Class information for:
Level 1: CYSTEAMINYLPHENOL//5 S GAD//ANTIMELANOMA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25710 274 27.1 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
633 3       TYROSINASE//MELANOGENESIS//PIGMENT CELL RESEARCH 12915
1583 2             TYROSINASE//MELANOGENESIS//PIGMENT CELL RESEARCH 7222
25710 1                   CYSTEAMINYLPHENOL//5 S GAD//ANTIMELANOMA 274

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYSTEAMINYLPHENOL authKW 682584 3% 88% 7
2 5 S GAD authKW 546065 3% 70% 7
3 ANTIMELANOMA authKW 364716 2% 55% 6
4 HYDROXYANISOLE authKW 356615 1% 80% 4
5 4 S CYSTEAMINYLPHENOL authKW 334328 1% 100% 3
6 N PROPIONYL 4 S CYSTEAMINYLPHENOL authKW 334328 1% 100% 3
7 SK MEL 5 authKW 334328 1% 100% 3
8 SK MEL 28 authKW 273025 3% 35% 7
9 B16 F0 authKW 250744 1% 75% 3
10 MELANOCYTE TOXICITY authKW 250744 1% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Dermatology 2228 22% 0% 60
2 Oncology 748 28% 0% 77
3 Chemistry, Medicinal 334 11% 0% 30
4 Pharmacology & Pharmacy 277 20% 0% 56
5 Toxicology 68 5% 0% 15
6 Cell Biology 43 8% 0% 23
7 Biochemistry & Molecular Biology 41 15% 0% 40
8 Medicine, Research & Experimental 37 5% 0% 15
9 Chemistry, Organic 32 7% 0% 18
10 Chemistry, Multidisciplinary 13 8% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NATORI 200594 1% 60% 3
2 BIOMED POLYMERSSTATE VIROL 111443 0% 100% 1
3 CRITICAL TECHNOL PL SCI 111443 0% 100% 1
4 DENT PHAM 3118 111443 0% 100% 1
5 TARIX PHARMA CONSULTANCY SCI TECHNOL 111443 0% 100% 1
6 TRIAL FORM SUPPORT 111443 0% 100% 1
7 UNIV MIDDLESEX MED CHEM PATHOL 111443 0% 100% 1
8 PATERSON CANC CRC BIOPHYS CHEM 89152 1% 40% 2
9 DIPARTIMENTO SCI ONCOL CHIRUG 55720 0% 50% 1
10 HERITAGE MED 260G 55720 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PIGMENT CELL RESEARCH 20329 5% 1% 14
2 MELANOMA RESEARCH 9125 4% 1% 12
3 BIOGENIC AMINES 7014 3% 1% 7
4 JOURNAL OF INVESTIGATIVE DERMATOLOGY 4654 8% 0% 21
5 BIOCHEMICAL PHARMACOLOGY 2905 8% 0% 22
6 CLINICAL ONCOLOGY MONOGRAPHS 2272 0% 2% 1
7 PIGMENT CELL & MELANOMA RESEARCH 1738 1% 1% 3
8 ANTI-CANCER DRUG DESIGN 1594 1% 0% 3
9 MEDICAL SCIENCE RESEARCH-BIOCHEMISTRY 1182 1% 1% 2
10 CHEMICO-BIOLOGICAL INTERACTIONS 956 3% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYSTEAMINYLPHENOL 682584 3% 88% 7 Search CYSTEAMINYLPHENOL Search CYSTEAMINYLPHENOL
2 5 S GAD 546065 3% 70% 7 Search 5+S+GAD Search 5+S+GAD
3 ANTIMELANOMA 364716 2% 55% 6 Search ANTIMELANOMA Search ANTIMELANOMA
4 HYDROXYANISOLE 356615 1% 80% 4 Search HYDROXYANISOLE Search HYDROXYANISOLE
5 4 S CYSTEAMINYLPHENOL 334328 1% 100% 3 Search 4+S+CYSTEAMINYLPHENOL Search 4+S+CYSTEAMINYLPHENOL
6 N PROPIONYL 4 S CYSTEAMINYLPHENOL 334328 1% 100% 3 Search N+PROPIONYL+4+S+CYSTEAMINYLPHENOL Search N+PROPIONYL+4+S+CYSTEAMINYLPHENOL
7 SK MEL 5 334328 1% 100% 3 Search SK+MEL+5 Search SK+MEL+5
8 SK MEL 28 273025 3% 35% 7 Search SK+MEL+28 Search SK+MEL+28
9 B16 F0 250744 1% 75% 3 Search B16+F0 Search B16+F0
10 MELANOCYTE TOXICITY 250744 1% 75% 3 Search MELANOCYTE+TOXICITY Search MELANOCYTE+TOXICITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RILEY, PA , (2003) MELANOGENESIS AND MELANOMA.PIGMENT CELL RESEARCH. VOL. 16. ISSUE 5. P. 548 -552 21 58% 65
2 ISHII-OSAI, Y , YAMASHITA, T , TAMURA, Y , SATO, N , ITO, A , HONDA, H , WAKAMATSU, K , ITO, S , NAKAYAMA, E , OKURA, M , ET AL (2012) N-PROPIONYL-4-S-CYSTEAMINYLPHENOL INDUCES APOPTOSIS IN B16F1 CELLS AND MEDIATES TUMOR-SPECIFIC T-CELL IMMUNE RESPONSES IN A MOUSE MELANOMA MODEL.JOURNAL OF DERMATOLOGICAL SCIENCE. VOL. 67. ISSUE 1. P. 51 -60 19 53% 2
3 VAD, NM , KANDALA, PK , SRIVASTAVA, SK , MORIDANI, MY , (2010) STRUCTURE-TOXICITY RELATIONSHIP OF PHENOLIC ANALOGS AS ANTI-MELANOMA AGENTS: AN ENZYME DIRECTED PRODRUG APPROACH.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 183. ISSUE 3. P. 462-471 15 68% 4
4 JAWAID, S , KHAN, TH , OSBORN, HMI , WILLIAMS, NAO , (2009) TYROSINASE ACTIVATED MELANOMA PRODRUGS.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 9. ISSUE 7. P. 717-727 27 37% 13
5 KOBAYASHI, M , NISHII, R , SHIKANO, N , FLORES, LG , MIZUTANI, A , OGAI, K , SUGAMA, J , NAGAMACHI, S , KAWAI, K , (2015) DEVELOPMENT OF RADIOIODINE-LABELED 4-HYDROXYPHENYLCYSTEAMINE FOR SPECIFIC DIAGNOSIS OF MALIGNANT MELANOMA.NUCLEAR MEDICINE AND BIOLOGY. VOL. 42. ISSUE 6. P. 536 -540 12 71% 0
6 HASEGAWA, K , ITO, S , INOUE, S , WAKAMATSU, K , OZEKI, H , ISHIGURO, I , (1997) DIHYDRO-1,4-BENZOTHIAZINE-6,7-DIONE, THE ULTIMATE TOXIC METABOLITE OF 4-S-CYSTEAMINYLPHENOL AND 4-S-CYSTEAMINYLCATECHOL.BIOCHEMICAL PHARMACOLOGY. VOL. 53. ISSUE 10. P. 1435-1444 17 77% 22
7 YUKITAKE, J , OTAKE, H , INOUE, S , WAKAMATSU, K , ITO, S , (2004) COMPARISON OF IN VIVO ANTI-MELANOMA EFFECT OF ENANTIOMERIC ALPHA-METHYL- AND ALPHA-ETHYL-4-S-CYSTEAMINYLPHENOL.MELANOMA RESEARCH. VOL. 14. ISSUE 2. P. 115-120 15 71% 2
8 JIMBOW, K , IWASHINA, T , ALENA, F , YAMADA, K , PANKOVICH, J , UMEMURA, T , (1993) EXPLOITATION OF PIGMENT BIOSYNTHESIS PATHWAY AS A SELECTIVE CHEMOTHERAPEUTIC APPROACH FOR MALIGNANT-MELANOMA.JOURNAL OF INVESTIGATIVE DERMATOLOGY. VOL. 100. ISSUE 2. P. S231-S238 20 74% 26
9 KNAGGS, S , MALKIN, H , OSBORN, HMI , WILLIAMS, NAO , YAQOOB, P , (2005) NEW PRODRUGS DERIVED FROM 6-AMINODOPAMINE AND 4-AMINOPHENOL AS CANDIDATES FOR MELANOCYTE-DIRECTED ENZYME PRODRUG THERAPY (MDEPT).ORGANIC & BIOMOLECULAR CHEMISTRY. VOL. 3. ISSUE 21. P. 4002 -4010 17 52% 23
10 VAD, NM , KUDUGUNTI, SK , GRABER, D , BAILEY, N , SRIVENUGOPAL, K , MORIDANI, MY , (2009) EFFICACY OF ACETAMINOPHEN IN SKIN B16-F0 MELANOMA TUMOR-BEARING C57BL/6 MICE.INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 35. ISSUE 1. P. 193-204 13 57% 3

