Class information for:
Level 1: ETANIDAZOLE//HYPOXIC CELL SENSITIZER//HYPOXIC CELL RADIOSENSITIZER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9841 1115 25.7 48%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
1363 2             TIRAPAZAMINE//DT DIAPHORASE//BIOREDUCTIVE DRUGS 8244
9841 1                   ETANIDAZOLE//HYPOXIC CELL SENSITIZER//HYPOXIC CELL RADIOSENSITIZER 1115

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ETANIDAZOLE authKW 514137 3% 57% 33
2 HYPOXIC CELL SENSITIZER authKW 490882 2% 81% 22
3 HYPOXIC CELL RADIOSENSITIZER authKW 476245 2% 87% 20
4 KU 2285 authKW 385091 1% 94% 15
5 SR 2508 authKW 385091 1% 94% 15
6 DORANIDAZOLE authKW 228200 1% 83% 10
7 SANAZOLE authKW 195597 1% 71% 10
8 AK 2123 authKW 167728 1% 88% 7
9 HYPOXIC RADIOSENSITIZER authKW 149090 1% 78% 7
10 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS journal 140619 27% 2% 297

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Radiology, Nuclear Medicine & Medical Imaging 15876 46% 0% 514
2 Oncology 14825 59% 0% 659
3 Biology 1842 12% 0% 134
4 Pharmacology & Pharmacy 371 13% 0% 145
5 Nuclear Science & Technology 314 6% 0% 63
6 Biophysics 292 7% 0% 77
7 Chemistry, Medicinal 129 4% 0% 44
8 Toxicology 16 2% 0% 22
9 CYTOLOGY & HISTOLOGY 2 0% 0% 1
10 Chemistry, Analytical 0 2% 0% 20

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANSIM INTERNAL MED CLIN 27384 0% 100% 1
2 CANC TREATMENTRADIAT ONCOL BRANCH 27384 0% 100% 1
3 CLIN ONCOL PROGRAMBLDG 10 B3B69 27384 0% 100% 1
4 DEV PART HAKATA KU 27384 0% 100% 1
5 MED DENTENVIRONM HLTH SCI 27384 0% 100% 1
6 MED GYNECOL OBSTET GYNECOL ONCOL SECT 27384 0% 100% 1
7 MED PATHOL ONCOL SECT 27384 0% 100% 1
8 PHARMACEUT DEV S TOTSUKA KU 27384 0% 100% 1
9 PHARMACEUT RD S TOTSUKU KU 27384 0% 100% 1
10 PL IMU LASEISIC 27384 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 140619 27% 2% 297
2 CANCER CLINICAL TRIALS 94313 2% 16% 21
3 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 17562 5% 1% 57
4 BRITISH JOURNAL OF CANCER 15253 9% 1% 100
5 RADIATION RESEARCH 14955 5% 1% 60
6 STRAHLENTHERAPIE 5897 1% 2% 12
7 BIOCHEMICAL PHARMACOLOGY 3214 4% 0% 47
8 CANCER TREATMENT REPORTS 2771 1% 1% 15
9 RADIOTHERAPY AND ONCOLOGY 2401 2% 0% 23
10 ANTI-CANCER DRUG DESIGN 2126 1% 1% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ETANIDAZOLE 514137 3% 57% 33 Search ETANIDAZOLE Search ETANIDAZOLE
2 HYPOXIC CELL SENSITIZER 490882 2% 81% 22 Search HYPOXIC+CELL+SENSITIZER Search HYPOXIC+CELL+SENSITIZER
3 HYPOXIC CELL RADIOSENSITIZER 476245 2% 87% 20 Search HYPOXIC+CELL+RADIOSENSITIZER Search HYPOXIC+CELL+RADIOSENSITIZER
4 KU 2285 385091 1% 94% 15 Search KU+2285 Search KU+2285
5 SR 2508 385091 1% 94% 15 Search SR+2508 Search SR+2508
6 DORANIDAZOLE 228200 1% 83% 10 Search DORANIDAZOLE Search DORANIDAZOLE
7 SANAZOLE 195597 1% 71% 10 Search SANAZOLE Search SANAZOLE
8 AK 2123 167728 1% 88% 7 Search AK+2123 Search AK+2123
9 HYPOXIC RADIOSENSITIZER 149090 1% 78% 7 Search HYPOXIC+RADIOSENSITIZER Search HYPOXIC+RADIOSENSITIZER
10 KIN 804 136922 0% 100% 5 Search KIN+804 Search KIN+804

