Class information for:
Level 1: ALDEHYDE OXIDASE//XANTHINE DEHYDROGENASE//XANTHINE OXIDOREDUCTASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13862 808 36.1 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
613 3       GOUT//HYPERURICEMIA//URIC ACID 14056
1622 2             GOUT//HYPERURICEMIA//URIC ACID 7034
13862 1                   ALDEHYDE OXIDASE//XANTHINE DEHYDROGENASE//XANTHINE OXIDOREDUCTASE 808

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALDEHYDE OXIDASE authKW 1658331 12% 46% 96
2 XANTHINE DEHYDROGENASE authKW 490978 6% 28% 47
3 XANTHINE OXIDOREDUCTASE authKW 490099 5% 31% 42
4 XANTHINE OXIDASE authKW 368337 15% 8% 119
5 RS 8359 authKW 255077 1% 75% 9
6 XANTHINURIA authKW 236179 1% 63% 10
7 HEREDITARY XANTHINURIA authKW 151159 0% 100% 4
8 AOX1 authKW 123670 1% 55% 6
9 MOLYBDO FLAVOENZYME authKW 118090 1% 63% 5
10 ALDEHYDE OXIDASE 1 authKW 113370 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1546 27% 0% 218
2 Biochemistry & Molecular Biology 1192 34% 0% 275
3 Biophysics 509 10% 0% 81
4 Toxicology 221 6% 0% 46
5 Cell Biology 117 8% 0% 66
6 Medical Laboratory Technology 101 2% 0% 17
7 Chemistry, Medicinal 80 4% 0% 30
8 Medicine, Research & Experimental 72 5% 0% 38
9 Endocrinology & Metabolism 59 5% 0% 37
10 Physiology 49 4% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG DISCOVERY SUPPORT DMPK 85026 0% 75% 3
2 PHARMACOL STUDY GRP 85026 0% 75% 3
3 I DEV GRP 75580 0% 100% 2
4 RADIOISOTOPE CHEM ANAL 68019 0% 60% 3
5 WEBB WARING ANTIOXIDANT 60459 0% 40% 4
6 ABTEILUNGSLEITER TEILBEREICH MOL GENET 37790 0% 100% 1
7 ANALYT RUMENTAT UNIT 37790 0% 100% 1
8 BTIS SUB 37790 0% 100% 1
9 CARDIOL HYPERTENS INTERVENT ELE OCARDIOL 37790 0% 100% 1
10 CARDIOVASC DISKU LEUVEN 37790 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG METABOLISM AND DISPOSITION 14645 7% 1% 54
2 XENOBIOTICA 6567 3% 1% 26
3 DRUG METABOLISM AND PHARMACOKINETICS 4228 1% 1% 9
4 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 2379 4% 0% 33
5 BIOCHEMICAL PHARMACOLOGY 1345 3% 0% 26
6 FREE RADICAL BIOLOGY AND MEDICINE 1101 2% 0% 16
7 REDOX REPORT 999 1% 1% 5
8 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 911 1% 0% 8
9 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 874 1% 0% 6
10 JOURNAL OF THE AMERICAN AGING ASSOCIATION 785 0% 2% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ALDEHYDE OXIDASE 1658331 12% 46% 96 Search ALDEHYDE+OXIDASE Search ALDEHYDE+OXIDASE
2 XANTHINE DEHYDROGENASE 490978 6% 28% 47 Search XANTHINE+DEHYDROGENASE Search XANTHINE+DEHYDROGENASE
3 XANTHINE OXIDOREDUCTASE 490099 5% 31% 42 Search XANTHINE+OXIDOREDUCTASE Search XANTHINE+OXIDOREDUCTASE
4 XANTHINE OXIDASE 368337 15% 8% 119 Search XANTHINE+OXIDASE Search XANTHINE+OXIDASE
5 RS 8359 255077 1% 75% 9 Search RS+8359 Search RS+8359
6 XANTHINURIA 236179 1% 63% 10 Search XANTHINURIA Search XANTHINURIA
7 HEREDITARY XANTHINURIA 151159 0% 100% 4 Search HEREDITARY+XANTHINURIA Search HEREDITARY+XANTHINURIA
8 AOX1 123670 1% 55% 6 Search AOX1 Search AOX1
9 MOLYBDO FLAVOENZYME 118090 1% 63% 5 Search MOLYBDO+FLAVOENZYME Search MOLYBDO+FLAVOENZYME
10 ALDEHYDE OXIDASE 1 113370 0% 100% 3 Search ALDEHYDE+OXIDASE+1 Search ALDEHYDE+OXIDASE+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GARATTINI, E , TERAO, M , (2012) THE ROLE OF ALDEHYDE OXIDASE IN DRUG METABOLISM.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 8. ISSUE 4. P. 487 -503 70 77% 49
2 KITAMURA, S , SUGIHARA, K , OHTA, S , (2006) DRUG-METABOLIZING ABILITY OF MOLYBDENUM HYDROXYLASES.DRUG METABOLISM AND PHARMACOKINETICS. VOL. 21. ISSUE 2. P. 83-98 88 68% 97
3 SANOH, S , TAYAMA, Y , SUGIHARA, K , KITAMURA, S , OHTA, S , (2015) SIGNIFICANCE OF ALDEHYDE OXIDASE DURING DRUG DEVELOPMENT: EFFECTS ON DRUG METABOLISM, PHARMACOKINETICS, TOXICITY, AND EFFICACY.DRUG METABOLISM AND PHARMACOKINETICS. VOL. 30. ISSUE 1. P. 52 -63 72 69% 7
4 TERAO, M , ROMAO, MJ , LEIMKUHLER, S , BOLIS, M , FRATELLI, M , COELHO, C , SANTOS-SILVA, T , GARATTINI, E , (2016) STRUCTURE AND FUNCTION OF MAMMALIAN ALDEHYDE OXIDASES.ARCHIVES OF TOXICOLOGY. VOL. 90. ISSUE 4. P. 753 -780 75 54% 2
5 DALVIE, D , XIANG, C , KANG, P , ZHOU, S , (2013) INTERSPECIES VARIATION IN THE METABOLISM OF ZONIPORIDE BY ALDEHYDE OXIDASE.XENOBIOTICA. VOL. 43. ISSUE 5. P. 399-408 51 91% 11
6 GARATTINI, E , TERAO, M , (2013) ALDEHYDE OXIDASE AND ITS IMPORTANCE IN NOVEL DRUG DISCOVERY: PRESENT AND FUTURE CHALLENGES.EXPERT OPINION ON DRUG DISCOVERY. VOL. 8. ISSUE 6. P. 641-654 51 77% 15
7 PRYDE, DC , DALVIE, D , HU, QY , JONES, P , OBACH, RS , TRAN, TD , (2010) ALDEHYDE OXIDASE: AN ENZYME OF EMERGING IMPORTANCE IN DRUG DISCOVERY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 53. ISSUE 24. P. 8441 -8460 58 60% 105
8 BATTELLI, MG , BOLOGNESI, A , POLITO, L , (2014) PATHOPHYSIOLOGY OF CIRCULATING XANTHINE OXIDOREDUCTASE: NEW EMERGING ROLES FOR A MULTI-TASKING ENZYME.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1842. ISSUE 9. P. 1502 -1517 88 36% 26
9 GARATTINI, E , FRATELLI, M , TERAO, M , (2008) MAMMALIAN ALDEHYDE OXIDASES: GENETICS, EVOLUTION AND BIOCHEMISTRY.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 65. ISSUE 7-8. P. 1019-1048 69 46% 82
10 HARRISON, R , (2002) STRUCTURE AND FUNCTION OF XANTHINE OXIDOREDUCTASE: WHERE ARE WE NOW?.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 33. ISSUE 6. P. 774 -797 75 39% 383

