Class information for:
Level 1: BIOANALYSIS//ANTI DRUG ANTIBODIES//LIGAND BINDING ASSAY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18498 549 24.3 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
350 3       COMPLEMENT//MANNOSE BINDING LECTIN//IMMUNOLOGY 35656
1655 2             BIOSIMILAR//FCRN//PROTEIN FORMULATION 6878
18498 1                   BIOANALYSIS//ANTI DRUG ANTIBODIES//LIGAND BINDING ASSAY 549

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOANALYSIS journal 1410867 34% 13% 188
2 ANTI DRUG ANTIBODIES authKW 693359 7% 32% 39
3 LIGAND BINDING ASSAY authKW 662212 6% 37% 32
4 GYROLAB authKW 355957 1% 80% 8
5 NAB ASSAY authKW 231743 1% 83% 5
6 SERUM BASED BIOASSAY authKW 222475 1% 100% 4
7 AAPS JOURNAL journal 207833 12% 6% 65
8 ANTI DRUG ANTIBODY ADA authKW 200223 1% 60% 6
9 ANTI THERAPEUTIC ANTIBODY authKW 198636 1% 71% 5
10 PRE EXISTING ANTIBODIES authKW 198636 1% 71% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemical Research Methods 14797 54% 0% 298
2 Chemistry, Analytical 8527 53% 0% 291
3 Pharmacology & Pharmacy 1641 33% 0% 181
4 Immunology 509 16% 0% 88
5 Medical Laboratory Technology 49 2% 0% 10
6 Biotechnology & Applied Microbiology 24 4% 0% 24
7 Toxicology 4 2% 0% 9
8 Medicine, Legal 3 0% 0% 2
9 Statistics & Probability 1 1% 0% 5
10 Medicine, Research & Experimental 0 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOSTAT MED SCI 148314 1% 67% 4
2 PRECLIN CLIN DEV SCI 148314 1% 67% 4
3 MARKER LOCALIZAT ASSAYS 125141 1% 75% 3
4 THER EUT BIOL ONCOL PROD 125141 1% 75% 3
5 ANALYT BIOANALYT SCI 111238 0% 100% 2
6 BIOANAL IMMUNOL 111238 0% 100% 2
7 BIOANALYT SCI BIOL ANALYT BIOANALYT DEV 111238 0% 100% 2
8 BIOL PHARMA EARLY DEV PRED PENZBERG 111238 0% 100% 2
9 DMPK BIOANALYT RD 111238 0% 100% 2
10 PHARMACOKINET DYNAM METAB PDM NBE 111238 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOANALYSIS 1410867 34% 13% 188
2 AAPS JOURNAL 207833 12% 6% 65
3 JOURNAL OF IMMUNOLOGICAL METHODS 22891 11% 1% 63
4 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 14817 10% 0% 54
5 BIOPHARM-THE TECHNOLOGY & BUSINESS OF BIOPHARMACEUTICALS 5000 1% 3% 3
6 JOURNAL OF IMMUNOLOGY RESEARCH 3342 1% 1% 7
7 BIOPHARM INTERNATIONAL 1694 1% 1% 4
8 JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY 1239 1% 1% 3
9 JOURNAL OF BIOPHARMACEUTICAL STATISTICS 966 1% 0% 4
10 DRUG DISCOVERY TODAY 805 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ANTI DRUG ANTIBODIES 693359 7% 32% 39 Search ANTI+DRUG+ANTIBODIES Search ANTI+DRUG+ANTIBODIES
2 LIGAND BINDING ASSAY 662212 6% 37% 32 Search LIGAND+BINDING+ASSAY Search LIGAND+BINDING+ASSAY
3 GYROLAB 355957 1% 80% 8 Search GYROLAB Search GYROLAB
4 NAB ASSAY 231743 1% 83% 5 Search NAB+ASSAY Search NAB+ASSAY
5 SERUM BASED BIOASSAY 222475 1% 100% 4 Search SERUM+BASED+BIOASSAY Search SERUM+BASED+BIOASSAY
6 ANTI DRUG ANTIBODY ADA 200223 1% 60% 6 Search ANTI+DRUG+ANTIBODY+ADA Search ANTI+DRUG+ANTIBODY+ADA
7 ANTI THERAPEUTIC ANTIBODY 198636 1% 71% 5 Search ANTI+THERAPEUTIC+ANTIBODY Search ANTI+THERAPEUTIC+ANTIBODY
8 PRE EXISTING ANTIBODIES 198636 1% 71% 5 Search PRE+EXISTING+ANTIBODIES Search PRE+EXISTING+ANTIBODIES
9 CUT POINT 177331 2% 25% 13 Search CUT+POINT Search CUT+POINT
