Class information for:
Level 2: LEVOSIMENDAN//CALCIUM SENSITIZER//MILRINONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2676 3400 31.6 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
62 3       CARDIAC & CARDIOVASCULAR SYSTEM//HEART FAILURE//PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 86105
2676 2             LEVOSIMENDAN//CALCIUM SENSITIZER//MILRINONE 3400
3744 1                   ENOXIMONE//MILRINONE//AMRINONE 1919
10864 1                   LEVOSIMENDAN//CALCIUM SENSITIZER//PIMOBENDAN 1030
23565 1                   VESNARINONE//TSC 22//POSITIVE INOTROPIC ACTIVITY 342
34620 1                   BDF 9148//DPI 201 106//NA CHANNEL ACTIVATOR 109

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEVOSIMENDAN authKW 2913907 11% 85% 383
2 CALCIUM SENSITIZER authKW 648716 3% 85% 85
3 MILRINONE authKW 439541 4% 39% 124
4 ENOXIMONE authKW 363281 2% 65% 62
5 VESNARINONE authKW 344779 1% 80% 48
6 PIMOBENDAN authKW 295511 1% 69% 48
7 AMRINONE authKW 265452 2% 56% 53
8 CA2 SENSITIZER authKW 232802 1% 79% 33
9 TSC 22 authKW 225713 1% 93% 27
10 INOTROPIC AGENTS authKW 216743 2% 30% 80

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cardiac & Cardiovascular System 31981 38% 0% 1302
2 Pharmacology & Pharmacy 12721 37% 0% 1242
3 Anesthesiology 3365 6% 0% 213
4 Chemistry, Medicinal 2860 9% 0% 314
5 Peripheral Vascular Diseases 2284 8% 0% 281
6 Critical Care Medicine 1445 4% 0% 148
7 Respiratory System 635 4% 0% 141
8 Medicine, General & Internal 116 5% 0% 153
9 Physiology 66 3% 0% 88
10 Chemistry, Multidisciplinary 33 5% 0% 185

