Class information for:
Level 2: SIGMA RECEPTOR//NMDA RECEPTOR//PHENCYCLIDINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
488 15502 43.8 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
100 3       NEUROSCIENCES//METABOTROPIC GLUTAMATE RECEPTOR//HIPPOCAMPUS 73970
488 2             SIGMA RECEPTOR//NMDA RECEPTOR//PHENCYCLIDINE 15502
1378 1                   KAINATE RECEPTOR//CYCLOTHIAZIDE//AMPA RECEPTOR 2691
2042 1                   NMDA RECEPTOR//NR2B//NR2A 2376
3540 1                   SIGMA RECEPTOR//SIGMA1 RECEPTOR//SIGMA 1 RECEPTOR 1962
5639 1                   HOMOCYSTEATE//2 AMINO 4 PHOSPHONOBUTANOIC ACID//BETA P CHLOROPHENYLGLUTAMATE 1594
6033 1                   ARCAINE//POLYAMINES//SPERMINE 1540
6946 1                   PHENCYCLIDINE//METAPHIT//BTCP 1425
7778 1                   KETAMINE//EXPT THER EUT PATHOPHYSIOL BRANCH//INTEGRAT BIOMED BRAIN DIS 1328
9910 1                   GLYT1//GLYCINE TRANSPORTER//GLYCINE TRANSPORTER INHIBITORS 1108
16847 1                   MK 801//NMDA ANTAGONIST//POSTERIOR CINGULATE AND RETROSPLENIAL CORTICES 632
19745 1                   MEMANTINE//AMANTADINE//UNCOMPETITIVE ANTAGONIST 491
23200 1                   D CYCLOSERINE//MILACEMIDE//CYCLOSERINE 355

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 SIGMA RECEPTOR authKW 645859 3% 78% 423
2 NMDA RECEPTOR authKW 536437 8% 22% 1236
3 PHENCYCLIDINE authKW 316082 2% 43% 373
4 KETAMINE authKW 231595 4% 19% 609
5 D CYCLOSERINE authKW 219714 1% 62% 180
6 GLUTAMATE RECEPTORS authKW 207347 3% 20% 520
7 SIGMA1 RECEPTOR authKW 207186 1% 90% 117
8 SIGMA 1 RECEPTOR authKW 204720 1% 82% 127
9 KAINATE RECEPTOR authKW 201815 1% 54% 189
10 NMDA authKW 152698 3% 15% 534

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 121893 51% 1% 7969
2 Pharmacology & Pharmacy 37327 30% 1% 4635
3 Psychiatry 10322 10% 0% 1589
4 Chemistry, Medicinal 8438 8% 0% 1177
5 Behavioral Sciences 3859 4% 0% 620
6 Biochemistry & Molecular Biology 1774 13% 0% 2086
7 Clinical Neurology 965 5% 0% 783
8 Physiology 878 4% 0% 563
9 Substance Abuse 558 1% 0% 170
10 Chemistry, Organic 261 4% 0% 565

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMAZEUT MED CHEM 61744 1% 31% 100
2 CELLULAR MOL NEUROPHYSIOL 45378 0% 47% 49
3 EXPT THER EUT PATHOPHYSIOL BRANCH 32177 0% 32% 52
4 CELLULAR PATHOBIOL SECT 29726 0% 66% 23
5 BEHAV NEUROPHARMACOL GRP 29631 0% 94% 16
6 FORENS MENTAL HLTH 22969 0% 20% 59
7 CELLULAR PATHOBIOL UNIT 19240 0% 65% 15
8 PHYSIOL CELLULAIRE SYN SE 18199 0% 51% 18
9 UNIT RECEPTOR BIOCHEM PHARMACOL 16395 0% 83% 10
10 U336 16161 0% 34% 24

