Class information for:
Level 1: ARCAINE//POLYAMINES//SPERMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6033 1540 38.1 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
100 3       NEUROSCIENCES//METABOTROPIC GLUTAMATE RECEPTOR//HIPPOCAMPUS 73970
488 2             SIGMA RECEPTOR//NMDA RECEPTOR//PHENCYCLIDINE 15502
6033 1                   ARCAINE//POLYAMINES//SPERMINE 1540

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARCAINE authKW 266539 1% 61% 22
2 POLYAMINES authKW 219426 15% 5% 226
3 SPERMINE authKW 182358 7% 9% 102
4 GLYCINE ANTAGONIST authKW 175005 1% 55% 16
5 SPERMIDINE authKW 166643 6% 9% 92
6 1 AMINOCYCLOPROPANECARBOXYLIC ACID authKW 152293 1% 59% 13
7 GLYCINE SITE authKW 149800 1% 33% 23
8 7 CHLOROKYNURENIC ACID authKW 146900 1% 44% 17
9 IFENPRODIL authKW 128416 2% 18% 36
10 NMDA RECEPTOR authKW 109642 11% 3% 176

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 11010 49% 0% 757
2 Pharmacology & Pharmacy 5163 35% 0% 535
3 Chemistry, Medicinal 1609 10% 0% 157
4 Biochemistry & Molecular Biology 212 14% 0% 219
5 Behavioral Sciences 92 2% 0% 34
6 Developmental Biology 86 2% 0% 29
7 Chemistry, Organic 77 5% 0% 76
8 Clinical Neurology 66 4% 0% 69
9 Psychiatry 12 2% 0% 34
10 Biochemical Research Methods 6 2% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 1 WAKEFIELD ST 19826 0% 100% 1
2 A STAR NUS 19826 0% 100% 1
3 ANIM EXPT PLATFORM 19826 0% 100% 1
4 AUSTIN HOSP CLIN PHARMACOL THER EUT UNIT 19826 0% 100% 1
5 BEHAV ELE OPHYSIOL SECT 19826 0% 100% 1
6 BRAIN IMAGING NEUROL DISABIL 19826 0% 100% 1
7 BRAIN IMAGING NEUROL DISABIL UMR 825 19826 0% 100% 1
8 CARDIFF S FO T FARM 19826 0% 100% 1
9 CHIM PHARMACEUT 2 19826 0% 100% 1
10 CI N SLDM TEP 19826 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION 23967 2% 3% 36
2 EUROPEAN JOURNAL OF PHARMACOLOGY 10233 8% 0% 121
3 JOURNAL OF NEUROCHEMISTRY 10005 7% 0% 103
4 BRAIN RESEARCH 6634 8% 0% 127
5 NEUROSCIENCE LETTERS 6533 7% 0% 102
6 NEUROPHARMACOLOGY 3001 2% 0% 38
7 NEUROCHEMISTRY INTERNATIONAL 2673 2% 1% 27
8 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2471 3% 0% 52
9 NEUROCHEMICAL PATHOLOGY 2432 0% 3% 4
10 MOLECULAR PHARMACOLOGY 2162 2% 0% 33

