Class information for:
Level 2: BLEOMYCIN//MIGRASTATIN//BLEOMYCIN HYDROLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3321 1808 32.7 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
3321 2             BLEOMYCIN//MIGRASTATIN//BLEOMYCIN HYDROLASE 1808
9240 1                   BLEOMYCIN//BLEOMYCIN HYDROLASE//BLEOMYCIN RESISTANCE 1174
27406 1                   MIGRASTATIN//CYCLOHEXYLAMINOGLUTETHIMIDE//GLUTARIMIDE 230
27711 1                   PHENYLACETATE//ANTINEOPLASTON AS2 1//PHENYLBUTYRATE 223
29693 1                   BLEOMYCIN AMPLIFICATION//DNA DOCKING//2 5 DIARYLPYRIMIDINE 181

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLEOMYCIN authKW 249291 8% 10% 153
2 MIGRASTATIN authKW 153519 1% 91% 10
3 BLEOMYCIN HYDROLASE authKW 147875 1% 52% 17
4 PHENYLACETATE authKW 118183 1% 33% 21
5 ANTINEOPLASTON A10 authKW 101324 0% 100% 6
6 BLEOMYCIN RESISTANCE authKW 90060 0% 67% 8
7 BLEOMYCIN AMPLIFICATION authKW 86847 0% 86% 6
8 BLEOMYCIN BINDING PROTEIN authKW 86847 0% 86% 6
9 ANTINEOPLASTON AS2 1 authKW 84436 0% 100% 5
10 PHENYLBUTYRATE authKW 77140 1% 24% 19

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1624 28% 0% 502
2 Chemistry, Organic 1198 13% 0% 235
3 Pharmacology & Pharmacy 997 16% 0% 287
4 Chemistry, Multidisciplinary 935 17% 0% 310
5 Chemistry, Medicinal 796 7% 0% 125
6 Oncology 719 12% 0% 221
7 Chemistry, Inorganic & Nuclear 418 6% 0% 116
8 Biophysics 272 6% 0% 100
9 Biotechnology & Applied Microbiology 230 6% 0% 113
10 Microbiology 206 6% 0% 107

