Class information for:
Level 1: METABOLIC ZONATION//LIVER ZONATION//HEPATOCYTE HETEROGENEITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11094 1007 39.1 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
630 3       HEPATIC ENCEPHALOPATHY//ASYMMETRIC DIMETHYLARGININE//HYPERAMMONEMIA 13067
1445 2             HEPATIC ENCEPHALOPATHY//HYPERAMMONEMIA//MINIMAL HEPATIC ENCEPHALOPATHY 7828
11094 1                   METABOLIC ZONATION//LIVER ZONATION//HEPATOCYTE HETEROGENEITY 1007

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METABOLIC ZONATION authKW 594651 3% 63% 31
2 LIVER ZONATION authKW 163729 1% 60% 9
3 HEPATOCYTE HETEROGENEITY authKW 151608 0% 100% 5
4 HEPATIC ZONATION authKW 129256 1% 47% 9
5 BIVASCULAR LIVER PERFUSION authKW 123807 1% 58% 7
6 ENZYMATIC ZONATION authKW 121286 0% 100% 4
7 UNIT ROCQUENCOURT address 68222 0% 75% 3
8 VIRTUAL LIVER authKW 68222 0% 75% 3
9 ADRENALECTOMY FASTING DEXAMETHASONE authKW 60643 0% 100% 2
10 EXPT PATHOL EP address 60643 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Gastroenterology & Hepatology 2361 15% 0% 153
2 Cell Biology 2111 25% 0% 247
3 Biochemistry & Molecular Biology 852 27% 0% 273
4 Anatomy & Morphology 774 4% 0% 40
5 Biophysics 359 8% 0% 79
6 Toxicology 319 6% 0% 61
7 CYTOLOGY & HISTOLOGY 309 1% 0% 9
8 Pharmacology & Pharmacy 216 11% 0% 111
9 Microscopy 188 2% 0% 16
10 Pathology 65 3% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT ROCQUENCOURT 68222 0% 75% 3
2 EXPT PATHOL EP 60643 0% 100% 2
3 JACQUES LUIS LIONS 60643 0% 100% 2
4 MIRM LIVER 60643 0% 100% 2
5 SCI JOINT UNIT 7598 60643 0% 100% 2
6 UPCI GI ONCOL 60643 0% 100% 2
7 PHYS EXPT ONCOL 54576 0% 60% 3
8 BIOFLUID TISSUE SOLID MECH MED PLICAT BIOMMED 45479 0% 50% 3
9 DRUG DISPOSIT DOMAIN 40427 0% 67% 2
10 LIVER METAB 34576 1% 13% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HISTOCHEMISTRY 19547 4% 2% 40
2 RBC-CELL BIOLOGY REVIEWS 13854 0% 11% 4
3 HEPATOLOGY 13580 7% 1% 73
4 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 7499 4% 1% 38
5 PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY/BK SERIES 5700 0% 5% 4
6 EXPERIMENTAL PATHOLOGY 4950 1% 1% 11
7 FOLIA HISTOCHEMICA ET CYTOCHEMICA 3243 0% 4% 3
8 HISTOCHEMICAL JOURNAL 2911 1% 1% 14
9 ACTA HISTOCHEMICA ET CYTOCHEMICA 1665 1% 1% 10
10 EUROPEAN JOURNAL OF BIOCHEMISTRY 1624 3% 0% 33

