Class information for:
Level 1: BUTHIONINE SULFOXIMINE//L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE//5 OXO L PROLINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14435 769 32.9 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
285 3       ERDOSTEINE//PEROXIREDOXIN//GLUTATHIONE 42405
870 2             PEROXIREDOXIN//THIOREDOXIN//GLUTATHIONE 11539
14435 1                   BUTHIONINE SULFOXIMINE//L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE//5 OXO L PROLINASE 769

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BUTHIONINE SULFOXIMINE authKW 292672 6% 16% 46
2 L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE authKW 218375 1% 50% 11
3 5 OXO L PROLINASE authKW 178676 1% 75% 6
4 GLUTATHIONE MODULATION authKW 158826 1% 100% 4
5 5 OXOPROLINASE authKW 105881 1% 67% 4
6 SURG RADIOL PHYS MED address 102096 1% 43% 6
7 MERCURY ORANGE authKW 90754 1% 57% 4
8 BUTHIONINE SR SULFOXIMINE authKW 79413 0% 100% 2
9 VITABRIGHT 48 authKW 79413 0% 100% 2
10 WIDR COLON CANCER CELLS authKW 79413 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Radiology, Nuclear Medicine & Medical Imaging 3460 27% 0% 204
2 Oncology 3347 35% 0% 268
3 Biology 2613 17% 0% 130
4 Nuclear Science & Technology 974 11% 0% 85
5 Biophysics 363 9% 0% 68
6 Toxicology 287 7% 0% 50
7 Pharmacology & Pharmacy 263 13% 0% 101
8 Biochemistry & Molecular Biology 149 16% 0% 122
9 Cell Biology 122 8% 0% 65
10 Biochemical Research Methods 59 4% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SURG RADIOL PHYS MED 102096 1% 43% 6
2 KIMMELL CANC 52941 0% 67% 2
3 AUGUST PI SUNER IDIB S 39706 0% 100% 1
4 CANC TREATMENT EXPTL THER EUT METAB 39706 0% 100% 1
5 FLETCHER ALLEN HLTH CARE GEN CLIN 39706 0% 100% 1
6 G GASILINI 39706 0% 100% 1
7 HIGH TATVAN 39706 0% 100% 1
8 INVEST PORFIRINAS PORFIRISCIPYP 39706 0% 100% 1
9 LOMBARDI CANC RADIAT MED 39706 0% 100% 1
10 MED PEDIAT POB 2916 39706 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 44220 10% 1% 75
2 RADIATION RESEARCH 9635 5% 1% 40
3 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 8516 8% 0% 61
4 TOXIC SUBSTANCE MECHANISMS 2142 0% 3% 2
5 BIOCHEMICAL PHARMACOLOGY 2024 4% 0% 31
6 CANCER RESEARCH 1917 6% 0% 44
7 PHARMACOLOGY & THERAPEUTICS 1880 2% 0% 12
8 CYTOMETRY 1172 1% 0% 9
9 MELANOMA RESEARCH 1095 1% 0% 7
10 CELLULAR & MOLECULAR BIOLOGY RESEARCH 794 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BUTHIONINE SULFOXIMINE 292672 6% 16% 46 Search BUTHIONINE+SULFOXIMINE Search BUTHIONINE+SULFOXIMINE
2 L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE 218375 1% 50% 11 Search L+2+OXOTHIAZOLIDINE+4+CARBOXYLATE Search L+2+OXOTHIAZOLIDINE+4+CARBOXYLATE
3 5 OXO L PROLINASE 178676 1% 75% 6 Search 5+OXO+L+PROLINASE Search 5+OXO+L+PROLINASE
4 GLUTATHIONE MODULATION 158826 1% 100% 4 Search GLUTATHIONE+MODULATION Search GLUTATHIONE+MODULATION
5 5 OXOPROLINASE 105881 1% 67% 4 Search 5+OXOPROLINASE Search 5+OXOPROLINASE
6 MERCURY ORANGE 90754 1% 57% 4 Search MERCURY+ORANGE Search MERCURY+ORANGE
7 BUTHIONINE SR SULFOXIMINE 79413 0% 100% 2 Search BUTHIONINE+SR+SULFOXIMINE Search BUTHIONINE+SR+SULFOXIMINE
8 VITABRIGHT 48 79413 0% 100% 2 Search VITABRIGHT+48 Search VITABRIGHT+48
9 WIDR COLON CANCER CELLS 79413 0% 100% 2 Search WIDR+COLON+CANCER+CELLS Search WIDR+COLON+CANCER+CELLS
10 GLUTATHIONE 78645 20% 1% 156 Search GLUTATHIONE Search GLUTATHIONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MEISTER, A , (1991) GLUTATHIONE DEFICIENCY PRODUCED BY INHIBITION OF ITS SYNTHESIS, AND ITS REVERSAL - APPLICATIONS IN RESEARCH AND THERAPY.PHARMACOLOGY & THERAPEUTICS. VOL. 51. ISSUE 2. P. 155-194 54 32% 736
2 VILLABLANCA, JG , VOLCHENBOUM, SL , CHO, H , KANG, MH , COHN, SL , ANDERSON, CP , MARACHELIAN, A , GROSHEN, S , TSAO-WEI, D , MATTHAY, KK , ET AL (2016) A PHASE I NEW APPROACHES TO NEUROBLASTOMA THERAPY STUDY OF BUTHIONINE SULFOXIMINE AND MELPHALAN WITH AUTOLOGOUS STEM CELLS FOR RECURRENT/REFRACTORY HIGH-RISK NEUROBLASTOMA.PEDIATRIC BLOOD & CANCER. VOL. 63. ISSUE 8. P. 1349 -1356 23 53% 0
3 HEDLEY, DW , NICKLEE, T , MORENO-MERLO, F , PINTILIE, M , FYLES, A , MILOSEVIC, M , HILL, RP , (2005) RELATIONS BETWEEN NON-PROTEIN SULFYDRYL LEVELS IN THE NUCLEUS AND CYTOPLASM, TUMOR OXYGENATION, AND CLINICAL OUTCOME OF PATIENTS WITH UTERINE CERVICAL CARCINOMA.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 61. ISSUE 1. P. 137-144 18 86% 5
4 BAILEY, HH , (1998) L-S,R-BUTHIONINE SULFOXIMINE: HISTORICAL DEVELOPMENT AND CLINICAL ISSUES.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 112. ISSUE . P. 239-254 22 63% 37
5 DEL OLMO, M , ALONSO-VARONA, A , CASTRO, B , CALLE, Y , BILBAO, P , PALOMARES, T , (2000) EFFECTS OF L-2-OXOTHIAZOLIDINE-4-CARBOXYLATE ON THE CYTOTOXIC ACTIVITY AND TOXICITY OF CYCLOPHOSPHAMIDE IN MICE BEARING B16F10 MELANOMA LIVER METASTASES.MELANOMA RESEARCH. VOL. 10. ISSUE 2. P. 103-112 20 67% 10
6 VUKOVIC, V , NICKLEE, T , HEDLEY, DW , (2000) MICROREGIONAL HETEROGENEITY OF NON-PROTEIN THIOLS IN CERVICAL CARCINOMAS ASSESSED BY COMBINED USE OF HPLC AND FLUORESCENCE IMAGE ANALYSIS.CLINICAL CANCER RESEARCH. VOL. 6. ISSUE 5. P. 1826-1832 20 65% 13
7 SIEMANN, DW , BEYERS, KL , (1993) IN-VIVO THERAPEUTIC POTENTIAL OF COMBINATION THIOL DEPLETION AND ALKYLATING CHEMOTHERAPY.BRITISH JOURNAL OF CANCER. VOL. 68. ISSUE 6. P. 1071-1079 20 80% 41
8 CHATTOPADHYAY, A , DEB, S , CHATTERJEE, A , (1999) MODULATION OF THE CLASTOGENIC ACTIVITY OF GAMMA-IRRADIATION IN BUTHIONINE SULPHOXIMINE-MEDIATED GLUTATHIONE DEPLETED MAMMALIAN CELLS.INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. VOL. 75. ISSUE 10. P. 1283 -1291 23 58% 15
9 HALPERIN, EC , BRIZEL, DM , HONORE, G , SONTAG, MR , GRIFFITH, OW , BIGNER, DD , FRIEDMAN, HS , (1992) THE RADIATION DOSE-RESPONSE RELATIONSHIP IN A HUMAN GLIOMA XENOGRAFT AND AN EVALUATION OF THE INFLUENCE OF GLUTATHIONE DEPLETION BY BUTHIONINE SULFOXIMINE.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 24. ISSUE 1. P. 103-109 26 67% 7
10 BUMP, EA , BROWN, JM , (1990) ROLE OF GLUTATHIONE IN THE RADIATION RESPONSE OF MAMMALIAN-CELLS INVITRO AND INVIVO.PHARMACOLOGY & THERAPEUTICS. VOL. 47. ISSUE 1. P. 117-136 38 38% 195

