Class information for:
Level 1: FCRN//NEONATAL FC RECEPTOR//TARGET MEDIATED DRUG DISPOSITION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10569 1052 45.2 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
350 3       COMPLEMENT//MANNOSE BINDING LECTIN//IMMUNOLOGY 35656
1655 2             BIOSIMILAR//FCRN//PROTEIN FORMULATION 6878
10569 1                   FCRN//NEONATAL FC RECEPTOR//TARGET MEDIATED DRUG DISPOSITION 1052

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FCRN authKW 2889670 12% 78% 127
2 NEONATAL FC RECEPTOR authKW 1394597 6% 78% 62
3 TARGET MEDIATED DRUG DISPOSITION authKW 625871 3% 74% 29
4 NEONATAL FC RECEPTOR FCRN authKW 520282 2% 81% 22
5 ROSENSTIEL BASIC BIOMED SCI address 232188 1% 67% 12
6 FCGRT authKW 206394 1% 89% 8
7 PHARMACOKINET PHARMACODYNAM SCI address 158242 2% 32% 17
8 IGG CATABOLISM authKW 158019 1% 78% 7
9 TMDD authKW 154792 1% 67% 8
10 ANTIBODY PHARMACOKINETICS authKW 149267 1% 86% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 3139 27% 0% 285
2 Pharmacology & Pharmacy 2687 31% 0% 323
3 Medicine, Research & Experimental 518 9% 0% 98
4 Reproductive Biology 407 4% 0% 44
5 Biochemistry & Molecular Biology 156 15% 0% 153
6 Cell Biology 91 7% 0% 72
7 Developmental Biology 60 2% 0% 20
8 Biochemical Research Methods 52 3% 0% 35
9 Chemistry, Medicinal 51 3% 0% 30
10 Chemistry, Multidisciplinary 35 7% 0% 74