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROPHARMACOLOGY 45234 3% 5% 467
2 EUROPEAN JOURNAL OF PHARMACOLOGY 29925 4% 2% 663
3 BRAIN RESEARCH 22256 5% 2% 748
4 JOURNAL OF NEUROCHEMISTRY 20989 3% 2% 479
5 NEUROSCIENCE LETTERS 18234 4% 2% 548
6 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 13758 3% 2% 392
7 JOURNAL OF NEUROSCIENCE 12972 3% 1% 485
8 JOURNAL OF MEDICINAL CHEMISTRY 11185 2% 2% 358
9 PSYCHOPHARMACOLOGY 10259 2% 2% 256
10 JOURNAL OF PSYCHEDELIC DRUGS 9765 0% 38% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 SIGMA RECEPTOR 645859 3% 78% 423 Search SIGMA+RECEPTOR Search SIGMA+RECEPTOR
2 NMDA RECEPTOR 536437 8% 22% 1236 Search NMDA+RECEPTOR Search NMDA+RECEPTOR
3 PHENCYCLIDINE 316082 2% 43% 373 Search PHENCYCLIDINE Search PHENCYCLIDINE
4 KETAMINE 231595 4% 19% 609 Search KETAMINE Search KETAMINE
5 D CYCLOSERINE 219714 1% 62% 180 Search D+CYCLOSERINE Search D+CYCLOSERINE
6 GLUTAMATE RECEPTORS 207347 3% 20% 520 Search GLUTAMATE+RECEPTORS Search GLUTAMATE+RECEPTORS
7 SIGMA1 RECEPTOR 207186 1% 90% 117 Search SIGMA1+RECEPTOR Search SIGMA1+RECEPTOR
8 SIGMA 1 RECEPTOR 204720 1% 82% 127 Search SIGMA+1+RECEPTOR Search SIGMA+1+RECEPTOR
9 KAINATE RECEPTOR 201815 1% 54% 189 Search KAINATE+RECEPTOR Search KAINATE+RECEPTOR
10 NMDA 152698 3% 15% 534 Search NMDA Search NMDA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TRAYNELIS, SF , WOLLMUTH, LP , MCBAIN, CJ , MENNITI, FS , VANCE, KM , OGDEN, KK , HANSEN, KB , YUAN, HJ , MYERS, SJ , DINGLEDINE, R , (2010) GLUTAMATE RECEPTOR ION CHANNELS: STRUCTURE, REGULATION, AND FUNCTION.PHARMACOLOGICAL REVIEWS. VOL. 62. ISSUE 3. P. 405 -496 770 59% 934
2 DINGLEDINE, R , BORGES, K , BOWIE, D , TRAYNELIS, SF , (1999) THE GLUTAMATE RECEPTOR ION CHANNELS.PHARMACOLOGICAL REVIEWS. VOL. 51. ISSUE 1. P. 7 -61 356 58% 2659
3 DANYSZ, W , PARSONS, CG , (1998) GLYCINE AND N-METHYL-D-ASPARTATE RECEPTORS: PHYSIOLOGICAL SIGNIFICANCE AND POSSIBLE THERAPEUTIC APPLICATIONS.PHARMACOLOGICAL REVIEWS. VOL. 50. ISSUE 4. P. 597 -664 464 62% 465
4 ROUSSEAUX, CG , GREENE, SF , (2016) SIGMA RECEPTORS [SIGMA RS]: BIOLOGY IN NORMAL AND DISEASED STATES.JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION. VOL. 36. ISSUE 4. P. 327 -388 476 49% 1
5 LEHMKUHL, K , JIA, H , WUNSCH, B , BRUST, P , DEUTHER-CONRAD, W , (2014) MOLECULAR IMAGING OF ALPHA(1) RECEPTORS IN VIVO: CURRENT STATUS AND PERSPECTIVES.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 1. P. 35 -69 228 84% 14
6 PAOLETTI, P , BELLONE, C , ZHOU, Q , (2013) NMDA RECEPTOR SUBUNIT DIVERSITY: IMPACT ON RECEPTOR PROPERTIES, SYNAPTIC PLASTICITY AND DISEASE.NATURE REVIEWS NEUROSCIENCE. VOL. 14. ISSUE 6. P. 383-400 132 68% 363
7 BANISTER, SD , KASSIOU, M , (2012) THE THERAPEUTIC POTENTIAL OF SIGMA (SIGMA) RECEPTORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES: EVALUATION OF THE EVIDENCE.CURRENT PHARMACEUTICAL DESIGN. VOL. 18. ISSUE 7. P. 884 -901 215 89% 19
8 MAURICE, T , SU, TP , (2009) THE PHARMACOLOGY OF SIGMA-1 RECEPTORS.PHARMACOLOGY & THERAPEUTICS. VOL. 124. ISSUE 2. P. 195 -206 146 90% 289
9 COBOS, EJ , ENTRENA, JM , NIETO, FR , CENDAN, CM , DEL POZO, E , (2008) PHARMACOLOGY AND THERAPEUTIC POTENTIAL OF SIGMA(1) RECEPTOR LIGANDS.CURRENT NEUROPHARMACOLOGY. VOL. 6. ISSUE 4. P. 344 -366 177 84% 163
10 JANE, DE , LODGE, D , COLLINGRIDGE, GL , (2009) KAINATE RECEPTORS: PHARMACOLOGY, FUNCTION AND THERAPEUTIC POTENTIAL.NEUROPHARMACOLOGY. VOL. 56. ISSUE 1. P. 90-113 170 88% 120

Classes with closest relation at Level 2


Rank Class id link
1 2259 METABOTROPIC GLUTAMATE RECEPTOR//MGLUR5//MPEP
2 891 POSTSYNAPTIC DENSITY//LONG TERM POTENTIATION//SYNAPTIC PLASTICITY
3 3624 DEXTROMETHORPHAN//LEVODROPROPIZINE//COUGH AND COLD MEDICATIONS
4 1829 GLYCINE RECEPTOR//HYPEREKPLEXIA//CYS LOOP RECEPTOR
5 984 KINDLING//EPILEPSY RESEARCH//KCC2
6 2761 CANAVAN DISEASE//N ACETYLASPARTYLGLUTAMATE//N ACETYLASPARTATE
7 2755 DOPAMINE TRANSPORTER//MONOAMINE TRANSPORTER//PSYCHOBIOL SECT
8 359 CEREBRAL ISCHEMIA//SPREADING DEPRESSION//JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
9 3423 RNA EDITING//ADAR//AEG 1
10 1054 GLUTAMATE TRANSPORTER//ASTROCYTES//GLIA

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