Class information for:
Level 1: LEHRSTUHL PHARMAZEUT CHEM 2//GRP RECH ONCOL ENDOCRINOL MOL//PORPHYRIN PLATINUM CONJUGATES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20988 437 29.6 55%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
489 3       CISPLATIN//STABILITY CONSTANTS//JOURNAL OF INORGANIC BIOCHEMISTRY 23107
1065 2             CISPLATIN//NEPHROTOXICITY//PLATINUMII COMPLEXES 9996
20988 1                   LEHRSTUHL PHARMAZEUT CHEM 2//GRP RECH ONCOL ENDOCRINOL MOL//PORPHYRIN PLATINUM CONJUGATES 437

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEHRSTUHL PHARMAZEUT CHEM 2 address 773987 3% 92% 12
2 GRP RECH ONCOL ENDOCRINOL MOL address 343989 2% 62% 8
3 PORPHYRIN PLATINUM CONJUGATES authKW 279496 1% 100% 4
4 ESTROGEN RECEPTOR AFFINITY authKW 223595 1% 80% 4
5 ESTROGEN RECEPTOR TARGETED DELIVERY OF PHOTOTOXINS authKW 209622 1% 100% 3
6 ZINDOXIFENE authKW 209622 1% 100% 3
7 1 2 BIS2 6 DIFLUORO 3 HYDROXYPHENYLETHYLENEDIAMINEPLATINUMII COMPLEXES authKW 139748 0% 100% 2
8 LEHRSTUHL PHARMACEUT CHEM 2 address 139748 0% 100% 2
9 MESO 1 2 BIS2 6 DICHLORO 4 HYDROXYPHENYLETHYLENEDIAMINEDICHLOROPLATINUMII authKW 139748 0% 100% 2
10 MXT M 3 2 BREAST CANCER authKW 139748 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 8683 42% 0% 182
2 Chemistry, Multidisciplinary 713 28% 0% 121
3 Pharmacology & Pharmacy 643 24% 0% 105
4 Chemistry, Inorganic & Nuclear 560 14% 0% 59
5 Oncology 270 15% 0% 64
6 Chemistry, Organic 257 12% 0% 54
7 Biochemistry & Molecular Biology 54 14% 0% 60
8 Endocrinology & Metabolism 42 5% 0% 22
9 Chemistry, Analytical 12 4% 0% 17
10 Biochemical Research Methods 4 2% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEHRSTUHL PHARMAZEUT CHEM 2 773987 3% 92% 12
2 GRP RECH ONCOL ENDOCRINOL MOL 343989 2% 62% 8
3 LEHRSTUHL PHARMACEUT CHEM 2 139748 0% 100% 2
4 SERV MED CANCEROL MAMMAIRE 139748 0% 100% 2
5 GRP RECH BIOPATHOL CELLULAI MOL 101630 1% 36% 4
6 DIPATIMENTO SCI CHIM FIS MATEMAT 69874 0% 100% 1
7 GRP RECH BIOPHATOL CELLULAI MOL 69874 0% 100% 1
8 NPO ORGAN INTERMEDIATES DYES 69874 0% 100% 1
9 PHARMAZEUT CHEM 2 69874 0% 100% 1
10 PHARMAZEUT MED CHEM 2 69874 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARCHIV DER PHARMAZIE 93950 17% 2% 76
2 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 12216 7% 1% 29
3 JOURNAL OF MEDICINAL CHEMISTRY 6575 10% 0% 45
4 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2687 4% 0% 19
5 INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY 1962 1% 1% 5
6 ANTI-CANCER DRUG DESIGN 1775 1% 1% 4
7 INORGANICA CHIMICA ACTA 909 3% 0% 15
8 CANCER TREATMENT REVIEWS 891 1% 0% 5
9 MONATSHEFTE FUR CHEMIE 716 2% 0% 8