10 CRITICAL REAGENTS 166856 1% 100% 3 Search CRITICAL+REAGENTS Search CRITICAL+REAGENTS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, J , NOWATZKE, W , MA, M , (2015) CURRENT INDUSTRIAL PRACTICES AND REGULATORY REQUIREMENTS TO ASSESS ANALYTE AND REAGENT STABILITY USING LIGAND-BINDING ASSAYS.BIOANALYSIS. VOL. 7. ISSUE 11. P. 1371 -1384 30 81% 1
2 SLOAN, JH , CONWAY, RG , POTTANAT, TG , TROUTT, JS , HIGGS, RE , KONRAD, RJ , QIAN, YW , (2016) AN INNOVATIVE AND HIGHLY DRUG-TOLERANT APPROACH FOR DETECTING NEUTRALIZING ANTIBODIES DIRECTED TO THERAPEUTIC ANTIBODIES.BIOANALYSIS. VOL. 8. ISSUE 20. P. 2157 -2168 26 84% 0
3 JANI, D , KADAVIL, J , KAMERUD, J , KRAMER, D , LITWIN, V , SANTOS, GML , SANTOS, L , NELSON, R , NI, Y , PEDRAS-VASCONCELOS, J , ET AL (2016) 2016 WHITE PAPER ON RECENT ISSUES IN BIOANALYSIS: FOCUS ON BIOMARKER ASSAY VALIDATION (BAV): (PART 3-LBA, BIOMARKERS AND IMMUNOGENICITY).BIOANALYSIS. VOL. 8. ISSUE 23. P. 2475 -2496 30 65% 1
4 KUBIAK, RJ , ZHANG, LJ , ZHANG, JC , ZHU, Y , LEE, N , WEICHOLD, FF , YANG, H , ABRAHAM, V , AKUFONGWE, PF , HEWITT, L , ET AL (2013) CORRELATION OF SCREENING AND CONFIRMATORY RESULTS IN TIERED IMMUNOGENICITY TESTING BY SOLUTION-PHASE BRIDGING ASSAYS.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 74. ISSUE . P. 235-245 20 100% 7
5 AMARAVADI, L , SONG, A , MYLER, H , THWAY, T , KIRSHNER, S , DEVANARAYAN, V , NI, YG , GAROFOLO, F , BIRNBOECK, H , RICHARDS, S , ET AL (2015) 2015 WHITE PAPER ON RECENT ISSUES IN BIOANALYSIS: FOCUS ON NEW TECHNOLOGIES AND BIOMARKERS (PART 3-LBA, BIOMARKERS AND IMMUNOGENICITY).BIOANALYSIS. VOL. 7. ISSUE 24. P. 3107 -3124 26 74% 1
6 JANI, D , MARSDEN, R , MIKULSKIS, A , GLEASON, C , KLEM, T , FIOROTTI, CK , MYLER, H , YANG, L , FISCELLA, M , (2015) RECOMMENDATIONS FOR THE DEVELOPMENT AND VALIDATION OF CONFIRMATORY ANTI-DRUG ANTIBODY ASSAYS.BIOANALYSIS. VOL. 7. ISSUE 13. P. 1619 -1631 19 95% 2
7 FINDLAY, JWA , KELLEY, MM , (2014) ISR: BACKGROUND, EVOLUTION AND IMPLEMENTATION, WITH SPECIFIC CONSIDERATION FOR LIGAND-BINDING ASSAYS.BIOANALYSIS. VOL. 6. ISSUE 3. P. 393 -402 21 88% 1
8 SU, C , ZHOU, L , HU, Z , WENG, WN , SUBRAMANI, J , TADKOD, V , HAMILTON, K , BAUTISTA, A , WU, Y , CHIRMULE, N , ET AL (2015) ENHANCING EFFICIENCY AND QUALITY OF STATISTICAL ESTIMATION OF IMMUNOGENICITY ASSAY CUT POINTS THROUGH STANDARDIZATION AND AUTOMATION.JOURNAL OF IMMUNOLOGICAL METHODS. VOL. 425. ISSUE . P. 88 -96 18 90% 0
9 PARTRIDGE, MA , PURUSHOTHAMA, S , ELANGO, C , LU, YM , (2016) EMERGING TECHNOLOGIES AND GENERIC ASSAYS FOR THE DETECTION OF ANTI-DRUG ANTIBODIES.JOURNAL OF IMMUNOLOGY RESEARCH. VOL. . ISSUE . P. - 26 60% 0
10 MENENDEZ, AT , (2012) STRATEGIC SELECTION AND DEVELOPMENT OF IMMUNOGENICITY BINDING METHODS.BIOANALYSIS. VOL. 4. ISSUE 12. P. 1491-1508 21 78% 3

Classes with closest relation at Level 1


Rank Class id link
1 18346 ACCURACY PROFILE//TOTAL ERROR//ROBUSTNESS TESTING
2 14993 BIOSIMILAR//ANTI ERYTHROPOIETIN ANTIBODIES//CT P13
3 8403 ION SUPPRESSION//MATRIX EFFECT//BIOANALYT METAB PHARMACOKINET
4 9567 TARGETED PROTEOMICS//SELECTED REACTION MONITORING//MULTIPLE REACTION MONITORING
5 23394 HETEROPHILIC ANTIBODIES//HETEROPHILE ANTIBODIES//HAMA
6 10569 FCRN//NEONATAL FC RECEPTOR//TARGET MEDIATED DRUG DISPOSITION
7 20989 LUMINEX//FLOWMETRIX TM//LIQUID ARRAY TECHNOLOGY
8 24270 INTERFERON ANTIBODIES//CYTOKINE AUTOANTIBODIES//AUTOANTIBODIES TO CYTOKINES
9 17845 DRIED BLOOD SPOTS//BIOANALYSIS//DRIED BLOOD SPOT DBS
10 19046 TGN1412//MICROMINIPIG//MINIPIG

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