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CRIT CARE PROPRIETARY PROD 53875 0% 100% 6
2 CARDIOVASC PROJECTS 44896 0% 100% 5
3 CARDIOTHORAC ANAESTHESIA INTENS CARE UNIT 20202 0% 75% 3
4 NAT OURCES FUNCT MOL CHANGBAI MT 19736 0% 20% 11
5 ANAESTHESIA INTENS CAREUMR 942 17958 0% 100% 2
6 ANESTHESIOL SCI CRIT MED PAIN THER Y 17958 0% 100% 2
7 BLOOMSBURY INTENS CARE 17958 0% 100% 2
8 HEART FAILURE CLIN ECHO 17958 0% 100% 2
9 HEART TRANSPLANT CLIN 17958 0% 100% 2
10 SO HLTH EMERGENCY MED TOXICOL GRP 17958 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 46485 7% 2% 239
2 CARDIOVASCULAR DRUGS AND THERAPY 13938 2% 3% 55
3 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 12317 2% 2% 78
4 CARDIOVASCULAR DRUG REVIEWS 8513 1% 5% 20
5 ZEITSCHRIFT FUR KARDIOLOGIE 8185 2% 2% 61
6 AMERICAN HEART JOURNAL 4728 3% 1% 88
7 AMERICAN JOURNAL OF CARDIOLOGY 4453 3% 0% 117
8 JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA 4273 1% 1% 43
9 CIRCULATION 2662 3% 0% 87
10 HERZ KREISLAUF 2628 1% 2% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LEVOSIMENDAN 2913907 11% 85% 383 Search LEVOSIMENDAN Search LEVOSIMENDAN
2 CALCIUM SENSITIZER 648716 3% 85% 85 Search CALCIUM+SENSITIZER Search CALCIUM+SENSITIZER
3 MILRINONE 439541 4% 39% 124 Search MILRINONE Search MILRINONE
4 ENOXIMONE 363281 2% 65% 62 Search ENOXIMONE Search ENOXIMONE
5 VESNARINONE 344779 1% 80% 48 Search VESNARINONE Search VESNARINONE
6 PIMOBENDAN 295511 1% 69% 48 Search PIMOBENDAN Search PIMOBENDAN
7 AMRINONE 265452 2% 56% 53 Search AMRINONE Search AMRINONE
8 CA2 SENSITIZER 232802 1% 79% 33 Search CA2+SENSITIZER Search CA2+SENSITIZER
9 TSC 22 225713 1% 93% 27 Search TSC+22 Search TSC+22
10 INOTROPIC AGENTS 216743 2% 30% 80 Search INOTROPIC+AGENTS Search INOTROPIC+AGENTS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FARMAKIS, D , ALVAREZ, J , BEN GAL, T , BRITO, D , FEDELE, F , FONSECA, C , GORDON, AC , GOTSMAN, I , GROSSINI, E , GUARRACINO, F , ET AL (2016) LEVOSIMENDAN BEYOND INOTROPY AND ACUTE HEART FAILURE: EVIDENCE OF PLEIOTROPIC EFFECTS ON THE HEART AND OTHER ORGANS: AN EXPERT PANEL POSITION PAPER.INTERNATIONAL JOURNAL OF CARDIOLOGY. VOL. 222. ISSUE . P. 303 -312 109 89% 3
2 LANDONI, G , BIONDI-ZOCCAI, G , GRECO, M , GRECO, T , BIGNAMI, E , MORELLI, A , GUARRACINO, F , ZANGRILLO, A , (2012) EFFECTS OF LEVOSIMENDAN ON MORTALITY AND HOSPITALIZATION. A META-ANALYSIS OF RANDOMIZED CONTROLLED STUDIES.CRITICAL CARE MEDICINE. VOL. 40. ISSUE 2. P. 634 -646 77 86% 63
3 PAPP, Z , EDES, I , FRUHWALD, S , DE HERT, SG , SALMENPERA, M , LEPPIKANGAS, H , MEBAZAA, A , LANDONI, G , GROSSINI, E , CAIMMI, P , ET AL (2012) LEVOSIMENDAN: MOLECULAR MECHANISMS AND CLINICAL IMPLICATIONS CONSENSUS OF EXPERTS ON THE MECHANISMS OF ACTION OF LEVOSIMENDAN.INTERNATIONAL JOURNAL OF CARDIOLOGY. VOL. 159. ISSUE 2. P. 82 -87 79 86% 46
4 PAPP, Z , CSAPO, K , POLLESELLO, P , HAIKALA, H , EDES, I , (2005) PHARMACOLOGICAL MECHANISMS CONTRIBUTING TO THE CLINICAL EFFICACY OF LEVOSIMENDAN.CARDIOVASCULAR DRUG REVIEWS. VOL. 23. ISSUE 1. P. 71-98 95 84% 44
5 TOLLER, WG , STRANZ, C , (2006) LEVOSIMENDAN, A NEW INOTROPIC AND VASODILATOR AGENT.ANESTHESIOLOGY. VOL. 104. ISSUE 3. P. 556-569 91 77% 77
6 NIEMINEN, MS , POLLESELLO, P , VAJDA, G , PAPP, Z , (2009) EFFECTS OF LEVOSIMENDAN ON THE ENERGY BALANCE: PRECLINICAL AND CLINICAL EVIDENCE.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 53. ISSUE 4. P. 302 -310 82 85% 11
7 POLLESELLO, P , PAPP, Z , PAPP, JG , (2016) CALCIUM SENSITIZERS: WHAT HAVE WE LEARNED OVER THE LAST 25 YEARS?.INTERNATIONAL JOURNAL OF CARDIOLOGY. VOL. 203. ISSUE . P. 543 -548 54 79% 5
8 MORENO, N , TAVARES-SILVA, M , LOURENCO, AP , OLIVEIRA-PINTO, J , HENRIQUES-COELHO, T , LEITE-MOREIRA, AF , (2014) LEVOSIMENDAN: THE CURRENT SITUATION AND NEW PROSPECTS.REVISTA PORTUGUESA DE CARDIOLOGIA. VOL. 33. ISSUE 12. P. 797 -802 60 94% 1
9 SOEDING, PF , ROYSE, CF , WRIGHT, CE , ROYSE, AG , ANGUS, JA , (2007) INOPROTECTION: THE PERIOPERATIVE ROLE OF LEVOSIMENDAN.ANAESTHESIA AND INTENSIVE CARE. VOL. 35. ISSUE 6. P. 845-862 101 64% 14
10 FISCHER, TA , ERBEL, R , TREESE, N , (1992) CURRENT STATUS OF PHOSPHODIESTERASE INHIBITORS IN THE TREATMENT OF CONGESTIVE-HEART-FAILURE.DRUGS. VOL. 44. ISSUE 6. P. 928-945 120 89% 23

Classes with closest relation at Level 2


Rank Class id link
1 942 HEART FAILURE//ACUTE HEART FAILURE//EUROPEAN JOURNAL OF HEART FAILURE
2 3416 PYRIDAZINONE//PYRIDAZINE//THIENOPYRIDAZINES
3 1338 PHOSPHODIESTERASE//ROLIPRAM//PDE4
4 377 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY//PHOSPHOLAMBAN//CARDIAC & CARDIOVASCULAR SYSTEM
5 1079 BETA3 ADRENOCEPTOR//ADENYLYL CYCLASE//G PROTEIN
6 3846 O ETHYL THIOCARBOXYLATES//LITVINENKO PHYS ORGAN COAL CHEM//THIETHANE
7 2888 HEART KIDNEY//FENOLDOPAM//IBOPAMINE
8 744 SEPSIS//SEPTIC SHOCK//HYDROXYETHYL STARCH
9 2821 NITRATE TOLERANCE//NITROGLYCERIN//ORGANIC NITRATES
10 878 NEBIVOLOL//CARVEDILOL//BETA BLOCKERS

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