Class information for:
Level 1: HYPOXANTHINE//OXYPURINOL//NUCLEOTIDE METABOLITES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19971 482 22.9 44%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
1752 2             LESCH NYHAN SYNDROME//AMP DEAMINASE//LESCH NYHAN DISEASE 6485
19971 1                   HYPOXANTHINE//OXYPURINOL//NUCLEOTIDE METABOLITES 482

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPOXANTHINE authKW 241437 9% 9% 43
2 OXYPURINOL authKW 205262 3% 20% 16
3 NUCLEOTIDE METABOLITES authKW 126701 0% 100% 2
4 XANTHINE authKW 105692 5% 6% 26
5 OXIPURINOL authKW 92141 1% 36% 4
6 2 8 DIHYDROXYPURINE authKW 63350 0% 100% 1
7 2 HYDROXYPURINE authKW 63350 0% 100% 1
8 ACTIVE METABOLITES BIOEQUIVALENCE authKW 63350 0% 100% 1
9 ADP RT authKW 63350 0% 100% 1
10 ADVERSE EFFECTS OF ALLOPURINOL authKW 63350 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medical Laboratory Technology 1211 9% 0% 41
2 Chemistry, Analytical 780 18% 0% 88
3 Pediatrics 532 12% 0% 59
4 Biochemical Research Methods 214 8% 0% 38
5 Pharmacology & Pharmacy 213 15% 0% 70
6 Endocrinology & Metabolism 197 9% 0% 43
7 Medicine, Research & Experimental 181 8% 0% 40
8 Obstetrics & Gynecology 146 6% 0% 29
9 Chemistry, Medicinal 55 4% 0% 19
10 Medicine, General & Internal 23 5% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MED PHYSIOPHATHOL 63350 0% 100% 1
2 SANIN ROSAI HOSP 63350 0% 100% 1
3 SERV RECUPERO RIEDUC FUNZ 63350 0% 100% 1
4 THORAX CARDIOCHEM POB 1738 63350 0% 100% 1
5 UNIDAD TRASTORNOS PIRATORIOS SUENO 63350 0% 100% 1
6 THORAC CARDIAC SURG UNIT 31674 0% 50% 1
7 MED HLTH SCI SURG 15836 0% 25% 1
8 NEPHROL CLIN PHARMACOL HYPERTENS 12668 0% 20% 1
9 UNIDAD MED QUIRURG ENFERMEDADES PIRATORIAS 12668 0% 20% 1
10 VCU MED 7915 0% 6% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METABOLISM-CLINICAL AND EXPERIMENTAL 5590 6% 0% 28
2 CANADIAN JOURNAL OF MEDICAL TECHNOLOGY 3958 0% 6% 1
3 JOURNAL OF PERINATAL MEDICINE 3175 2% 0% 12
4 JOURNAL OF LIQUID CHROMATOGRAPHY 3007 3% 0% 13
5 INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 1612 2% 0% 10
6 ANALYTICAL LETTERS PART B-CLINICAL AND BIOCHEMICAL ANALYSIS 1371 1% 1% 3
7 MEDICINA-RIVISTA DELLA ENCICLOPEDIA MEDICA ITALIANA 1337 0% 1% 2
8 CLINICA CHIMICA ACTA 1273 3% 0% 15
9 JOURNAL OF CHROMATOGRAPHY 1219 4% 0% 19
10 NUTRITION AND METABOLISM 1109 0% 2% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HYPOXANTHINE 241437 9% 9% 43 Search HYPOXANTHINE Search HYPOXANTHINE
2 OXYPURINOL 205262 3% 20% 16 Search OXYPURINOL Search OXYPURINOL
3 NUCLEOTIDE METABOLITES 126701 0% 100% 2 Search NUCLEOTIDE+METABOLITES Search NUCLEOTIDE+METABOLITES
4 XANTHINE 105692 5% 6% 26 Search XANTHINE Search XANTHINE
5 OXIPURINOL 92141 1% 36% 4 Search OXIPURINOL Search OXIPURINOL
6 2 8 DIHYDROXYPURINE 63350 0% 100% 1 Search 2+8+DIHYDROXYPURINE Search 2+8+DIHYDROXYPURINE
7 2 HYDROXYPURINE 63350 0% 100% 1 Search 2+HYDROXYPURINE Search 2+HYDROXYPURINE
8 ACTIVE METABOLITES BIOEQUIVALENCE 63350 0% 100% 1 Search ACTIVE+METABOLITES+BIOEQUIVALENCE Search ACTIVE+METABOLITES+BIOEQUIVALENCE
9 ADP RT 63350 0% 100% 1 Search ADP+RT Search ADP+RT
10 ADVERSE EFFECTS OF ALLOPURINOL 63350 0% 100% 1 Search ADVERSE+EFFECTS+OF+ALLOPURINOL Search ADVERSE+EFFECTS+OF+ALLOPURINOL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SAUGSTAD, OD , (1988) HYPOXANTHINE AS AN INDICATOR OF HYPOXIA - ITS ROLE IN HEALTH AND DISEASE THROUGH FREE-RADICAL PRODUCTION.PEDIATRIC RESEARCH. VOL. 23. ISSUE 2. P. 143-150 34 58% 218
2 KASAWAR, G , RAZZAK, M , ZAHEER, Z , FAROOQUI, M , (2011) VALIDATED RP-LC-MS/MS METHOD FOR THE SIMULTANEOUS DETERMINATION OF ALLOPURINOL AND ITS MAJOR METABOLITE, OXYPURINOL, IN HUMAN PLASMA.JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. VOL. 34. ISSUE 1. P. 26 -37 10 83% 1
3 YAMAMOTO, T , KOYAMA, H , KURAJOH, M , SHOJI, T , TSUTSUMI, Z , MORIWAKI, Y , (2011) BIOCHEMISTRY OF URIDINE IN PLASMA.CLINICA CHIMICA ACTA. VOL. 412. ISSUE 19-20. P. 1712 -1724 27 29% 14
4 YAMAMOTO, T , MORIWAKI, Y , TAKAHASHI, S , TSUTSUMI, Z , KA, T , FUKUCHI, M , HADA, T , (2002) EFFECT OF BEER ON THE PLASMA CONCENTRATIONS OF URIDINE AND PURINE BASES.METABOLISM-CLINICAL AND EXPERIMENTAL. VOL. 51. ISSUE 10. P. 1317-1323 11 92% 18
5 LIU, X , NI, XJ , SHANG, DW , ZHANG, M , HU, JQ , QIU, C , LUO, FT , WEN, YG , (2013) DETERMINATION OF ALLOPURINOL AND OXYPURINOL IN HUMAN PLASMA AND URINE BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 941. ISSUE . P. 10-16 9 82% 1
6 HARKNESS, RA , SAUGSTAD, OD , (1997) THE IMPORTANCE OF THE MEASUREMENT OF ATP DEPLETION AND SUBSEQUENT CELL DAMAGE WITH AN ESTIMATE OF SIZE AND NATURE OF THE MARKET FOR A PRACTICABLE METHOD: A REVIEW DESIGNED FOR TECHNOLOGY TRANSFER.SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. VOL. 57. ISSUE 8. P. 655 -672 33 34% 19
7 SCHMIDT, H , SIEMS, WG , GRUNE, T , GRAUEL, EL , (1995) CONCENTRATION OF PURINE COMPOUNDS IN THE CEREBROSPINAL-FLUID OF INFANTS SUFFERING FROM SEPSIS, CONVULSIONS AND HYDROCEPHALUS.JOURNAL OF PERINATAL MEDICINE. VOL. 23. ISSUE 3. P. 167-174 21 57% 20
8 KA, T , MORIWAKI, Y , INOKUCHI, T , YAMAMOTO, A , TAKAHASHI, S , TSUTSUMI, Z , YAMAMOTO, T , (2006) EFFECTS OF ALLOPURINOL ON BEER-INDUCED INCREASES IN PLASMA CONCENTRATIONS AND URINARY EXCRETION OF PURINE BASES (URIC ACID, HYPOXANTHINE, AND XANTHINE).HORMONE AND METABOLIC RESEARCH. VOL. 38. ISSUE 3. P. 188-192 9 90% 3
9 CASTROGAGO, M , RODRIGUEZSEGADE, S , DARRIBA, FC , FERNANDEZ, EC , PUNAL, JE , BELINCHON, PP , RODRIGUEZNUNEZ, A , (1996) CEREBROSPINAL FLUID PURINE METABOLITES AFTER COMPLEX FEBRILE CONVULSIONS.CHILDS NERVOUS SYSTEM. VOL. 12. ISSUE 6. P. 315-317 12 92% 2
10 YAMAMOTO, T , MORIWAKI, Y , TAKAHASHI, S , TSUTSUMI, Z , KA, T , HADA, T , (2002) EFFECT OF OCTREOTIDE ACETATE ON THE PLASMA CONCENTRATION AND URINARY EXCRETION OF URIDINE AND PURINE BASES.ENDOCRINE JOURNAL. VOL. 49. ISSUE 2. P. 139-144 13 68% 1