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WAGENER, J , BEYRICH, T , (1992) RADIOSENSITIZERS - BIOCHEMISTRY AND EXPERIENCES OF TUMOR-THERAPY.PHARMAZIE. VOL. 47. ISSUE 11. P. 815-824 50 69% 0
2 SIEMANN, DW , (1984) MODIFICATION OF CHEMOTHERAPY BY NITROIMIDAZOLES.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 10. ISSUE 9. P. 1585-1594 48 96% 71
3 ELGAMOUSSI, R , STRATFORD, IJ , GUICHARD, M , (1993) RELATIONSHIP BETWEEN INTRACELLULAR CONCENTRATION AND RADIOSENSITIZING EFFECT OF PIMONIDAZOLE AND ETANIDAZOLE ON 2 HUMAN-MELANOMA CELL-LINES.INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. VOL. 63. ISSUE 1. P. 27-36 32 89% 2
4 SUGIE, C , SHIBAMOTO, Y , ITO, M , OGINO, H , SUZUKI, H , UTO, Y , NAGASAWA, H , HORI, H , (2005) REEVALUATION OF THE RADIOSENSITIZING EFFECTS OF SANAZOLE AND NIMORAZOLE IN VITRO AND IN VIVO.JOURNAL OF RADIATION RESEARCH. VOL. 46. ISSUE 4. P. 453-459 22 73% 21
5 SIEMANN, DW , MULCAHY, RT , (1986) SENSITIZATION OF CANCER CHEMOTHERAPEUTIC-AGENTS BY NITROHETEROCYCLICS.BIOCHEMICAL PHARMACOLOGY. VOL. 35. ISSUE 1. P. 111-115 35 100% 22
6 COLEMAN, CN , BUMP, EA , KRAMER, RA , (1988) CHEMICAL MODIFIERS OF CANCER-TREATMENT.JOURNAL OF CLINICAL ONCOLOGY. VOL. 6. ISSUE 4. P. 709-733 77 35% 77
7 ELGAMOUSSI, R , THREADGILL, MD , PRADE, M , STRATFORD, IJ , GUICHARD, M , (1993) RELATIONSHIP BETWEEN THE MELANIN CONTENT OF A HUMAN-MELANOMA CELL-LINE AND ITS RADIOSENSITIVITY AND UPTAKE OF PIMONIDAZOLE.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 31. ISSUE 4. P. 277-282 30 79% 2
8 SAPORA, O , PAONE, A , MAGGI, A , JENNER, TJ , ONEILL, P , (1992) INDUCTION OF MUTATIONS IN V79-4 MAMMALIAN-CELLS UNDER HYPOXIC AND AEROBIC CONDITIONS BY THE CYTOTOXIC 2-NITROIMIDAZOLE-AZIRIDINES, RSU-1069 AND RSU-1131 - THE INFLUENCE OF CELLULAR GLUTATHIONE.BIOCHEMICAL PHARMACOLOGY. VOL. 44. ISSUE 7. P. 1341-1347 26 93% 5
9 TAGHIAN, A , LESPINASSE, F , GUICHARD, ME , (1991) RADIOSENSITIZATION BY THE COMBINATION OF ETANIDAZOLE (SR-2508) AND PIMONIDAZOLE (RO 03-8799) IN HUMAN TUMOR XENOGRAFTS.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 21. ISSUE 6. P. 1535-1540 26 93% 8
10 JIN, C , BAI, L , GUO, GZ , (2007) RADIOSENSITIZATION BY THE COMBINATION OF SR-2508 AND PACLITAXEL IN HYPOXIC HUMAN TUMOR CELLS IN VITRO.JOURNAL OF RADIATION RESEARCH. VOL. 48. ISSUE 3. P. 179-185 18 75% 1

Classes with closest relation at Level 1


Rank Class id link
1 15678 TIRAPAZAMINE//BIOREDUCTIVE DRUGS//SR 4233
2 14435 BUTHIONINE SULFOXIMINE//L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE//5 OXO L PROLINASE
3 2109 CARBOGEN//TUMOR HYPOXIA//TUMOR OXYGENATION
4 9104 METRONIDAZOLE//NITRO RADICAL ANION//DIMETRIDAZOLE
5 27229 MED MEANS CHEM//1 ARYL 4 NITROIMIDAZOLES//1 4 DINITROIMIDAZOLES
6 22025 DRUG EFFECT ON BRAIN//PT 191 CISPLATIN//LIPOPLATIN TM
7 33762 2 C 14GRAMINE//2 C 14INDOLE 3 CARBOXYLIC ACID//2 H 3INDOLE 3 CARBOXALDEHYDE
8 35768 QUIESCENT CELL//BORON TRACEDRUG//MILD TEMPERATURE HYPERTHERMIA
9 14991 MULTICELLULAR SPHEROIDS//MULTICELLULAR TUMOR SPHEROIDS//SPHEROID
10 9883 AMIFOSTINE//WR 2721//WR 1065

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