Class information for:
Level 1: FOCUSED ULTRASOUND//BLOOD BRAIN BARRIER OPENING//BLOOD BRAIN BARRIER DISRUPTION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23064 359 40.6 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
16 4 ENGINEERING, CIVIL//CONSTRUCTION & BUILDING TECHNOLOGY//MECHANICS 627508
288 3       ACOUSTICS//ULTRASONICS//ULTRASOUND IN MEDICINE AND BIOLOGY 42267
1224 2             MICROBUBBLES//ULTRASOUND IN MEDICINE AND BIOLOGY//HIGH INTENSITY FOCUSED ULTRASOUND 9117
23064 1                   FOCUSED ULTRASOUND//BLOOD BRAIN BARRIER OPENING//BLOOD BRAIN BARRIER DISRUPTION 359

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FOCUSED ULTRASOUND authKW 2758911 33% 28% 117
2 BLOOD BRAIN BARRIER OPENING authKW 235533 2% 46% 6
3 BLOOD BRAIN BARRIER DISRUPTION authKW 205756 4% 16% 15
4 DIAGNOST RADIOL INTERVENT address 193304 1% 45% 5
5 INTENSE FOCUSED ULTRASOUND authKW 151206 1% 44% 4
6 MED IMAGE RADIOL SCI address 141753 1% 33% 5
7 FOCUSED ULTRASOUND FUS authKW 136085 1% 40% 4
8 BLOOD BRAIN BARRIER authKW 132484 31% 1% 112
9 CARTHERA TEAM address 113407 1% 67% 2
10 UNFOCUSED ULTRASOUND authKW 113407 1% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Acoustics 5709 24% 0% 86
2 Radiology, Nuclear Medicine & Medical Imaging 2905 35% 0% 126
3 Neurosciences 617 26% 0% 92
4 Engineering, Biomedical 435 9% 0% 33
5 Pharmacology & Pharmacy 128 13% 0% 48
6 Clinical Neurology 105 9% 0% 32
7 Medicine, Research & Experimental 88 7% 0% 25
8 Multidisciplinary Sciences 81 3% 0% 10
9 Neuroimaging 54 2% 0% 6
10 Materials Science, Biomaterials 38 2% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIAGNOST RADIOL INTERVENT 193304 1% 45% 5
2 MED IMAGE RADIOL SCI 141753 1% 33% 5
3 CARTHERA TEAM 113407 1% 67% 2
4 BIOMED SHENZHEN PKU HKUST MED 85056 0% 100% 1
5 CAMIT 85056 0% 100% 1
6 CARTHERA 85056 0% 100% 1
7 CTO FUTURE IT 85056 0% 100% 1
8 EMERGING DEF TECHNOL 85056 0% 100% 1
9 FOCUSED ULTRASOUND RADIOLMED 85056 0% 100% 1
10 HLTH SCI ARIZONA CANC 85056 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ULTRASOUND IN MEDICINE AND BIOLOGY 32531 13% 1% 46
2 JOURNAL OF CONTROLLED RELEASE 5028 6% 0% 21
3 BRAIN STIMULATION 4484 2% 1% 6
4 INTERNATIONAL JOURNAL OF IMAGING SYSTEMS AND TECHNOLOGY 2492 1% 1% 5
5 THERANOSTICS 2314 1% 1% 4
6 PHYSICS IN MEDICINE AND BIOLOGY 1303 4% 0% 13
7 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 1280 3% 0% 9
8 IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL 1229 3% 0% 9
9 INTERNATIONAL JOURNAL OF NANOMEDICINE 655 1% 0% 5
10 JOURNAL OF MOLECULAR NEUROSCIENCE 494 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FOCUSED ULTRASOUND 2758911 33% 28% 117 Search FOCUSED+ULTRASOUND Search FOCUSED+ULTRASOUND
2 BLOOD BRAIN BARRIER OPENING 235533 2% 46% 6 Search BLOOD+BRAIN+BARRIER+OPENING Search BLOOD+BRAIN+BARRIER+OPENING
3 BLOOD BRAIN BARRIER DISRUPTION 205756 4% 16% 15 Search BLOOD+BRAIN+BARRIER+DISRUPTION Search BLOOD+BRAIN+BARRIER+DISRUPTION
4 INTENSE FOCUSED ULTRASOUND 151206 1% 44% 4 Search INTENSE+FOCUSED+ULTRASOUND Search INTENSE+FOCUSED+ULTRASOUND
5 FOCUSED ULTRASOUND FUS 136085 1% 40% 4 Search FOCUSED+ULTRASOUND+FUS Search FOCUSED+ULTRASOUND+FUS
6 BLOOD BRAIN BARRIER 132484 31% 1% 112 Search BLOOD+BRAIN+BARRIER Search BLOOD+BRAIN+BARRIER
7 UNFOCUSED ULTRASOUND 113407 1% 67% 2 Search UNFOCUSED+ULTRASOUND Search UNFOCUSED+ULTRASOUND
8 MICROBUBBLES 93810 12% 3% 42 Search MICROBUBBLES Search MICROBUBBLES
9 BBB OPENING TECHNIQUE 85056 0% 100% 1 Search BBB+OPENING+TECHNIQUE Search BBB+OPENING+TECHNIQUE
10 BRAIN MAGNETIC FIELD 85056 0% 100% 1 Search BRAIN+MAGNETIC+FIELD Search BRAIN+MAGNETIC+FIELD

