THE N-TERMINAL DOMAIN GLY117 OF THERMOLYSIN ON ITS CATALYTIC ACTIVITY.BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. VOL. 74. ISSUE 12. P. 2457 -2462 25 83% 4
6 HASHIDA, Y , INOUYE, K , (2007) MOLECULAR MECHANISM OF THE INHIBITORY EFFECT OF COBALT ION ON THERMOLYSIN ACTIVITY AND THE SUPPRESSIVE EFFECT OF CALCIUM ION ON THE COBALT ION-DEPENDENT INACTIVATION OF THERMOLYSIN.JOURNAL OF BIOCHEMISTRY. VOL. 141. ISSUE 6. P. 879-888 26 81% 5
7 TAKITA, T , AONO, T , SAKURAMA, H , ITOH, T , WADA, T , MINODA, M , YASUKAWA, K , INOUYE, K , (2008) EFFECTS OF INTRODUCING NEGATIVE CHARGES INTO THE MOLECULAR SURFACE OF THERMOLYSIN BY SITE-DIRECTED MUTAGENESIS ON ITS ACTIVITY AND STABILITY.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1784. ISSUE 3. P. 481 -488 24 77% 8
8 KAWASAKI, Y , YASUKAWA, K , INOUYE, K , (2013) EFFECTS OF SITE-DIRECTED MUTAGENESIS IN THE N-TERMINAL DOMAIN OF THERMOLYSIN ON ITS STABILIZATION.JOURNAL OF BIOCHEMISTRY. VOL. 153. ISSUE 1. P. 85-92 21 75% 4
9 MENACH, E , YASUKAWA, K , INOUYE, K , (2013) EFFECTS OF MUTATIONS OF THERMOLYSIN, ASN116 TO ASP AND ASP150 TO GLU, ON SALT-INDUCED ACTIVATION AND STABILIZATION.BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY. VOL. 77. ISSUE 4. P. 741 -746 18 75% 1
10 HASHIDA, Y , INOUYE, K , (2007) KINETIC ANALYSIS OF THE ACTIVATION-AND-INHIBITION DUAL EFFECTS OF COBALT ION ON THERMOLYSIN ACTIVITY.JOURNAL OF BIOCHEMISTRY. VOL. 141. ISSUE 6. P. 843-853 23 64% 9

Classes with closest relation at Level 1


Rank Class id link
1 11602 GLUTAMYL ENDOPEPTIDASE//SUBTILISIN//INTRAMOLECULAR CHAPERONE
2 21098 CARBOXYPEPTIDASE A//GENERAL ACID GENERAL BASE//5 BROMOACETYLSALICYLIC ACID
3 18228 VTB ENZYMTECHNOL//BACILLUS SUBTILIS//CSSRS
4 35410 SOYBEAN BETA AMYLASE//MALTAL//BETA AMYLASE
5 15175 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//T4 LYSOZYME
6 29809 M ECO RI//DNASE INHIBITOR//MICROBIAL ACE INHIBITORS
7 3611 KERATINASE//ALKALINE PROTEASE//FEATHER DEGRADATION
8 24459 CLOSTRIDIUM HISTOLYTICUM//BACILLUS LICHENIFORMIS F114//FISHERIES PROD TECHNOL
9 12643 PSYCHROPHILE//COLD ADAPTATION//THERMOPHILIC PROTEIN
10 3307 ENZYMATIC PEPTIDE SYNTHESIS//ALPHA CHYMOTRYPSIN//ORGANIC SOLVENTS

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