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOHNS SCI 37995 0% 75% 3
2 EQUIPE ONCOL CELLULAIRE MOL 33775 0% 100% 2
3 COOPERAT DRUG DISCOVERY GRP 21697 0% 14% 9
4 ANALYT CORE IL 16887 0% 100% 1
5 ANTICANC GEORGES FRANCOIS LECLERC 16887 0% 100% 1
6 AREA CRISTALLOG 16887 0% 100% 1
7 BIOCHEM UR 09 09 16887 0% 100% 1
8 BOPHOTON 16887 0% 100% 1
9 BUSINESS MATH TECHNOL 16887 0% 100% 1
10 CHEM NEURODEGENERAT 16887 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ANTIBIOTICS 11654 4% 1% 68
2 DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH 9335 2% 2% 32
3 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2789 7% 0% 127
4 BIOCHEMISTRY 2385 5% 0% 89
5 JOURNAL OF INORGANIC BIOCHEMISTRY 1689 1% 0% 24
6 ANTI-CANCER DRUG DESIGN 1306 0% 1% 7
7 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 1187 1% 1% 12
8 AUSTRALIAN JOURNAL OF CHEMISTRY 1181 1% 0% 23
9 NUKLEARMEDIZIN 1166 0% 1% 5
10 METAL IONS IN BIOLOGICAL SYSTEMS 1005 0% 1% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BLEOMYCIN 249291 8% 10% 153 Search BLEOMYCIN Search BLEOMYCIN
2 MIGRASTATIN 153519 1% 91% 10 Search MIGRASTATIN Search MIGRASTATIN
3 BLEOMYCIN HYDROLASE 147875 1% 52% 17 Search BLEOMYCIN+HYDROLASE Search BLEOMYCIN+HYDROLASE
4 PHENYLACETATE 118183 1% 33% 21 Search PHENYLACETATE Search PHENYLACETATE
5 ANTINEOPLASTON A10 101324 0% 100% 6 Search ANTINEOPLASTON+A10 Search ANTINEOPLASTON+A10
6 BLEOMYCIN RESISTANCE 90060 0% 67% 8 Search BLEOMYCIN+RESISTANCE Search BLEOMYCIN+RESISTANCE
7 BLEOMYCIN AMPLIFICATION 86847 0% 86% 6 Search BLEOMYCIN+AMPLIFICATION Search BLEOMYCIN+AMPLIFICATION
8 BLEOMYCIN BINDING PROTEIN 86847 0% 86% 6 Search BLEOMYCIN+BINDING+PROTEIN Search BLEOMYCIN+BINDING+PROTEIN
9 ANTINEOPLASTON AS2 1 84436 0% 100% 5 Search ANTINEOPLASTON+AS2+1 Search ANTINEOPLASTON+AS2+1
10 PHENYLBUTYRATE 77140 1% 24% 19 Search PHENYLBUTYRATE Search PHENYLBUTYRATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CLAUSSEN, CA , LONG, EC , (1999) NUCLEIC ACID RECOGNITION BY METAL COMPLEXES OF BLEOMYCIN.CHEMICAL REVIEWS. VOL. 99. ISSUE 9. P. 2797 -2816 150 91% 178
2 BOGER, DL , CAI, H , (1999) BLEOMYCIN: SYNTHETIC AND MECHANISTIC STUDIES.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 38. ISSUE 4. P. 448 -476 146 89% 76
3 BURGER, RM , (1998) CLEAVAGE OF NUCLEIC ACIDS BY BLEOMYCIN.CHEMICAL REVIEWS. VOL. 98. ISSUE 3. P. 1153 -1169 109 81% 374
4 SERGEYEV, DS , ZARYTOVA, VF , (1996) INTERACTION OF BLEOMYCIN AND THEIR OLIGONUCLEOTIDE DERIVATIVES WITH NUCLEIC ACIDS.USPEKHI KHIMII. VOL. 65. ISSUE 4. P. 377-402 126 81% 3
5 HECHT, SM , (2000) BLEOMYCIN: NEW PERSPECTIVES ON THE MECHANISM OF ACTION.JOURNAL OF NATURAL PRODUCTS. VOL. 63. ISSUE 1. P. 158 -168 75 79% 279
6 PETERING, DH , BYRNES, RW , ANTHOLINE, WE , (1990) THE ROLE OF REDOX-ACTIVE METALS IN THE MECHANISM OF ACTION OF BLEOMYCIN.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 73. ISSUE 2-3. P. 133-182 118 86% 118
7 LEHMANN, T , TOPCHIY, E , (2013) CONTRIBUTIONS OF NMR TO THE UNDERSTANDING OF THE COORDINATION CHEMISTRY AND DNA INTERACTIONS OF METALLO-BLEOMYCINS.MOLECULES. VOL. 18. ISSUE 8. P. 9253-9277 59 92% 1
8 BOGER, DL , RAMSEY, TM , CAI, H , HOEHN, ST , KOZARICH, JW , STUBBE, J , (1998) ASSESSMENT OF THE ROLE OF THE BLEOMYCIN A(2) PYRIMIDOBLAMIC ACID C4 AMINO GROUP.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. VOL. 120. ISSUE 1. P. 53 -65 78 96% 20
9 STUBBE, J , KOZARICH, JW , WU, W , VANDERWALL, DE , (1996) BLEOMYCINS: A STRUCTURAL MODEL FOR SPECIFICITY, BINDING, AND DOUBLE STRAND CLEAVAGE.ACCOUNTS OF CHEMICAL RESEARCH. VOL. 29. ISSUE 7. P. 322-330 75 86% 182
10 RISHEL, MJ , THOMAS, CJ , TAO, ZF , VIALAS, C , LEITHEISER, CJ , HECHT, SM , (2003) CONFORMATIONALLY CONSTRAINED ANALOGUES OF BLEOMYCIN A(5).JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. VOL. 125. ISSUE 34. P. 10194 -10205 69 91% 13

Classes with closest relation at Level 2


Rank Class id link
1 2856 ARYNES//ENEDIYNE//NEOCARZINOSTATIN
2 1654 DISTAMYCIN//MINOR GROOVE BINDER//PYRROLE IMIDAZOLE POLYAMIDE
3 1439 DNA BINDING//RESONANCE LIGHT SCATTERING//RESONANCE RAYLEIGH SCATTERING
4 3633 GENE POINT MUTATIONS//HETEROKARYON 12//AD 3A LOCUS
5 968 IDIOPATHIC PULMONARY FIBROSIS//INTERSTITIAL LUNG DISEASE//PULMONARY FIBROSIS
6 1228 BASE EXCISION REPAIR//DNA GLYCOSYLASE//OXIDATIVE DNA DAMAGE
7 2441 ELECTROPORATION//ELECTROCHEMOTHERAPY//ELECTROPERMEABILIZATION
8 4152 COOPERAT LIFE SCI//FRONTIER GENOM DRUG DISCOVERY//GLYCOGLYCEROLIPIDS
9 2252 ANGUCYCLINE//IDARUBICIN//ANGUCYCLINONE
10 1531 HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR

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