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ARYAL, M , ARVANITIS, CD , ALEXANDER, PM , MCDANNOLD, N , (2014) ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER DISRUPTION FOR TARGETED DRUG DELIVERY IN THE CENTRAL NERVOUS SYSTEM.ADVANCED DRUG DELIVERY REVIEWS. VOL. 72. ISSUE . P. 94 -109 89 52% 49
2 BURGESS, A , HYNYNEN, K , (2016) MICROBUBBLE-ASSISTED ULTRASOUND FOR DRUG DELIVERY IN THE BRAIN AND CENTRAL NERVOUS SYSTEM.THERAPEUTIC ULTRASOUND. VOL. 880. ISSUE . P. 293 -308 65 68% 2
3 BURGESS, A , HYNYNEN, K , (2014) DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER USING FOCUSED ULTRASOUND.EXPERT OPINION ON DRUG DELIVERY. VOL. 11. ISSUE 5. P. 711-721 55 74% 14
4 O'REILLY, MA , HYNYNEN, K , (2012) ULTRASOUND ENHANCED DRUG DELIVERY TO THE BRAIN AND CENTRAL NERVOUS SYSTEM.INTERNATIONAL JOURNAL OF HYPERTHERMIA. VOL. 28. ISSUE 4. P. 386-396 57 69% 18
5 BURGESS, A , SHAH, K , HOUGH, O , HYNYNEN, K , (2015) FOCUSED ULTRASOUND-MEDIATED DRUG DELIVERY THROUGH THE BLOOD-BRAIN BARRIER.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 15. ISSUE 5. P. 477 -491 53 55% 9
6 BURGESS, A , HYNYNEN, K , (2013) NONINVASIVE AND TARGETED DRUG DELIVERY TO THE BRAIN USING FOCUSED ULTRASOUND.ACS CHEMICAL NEUROSCIENCE. VOL. 4. ISSUE 4. P. 519-526 47 64% 19
7 CHU, PC , CHAI, WY , TSAI, CH , KANG, ST , YEH, CK , LIU, HL , (2016) FOCUSED ULTRASOUND-INDUCED BLOOD-BRAIN BARRIER OPENING: ASSOCIATION WITH MECHANICAL INDEX AND CAVITATION INDEX ANALYZED BY DYNAMIC CONTRAST-ENHANCED MAGNETIC-RESONANCE IMAGING.SCIENTIFIC REPORTS. VOL. 6. ISSUE . P. - 36 80% 0
8 LEINENGA, G , LANGTON, C , NISBET, R , GOTZ, J , (2016) ULTRASOUND TREATMENT OF NEUROLOGICAL DISEASES - CURRENT AND EMERGING APPLICATIONS.NATURE REVIEWS NEUROLOGY. VOL. 12. ISSUE 3. P. 161 -174 48 46% 4
9 SUN, T , SAMIOTAKI, G , WANG, S , ACOSTA, C , CHEN, CC , KONOFAGOU, EE , (2015) ACOUSTIC CAVITATION-BASED MONITORING OF THE REVERSIBILITY AND PERMEABILITY OF ULTRASOUND-INDUCED BLOOD-BRAIN BARRIER OPENING.PHYSICS IN MEDICINE AND BIOLOGY. VOL. 60. ISSUE 23. P. 9079 -9094 30 81% 5
10 LIU, HL , FAN, CH , TING, CY , YEH, CK , (2014) COMBINING MICROBUBBLES AND ULTRASOUND FOR DRUG DELIVERY TO BRAIN TUMORS: CURRENT PROGRESS AND OVERVIEW.THERANOSTICS. VOL. 4. ISSUE 4. P. 432-444 44 45% 39

Classes with closest relation at Level 1


Rank Class id link
1 1641 HIGH INTENSITY FOCUSED ULTRASOUND//HIFU//FOCUSED ULTRASOUND
2 850 MICROBUBBLES//SONOPORATION//ULTRASOUND CONTRAST AGENT
3 12145 RMP 7//INTRACAROTID CHEMOTHERAPY//BLOOD TUMOR BARRIER
4 6821 BLOOD BRAIN BARRIER//BRAIN TARGETING//SMART DRUG DELIVERY
5 17927 SONOTHROMBOLYSIS//THROMBOLYSIS//ULTRASOUND ENHANCED THROMBOLYSIS
6 14667 CONVECTION ENHANCED DELIVERY//FUNCT NEUROSURG GRP//INTRATUMORAL DRUG DELIVERY
7 10308 BIOEFFECTS//ULTRASOUND SAFETY//ULTRASOUND IN MEDICINE AND BIOLOGY
8 37114 DIAGNOST NANOPARTICLES CORE//ALTERNATIVE MAGNETIC FIELDS//BEVERLY RAYMOND SADDER EXACT SCI
9 19575 SONODYNAMIC THERAPY//SONOSENSITIZER//MED OURCES NAT PHARMACEUT CHEM
10 4989 BLOOD BRAIN BARRIER//BBB//TIGHT JUNCTION

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