Class information for:
Level 1: KW 2149//MITOSENE//FR900482

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12399 908 32.0 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
1363 2             TIRAPAZAMINE//DT DIAPHORASE//BIOREDUCTIVE DRUGS 8244
12399 1                   KW 2149//MITOSENE//FR900482 908

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KW 2149 authKW 539911 2% 94% 17
2 MITOSENE authKW 247619 1% 82% 9
3 FR900482 authKW 239129 1% 89% 8
4 MITOMYCIN C authKW 216621 12% 6% 108
5 PORFIROMYCIN authKW 205968 1% 88% 7
6 FK317 authKW 201767 1% 100% 6
7 AZIRIDINOMITOSENE authKW 140114 1% 83% 5
8 2 7 DIAMINOMITOSENE authKW 134511 0% 100% 4
9 FK973 authKW 134511 0% 100% 4
10 MITOMYCINS authKW 117690 1% 50% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 2105 23% 0% 206
2 Oncology 1397 22% 0% 197
3 Chemistry, Medicinal 1246 12% 0% 105
4 Pharmacology & Pharmacy 833 20% 0% 178
5 Chemistry, Multidisciplinary 487 17% 0% 158
6 Toxicology 76 4% 0% 32
7 Biochemistry & Molecular Biology 60 12% 0% 105
8 Chemistry, Analytical 43 5% 0% 41
9 Crystallography 25 2% 0% 19
10 CYTOLOGY & HISTOLOGY 14 0% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THER EUT RADIOL DEV THER EUT PROGRAM 67256 0% 100% 2
2 BIOMOLEC STRUCT FUNCT BIOL SCI 33628 0% 100% 1
3 ITSUU 22810 TAMAGAWA SETAGAYA KU 33628 0% 100% 1
4 IU MOL STRUCT 33628 0% 100% 1
5 JOHN HAY 33628 0% 100% 1
6 MED CHEM CHEM MICROBIOL IMMUNOBIOL 33628 0% 100% 1
7 MED COMPREHENS CANCDEV THER EUT PROGRAM 33628 0% 100% 1
8 MED ONCOLDUKE CANC 33628 0% 100% 1
9 RADIO ORTHOPED REHABILITAT SCI 33628 0% 100% 1
10 RICHARD LEWIS EXCELLENCE 33628 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER COMMUNICATIONS 5267 0% 4% 4
2 JOURNAL OF ORGANIC CHEMISTRY 2968 7% 0% 68
3 CANCER CHEMOTHERAPY AND PHARMACOLOGY 2185 2% 0% 22
4 JOURNAL OF MEDICINAL CHEMISTRY 2095 4% 0% 37
5 CANCER RESEARCH 2092 6% 0% 50
6 JOURNAL OF ANTIBIOTICS 1795 2% 0% 19
7 CHEMICAL RESEARCH IN TOXICOLOGY 1431 2% 0% 15
8 ADVANCES IN ENZYME REGULATION 1401 1% 1% 5
9 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 1233 7% 0% 60
10 BIOCHEMICAL PHARMACOLOGY 1191 3% 0% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 KW 2149 539911 2% 94% 17 Search KW+2149 Search KW+2149
2 MITOSENE 247619 1% 82% 9 Search MITOSENE Search MITOSENE
3 FR900482 239129 1% 89% 8 Search FR900482 Search FR900482
4 MITOMYCIN C 216621 12% 6% 108 Search MITOMYCIN+C Search MITOMYCIN+C
5 PORFIROMYCIN 205968 1% 88% 7 Search PORFIROMYCIN Search PORFIROMYCIN
6 FK317 201767 1% 100% 6 Search FK317 Search FK317
7 AZIRIDINOMITOSENE 140114 1% 83% 5 Search AZIRIDINOMITOSENE Search AZIRIDINOMITOSENE
8 2 7 DIAMINOMITOSENE 134511 0% 100% 4 Search 2+7+DIAMINOMITOSENE Search 2+7+DIAMINOMITOSENE
9 FK973 134511 0% 100% 4 Search FK973 Search FK973
