Class information for:
Level 1: CLOMETHIAZOLE//CHLORMETHIAZOLE//AR R008055

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25772 272 31.9 54%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1171 2             JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM 9352
25772 1                   CLOMETHIAZOLE//CHLORMETHIAZOLE//AR R008055 272

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLOMETHIAZOLE authKW 1207481 8% 51% 21
2 CHLORMETHIAZOLE authKW 1025160 8% 42% 22
3 AR R008055 authKW 224524 1% 100% 2
4 NMZ authKW 224524 1% 100% 2
5 CHLOMETHIAZOLE authKW 149681 1% 67% 2
6 5 2 F 18 FLUOROETHYL 4 METHYLTHIAZOLE authKW 112262 0% 100% 1
7 5 HT1A 5 HYDROXYTRYPTAMINE1A RECEPTOR authKW 112262 0% 100% 1
8 5 HYDROXYTRYPTAMINE MEDIATED BEHAVIOR authKW 112262 0% 100% 1
9 ALZHEIMERS DISEASE MODIFYING APPROACH authKW 112262 0% 100% 1
10 ANAESTHESIA NEUROINTENS CARE address 112262 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1907 49% 0% 133
2 Anesthesiology 1352 14% 0% 37
3 Neurosciences 142 15% 0% 42
4 Chemistry, Medicinal 71 6% 0% 15
5 Psychiatry 65 7% 0% 18
6 Cardiac & Cardiovascular System 44 6% 0% 17
7 Critical Care Medicine 25 2% 0% 6
8 Toxicology 19 3% 0% 9
9 Peripheral Vascular Diseases 15 3% 0% 8
10 Clinical Neurology 8 4% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANAESTHESIA NEUROINTENS CARE 112262 0% 100% 1
2 NEUROL MAUBEUGE 112262 0% 100% 1
3 MS RAMAIAH PHARM 56130 0% 50% 1
4 PHARMACEUT PRECLIN DEV 56130 0% 50% 1
5 PKPD SECT 37419 0% 33% 1
6 COMPARAT COGNIT TEAM 22449 1% 10% 2
7 DMPKBAC 14031 0% 13% 1
8 GRAZING ANIM PROD 11224 0% 10% 1
9 RD BOSTON 8634 0% 8% 1
10 TOXICOL DEV 5907 0% 5% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 5487 2% 1% 6
2 BRITISH JOURNAL OF ANAESTHESIA 4962 7% 0% 20
3 NEURODEGENERATION 2701 1% 1% 2
4 ACTA PSYCHIATRICA SCANDINAVICA 2235 4% 0% 11
5 ADVANCES IN PAIN RESEARCH AND THERAPY 1600 1% 0% 3
6 BIOPHARMACEUTICS & DRUG DISPOSITION 1450 2% 0% 5
7 JOURNAL OF PHARMACEUTICAL SCIENCES 1198 4% 0% 11
8 BRITISH JOURNAL OF PHARMACOLOGY 897 4% 0% 12
9 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 875 3% 0% 8
10 ANAESTHESIA AND INTENSIVE CARE 780 2% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CLOMETHIAZOLE 1207481 8% 51% 21 Search CLOMETHIAZOLE Search CLOMETHIAZOLE
2 CHLORMETHIAZOLE 1025160 8% 42% 22 Search CHLORMETHIAZOLE Search CHLORMETHIAZOLE
3 AR R008055 224524 1% 100% 2 Search AR+R008055 Search AR+R008055
4 NMZ 224524 1% 100% 2 Search NMZ Search NMZ
5 CHLOMETHIAZOLE 149681 1% 67% 2 Search CHLOMETHIAZOLE Search CHLOMETHIAZOLE
6 5 2 F 18 FLUOROETHYL 4 METHYLTHIAZOLE 112262 0% 100% 1 Search 5+2+F+18+FLUOROETHYL+4+METHYLTHIAZOLE Search 5+2+F+18+FLUOROETHYL+4+METHYLTHIAZOLE
7 5 HT1A 5 HYDROXYTRYPTAMINE1A RECEPTOR 112262 0% 100% 1 Search 5+HT1A+5+HYDROXYTRYPTAMINE1A+RECEPTOR Search 5+HT1A+5+HYDROXYTRYPTAMINE1A+RECEPTOR
8 5 HYDROXYTRYPTAMINE MEDIATED BEHAVIOR 112262 0% 100% 1 Search 5+HYDROXYTRYPTAMINE+MEDIATED+BEHAVIOR Search 5+HYDROXYTRYPTAMINE+MEDIATED+BEHAVIOR
9 ALZHEIMERS DISEASE MODIFYING APPROACH 112262 0% 100% 1 Search ALZHEIMERS+DISEASE+MODIFYING+APPROACH Search ALZHEIMERS+DISEASE+MODIFYING+APPROACH
10 AR A008055 112262 0% 100% 1 Search AR+A008055 Search AR+A008055

