Class information for:
Level 2: METFORMIN//ACARBOSE//REPAGLINIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1896 5944 32.1 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
176 3       DIABETES CARE//ENDOCRINOLOGY & METABOLISM//TYPE 2 DIABETES 58057
1896 2             METFORMIN//ACARBOSE//REPAGLINIDE 5944
6705 1                   GLIMEPIRIDE//JTT 608//SECONDARY FAILURE 1453
8357 1                   ACARBOSE//ALPHA GLUCOSIDASE INHIBITOR//MIGLITOL 1262
8850 1                   METFORMIN//LACTIC ACIDOSIS//BIGUANIDES 1211
16225 1                   REPAGLINIDE//NATEGLINIDE//MITIGLINIDE 666
16766 1                   METFORMIN HYDROCHLORIDE//GLIMEPIRIDE//GLICLAZIDE 637
22786 1                   GLICLAZIDE//ARTIFICIAL CELL MICROENCAPSULATION//BIOTECHNOL DRUG DEV 369
23415 1                   INSULIN OVERDOSE//BIOCHEMICAL HYPOGLYCEMIA//LETHAL HYPOGLYCAEMIA 346

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METFORMIN authKW 766423 13% 20% 749
2 ACARBOSE authKW 426751 3% 43% 193
3 REPAGLINIDE authKW 334207 2% 52% 125
4 GLICLAZIDE authKW 325837 2% 46% 138
5 ALPHA GLUCOSIDASE INHIBITOR authKW 323823 3% 37% 170
6 GLIMEPIRIDE authKW 308768 2% 44% 137
7 NATEGLINIDE authKW 294540 2% 59% 97
8 MIGLITOL authKW 212772 1% 70% 59
9 MITIGLINIDE authKW 167667 1% 82% 40
10 ALPHA GLUCOSIDASE authKW 147511 3% 17% 171

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Endocrinology & Metabolism 39658 32% 0% 1892
2 Pharmacology & Pharmacy 8982 24% 0% 1445
3 Medicine, General & Internal 3735 13% 0% 770
4 Chemistry, Analytical 1210 8% 0% 450
5 Chemistry, Medicinal 726 4% 0% 240
6 Nutrition & Dietetics 484 3% 0% 179
7 Biochemical Research Methods 471 4% 0% 234
8 Medicine, Research & Experimental 439 4% 0% 262
9 Food Science & Technology 371 4% 0% 240
10 Integrative & Complementary Medicine 216 1% 0% 52

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTECHNOL DRUG DEV 38673 0% 42% 18
2 PHARMBIOSCI PRECINCT 20541 0% 100% 4
3 BIOTECHNOL DRUG DEV BIOSCI PRECINCT 15406 0% 100% 3
4 HIGASHISONOGI TEA BRANCH 15406 0% 100% 3
5 BIOSCI PRECINCT 13853 0% 30% 9
6 FOOD BIOCHEMKITA KU 13135 0% 32% 8
7 BEZAFIBRATE INFARCT PREVENT COORDINATING 11553 0% 75% 3
8 NAZL INFORMAZ TOSSICOL 11553 0% 75% 3
9 PHARMACEUT REGULATORY AFFAIRS QUAL ASSURANCE DE 11553 0% 75% 3
10 BELGYOGYASZAT DIABETOL 2 10271 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABETES & METABOLISM 48393 3% 6% 164
2 DIABETES CARE 29232 4% 2% 256
3 DIABETES RESEARCH AND CLINICAL PRACTICE 24622 3% 3% 160
4 DIABETES OBESITY & METABOLISM 20464 2% 4% 94
5 DIABETIC MEDICINE 15304 2% 2% 131
6 METABOLISM-CLINICAL AND EXPERIMENTAL 12497 2% 2% 148
7 HORMONE AND METABOLIC RESEARCH 7185 2% 2% 95
8 ACTA DIABETOLOGICA LATINA 6708 0% 5% 24
9 DIABETOLOGIA 4541 1% 1% 87
10 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 3959 1% 1% 75

