Class information for:
Level 1: SECT PHARMACOKINET//BOF 4272//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12791 880 30.8 50%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1171 2             JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM 9352
12791 1                   SECT PHARMACOKINET//BOF 4272//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 880

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT PHARMACOKINET address 356230 3% 38% 27
2 BOF 4272 authKW 246738 1% 89% 8
3 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS journal 237847 8% 10% 71
4 DIFFUSIONAL GRADIENTS authKW 138791 0% 100% 4
5 HEPATIC ELIMINATION authKW 113339 1% 47% 7
6 LOCAL DISPOSITION authKW 104093 0% 100% 3
7 NARUTO DRUG METAB address 104093 0% 100% 3
8 NONEQUILIBRIUM BINDING authKW 104093 0% 100% 3
9 MULTIPLE INDICATOR DILUTION authKW 102038 1% 29% 10
10 MULTIFILT authKW 78069 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 12444 68% 0% 600
2 Physiology 756 11% 0% 96
3 Chemistry, Medicinal 602 8% 0% 74
4 Gastroenterology & Hepatology 473 8% 0% 68
5 Toxicology 229 6% 0% 49
6 Chemistry, Multidisciplinary 146 11% 0% 99
7 Mathematical & Computational Biology 101 2% 0% 20
8 Biology 73 3% 0% 29
9 Medicine, Research & Experimental 21 3% 0% 27
10 Biochemical Research Methods 5 2% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT PHARMACOKINET 356230 3% 38% 27
2 NARUTO DRUG METAB 104093 0% 100% 3
3 NARUTO 55093 1% 18% 9
4 MARY BETH DONNELLEY CLIN PHARMACOL CORE IL 46258 0% 33% 4
5 AARON M R P ORT MICROCIRCULAT 34698 0% 100% 1
6 ANDRE VIALLET CLIN 264 E RENE LEVESQUE 34698 0% 100% 1
7 HESTOPERAT TECHNOL BRANCH 34698 0% 100% 1
8 HLTH SCIBASIL HETZEL MED 34698 0% 100% 1
9 INSERM U181 34698 0% 100% 1
10 MED CHEM ENGN PL CHEM 34698 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 237847 8% 10% 71
2 DRUG METABOLISM AND DISPOSITION 18311 7% 1% 63
3 JOURNAL OF PHARMACEUTICAL SCIENCES 7694 6% 0% 50
4 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 7345 8% 0% 67
5 JOURNAL OF PHARMACOBIO-DYNAMICS 6874 2% 1% 18
6 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 5881 1% 2% 10
7 JOURNAL OF PHARMACY AND PHARMACOLOGY 5580 4% 0% 36
8 BIOCHEMICAL PHARMACOLOGY 4832 6% 0% 51
9 AMERICAN JOURNAL OF PHYSIOLOGY 3456 6% 0% 50
10 PHARMACEUTICAL RESEARCH 3364 3% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BOF 4272 246738 1% 89% 8 Search BOF+4272 Search BOF+4272
2 DIFFUSIONAL GRADIENTS 138791 0% 100% 4 Search DIFFUSIONAL+GRADIENTS Search DIFFUSIONAL+GRADIENTS
3 HEPATIC ELIMINATION 113339 1% 47% 7 Search HEPATIC+ELIMINATION Search HEPATIC+ELIMINATION
4 LOCAL DISPOSITION 104093 0% 100% 3 Search LOCAL+DISPOSITION Search LOCAL+DISPOSITION
5 NONEQUILIBRIUM BINDING 104093 0% 100% 3 Search NONEQUILIBRIUM+BINDING Search NONEQUILIBRIUM+BINDING
6 MULTIPLE INDICATOR DILUTION 102038 1% 29% 10 Search MULTIPLE+INDICATOR+DILUTION Search MULTIPLE+INDICATOR+DILUTION
7 MULTIFILT 78069 0% 75% 3 Search MULTIFILT Search MULTIFILT
8 2 COMPARTMENT DISPERSION MODEL 69396 0% 100% 2 Search 2+COMPARTMENT+DISPERSION+MODEL Search 2+COMPARTMENT+DISPERSION+MODEL
9 HEPATIC PHARMACOKINETICS 69396 0% 100% 2 Search HEPATIC+PHARMACOKINETICS Search HEPATIC+PHARMACOKINETICS