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WILBY, MJ , HUTCHINSON, PJ , (2004) THE PHARMACOLOGY OF CHLORMETHIAZOLE: A POTENTIAL NEUROPROTECTIVE AGENT?.CNS DRUG REVIEWS. VOL. 10. ISSUE 4. P. 281-294 33 73% 20
2 VANDEVREDE, L , TAVASSOLI, E , LUO, J , QIN, ZH , YUE, L , PEPPERBERG, DR , THATCHER, GR , (2014) NOVEL ANALOGUES OF CHLORMETHIAZOLE ARE NEUROPROTECTIVE IN FOUR CELLULAR MODELS OF NEURODEGENERATION BY A MECHANISM WITH VARIABLE DEPENDENCE ON GABA(A) RECEPTOR POTENTIATION.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 171. ISSUE 2. P. 389-402 22 44% 6
3 FULTON, B , PARK, GR , (1993) INTRAVENOUS CHLORMETHIAZOLE.BRITISH JOURNAL OF HOSPITAL MEDICINE. VOL. 48. ISSUE 11. P. 742-747 21 81% 0
4 LIU, J , WANG, LN , MA, X , JI, XM , (2016) GAMMA AMINOBUTYRIC ACID (GABA) RECEPTOR AGONISTS FOR ACUTE STROKE.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 10. P. - 15 48% 1
5 GREEN, AR , MURRAY, TK , MISRA, A , SNAPE, MF , JONES, JA , CROSS, AJ , (2000) THE METABOLISM OF CLOMETHIAZOLE IN GERBILS AND THE NEUROPROTECTIVE AND SEDATIVE ACTIVITY OF THE METABOLITES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 129. ISSUE 1. P. 95-100 11 85% 5
6 LIU, J , WANG, LN , (2013) GAMMA AMINOBUTYRIC ACID (GABA) RECEPTOR AGONISTS FOR ACUTE STROKE.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 2. P. - 13 46% 6
7 LIU, J , WANG, LN , (2014) GAMMA AMINOBUTYRIC ACID (GABA) RECEPTOR AGONISTS FOR ACUTE STROKE.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 8. P. - 13 46% 0
8 QJN, ZH , LUO, J , VANDEVREDE, L , TAVASSOLI, E , FA', M , TEICH, AF , ARANCIO, O , THATCHER, GRJ , (2012) DESIGN AND SYNTHESIS OF NEUROPROTECTIVE METHYLTHIAZOLES AND MODIFICATION AS NO-CHIMERAS FOR NEURODEGENERATIVE THERAPY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 55. ISSUE 15. P. 6784 -6801 22 29% 1
9 UPTON, RN , ZHENG, DA , GRANT, C , MARTINEZ, AM , (2000) DEVELOPMENT AND VALIDATION OF A RECIRCULATORY PHYSIOLOGICAL MODEL OF THE MYOCARDIAL CONCENTRATIONS OF LIGNOCAINE AFTER INTRAVENOUS ADMINISTRATION IN SHEEP.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 52. ISSUE 2. P. 181 -189 14 54% 3
10 VILCHEZ, JJ , LAGO, A , BURGUERA, JA , YAYA, R , CASANOVA, V , (1994) CHLORMETHIAZOLE IN THE MANAGEMENT OF THE OPSOCLONUS-MYOCLONUS SYNDROME.JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. VOL. 22. ISSUE 1. P. 55-62 14 67% 4

Classes with closest relation at Level 1


Rank Class id link
1 22494 CAS 76 75 5//THIOPENTAL//THIAZOLO3 2 A1 3DIAZEPINE
2 30362 COMPLICATIONS NORPETHIDINE TOXICITY//OPIOIDS PETHIDINE//PETHIDINE HYDROCHLORIDE
3 4833 DELAYED NEURONAL DEATH//GERBIL//CEREBRAL ISCHEMIA
4 10889 LUBELUZOLE//NIMODIPINE//LEVEMOPAMIL
5 12791 SECT PHARMACOKINET//BOF 4272//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS
6 16038 LUNG METABOLIC FUNCTION//LUNG DRUG UPTAKE//PULMONARY CAPILLARY ENDOTHELIUM
7 18680 NXY 059//PBN//ALPHA PHENYL N TERT BUTYL NITRONE
8 33117 PERICARDIAL FLUID//ALEXANDRA STATE UNIV HOSP//EPICARDIAL DRUG DELIVERY
9 6342 ROPIVACAINE//BUPIVACAINE//LEVOBUPIVACAINE
10 10854 ALCOHOL WITHDRAWAL//ALCOHOL WITHDRAWAL SYNDROME//DELIRIUM TREMENS

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