Class information for:
Level 1: RMP 7//INTRACAROTID CHEMOTHERAPY//BLOOD TUMOR BARRIER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12145 928 32.5 60%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
258 3       STROKE//INTRACEREBRAL HEMORRHAGE//CEREBRAL ISCHEMIA 44849
2409 2             BLOOD BRAIN BARRIER//CEREBROLYSIN//TYR MIF 1 4189
12145 1                   RMP 7//INTRACAROTID CHEMOTHERAPY//BLOOD TUMOR BARRIER 928

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RMP 7 authKW 323956 2% 62% 16
2 INTRACAROTID CHEMOTHERAPY authKW 201529 1% 88% 7
3 BLOOD TUMOR BARRIER authKW 193519 2% 29% 20
4 BLOOD BRAIN BARRIER DISRUPTION authKW 171203 2% 24% 22
5 RG2 GLIOMA authKW 161220 1% 70% 7
6 INTRA ARTERIAL authKW 143673 3% 14% 31
7 INTRACAROTID INFUSION authKW 118446 1% 60% 6
8 INTRACAROTID ADMINISTRATION authKW 98709 0% 100% 3
9 LOBRADIMIL authKW 98709 0% 100% 3
10 OSMOTIC BBB DISRUPTION authKW 98709 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Clinical Neurology 8059 41% 0% 378
2 Oncology 3636 33% 0% 308
3 Surgery 804 17% 0% 162
4 Neuroimaging 752 4% 0% 34
5 Neurosciences 614 17% 0% 158
6 Radiology, Nuclear Medicine & Medical Imaging 432 9% 0% 88
7 Pharmacology & Pharmacy 143 10% 0% 91
8 Anesthesiology 119 2% 0% 23
9 Ophthalmology 93 3% 0% 31
10 Pathology 40 3% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROL L603 65806 0% 100% 2
2 WEILL CORNELL BRAIN TUMOR 43286 1% 26% 5
3 BIOMED ENGN ELECT ENGN PHYS 32903 0% 100% 1
4 BIOMED ENGN ELECT ENGN PHYS MED 32903 0% 100% 1
5 CHEM THER EUT ANALYT PHARMACOL CORE 32903 0% 100% 1
6 CITIGRP BIOMED IMAGING CORE IL CBIC 32903 0% 100% 1
7 CITIGRP BIOMED IMAGING CORE IL CIBC 32903 0% 100% 1
8 CNRSUMR 7225ICM 32903 0% 100% 1
9 DIAGNOSZT ONKORADIOL INT 32903 0% 100% 1
10 FUNCT NEUROL SURG 32903 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEURO-ONCOLOGY 62270 11% 2% 101
2 CANCER DRUG DELIVERY 10200 1% 5% 6
3 JOURNAL OF NEUROSURGERY 8776 6% 0% 60
4 SELECTIVE CANCER THERAPEUTICS 8623 0% 7% 4
5 CANCER TREATMENT REPORTS 7866 2% 1% 23
6 PROGRESS IN EXPERIMENTAL TUMOR RESEARCH 7627 1% 3% 7
7 NEUROSURGERY 6276 5% 0% 50
8 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 2439 2% 0% 20
9 AMERICAN JOURNAL OF NEURORADIOLOGY 1459 2% 0% 22
10 NEUROLOGICAL RESEARCH 1188 1% 0% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RMP 7 323956 2% 62% 16 Search RMP+7 Search RMP+7
2 INTRACAROTID CHEMOTHERAPY 201529 1% 88% 7 Search INTRACAROTID+CHEMOTHERAPY Search INTRACAROTID+CHEMOTHERAPY
3 BLOOD TUMOR BARRIER 193519 2% 29% 20 Search BLOOD+TUMOR+BARRIER Search BLOOD+TUMOR+BARRIER
4 BLOOD BRAIN BARRIER DISRUPTION 171203 2% 24% 22 Search BLOOD+BRAIN+BARRIER+DISRUPTION Search BLOOD+BRAIN+BARRIER+DISRUPTION
5 RG2 GLIOMA 161220 1% 70% 7 Search RG2+GLIOMA Search RG2+GLIOMA
6 INTRA ARTERIAL 143673 3% 14% 31 Search INTRA+ARTERIAL Search INTRA+ARTERIAL
7 INTRACAROTID INFUSION 118446 1% 60% 6 Search INTRACAROTID+INFUSION Search INTRACAROTID+INFUSION
8 INTRACAROTID ADMINISTRATION 98709 0% 100% 3 Search INTRACAROTID+ADMINISTRATION Search INTRACAROTID+ADMINISTRATION
9 LOBRADIMIL 98709 0% 100% 3 Search LOBRADIMIL Search LOBRADIMIL
10 OSMOTIC BBB DISRUPTION 98709 0% 100% 3 Search OSMOTIC+BBB+DISRUPTION Search OSMOTIC+BBB+DISRUPTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SU, YS , ALI, R , FEROZE, AH , LI, G , LAWTON, MT , CHOUDHRI, O , (2016) ENDOVASCULAR THERAPIES FOR MALIGNANT GLIOMAS: CHALLENGES AND THE FUTURE.JOURNAL OF CLINICAL NEUROSCIENCE. VOL. 26. ISSUE . P. 26 -32 37 57% 2
2 JOSHI, S , MEYERS, PM , ORNSTEIN, E , (2008) INTRACAROTID DELIVERY OF DRUGS - THE POTENTIAL AND THE PITFALLS.ANESTHESIOLOGY. VOL. 109. ISSUE 3. P. 543 -564 61 39% 11
3 JOSHI, S , SINGH-MOON, R , WANG, M , BRUCE, JN , BIGIO, IJ , MAYEVSKY, A , (2014) REAL-TIME HEMODYNAMIC RESPONSE AND MITOCHONDRIAL FUNCTION CHANGES WITH INTRACAROTID MANNITOL INJECTION.BRAIN RESEARCH. VOL. 1549. ISSUE . P. 42-51 30 68% 1
4 SHAPIRO, WR , GREEN, SB , BURGER, PC , SELKER, RG , VANGILDER, JC , ROBERTSON, JT , MEALEY, J , RANSOHOFF, J , MAHALEY, MS , (1992) A RANDOMIZED COMPARISON OF INTRAARTERIAL VERSUS INTRAVENOUS BCNU, WITH OR WITHOUT INTRAVENOUS 5-FLUOROURACIL, FOR NEWLY DIAGNOSED PATIENTS WITH MALIGNANT GLIOMA.JOURNAL OF NEUROSURGERY. VOL. 76. ISSUE 5. P. 772-781 38 84% 160
5 WANG, M , ETU, J , JOSHI, S , (2007) ENHANCED DISRUPTION OF THE BLOOD BRAIN BARRIER BY INTRACAROTID MANNITOL INJECTION DURING TRANSIENT CEREBRAL HYPOPERFUSION IN RABBITS.JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY. VOL. 19. ISSUE 4. P. 249-256 28 78% 21
6 BURKHARDT, JK , RIINA, HA , SHIN, BJ , MOLITERNO, JA , HOFSTETTER, CP , BOOCKVAR, JA , (2011) INTRA-ARTERIAL CHEMOTHERAPY FOR MALIGNANT GLIOMAS: A CRITICAL ANALYSIS.INTERVENTIONAL NEURORADIOLOGY. VOL. 17. ISSUE 3. P. 286-295 34 57% 13
7 RAPOPORT, SI , (2001) ADVANCES IN OSMOTIC OPENING OF THE BLOOD-BRAIN BARRIER TO ENHANCE CNS CHEMOTHERAPY.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 10. ISSUE 10. P. 1809-1818 39 62% 55
8 ELLIOTT, PJ , HAYWARD, NJ , DEAN, RL , BLUNT, DG , BARTUS, RT , (1996) INTRAVENOUS RMP-7 SELECTIVELY INCREASES UPTAKE OF CARBOPLATIN INTO RAT BRAIN TUMORS.CANCER RESEARCH. VOL. 56. ISSUE 17. P. 3998-4005 33 72% 46
9 BLANCHETTE, M , TREMBLAY, L , LEPAGE, M , FORTIN, D , (2014) IMPACT OF DRUG SIZE ON BRAIN TUMOR AND BRAIN PARENCHYMA DELIVERY AFTER A BLOOD-BRAIN BARRIER DISRUPTION.JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. VOL. 34. ISSUE 5. P. 820-826 23 62% 5
10 DOOLITTLE, ND , MINER, ME , HALL, WA , SIEGAL, T , HANSON, EJ , OSZTIE, E , MCALLISTER, LD , BUBALO, JS , KRAEMER, DF , FORTIN, D , ET AL (2000) SAFETY AND EFFICACY OF A MULTICENTER STUDY USING INTRAARTERIAL CHEMOTHERAPY IN CONJUNCTION WITH OSMOTIC OPENING OF THE BLOOD-BRAIN BARRIER FOR THE TREATMENT OF PATIENTS WITH MALIGNANT BRAIN TUMORS.CANCER. VOL. 88. ISSUE 3. P. 637-647 25 68% 190