10 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 614 2% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PORPHYRIN PLATINUM CONJUGATES 279496 1% 100% 4 Search PORPHYRIN+PLATINUM+CONJUGATES Search PORPHYRIN+PLATINUM+CONJUGATES
2 ESTROGEN RECEPTOR AFFINITY 223595 1% 80% 4 Search ESTROGEN+RECEPTOR+AFFINITY Search ESTROGEN+RECEPTOR+AFFINITY
3 ESTROGEN RECEPTOR TARGETED DELIVERY OF PHOTOTOXINS 209622 1% 100% 3 Search ESTROGEN+RECEPTOR+TARGETED+DELIVERY+OF+PHOTOTOXINS Search ESTROGEN+RECEPTOR+TARGETED+DELIVERY+OF+PHOTOTOXINS
4 ZINDOXIFENE 209622 1% 100% 3 Search ZINDOXIFENE Search ZINDOXIFENE
5 1 2 BIS2 6 DIFLUORO 3 HYDROXYPHENYLETHYLENEDIAMINEPLATINUMII COMPLEXES 139748 0% 100% 2 Search 1+2+BIS2+6+DIFLUORO+3+HYDROXYPHENYLETHYLENEDIAMINEPLATINUMII+COMPLEXES Search 1+2+BIS2+6+DIFLUORO+3+HYDROXYPHENYLETHYLENEDIAMINEPLATINUMII+COMPLEXES
6 MESO 1 2 BIS2 6 DICHLORO 4 HYDROXYPHENYLETHYLENEDIAMINEDICHLOROPLATINUMII 139748 0% 100% 2 Search MESO+1+2+BIS2+6+DICHLORO+4+HYDROXYPHENYLETHYLENEDIAMINEDICHLOROPLATINUMII Search MESO+1+2+BIS2+6+DICHLORO+4+HYDROXYPHENYLETHYLENEDIAMINEDICHLOROPLATINUMII
7 MXT M 3 2 BREAST CANCER 139748 0% 100% 2 Search MXT+M+3+2+BREAST+CANCER Search MXT+M+3+2+BREAST+CANCER
8 SALOPHENE 93164 0% 67% 2 Search SALOPHENE Search SALOPHENE
9 1 1 BIS4 HYDROXYPHENYL 2 PHENYLETHENE 69874 0% 100% 1 Search 1+1+BIS4+HYDROXYPHENYL+2+PHENYLETHENE Search 1+1+BIS4+HYDROXYPHENYL+2+PHENYLETHENE
10 1 2 6 DICHLORO 4 HYDROXYPHENYL 2 PHENYLETHANES 69874 0% 100% 1 Search 1+2+6+DICHLORO+4+HYDROXYPHENYL+2+PHENYLETHANES Search 1+2+6+DICHLORO+4+HYDROXYPHENYL+2+PHENYLETHANES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GUST, R , BECK, W , JAOUEN, G , SCHONENBERGER, H , (2009) OPTIMIZATION OF CISPLATIN FOR THE TREATMENT OF HORMONE-DEPENDENT TUMORAL DISEASES PART 2: USE OF NON-STEROIDAL LIGANDS.COORDINATION CHEMISTRY REVIEWS. VOL. 253. ISSUE 21-22. P. 2760-2779 93 82% 22
2 GUST, R , BECK, W , JAOUEN, G , SCHONENBERGER, H , (2009) OPTIMIZATION OF CISPLATIN FOR THE TREATMENT OF HORMONE DEPENDENT TUMORAL DISEASES PART 1: USE OF STEROIDAL LIGANDS.COORDINATION CHEMISTRY REVIEWS. VOL. 253. ISSUE 21-22. P. 2742 -2759 52 42% 44
3 GUST, R , NIEBLER, K , SCHONENBERGER, H , (2005) [N-ETHYL- AND [N,N '-DIETHYL-1,2-BIS(2,6-DIFLUORO-3-HYDROXYPHENYL)-ETHYLENEDIAMINE]DICHLOROPLATINUM(II): STRUCTURE AND CYTOTOXIC/ESTROGENIC ACTIVITY IN BREAST CANCER CELLS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 48. ISSUE 23. P. 7132 -7144 26 65% 7
4 SCHERTL, S , HARTMANN, RW , BATZL-HARTMANN, C , SCHLEMMER, R , SPRUSS, T , BERNHARDT, G , GUST, R , SCHONENBERGER, H , (2001) 1-(2,6-DICHLORO-4-HYDROXYPHENYL)-2-PHENYLETHANES - NEW BIOLOGICAL RESPONSE MODIFIERS FOR THE THERAPY OF BREAST CANCER. SYNTHESIS AND EVALUATION OF ESTROGENIC/ANTIESTROGENIC PROPERTIES.ARCHIV DER PHARMAZIE. VOL. 334. ISSUE 4. P. 125-137 17 100% 4