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ARCAINE 266539 1% 61% 22 Search ARCAINE Search ARCAINE
2 POLYAMINES 219426 15% 5% 226 Search POLYAMINES Search POLYAMINES
3 SPERMINE 182358 7% 9% 102 Search SPERMINE Search SPERMINE
4 GLYCINE ANTAGONIST 175005 1% 55% 16 Search GLYCINE+ANTAGONIST Search GLYCINE+ANTAGONIST
5 SPERMIDINE 166643 6% 9% 92 Search SPERMIDINE Search SPERMIDINE
6 1 AMINOCYCLOPROPANECARBOXYLIC ACID 152293 1% 59% 13 Search 1+AMINOCYCLOPROPANECARBOXYLIC+ACID Search 1+AMINOCYCLOPROPANECARBOXYLIC+ACID
7 GLYCINE SITE 149800 1% 33% 23 Search GLYCINE+SITE Search GLYCINE+SITE
8 7 CHLOROKYNURENIC ACID 146900 1% 44% 17 Search 7+CHLOROKYNURENIC+ACID Search 7+CHLOROKYNURENIC+ACID
9 IFENPRODIL 128416 2% 18% 36 Search IFENPRODIL Search IFENPRODIL
10 NMDA RECEPTOR 109642 11% 3% 176 Search NMDA+RECEPTOR Search NMDA+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DANYSZ, W , PARSONS, CG , (1998) GLYCINE AND N-METHYL-D-ASPARTATE RECEPTORS: PHYSIOLOGICAL SIGNIFICANCE AND POSSIBLE THERAPEUTIC APPLICATIONS.PHARMACOLOGICAL REVIEWS. VOL. 50. ISSUE 4. P. 597 -664 260 34% 465
2 LEESON, PD , IVERSEN, LL , (1994) THE GLYCINE SITE ON THE NMDA RECEPTOR - STRUCTURE-ACTIVITY-RELATIONSHIPS AND THERAPEUTIC POTENTIAL.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 37. ISSUE 24. P. 4053-4067 91 67% 271
3 LI, J , DOYLE, KM , TATLISUMAK, T , (2007) POLYAMINES IN THE BRAIN: DISTRIBUTION, BIOLOGICAL INTERACTIONS, AND THEIR POTENTIAL THERAPEUTIC ROLE IN BRAIN ISCHAEMIA.CURRENT MEDICINAL CHEMISTRY. VOL. 14. ISSUE 17. P. 1807-1813 58 60% 22
4 SOBRIO, F , GILBERT, G , PERRIO, C , BARRE, L , DEBRUYNE, D , (2010) PET AND SPECT IMAGING OF THE NMDA RECEPTOR SYSTEM: AN OVERVIEW OF RADIOTRACER DEVELOPMENT.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 9. P. 870-886 58 48% 30
5 KEMP, JA , LEESON, PD , (1993) THE GLYCINE SITE OF THE NMDA RECEPTOR - 5 YEARS ON.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 14. ISSUE 1. P. 20-25 47 72% 405
6 PASCHEN, W , CLEEF, M , ROHN, G , MULLER, M , PAJUNEN, AEI , (1993) ISCHEMIA-INDUCED DISTURBANCES OF POLYAMINE SYNTHESIS.PROGRESS IN BRAIN RESEARCH. VOL. 96. ISSUE . P. 147-160 64 71% 15
7 DEVERA, N , CAMON, L , MARTINEZ, E , (1997) POLYAMINES AND BRAIN INJURY.AMINO ACIDS. VOL. 12. ISSUE 1. P. 1-7 40 95% 7
8 PASCHEN, W , (1992) POLYAMINE METABOLISM IN DIFFERENT PATHOLOGICAL STATES OF THE BRAIN.MOLECULAR AND CHEMICAL NEUROPATHOLOGY. VOL. 16. ISSUE 3. P. 241-271 66 62% 79
9 NAGATA, R , KATAYAMA, S , OHTANI, KI , TANAKA, H , SHIMAGO, K , (2006) TRICYCLIC QUINOXALINEDIONES, AZA-KYNURENIC ACIDS, AND INDOLE-2-CARBOXYLIC ACIDS AS IN VIVO ACTIVE NMDA-GLYCINE ANTAGONISTS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 6. ISSUE 7. P. 733-745 42 64% 2
10 ROCK, DM , MACDONALD, RL , (1995) POLYAMINE REGULATION OF N-METHYL-D-ASPARTATE RECEPTOR CHANNELS.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 35. ISSUE . P. 463 -482 60 53% 126

Classes with closest relation at Level 1


Rank Class id link
1 2042 NMDA RECEPTOR//NR2B//NR2A
2 16847 MK 801//NMDA ANTAGONIST//POSTERIOR CINGULATE AND RETROSPLENIAL CORTICES
3 23200 D CYCLOSERINE//MILACEMIDE//CYCLOSERINE
4 5639 HOMOCYSTEATE//2 AMINO 4 PHOSPHONOBUTANOIC ACID//BETA P CHLOROPHENYLGLUTAMATE
5 6946 PHENCYCLIDINE//METAPHIT//BTCP
6 34927 REMACEMIDE//LOSIGAMONE//DESGLYCINYL REMACEMIDE
7 13747 MK 801//CGP 43487//JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION
8 22329 REGISTRAT SERV//NITROPHENOLIC HERBICIDE//3 METHOXY 4 HYDROXY PHENYL ETHYLENE GLYCOL
9 9910 GLYT1//GLYCINE TRANSPORTER//GLYCINE TRANSPORTER INHIBITORS
10 1378 KAINATE RECEPTOR//CYCLOTHIAZIDE//AMPA RECEPTOR

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