10 HEPATOCELLULAR DIFFUSION MODEL 69396 0% 100% 2 Search HEPATOCELLULAR+DIFFUSION+MODEL Search HEPATOCELLULAR+DIFFUSION+MODEL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PANG, KS , XIN, X , STPIERRE, MV , (1992) DETERMINANTS OF METABOLITE DISPOSITION.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 32. ISSUE . P. 623-669 56 67% 13
2 SAHIN, S , ROWLAND, M , (2007) APPLICATION OF THE DISPERSION MODEL TO DESCRIBE DISPOSITION KINETICS OF MARKERS IN THE DUAL PERFUSED RAT LIVER.DRUG METABOLISM AND DISPOSITION. VOL. 35. ISSUE 7. P. 1119 -1125 25 89% 1
3 STPIERRE, MV , LEE, PI , PANG, KS , (1992) A COMPARATIVE INVESTIGATION OF HEPATIC-CLEARANCE MODELS - PREDICTIONS OF METABOLITE FORMATION AND ELIMINATION.JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS. VOL. 20. ISSUE 2. P. 105-145 39 91% 8
4 ANISSIMOV, YG , ROBERTS, MS , (2002) A COMPARTMENTAL MODEL OF HEPATIC DISPOSITION KINETICS: 1. MODEL DEVELOPMENT AND APPLICATION TO LINEAR KINETICS.JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. VOL. 29. ISSUE 2. P. 131-156 26 93% 10
5 SCHWAB, AJ , GENG, WP , PANG, KS , (1998) APPLICATION OF THE DISPERSION MODEL FOR DESCRIPTION OF THE OUTFLOW DILUTION PROFILES OF NONELIMINATED REFERENCE INDICATORS IN RAT LIVER PERFUSION STUDIES.JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS. VOL. 26. ISSUE 2. P. 163 -181 35 78% 11
6 ROBERTS, MS , (2010) DRUG STRUCTURE-TRANSPORT RELATIONSHIPS.JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. VOL. 37. ISSUE 6. P. 541 -573 48 38% 0
7 WILKINSON, GR , (1987) CLEARANCE APPROACHES IN PHARMACOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 39. ISSUE 1. P. 1-47 80 35% 315
8 ROBERTS, MS , ANISSIMOV, YG , (1999) MODELING OF HEPATIC ELIMINATION AND ORGAN DISTRIBUTION KINETICS WITH THE EXTENDED CONVECTION-DISPERSION MODEL.JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS. VOL. 27. ISSUE 4. P. 343-382 29 78% 17
9 MELLICK, GD , ROBERTS, MS , (1997) IMPULSE-RESPONSE STUDIES ON TRACER DOSES OF [C-14]LIGNOCAINE AND ITS MULTIPLE METABOLITES IN THE PERFUSED RAT LIVER.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 49. ISSUE 10. P. 1008-1018 32 78% 0
10 SCHWAB, AJ , TAO, L , KANG, M , MENG, LJ , PANG, KS , (2003) MOMENT ANALYSIS OF METABOLIC HETEROGENEITY: CONJUGATION OF BENZOATE WITH GLYCINE IN RAT LIVER STUDIED BY MULTIPLE INDICATOR DILUTION TECHNIQUE.JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 305. ISSUE 1. P. 279-289 25 78% 2

Classes with closest relation at Level 1


Rank Class id link
1 10654 INTERSPECIES SCALING//VOLUME OF DISTRIBUTION//STEADY STATE VOLUME OF DISTRIBUTION
2 30098 ADRENAL GLAND CORTICOSTERONE//BIOCHEMICAL INDICATOR ANALYSIS//CARDIO GREEN
3 35824 INO 2628 CZ//EFFICIENCY OF ENTEROHEPATIC CIRCULATION//MNP001
4 14290 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//IVIVC//NONLINEAR COMPARTMENTAL MODEL
5 11094 METABOLIC ZONATION//LIVER ZONATION//HEPATOCYTE HETEROGENEITY
6 3044 ORGANIC ANIONS//CANALICULAR MEMBRANE//BILITRANSLOCASE
7 10401 MEGX//MONOETHYLGLYCINEXYLIDIDE//LIVER FUNCTION
8 30802 LIVER METAB//LIVER GLUCONEOGENESIS//GLYCEMIA RECOVERY
9 25772 CLOMETHIAZOLE//CHLORMETHIAZOLE//AR R008055
10 34996 ACTIVE CENTER ANALOGS OF SUPEROXIDE DISMUTASE//COFPLATON//COFPROPAMINE

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