Class information for:
Level 1: XANTHINE OXIDASE INHIBITOR//XANTHINE OXIDASE//XANTHINE OXIDASE INHIBITION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23780 335 30.1 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
613 3       GOUT//HYPERURICEMIA//URIC ACID 14056
1622 2             GOUT//HYPERURICEMIA//URIC ACID 7034
23780 1                   XANTHINE OXIDASE INHIBITOR//XANTHINE OXIDASE//XANTHINE OXIDASE INHIBITION 335

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 XANTHINE OXIDASE INHIBITOR authKW 946208 10% 30% 35
2 XANTHINE OXIDASE authKW 732011 32% 7% 108
3 XANTHINE OXIDASE INHIBITION authKW 380094 4% 30% 14
4 NON PURINE XANTHINE OXIDASE INHIBITORS authKW 364599 1% 100% 4
5 ACACIA CONFUSA authKW 354729 4% 32% 12
6 ASTER GLEHNI authKW 273449 1% 100% 3
7 PHARMACEUT TECHNOL BIOTECHNOL PTBT address 182299 1% 100% 2
8 XO INHIBITOR authKW 182299 1% 100% 2
9 8 AZAXANTHINE authKW 164067 1% 60% 3
10 HIGH THROUGHPUT SCREENING BIOTECHNOL address 164067 1% 60% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 4016 33% 0% 109
2 Integrative & Complementary Medicine 2159 10% 0% 33
3 Pharmacology & Pharmacy 734 29% 0% 96
4 Chemistry, Organic 478 18% 0% 61
5 Plant Sciences 183 12% 0% 39
6 Food Science & Technology 172 9% 0% 31
7 Chemistry, Applied 144 7% 0% 23
8 Biochemistry & Molecular Biology 80 17% 0% 57
9 Chemistry, Multidisciplinary 57 11% 0% 38
10 Agricultural Engineering 55 2% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT TECHNOL BIOTECHNOL PTBT 182299 1% 100% 2
2 HIGH THROUGHPUT SCREENING BIOTECHNOL 164067 1% 60% 3
3 PLANTAS MED 119926 1% 26% 5
4 BIOQUIM 1B 91150 0% 100% 1
5 BOTUCATU MEDIAL 91150 0% 100% 1
6 DEV CHINESE MED ZHEJIANG PROV 91150 0% 100% 1
7 DRUG DISCOVERY DEVKITA KU 91150 0% 100% 1
8 MAHAJANA LIFE SCI MAHAJANA FDN 91150 0% 100% 1
9 MARINE ECON JIANGSU 91150 0% 100% 1
10 S 1NISHI KU 91150 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2287 2% 0% 7
2 JOURNAL OF ETHNOPHARMACOLOGY 2031 4% 0% 15
3 PHARMACEUTICAL BIOLOGY 1048 2% 0% 6
4 PHARMACOGNOSY MAGAZINE 877 1% 0% 3
5 FRONTIERS IN LIFE SCIENCE 777 0% 1% 1
6 IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH 740 1% 0% 3
7 ANTICANCER RESEARCH 671 4% 0% 12
8 INFLAMMOPHARMACOLOGY 659 0% 1% 1
9 PLANTA MEDICA 630 2% 0% 7
10 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 614 2% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 XANTHINE OXIDASE INHIBITOR 946208 10% 30% 35 Search XANTHINE+OXIDASE+INHIBITOR Search XANTHINE+OXIDASE+INHIBITOR
2 XANTHINE OXIDASE 732011 32% 7% 108 Search XANTHINE+OXIDASE Search XANTHINE+OXIDASE
3 XANTHINE OXIDASE INHIBITION 380094 4% 30% 14 Search XANTHINE+OXIDASE+INHIBITION Search XANTHINE+OXIDASE+INHIBITION
4 NON PURINE XANTHINE OXIDASE INHIBITORS 364599 1% 100% 4 Search NON+PURINE+XANTHINE+OXIDASE+INHIBITORS Search NON+PURINE+XANTHINE+OXIDASE+INHIBITORS
5 ACACIA CONFUSA 354729 4% 32% 12 Search ACACIA+CONFUSA Search ACACIA+CONFUSA
6 ASTER GLEHNI 273449 1% 100% 3 Search ASTER+GLEHNI Search ASTER+GLEHNI
7 XO INHIBITOR 182299 1% 100% 2 Search XO+INHIBITOR Search XO+INHIBITOR
8 8 AZAXANTHINE 164067 1% 60% 3 Search 8+AZAXANTHINE Search 8+AZAXANTHINE
9 MELANOXETIN 164067 1% 60% 3 Search MELANOXETIN Search MELANOXETIN
10 CHRYSANTHEMUM SINENSE 121532 1% 67% 2 Search CHRYSANTHEMUM+SINENSE Search CHRYSANTHEMUM+SINENSE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CHEN, SL , ZHANG, TJ , WANG, J , WANG, FY , NIU, HD , WU, CF , WANG, SJ , (2015) SYNTHESIS AND EVALUATION OF 1-HYDROXY/METHOXY-4-METHYL-2-PHENYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID DERIVATIVES AS NON-PURINE XANTHINE OXIDASE INHIBITORS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 103. ISSUE . P. 343 -353 17 68% 4
2 KUMAR, R , DARPAN, SS , SINGH, R , (2011) XANTHINE OXIDASE INHIBITORS: A PATENT SURVEY.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 21. ISSUE 7. P. 1071 -1108 27 47% 18
3 SATHISHA, KR , GOPAL, S , RANGAPPA, KS , (2016) ANTIHYPERURICEMIC EFFECTS OF THIADIAZOLOPYRIMIDIN-5-ONE ANALOGUES IN OXONATE TREATED RATS.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 776. ISSUE . P. 99 -105 18 46% 1
4 LING, X , BOCHU, W , (2014) A REVIEW OF PHYTOTHERAPY OF GOUT: PERSPECTIVE OF NEW PHARMACOLOGICAL TREATMENTS.PHARMAZIE. VOL. 69. ISSUE 4. P. 243 -256 24 35% 3
5 WANG, WL , SHEU, SY , HUANG, WD , CHUANG, YL , TSENG, HC , HWANG, TS , FU, YT , KUO, YH , YAO, CH , KUO, TF , (2016) PHYTOCHEMICALS FROM TRADESCANTIA ALBIFLORA KUNTH EXTRACTS REDUCE SERUM URIC ACID LEVELS IN OXONATE-INDUCED RATS.PHARMACOGNOSY MAGAZINE. VOL. 12. ISSUE 46. P. S223 -S227 11 73% 0
6 B-RAO, C , KULKARNI-ALMEIDA, A , KATKAR, KV , KHANNA, S , GHOSH, U , KECHE, A , SHAH, P , SRIVASTAVA, A , KORDE, V , NEMMANI, KVS , ET AL (2012) IDENTIFICATION OF NOVEL ISOCYTOSINE DERIVATIVES AS XANTHINE OXIDASE INHIBITORS FROM A SET OF VIRTUAL SCREENING HITS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 20. ISSUE 9. P. 2930-2939 17 49% 5
7 ALI, MR , KUMAR, S , AFZAL, O , SHALMALI, N , SHARMA, M , BAWA, S , (2016) DEVELOPMENT OF 2-(SUBSTITUTED BENZYLAMINO)-4-METHYL-1, 3-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AS XANTHINE OXIDASE INHIBITORS AND FREE RADICAL SCAVENGERS.CHEMICAL BIOLOGY & DRUG DESIGN. VOL. 87. ISSUE 4. P. 508 -516 15 47% 1
8 SHI, DH , HUANG, W , LI, C , LIU, YW , WANG, SF , (2014) DESIGN, SYNTHESIS AND MOLECULAR MODELING OF ALOE-EMODIN DERIVATIVES AS POTENT XANTHINE OXIDASE INHIBITORS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 75. ISSUE . P. 289 -296 13 59% 3
9 SUN, ZG , ZHOU, XJ , ZHU, ML , DING, WZ , LI, Z , ZHU, HL , (2015) SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL ARYL-2H-PYRAZOLE DERIVATIVES AS POTENT NON-PURINE XANTHINE OXIDASE INHIBITORS.CHEMICAL & PHARMACEUTICAL BULLETIN. VOL. 63. ISSUE 8. P. 603 -607 11 65% 1
10 DHIMAN, R , SHARMA, S , SINGH, G , NEPALI, K , BEDI, PMS , (2013) DESIGN AND SYNTHESIS OF AZA-FLAVONES AS A NEW CLASS OF XANTHINE OXIDASE INHIBITORS.ARCHIV DER PHARMAZIE. VOL. 346. ISSUE 1. P. 7 -16 13 50% 14