5 SCHLEMMER, R , SPRUSS, T , BERNHARDT, G , SCHONENBERGER, H , (1999) [MESO-1,2-BIS(2,6-DICHLORO-4-HYDROXYPHENYL)ETHYLENEDIAMINE]DICHLOROPLATINUM(II), A COMPOUND WITH A SPECIFIC ACTIVITY ON HORMONE-SENSITIVE BREAST CANCERS - EVIDENCE FOR A DIETHYLSTILBESTROL-LIKE MODE OF ACTION.ARCHIV DER PHARMAZIE. VOL. 332. ISSUE 2. P. 59-69 22 79% 7
6 SCHERTL, S , HARTMANN, RW , BATZL-HARTMANN, C , BERNHARDT, G , SPRUSS, T , BECKENLEHNER, K , KOCH, M , KRAUSER, R , SCHLEMMER, R , GUST, R , ET AL (2004) [1,2-BIS(2,6-DIFLUORO-3-HYDROXYPHENYL)ETHYLENEDIAMINE]PLATINUM(II) COMPLEXES, COMPOUNDS FOR THE ENDOCRINE THERAPY OF BREAST CANCER - MODE OF ACTION I: ANTITUMOR ACTIVITY DUE TO THE REDUCTION OF THE ENDOGENOUS ESTROGEN LEVEL.ARCHIV DER PHARMAZIE. VOL. 337. ISSUE 6. P. 335-348 24 56% 10
7 DOLOTOVA, O , KALIYA, OL , (2011) DEVELOPMENT OF THE SYNTHESIS OF THE DIAMINE COMPLEXES OF COVALENT CONJUGATES OF PLATINUM(II) WITH OCTACARBOXY-SUBSTITUTED COBALT PHTHALOCYANINE.JOURNAL OF PORPHYRINS AND PHTHALOCYANINES. VOL. 15. ISSUE 7-8. P. 632 -638 13 81% 5
8 WURTENBERGER, I , ANGERRNAIER, B , KIRCHER, B , GUST, R , (2013) SYNTHESIS AND IN VITRO PHARMACOLOGICAL BEHAVIOR OF PLATINUM(II) COMPLEXES CONTAINING 1,2-DIAMINO-1-(4-FLUOROPHENYL)-2-ALKANOL LIGANDS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 56. ISSUE 20. P. 7951-7964 16 59% 7
9 KAMMERMEIER, T , WIEGREBE, W , (1995) 1,3-DIPHENYLPROPANE-1,3-DIAMINES .5. DNA-INTERACTION, ESTROGEN-RECEPTOR AFFINITY, AND CYTOSTATIC ACTIVITY OF 1,3-DIPHENYLPROPANE-1,3-DIAMINE-PT(II) COMPLEXES.ARCHIV DER PHARMAZIE. VOL. 328. ISSUE 5. P. 409-415 24 65% 8
10 GUST, R , FADERL, M , SCHONENBERGER, H , (2000) [AQUA-1-(2,6-DICHLORO-4-HYDROXYPHENYL)-2-PHENYLETHYLENEDIAMINE] SULFATOPLATINUM(II) COMPLEXES WITH VARIABLE SUBSTITUENTS IN THE 2-PHENYL RING - 3. INVESTIGATION OF BREAST CANCER INHIBITING PROPERTIES.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. VOL. 126. ISSUE 11. P. 647-654 13 100% 6

Classes with closest relation at Level 1


Rank Class id link
1 12278 SERAM//MATH CHEM//RELATIVE BINDING AFFINITY
2 5771 ANTIESTROGEN//ANTIESTROGEN BINDING SITES//AEBS
3 5887 SATRAPLATIN//JM216//PLATINUM BASED DRUG
4 16557 FLUOROESTRADIOL//F 18 FES PET//F 18FES
5 879 TRANSPLATIN//TRANSPLATINUM//BBR3464
6 27087 HOMO AZA STEROIDAL ESTERS//STEROIDAL ESTERS//HOMO AZA STEROIDS
7 32397 TYPE II H 3ESTRADIOL BINDING SITES//TYPE II SITES//GYNAECOL LARGO A GEMELLI 8
8 32170 ACETYLENIC SULFONE//ALKYL DIACYL PEROXIDES//ALKYNYL KETONES SULFONES
9 37260 PHARM TENPA KU//2 METHYLTHIOETHYL 6 BROMO 1 2 DIHYDRO 6 METHYL 2 OXOSPIRO4 CYCLOHEXENE 1 3 3HINDOLE 2 CARBOXYLATE//BROMO PHENOL
10 8290 BIOORGANOMETALLIC CHEMISTRY//FERROCENE//UMR 7576

Go to start page