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METABOLIC ZONATION 594651 3% 63% 31 Search METABOLIC+ZONATION Search METABOLIC+ZONATION
2 LIVER ZONATION 163729 1% 60% 9 Search LIVER+ZONATION Search LIVER+ZONATION
3 HEPATOCYTE HETEROGENEITY 151608 0% 100% 5 Search HEPATOCYTE+HETEROGENEITY Search HEPATOCYTE+HETEROGENEITY
4 HEPATIC ZONATION 129256 1% 47% 9 Search HEPATIC+ZONATION Search HEPATIC+ZONATION
5 BIVASCULAR LIVER PERFUSION 123807 1% 58% 7 Search BIVASCULAR+LIVER+PERFUSION Search BIVASCULAR+LIVER+PERFUSION
6 ENZYMATIC ZONATION 121286 0% 100% 4 Search ENZYMATIC+ZONATION Search ENZYMATIC+ZONATION
7 VIRTUAL LIVER 68222 0% 75% 3 Search VIRTUAL+LIVER Search VIRTUAL+LIVER
8 ADRENALECTOMY FASTING DEXAMETHASONE 60643 0% 100% 2 Search ADRENALECTOMY+FASTING+DEXAMETHASONE Search ADRENALECTOMY+FASTING+DEXAMETHASONE
9 INTRAACINAR PROFILES 60643 0% 100% 2 Search INTRAACINAR+PROFILES Search INTRAACINAR+PROFILES
10 U C 14LACTATE 60643 0% 100% 2 Search U+C+14LACTATE Search U+C+14LACTATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GEBHARDT, R , (1992) METABOLIC ZONATION OF THE LIVER - REGULATION AND IMPLICATIONS FOR LIVER-FUNCTION.PHARMACOLOGY & THERAPEUTICS. VOL. 53. ISSUE 3. P. 275-354 224 36% 271
2 JUNGERMANN, K , KATZ, N , (1989) FUNCTIONAL SPECIALIZATION OF DIFFERENT HEPATOCYTE POPULATIONS.PHYSIOLOGICAL REVIEWS. VOL. 69. ISSUE 3. P. 708-764 120 50% 466
3 GEBHARDT, R , BALDYSIAK-FIGIEL, A , KRUGEL, V , UEBERHAM, E , GAUNITZ, F , (2007) HEPATOCELLULAR EXPRESSION OF GLUTAMINE SYNTHETASE: AN INDICATOR OF MORPHOGEN ACTIONS AS MASTER REGULATORS OF ZONATION IN ADULT LIVER.PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY. VOL. 41. ISSUE 4. P. 201-266 114 41% 51
4 SCHLEICHER, J , TOKARSKI, C , MARBACH, E , MATZ-SOJA, M , ZELLMER, S , GEBHARDT, R , SCHUSTER, S , (2015) ZONATION OF HEPATIC FATTY ACID METABOLISM - THE DIVERSITY OF ITS REGULATION AND THE BENEFIT OF MODELING.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1851. ISSUE 5. P. 641 -656 79 34% 7
5 GEBHARDT, R , MATZ-SOJA, M , (2014) LIVER ZONATION: NOVEL ASPECTS OF ITS REGULATION AND ITS IMPACT ON HOMEOSTASIS.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 20. ISSUE 26. P. 8491 -8504 53 44% 17
6 BRAEUNING, A , SINGH, Y , RIGNALL, B , BUCHMANN, A , HAMMAD, S , OTHMAN, A , VON RECKLINGHAUSEN, I , GODOY, P , HOEHME, S , DRASDO, D , ET AL (2010) PHENOTYPE AND GROWTH BEHAVIOR OF RESIDUAL BETA-CATENIN-POSITIVE HEPATOCYTES IN LIVERS OF BETA-CATENIN-DEFICIENT MICE.HISTOCHEMISTRY AND CELL BIOLOGY. VOL. 134. ISSUE 5. P. 469-481 35 71% 11
7 JUNGERMANN, K , THURMAN, RG , (1992) HEPATOCYTE HETEROGENEITY IN THE METABOLISM OF CARBOHYDRATES.ENZYME. VOL. 46. ISSUE 1-3. P. 33-58 56 72% 74
8 BRAEUNING, A , SCHWARZ, M , (2010) BETA-CATENIN AS A MULTILAYER MODULATOR OF ZONAL CYTOCHROME P450 EXPRESSION IN MOUSE LIVER.BIOLOGICAL CHEMISTRY. VOL. 391. ISSUE 2-3. P. 139-148 35 65% 8
9 BRAEUNING, A , (2012) INTERPLAY OF BETA-CATENIN WITH XENOBIOTIC-SENSING RECEPTORS AND ITS ROLE IN GLUTATHIONE S-TRANSFERASE EXPRESSION.CURRENT DRUG METABOLISM. VOL. 13. ISSUE 2. P. 203-214 49 43% 1
10 KLINGER, W , DEVEREUX, T , FOUTS, JR , (1988) FUNCTIONAL AND STRUCTURAL ZONAL HEPATOCYTE HETEROGENEITY - DYNAMICS AND ONTOGENIC DEVELOPMENT.EXPERIMENTAL PATHOLOGY. VOL. 35. ISSUE 2. P. 69-91 69 64% 19

Classes with closest relation at Level 1


Rank Class id link
1 19398 UREA SYNTHESIS//HEPATIC AMINO NITROGEN CONVERSION//N ACETYLGLUTAMATE DEGRADATION
2 16471 HISTOCHEMICAL JOURNAL//FLUORESCENT FORMAZAN//MEMBRANE BOUND BODIES
3 12791 SECT PHARMACOKINET//BOF 4272//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS
4 35075 IN 111 WBC//ABDOMINAL INFLAMMATORY IMAGING//BLOOD GRANULOCYTE
5 30802 LIVER METAB//LIVER GLUCONEOGENESIS//GLYCEMIA RECOVERY
6 16379 HEPATIC INNERVATION//ABT BIOCHEM ERNAHRUNG//MODERN MED TECHNOL
7 10958 PHOSPHOENOLPYRUVATE CARBOXYKINASE//GLYCERONEOGENESIS//BROWN ADIPOSE TISSUE HEMIDENERVATION
8 34984 DEPTH VISUAL//KM MOUSE//ERIKSEN TASK
9 19272 LIVER MICRO UNIT ACTION//ALPHA2 MACROGLOBULIN GENE//090
10 1332 OVAL CELLS//HEPATIC PROGENITOR CELLS//HEPATIC DIFFERENTIATION

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