Classes with closest relation at Level 1


Rank Class id link
1 9841 ETANIDAZOLE//HYPOXIC CELL SENSITIZER//HYPOXIC CELL RADIOSENSITIZER
2 14974 MITOCHONDRIAL APOPTOSIS SIGNALING//APOPTOSIS IN UNDIFFERENTIATED CELLS//GSH COMPARTMENTATION
3 16464 GLUTAMATE CYSTEINE LIGASE//GAMMA GLUTAMYLCYSTEINE SYNTHETASE//GLUTATHIONE SYNTHETASE
4 14457 CISPLATIN RESISTANCE//RAT OVARIAN TUMOR CELL LINES//TCRP1
5 24411 ADP DEPENDENT GLUCOKINASE ADPGK//ANTI METHYLDITHIO FACTOR//ASSAY FOR METHYLTHIO DISULFIDES
6 33762 2 C 14GRAMINE//2 C 14INDOLE 3 CARBOXYLIC ACID//2 H 3INDOLE 3 CARBOXALDEHYDE
7 9883 AMIFOSTINE//WR 2721//WR 1065
8 20094 MELPHALAN//CHLORAMBUCIL//PREDNIMUSTINE
9 25710 CYSTEAMINYLPHENOL//5 S GAD//ANTIMELANOMA
10 7496 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH//L5178Y MURINE LYMPHOMA SUBLINES

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