Class information for:
Level 1: BDF 9148//DPI 201 106//NA CHANNEL ACTIVATOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
34620 109 31.4 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
62 3       CARDIAC & CARDIOVASCULAR SYSTEM//HEART FAILURE//PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 86105
2676 2             LEVOSIMENDAN//CALCIUM SENSITIZER//MILRINONE 3400
34620 1                   BDF 9148//DPI 201 106//NA CHANNEL ACTIVATOR 109

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BDF 9148 authKW 3050442 13% 78% 14
2 DPI 201 106 authKW 1883176 10% 61% 11
3 NA CHANNEL ACTIVATOR authKW 1120573 4% 100% 4
4 NA CHANNEL MODULATORS authKW 1120573 4% 100% 4
5 BDF 9198 authKW 560286 2% 100% 2
6 SODIUM CHANNEL MODIFYING AGENTS authKW 560286 2% 100% 2
7 POSITIVE INOTROPIC AGENTS authKW 527697 8% 21% 9
8 POSITIVE INOTROPIC COMPOUNDS authKW 373523 2% 67% 2
9 ACQUIRED QT SYNDROME authKW 280143 1% 100% 1
10 BDF 8784 authKW 280143 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1401 65% 0% 71
2 Cardiac & Cardiovascular System 798 34% 0% 37
3 Physiology 96 11% 0% 12
4 Chemistry, Medicinal 5 3% 0% 3
5 Engineering, Biomedical 3 2% 0% 2
6 Cell Biology 2 5% 0% 5
7 Chemistry, Organic 2 4% 0% 4
8 Engineering, Industrial 1 1% 0% 1
9 Peripheral Vascular Diseases 1 2% 0% 2
10 Critical Care Medicine 1 1% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MED CARDIOL MOL PHARMACOL 280143 1% 100% 1
2 PHARMACOL PAHRMACOTHER Y 280143 1% 100% 1
3 CARDIOVASC PHARMACOL GRP 148306 3% 18% 3
4 PHARMACOL 3600 HANDA CHO 140071 1% 50% 1
5 OR HERZMUSKELPHYSIOL MOL KARDIOL 70034 1% 25% 1
6 VET PHARMAKOL 70034 1% 25% 1
7 PHARMAKOL PHARMACOL 56027 1% 20% 1
8 EXPT SURG ANAESTHESIOL 26676 2% 5% 2
9 MUSCLE MOL CARDIOL 25987 3% 3% 3
10 INNERE MED KLIN 3 6770 5% 0% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 8273 17% 0% 18
2 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 2957 7% 0% 8
3 JOURNAL OF ENGINEERING TECHNOLOGY 2239 1% 1% 1
4 BRITISH JOURNAL OF PHARMACOLOGY 1909 10% 0% 11
5 CARDIOVASCULAR DRUGS AND THERAPY 1298 3% 0% 3
6 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 806 4% 0% 4
7 CARDIOVASCULAR DRUG REVIEWS 665 1% 0% 1
8 EUROPEAN JOURNAL OF PHARMACOLOGY 631 7% 0% 8
9 INDUSTRIAL ENGINEERING 594 1% 0% 1
10 JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 537 2% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BDF 9148 3050442 13% 78% 14 Search BDF+9148 Search BDF+9148
2 DPI 201 106 1883176 10% 61% 11 Search DPI+201+106 Search DPI+201+106
3 NA CHANNEL ACTIVATOR 1120573 4% 100% 4 Search NA+CHANNEL+ACTIVATOR Search NA+CHANNEL+ACTIVATOR
4 NA CHANNEL MODULATORS 1120573 4% 100% 4 Search NA+CHANNEL+MODULATORS Search NA+CHANNEL+MODULATORS
5 BDF 9198 560286 2% 100% 2 Search BDF+9198 Search BDF+9198
6 SODIUM CHANNEL MODIFYING AGENTS 560286 2% 100% 2 Search SODIUM+CHANNEL+MODIFYING+AGENTS Search SODIUM+CHANNEL+MODIFYING+AGENTS
7 POSITIVE INOTROPIC AGENTS 527697 8% 21% 9 Search POSITIVE+INOTROPIC+AGENTS Search POSITIVE+INOTROPIC+AGENTS
8 POSITIVE INOTROPIC COMPOUNDS 373523 2% 67% 2 Search POSITIVE+INOTROPIC+COMPOUNDS Search POSITIVE+INOTROPIC+COMPOUNDS
9 ACQUIRED QT SYNDROME 280143 1% 100% 1 Search ACQUIRED+QT+SYNDROME Search ACQUIRED+QT+SYNDROME
10 BDF 8784 280143 1% 100% 1 Search BDF+8784 Search BDF+8784