Classes with closest relation at Level 1


Rank Class id link
1 31685 AGING NEUROEPIDEMIOL GRP//1 3 BIS 2 CHLOROETHYL 1 NITROSOUREA//AMYOTROPHIC LATERAL SCLEROSIS MORTALITY
2 7357 TYROSINASE INHIBITOR//MUSHROOM TYROSINASE//TYROSINASE
3 5716 EUMELANIN//MELANIN//PHEOMELANIN
4 30827 DODECANEDIOIC ACID//DIETHYL SEBACATE//AZELAIC ACID
5 20544 MELANOMA IMAGING//IMAGERIE MOL THER IE VECTORISEE//ALPHA MELANOCYTE STIMULATING HORMONE HYBRID PEPTIDE
6 705 MELANOGENESIS//TYROSINASE//MELANOCYTE
7 36618 FININGS//EA 1116//INCOMPLETE APOPTOSIS
8 14435 BUTHIONINE SULFOXIMINE//L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE//5 OXO L PROLINASE
9 22761 METHIONINE DEPENDENCE//METHIONINASE//METHIONINE GAMMA LYASE
10 34365 ADRENERGIC NERVOUS SYSTEM NGF INTERACTION//ASYMPTOMATIC MULTIPLE MYELOMA//BEILINSON MED SACKLER MED ONCOL

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