Classes with closest relation at Level 1


Rank Class id link
1 23780 XANTHINE OXIDASE INHIBITOR//XANTHINE OXIDASE//XANTHINE OXIDASE INHIBITION
2 1607 MOLYBDENUM COFACTOR//MOLYBDOPTERIN//MOLYBDENUM COFACTOR DEFICIENCY
3 27533 PHARMACOKINET BIOANAL//HUMANIZED LIVER//PL DEV BIOL
4 19971 HYPOXANTHINE//OXYPURINOL//NUCLEOTIDE METABOLITES
5 27400 RENAL HYPOURICEMIA//HYPOURICEMIA//EXERCISE INDUCED ACUTE RENAL FAILURE
6 11851 MILK FAT GLOBULE MEMBRANE//MILK FAT GLOBULE//BUTYROPHILIN
7 34043 LOXOPROFEN//CS 670//PELUBIPROFEN
8 16471 HISTOCHEMICAL JOURNAL//FLUORESCENT FORMAZAN//MEMBRANE BOUND BODIES
9 2613 URIC ACID//HYPERURICEMIA//SERUM URIC ACID
10 8380 INTESTINAL ISCHEMIA REPERFUSION//INTESTINAL ISCHEMIA//LEUKOCYTE ENDOTHELIAL CELL ADHESION

Go to start page