Classes with closest relation at Level 1


Rank Class id link
1 13862 ALDEHYDE OXIDASE//XANTHINE DEHYDROGENASE//XANTHINE OXIDOREDUCTASE
2 1775 GOUT//FEBUXOSTAT//HYPERURICEMIA
3 29952 BLUMEA BALSAMIFERA//PIPER BETLE//ALLYLPYROCATECHOL
4 21105 HIGH RESOLUTION SCREENING//ULTRAFILTRATION LC MS//LIGAND FISHING
5 1607 MOLYBDENUM COFACTOR//MOLYBDOPTERIN//MOLYBDENUM COFACTOR DEFICIENCY
6 20926 A1 ADENOSINE RECEPTOR LIGANDS//1 2 3 TRIAZOLO4 5 DPYRIMIDINES//2 ARYLSPIRO3 1 BENZOXAZINE 4 1 CYCLOPENTANES
7 37002 EMPTY PODS//ACACIA NILOTICA//ACACIA NILOTICA L
8 30305 COROSOLIC ACID//LAGERSTROEMIA SPECIOSA//BANABA
9 29371 BETA ACETAMIDO KETONES//DAKIN WEST REACTION//BETA AMIDO KETONES
10 30031 CIENCIAS EXACTASCCT LA PLATACONICET//6 FORMYLPTERIN//QUIMCCT LA PLATA CONICET

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