Class information for:
Level 1: PODOPHYLLOTOXIN//DEOXYPODOPHYLLOTOXIN//PODOPHYLLUM HEXANDRUM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8392 1257 28.1 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
2 3       INTEGRATIVE & COMPLEMENTARY MEDICINE//CHEMISTRY, MEDICINAL//ESSENTIAL OIL 193989
1950 2             PODOPHYLLOTOXIN//LIGNANS//SCHISANDRA CHINENSIS 5724
8392 1                   PODOPHYLLOTOXIN//DEOXYPODOPHYLLOTOXIN//PODOPHYLLUM HEXANDRUM 1257

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PODOPHYLLOTOXIN authKW 4647697 22% 69% 277
2 DEOXYPODOPHYLLOTOXIN authKW 1031875 4% 90% 47
3 PODOPHYLLUM HEXANDRUM authKW 528350 3% 51% 43
4 PHARMACEUT DESIGN SYNTH address 425421 3% 52% 34
5 ANTHRISCUS SYLVESTRIS authKW 327914 1% 75% 18
6 PODOPHYLLOTOXIN DERIVATIVES authKW 324763 2% 70% 19
7 LINUM ALBUM authKW 287646 1% 79% 15
8 LIGNAN BIOSYNTHESIS authKW 269064 1% 92% 12
9 6 METHOXYPODOPHYLLOTOXIN authKW 249843 1% 86% 12
10 SINOPODOPHYLLUM EMODI authKW 244929 1% 92% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 12333 30% 0% 371
2 Chemistry, Organic 2441 21% 0% 263
3 Plant Sciences 1984 19% 0% 233
4 Pharmacology & Pharmacy 1685 23% 0% 290
5 Integrative & Complementary Medicine 835 3% 0% 41
6 Chemistry, Multidisciplinary 408 14% 0% 180
7 Biochemistry & Molecular Biology 328 18% 0% 220
8 Materials Science, Paper & Wood 195 2% 0% 20
9 Chemistry, Applied 118 4% 0% 46
10 Biotechnology & Applied Microbiology 102 5% 0% 67

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT DESIGN SYNTH 425421 3% 52% 34
2 ENTWICKLUNGS MOL BIOL PFLANZEN 178446 2% 28% 26
3 31423 KAMIOSAKI SHINAGAWA KU 124921 0% 86% 6
4 ANALYT ENVIRONM ENGN 101209 0% 83% 5
5 PESTICIDAL DESIGN SYNTH 89423 1% 41% 9
6 STEM CELLS GENE DRUG GANSU PROV 79491 0% 55% 6
7 PHARMAZEUT BIOL PHYTOCHEM 42599 1% 18% 10
8 ENVIRONM PLANT PROECT 32386 0% 67% 2
9 TECH OPERAT DEV 32386 0% 67% 2
10 UNITE RECH BIOL PLANTES INNOVAT BIOPI EA 3900 32386 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 4509 5% 0% 69
2 JOURNAL OF WOOD SCIENCE 3090 1% 1% 14
3 PHYTOCHEMISTRY 2899 4% 0% 52
4 PLANTA MEDICA 2886 2% 0% 29
5 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2302 2% 0% 30
6 BIOORGANIC & MEDICINAL CHEMISTRY 1987 3% 0% 33
7 JOURNAL OF NATURAL PRODUCTS 1659 2% 0% 29
8 JOURNAL OF MEDICINAL CHEMISTRY 1412 3% 0% 36
9 PLANT BIOTECHNOLOGY 1276 0% 1% 6
10 CHEMICAL & PHARMACEUTICAL BULLETIN 910 2% 0% 26