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RAVENS, U , AMOS, GJ , EHRING, T , HEUSCH, G , (1995) BDF 9148 - A SODIUM CHANNEL MODULATOR WITH POSITIVE INOTROPIC ACTION.CARDIOVASCULAR DRUG REVIEWS. VOL. 13. ISSUE 3. P. 260-274 27 69% 1
2 AMOS, GJ , RAVENS, U , (1994) THE INOTROPIC AGENTS DPI-201-106 AND BDF-9148 DIFFERENTIALLY AFFECT POTASSIUM CURRENTS OF GUINEA-PIG VENTRICULAR MYOCYTES.NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. VOL. 350. ISSUE 4. P. 426-433 21 78% 12
3 SIRCAR, I , HALEEN, SJ , BURKE, SE , BARTH, H , (1992) SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 4-(DIPHENYLMETHYL)-ALPHA-[(4-QUINOLINYLOXY)METHYL]-1-PIPERAZINEETHANOL AND RELATED-COMPOUNDS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 35. ISSUE 23. P. 4442-4449 19 83% 16
4 GILL, RM , JONES, BD , STEINBERG, MI , SHEN, WQ , (2002) A SODIUM CHANNEL ENHANCER, LY341311, INCREASES MYOCARDIAL CONTRACTILE PERFORMANCE WITHOUT INCREASING HEART RATE IN CONSCIOUS NORMAL DOGS: A COMPARISON WITH DOBUTAMINE.JOURNAL OF CARDIAC FAILURE. VOL. 8. ISSUE 1. P. 33-42 14 64% 1
5 RAAP, A , ARMAH, B , MEST, HJ , STENZEL, W , SCHLOOS, J , BLECHACZ, W , (1997) INVESTIGATIONS OF THE MECHANISM OF THE POSITIVE INOTROPIC ACTION OF BDF 9148: COMPARISON WITH DPI 201-106 AND THE ENANTIOMERS.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 29. ISSUE 2. P. 164-173 14 67% 7
6 TANIMURA, M , MISHIMA, T , STEINBERG, MI , BORZAK, S , GOLDSTEIN, S , SABBAH, HN , (2000) HEMODYNAMIC EFFECTS OF A NOVEL SODIUM CHANNEL ACTIVATOR IN DOGS WITH CHRONIC HEART FAILURE.CARDIOVASCULAR DRUGS AND THERAPY. VOL. 14. ISSUE 1. P. 77-82 15 48% 2
7 SHEN, WQ , GILL, RM , ZHANG, JP , JONES, BD , CORBLY, AK , STEINBERG, MI , (2005) SODIUM CHANNEL ENHANCER RESTORES BAROREFLEX SENSITIVITY IN CONSCIOUS DOGS WITH HEART FAILURE.AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. VOL. 288. ISSUE 4. P. H1508-H1514 14 44% 5
8 BRASCH, H , IVEN, H , (1991) INOTROPIC AND ELECTROPHYSIOLOGICAL EFFECTS OF BDF-9148, A CONGENER OF DPI-201-106, IN GUINEA-PIG ATRIA AND PAPILLARY-MUSCLES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 103. ISSUE 4. P. 1939-1945 12 80% 23
9 FLESCH, M , ERDMANN, E , (2001) NA+ CHANNEL ACTIVATORS AS POSITIVE INOTROPIC AGENTS FOR THE TREATMENT OF CHRONIC HEART FAILURE.CARDIOVASCULAR DRUGS AND THERAPY. VOL. 15. ISSUE 5. P. 379-386 10 63% 11
10 HOEY, A , AMOS, GJ , WETTWER, E , RAVENS, U , (1994) DIFFERENTIAL-EFFECTS OF BDF-9148 AND DPI-201-106 ON ACTION-POTENTIAL AND CONTRACTILITY IN RAT AND GUINEA-PIG MYOCARDIUM.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 23. ISSUE 6. P. 907-915 14 56% 14

Classes with closest relation at Level 1


Rank Class id link
1 1563 SODIUM CHANNEL//USE DEPENDENT BLOCK//NA CHANNEL
2 3744 ENOXIMONE//MILRINONE//AMRINONE
3 10864 LEVOSIMENDAN//CALCIUM SENSITIZER//PIMOBENDAN
4 7174 R 56865//DELAYED AFTERDEPOLARIZATION//DIASTOLIC DEPOLARIZATION
5 7162 SOTALOL//DOFETILIDE//CLASS III ANTIARRHYTHMIC AGENT
6 18583 RANOLAZINE//LATE SODIUM CURRENT//LATE I NA
7 6581 BETA ADRENOCEPTOR//BETA ADRENERGIC RECEPTOR SUBTYPES//BETA ADRENERGIC RECEPTOR
8 3746 PHOSPHOLAMBAN//SARCOPLASMIC RETICULUM//PHARMACOL CELL BIOPHYS
9 5719 NA K ATPASE//SODIUM PUMP//RECH CARDIOL
10 4492 DIHYDROPYRIDINE//SR 33557//BAY K 8644

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