Classes with closest relation at Level 1


Rank Class id link
1 16843 PARTITION ADSORPTION SYSTEMS//3 4 DIMETHOXYPHENYLGLYOXAL//RAT RETICULOCYTES
2 24702 XANTHINE//HYPOXANTHINE//XANTHINE BIOSENSOR
3 32029 APRT DEFICIENCY//ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY//2 8 DIHYDROXYADENINE
4 34074 ALLANTOIN//ECHINOISOFLAVANONE//SOPHORA CHRYSOPHYLLA SEEM
5 27400 RENAL HYPOURICEMIA//HYPOURICEMIA//EXERCISE INDUCED ACUTE RENAL FAILURE
6 14850 AMP DEAMINASE//MYOADENYLATE DEAMINASE DEFICIENCY//PURINE NUCLEOTIDE CYCLE
7 1775 GOUT//FEBUXOSTAT//HYPERURICEMIA
8 21436 RAT HEART FUNCTION//D RIBOSE//AMP BREAKDOWN
9 33919 4 PYRIDONE 3 CARBOXAMIDE 1 BETA D RIBONUCLEOSIDE 4PYR//PCNR//4PYR
10 15139 LESCH NYHAN SYNDROME//LESCH NYHAN DISEASE//LESCH NYHAN

Go to start page