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ROSENSTIEL BASIC BIOMED SCI 232188 1% 67% 12
2 PHARMACOKINET PHARMACODYNAM SCI 158242 2% 32% 17
3 DRUG DISPOSIT DEV COMMERCIALIZAT 74627 1% 43% 6
4 WM KECK CELLULAR VISUALIZAT 69091 1% 24% 10
5 DAVIS HEART LUNG 012K 65304 0% 75% 3
6 CLIN PHARMACOL ONCOL BUSINESS UNIT 58049 0% 100% 2
7 DAVIS HEART LUNG 425 58049 0% 100% 2
8 LARGE MOL BIOANALYT DEV 58049 0% 100% 2
9 ROSENTIEL BASIC BIOMED SCI 58049 0% 100% 2
10 TRANSLAT MODELING SIMULAT 58049 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MABS 128020 5% 8% 57
2 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 63905 3% 6% 36
3 AAPS JOURNAL 24623 3% 3% 31
4 PHARMACEUTICAL RESEARCH 4657 3% 0% 36
5 PROTEIN ENGINEERING DESIGN & SELECTION 2776 1% 1% 10
6 CLINICAL PHARMACOKINETICS 2062 1% 1% 13
7 JOURNAL OF CLINICAL PHARMACOLOGY 1899 2% 0% 19
8 JOURNAL OF REPRODUCTIVE IMMUNOLOGY 1751 1% 1% 11
9 PLACENTA 1642 1% 0% 15
10 DRUG METABOLISM AND PHARMACOKINETICS 1437 1% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FCRN 2889670 12% 78% 127 Search FCRN Search FCRN
2 NEONATAL FC RECEPTOR 1394597 6% 78% 62 Search NEONATAL+FC+RECEPTOR Search NEONATAL+FC+RECEPTOR
3 TARGET MEDIATED DRUG DISPOSITION 625871 3% 74% 29 Search TARGET+MEDIATED+DRUG+DISPOSITION Search TARGET+MEDIATED+DRUG+DISPOSITION
4 NEONATAL FC RECEPTOR FCRN 520282 2% 81% 22 Search NEONATAL+FC+RECEPTOR+FCRN Search NEONATAL+FC+RECEPTOR+FCRN
5 FCGRT 206394 1% 89% 8 Search FCGRT Search FCGRT
6 IGG CATABOLISM 158019 1% 78% 7 Search IGG+CATABOLISM Search IGG+CATABOLISM
7 TMDD 154792 1% 67% 8 Search TMDD Search TMDD
8 ANTIBODY PHARMACOKINETICS 149267 1% 86% 6 Search ANTIBODY+PHARMACOKINETICS Search ANTIBODY+PHARMACOKINETICS
9 IGG TRANSPORT 116094 1% 67% 6 Search IGG+TRANSPORT Search IGG+TRANSPORT
10 SERUM HALF LIFE 97946 1% 38% 9 Search SERUM+HALF+LIFE Search SERUM+HALF+LIFE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GIRAGOSSIAN, C , CLARK, T , PICHE-NICHOLAS, N , BOWMAN, CJ , (2013) NEONATAL FC RECEPTOR AND ITS ROLE IN THE ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION OF IMMUNOGLOBULIN G-BASED BIOTHERAPEUTICS.CURRENT DRUG METABOLISM. VOL. 14. ISSUE 7. P. 764-790 191 62% 14
2 SOCKOLOSKY, JT , SZOKA, FC , (2015) THE NEONATAL FC RECEPTOR, FCRN, AS A TARGET FOR DRUG DELIVERY AND THERAPY.ADVANCED DRUG DELIVERY REVIEWS. VOL. 91. ISSUE . P. 109 -124 125 79% 13
3 WARD, ES , DEVANABOYINA, SC , OBER, RJ , (2015) TARGETING FCRN FOR THE MODULATION OF ANTIBODY DYNAMICS.MOLECULAR IMMUNOLOGY. VOL. 67. ISSUE 2. P. 131 -141 112 80% 8
4 ROOPENIAN, DC , AKILESH, S , (2007) FCRN: THE NEONATAL FC RECEPTOR COMES OF AGE.NATURE REVIEWS IMMUNOLOGY. VOL. 7. ISSUE 9. P. 715 -725 72 84% 676
5 MARTINS, JP , KENNEDY, PJ , SANTOS, HA , BARRIAS, C , SARMENTO, B , (2016) A COMPREHENSIVE REVIEW OF THE NEONATAL FC RECEPTOR AND ITS APPLICATION IN DRUG DELIVERY.PHARMACOLOGY & THERAPEUTICS. VOL. 161. ISSUE . P. 22 -39 134 65% 1
6 KUO, TT , BAKER, K , YOSHIDA, M , QIAO, SW , AVESON, VG , LENCER, WI , BLUMBERG, RS , (2010) NEONATAL FC RECEPTOR: FROM IMMUNITY TO THERAPEUTICS.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 30. ISSUE 6. P. 777 -789 95 86% 88
7 RATH, T , KUO, TT , BAKER, K , QIAO, SW , KOBAYASHI, K , YOSHIDA, M , ROOPENIAN, D , FIEBIGER, E , LENCER, WI , BLUMBERG, RS , (2013) THE IMMUNOLOGIC FUNCTIONS OF THE NEONATAL FC RECEPTOR FOR IGG.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 33. ISSUE . P. S9-S17 74 90% 37
8 SAND, KMK , BERN, M , NILSEN, J , NOORDZIJ, HT , SANDLIE, I , ANDERSEN, JT , (2015) UNRAVELING THE INTERACTION BETWEEN FCRN AND ALBUMIN: OPPORTUNITIES FOR DESIGN OF ALBUMIN-BASED THERAPEUTICS.FRONTIERS IN IMMUNOLOGY. VOL. 5. ISSUE . P. 1 -21 124 55% 6
9 PYZIK, M , RATH, T , LENCER, WI , BAKER, K , BLUMBERG, RS , (2015) FCRN: THE ARCHITECT BEHIND THE IMMUNE AND NONIMMUNE FUNCTIONS OF IGG AND ALBUMIN.JOURNAL OF IMMUNOLOGY. VOL. 194. ISSUE 10. P. 4595 -4603 78 76% 13
10 WARD, ES , OBER, RJ , (2009) MULTITASKING BY EXPLOITATION OF INTRACELLULAR TRANSPORT FUNCTIONS: THE MANY FACES OF FCRN.ADVANCES IN IMMUNOLOGY, VOL 103. VOL. 103. ISSUE . P. 77-115 112 65% 54

Classes with closest relation at Level 1


Rank Class id link
1 18498 BIOANALYSIS//ANTI DRUG ANTIBODIES//LIGAND BINDING ASSAY
2 4824 AGALACTOSYL IGG//MABS//PROT ANALYT CHEM
3 19046 TGN1412//MICROMINIPIG//MINIPIG
4 3124 FC RECEPTOR//FC GAMMA RECEPTORS//FC GAMMA RECEPTOR
5 10654 INTERSPECIES SCALING//VOLUME OF DISTRIBUTION//STEADY STATE VOLUME OF DISTRIBUTION
6 11281 ANTIBODY DRUG CONJUGATE//GEMTUZUMAB OZOGAMICIN//MYLOTARG
7 5621 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM//NONLINEAR MIXED EFFECTS MODEL
8 30257 ASYMMETRIC ANTIBODIES//CARBOHYDRATE ASSOCIATED EPITOPE//CA215
9 35662 A33 ANTIGEN//ADHESION REGULATING MOLECULE 1//ADRM1
10 14481 NANOBODY//SINGLE DOMAIN ANTIBODY//VHH

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