10 MITOMYCINS 117690 1% 50% 7 Search MITOMYCINS Search MITOMYCINS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BASS, PD , GUBLER, DA , JUDD, TC , WILLIAMS, RM , (2013) MITOMYCINOID ALKALOIDS: MECHANISM OF ACTION, BIOSYNTHESIS, TOTAL SYNTHESES, AND SYNTHETIC APPROACHES.CHEMICAL REVIEWS. VOL. 113. ISSUE 8. P. 6816-6863 178 70% 33
2 WIEDNER, SD , VEDEJS, E , (2012) REACTIVITY OF AZIRIDINOMITOSENE DERIVATIVES RELATED TO FK317 IN THE PRESENCE OF PROTIC NUCLEOPHILES.JOURNAL OF ORGANIC CHEMISTRY. VOL. 77. ISSUE 2. P. 1045 -1055 42 79% 1
3 TOMASZ, M , PALOM, Y , (1997) THE MITOMYCIN BIOREDUCTIVE ANTITUMOR AGENTS: CROSS-LINKING AND ALKYLATION OF DNA AS THE MOLECULAR BASIS OF THEIR ACTIVITY.PHARMACOLOGY & THERAPEUTICS. VOL. 76. ISSUE 1-3. P. 73 -87 57 70% 148
4 WILLIAMS, RM , DUCEPT, P , (2003) INTERSTRAND CROSS-LINKING OF DNA BY FK317 AND ITS DEACETYLATED METABOLITES FR70496 AND FR157471.BIOCHEMISTRY. VOL. 42. ISSUE 49. P. 14696-14701 40 95% 9
5 ANDREZ, JC , (2009) MITOMYCINS SYNTHESES: A RECENT UPDATE.BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. VOL. 5. ISSUE . P. - 62 50% 20
6 DUCRAY, R , CIUFOLINI, MA , (2002) TOTAL SYNTHESIS OF (+/-)-FR66979.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 41. ISSUE 24. P. 4688 -4691 44 85% 37
7 KIM, M , VEDEJS, E , (2004) A SYNTHETIC APPROACH TOWARD THE PROPOSED TETRACYCLIC AZIRIDINOMITOSENE DERIVED FROM FK317.JOURNAL OF ORGANIC CHEMISTRY. VOL. 69. ISSUE 21. P. 7262 -7265 49 73% 18
8 JUDD, TC , WILLIAMS, RM , (2002) SYNTHESIS AND DNA CROSS-LINKING OF A PHOTOTRIGGERED FR900482 MITOSENE PROGENITOR.ORGANIC LETTERS. VOL. 4. ISSUE 21. P. 3711-3714 43 88% 18
9 JUDD, TC , WILLIAMS, RM , (2004) A CONCISE TOTAL SYNTHESIS OF (+)-FR900482 AND (+)-FR66979.JOURNAL OF ORGANIC CHEMISTRY. VOL. 69. ISSUE 8. P. 2825 -2830 54 65% 11
10 JUDD, TC , WILLIAMS, RM , (2002) CONCISE ENANTIOSELECTIVE SYNTHESIS OF (+)-FR66979 AND (+)-FR900482: DIMETHYLDIOXIRANE-MEDIATED CONSTRUCTION OF THE HYDROXYLAMINE HEMIKETAL.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 41. ISSUE 24. P. 4683 -4685 46 77% 44

Classes with closest relation at Level 1


Rank Class id link
1 7463 NQO1//DT DIAPHORASE//EO9
2 22766 ANTHRAQUINONE DISULPHONATES//NAA UNIT//SOLVENT POLARITY EFFECT
3 28594 AZINOMYCIN//1 3 DIAZABICYCLO310HEX 3 ENE//CARZINOPHILIN
4 15678 TIRAPAZAMINE//BIOREDUCTIVE DRUGS//SR 4233
5 31903 YUEHCHUKENE//INTRAMOLECULAR ALKYL MIGRATION//INDOLYLCUPRATE
6 15753 QUINONE METHIDE//O QUINONE METHIDE//ORTHO QUINONE METHIDE
7 22482 TERT AMINO EFFECT//1 5 HYDRIDE TRANSFER//ORGAN SYNTH TECHNOL
8 31765 PHARMACEUT SCI BUNKYO MACHI 114//SELECTED ANTIBODY ENZYME IMMUNOASSAY//CELL BIOL IBHV
9 32586 DIHYDROPYRAZINE//FRUCTOSAZINE//BIOCHEM ISOTOPE
10 17114 DUOCARMYCIN//CC 1065//ADOZELESIN

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