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METFORMIN 766423 13% 20% 749 Search METFORMIN Search METFORMIN
2 ACARBOSE 426751 3% 43% 193 Search ACARBOSE Search ACARBOSE
3 REPAGLINIDE 334207 2% 52% 125 Search REPAGLINIDE Search REPAGLINIDE
4 GLICLAZIDE 325837 2% 46% 138 Search GLICLAZIDE Search GLICLAZIDE
5 ALPHA GLUCOSIDASE INHIBITOR 323823 3% 37% 170 Search ALPHA+GLUCOSIDASE+INHIBITOR Search ALPHA+GLUCOSIDASE+INHIBITOR
6 GLIMEPIRIDE 308768 2% 44% 137 Search GLIMEPIRIDE Search GLIMEPIRIDE
7 NATEGLINIDE 294540 2% 59% 97 Search NATEGLINIDE Search NATEGLINIDE
8 MIGLITOL 212772 1% 70% 59 Search MIGLITOL Search MIGLITOL
9 MITIGLINIDE 167667 1% 82% 40 Search MITIGLINIDE Search MITIGLINIDE
10 ALPHA GLUCOSIDASE 147511 3% 17% 171 Search ALPHA+GLUCOSIDASE Search ALPHA+GLUCOSIDASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CUSI, K , DEFRONZO, RA , (1998) METFORMIN: A REVIEW OF ITS METABOLIC EFFECTS.DIABETES REVIEWS. VOL. 6. ISSUE 2. P. 89 -131 218 69% 180
2 SALPETER, SR , GREYBER, E , PASTERNAK, GA , SALPETER, EE , (2010) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 4. P. - 199 52% 14
3 RENDELL, M , (2004) THE ROLE OF SULPHONYLUREAS IN THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS.DRUGS. VOL. 64. ISSUE 12. P. 1339-1358 160 60% 145
4 INZUCCHI, SE , LIPSKA, KJ , MAYO, H , BAILEY, CJ , MCGUIRE, DK , (2014) METFORMIN IN PATIENTS WITH TYPE 2 DIABETES AND KIDNEY DISEASE A SYSTEMATIC REVIEW.JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. VOL. 312. ISSUE 24. P. 2668 -2675 60 91% 81
5 DEFRONZO, R , FLEMING, GA , CHEN, K , BICSAK, TA , (2016) METFORMIN-ASSOCIATED LACTIC ACIDOSIS: CURRENT PERSPECTIVES ON CAUSES AND RISK.METABOLISM-CLINICAL AND EXPERIMENTAL. VOL. 65. ISSUE 2. P. 20 -29 60 81% 11
6 SALPETER, SR , GREYBER, E , PASTERNAK, GA , SALPETER, EE , (2003) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS - SYSTEMATIC REVIEW AND META-ANALYSIS.ARCHIVES OF INTERNAL MEDICINE. VOL. 163. ISSUE 21. P. 2594-2602 121 79% 128
7 SALPETER, S , GREYBER, E , PASTERNAK, G , SALPETER, E , (2003) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 3. P. - 138 78% 20
8 CALELLO, DP , LIU, KD , WIEGAND, TJ , ROBERTS, DM , LAVERGNE, V , GOSSELIN, S , HOFFMAN, RS , NOLIN, TD , GHANNOUM, M , (2015) EXTRACORPOREAL TREATMENT FOR METFORMIN POISONING: SYSTEMATIC REVIEW AND RECOMMENDATIONS FROM THE EXTRACORPOREAL TREATMENTS IN POISONING WORKGROUP.CRITICAL CARE MEDICINE. VOL. 43. ISSUE 8. P. 1716 -1730 86 80% 6
9 HOWLETT, HCS , BAILEY, CJ , (1999) A RISK-BENEFIT ASSESSMENT OF METFORMIN IN TYPE 2 DIABETES MELLITUS.DRUG SAFETY. VOL. 20. ISSUE 6. P. 489 -503 103 76% 108
10 KAJBAF, F , DE BROE, ME , LALAU, JD , (2016) THERAPEUTIC CONCENTRATIONS OF METFORMIN: A SYSTEMATIC REVIEW.CLINICAL PHARMACOKINETICS. VOL. 55. ISSUE 4. P. 439 -459 83 69% 0

Classes with closest relation at Level 2


Rank Class id link
1 1167 GLUCAGON LIKE PEPTIDE 1//GLP 1//INCRETIN
2 1300 THIAZOLIDINEDIONES//PPAR GAMMA//ROSIGLITAZONE
3 79 DIABETES CARE//DIABETES EDUCATOR//DIABETIC MEDICINE
4 497 METABOLIC SYNDROME//WAIST CIRCUMFERENCE//INSULIN RESISTANCE
5 1552 INSULIN RECEPTOR//INSULIN DEGRADING ENZYME//INOSITOL PHOSPHOGLYCAN
6 1189 NICORANDIL//ISCHEMIC PRECONDITIONING//K ATP CHANNEL
7 457 BETA CELL//INSULIN SECRETION//PANCREATIC ISLETS
8 2357 PEUTZ JEGHERS SYNDROME//AMPK//LKB1
9 684 GLUT4//AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM//GLUCOSE TRANSPORT
10 1155 PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1

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