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PODOPHYLLOTOXIN 4647697 22% 69% 277 Search PODOPHYLLOTOXIN Search PODOPHYLLOTOXIN
2 DEOXYPODOPHYLLOTOXIN 1031875 4% 90% 47 Search DEOXYPODOPHYLLOTOXIN Search DEOXYPODOPHYLLOTOXIN
3 PODOPHYLLUM HEXANDRUM 528350 3% 51% 43 Search PODOPHYLLUM+HEXANDRUM Search PODOPHYLLUM+HEXANDRUM
4 ANTHRISCUS SYLVESTRIS 327914 1% 75% 18 Search ANTHRISCUS+SYLVESTRIS Search ANTHRISCUS+SYLVESTRIS
5 PODOPHYLLOTOXIN DERIVATIVES 324763 2% 70% 19 Search PODOPHYLLOTOXIN+DERIVATIVES Search PODOPHYLLOTOXIN+DERIVATIVES
6 LINUM ALBUM 287646 1% 79% 15 Search LINUM+ALBUM Search LINUM+ALBUM
7 LIGNAN BIOSYNTHESIS 269064 1% 92% 12 Search LIGNAN+BIOSYNTHESIS Search LIGNAN+BIOSYNTHESIS
8 6 METHOXYPODOPHYLLOTOXIN 249843 1% 86% 12 Search 6+METHOXYPODOPHYLLOTOXIN Search 6+METHOXYPODOPHYLLOTOXIN
9 SINOPODOPHYLLUM EMODI 244929 1% 92% 11 Search SINOPODOPHYLLUM+EMODI Search SINOPODOPHYLLUM+EMODI
10 LINACEAE 233161 2% 40% 24 Search LINACEAE Search LINACEAE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIU, YQ , TIAN, J , QIAN, K , ZHAO, XB , MORRIS-NATSCHKE, SL , YANG, L , NAN, X , TIAN, X , LEE, KH , (2015) RECENT PROGRESS ON C-4-MODIFIED PODOPHYLLOTOXIN ANALOGS AS POTENT ANTITUMOR AGENTS.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 1. P. 1 -62 120 81% 18
2 GORDALIZA, M , GARCIA, PA , DEL CORRAL, JMM , CASTRO, MA , GOMEZ-ZURITA, MA , (2004) PODOPHYLLOTOXIN: DISTRIBUTION, SOURCES, APPLICATIONS AND NEW CYTOTOXIC DERIVATIVES.TOXICON. VOL. 44. ISSUE 4. P. 441-459 108 65% 225
3 XU, H , LV, M , TIAN, X , (2009) A REVIEW ON HEMISYNTHESIS, BIOSYNTHESIS, BIOLOGICAL ACTIVITIES, MODE OF ACTION, AND STRUCTURE-ACTIVITY RELATIONSHIP OF PODOPHYLLOTOXINS: 2003-2007.CURRENT MEDICINAL CHEMISTRY. VOL. 16. ISSUE 3. P. 327-349 75 78% 74
4 LAUTIE, E , FLINIAUX, MA , VILLARREAL, ML , (2010) UPDATED BIOTECHNOLOGICAL APPROACHES DEVELOPED FOR 2,7 '-CYCLOLIGNAN PRODUCTION.BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. VOL. 55. ISSUE . P. 139 -153 78 83% 1
5 MALIK, S , BIBA, O , GRUZ, J , ARROO, RRJ , STRNAD, M , (2014) BIOTECHNOLOGICAL APPROACHES FOR PRODUCING ARYLTETRALIN LIGNANS FROM LINUM SPECIES.PHYTOCHEMISTRY REVIEWS. VOL. 13. ISSUE 4. P. 893 -913 65 71% 8
6 GORDALIZA, M , CASTRO, MA , DEL CORRAL, JMM , SAN FELICIANO, A , (2000) ANTITUMOR PROPERTIES OF PODOPHYLLOTOXIN AND RELATED COMPOUNDS.CURRENT PHARMACEUTICAL DESIGN. VOL. 6. ISSUE 18. P. 1811 -1839 75 49% 137
7 FARKYA, S , BISARIA, VS , SRIVASTAVA, AK , (2004) BIOTECHNOLOGICAL ASPECTS OF THE PRODUCTION OF THE ANTICANCER DRUG PODOPHYLLOTOXIN.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 65. ISSUE 5. P. 504-519 58 64% 29
8 KAMAL, A , HUSSAINI, SMA , MALIK, MS , (2015) RECENT DEVELOPMENTS TOWARDS PODOPHYLLOTOXIN CONGENERS AS POTENTIAL APOPTOSIS INDUCERS.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 5. P. 565 -574 33 80% 3
9 OLARU, OT , NITULESCU, GM , ORTAN, A , DINU-PIRVU, CE , (2015) ETHNOMEDICINAL, PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF ANTHRISCUS SYLVESTRIS AS AN ALTERNATIVE SOURCE FOR ANTICANCER LIGNANS.MOLECULES. VOL. 20. ISSUE 8. P. 15003 -15022 48 56% 0
10 YOU, YJ , (2005) PODOPHYLLOTOXIN DERIVATIVES: CURRENT SYNTHETIC APPROACHES FOR NEW ANTICANCER AGENTS.CURRENT PHARMACEUTICAL DESIGN. VOL. 11. ISSUE 13. P. 1695-1717 68 43% 105

Classes with closest relation at Level 1


Rank Class id link
1 6611 LIGNANS//MAGNOLIA FARGESII//CUBEBIN
2 26223 CLEISTANTHUS COLLINUS//JUSTICIA PROCUMBENS//CLEISTANTHIN A
3 10766 ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE
4 2662 TOPOISOMERASE II//DNA TOPOISOMERASE II//TOPOISOMERASE II ALPHA
5 34573 CI 980//1 ACETYLINDOLINE//ALPHA AMINOALKYL ARYL KETONE
6 27661 FORSYTHIASIDE//PHILLYRIN//FORSYTHIA SUSPENSA
7 33351 POST STUDIES BIOTECHNOL//SAHYADRI SCI AUTONOMOUS//ITACONIC ACIDS
8 5476 COMBRETASTATIN//COMBRETASTATIN A 4//VASCULAR DISRUPTING AGENTS
9 25483 ARCTIGENIN//ARCTIIN//ARCTIUM LAPPA
10 33041 HYPTIS SUAVEOLENS//HYPTIDENDRON CANUM//HYPTIS CRENATA

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