Classes with closest relation at Level 1


Rank Class id link
1 27403 EVANS BLUE//1 DEOXY 1 NITRO D MANNITOL//ADENYLATE CYSLASE
2 14667 CONVECTION ENHANCED DELIVERY//FUNCT NEUROSURG GRP//INTRATUMORAL DRUG DELIVERY
3 23064 FOCUSED ULTRASOUND//BLOOD BRAIN BARRIER OPENING//BLOOD BRAIN BARRIER DISRUPTION
4 1424 TEMOZOLOMIDE//GLIOBLASTOMA//GLIOBLASTOMA MULTIFORME
5 27774 VASOGENIC BRAIN EDEMA//IMMUNOGLOBULIN G UPTAKE//NECROTIC NEURONS
6 6821 BLOOD BRAIN BARRIER//BRAIN TARGETING//SMART DRUG DELIVERY
7 4989 BLOOD BRAIN BARRIER//BBB//TIGHT JUNCTION
8 23773 BIETTI CRYSTALLINE DYSTROPHY//CRYSTALLINE RETINOPATHY//CYP4V2
9 18162 HUMAN MALIGNANT GLIOMAS//MOL EXPT RADIOL//GLIOMA
10 16078 S 2250 KAWAGISHI//TAUROMUSTINE//SARCNU

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