Class information for:
Level 1: IMMUNOTOXIN//GELONIN//RICIN A CHAIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6520 1474 36.3 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
103 3       O GLCNACYLATION//O GLCNAC TRANSFERASE//O GLCNACASE 73436
1876 2             RIBOSOME INACTIVATING PROTEIN//RICIN//TRICHOSANTHIN 6016
6520 1                   IMMUNOTOXIN//GELONIN//RICIN A CHAIN 1474

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMMUNOTOXIN authKW 482116 9% 18% 131
2 GELONIN authKW 189358 2% 38% 24
3 RICIN A CHAIN authKW 97086 1% 25% 19
4 LIPOSOMAL RICIN authKW 82857 0% 100% 4
5 IMMUNOCONJUGATE authKW 78069 2% 13% 29
6 LIPOSOMAL MONENSIN authKW 62143 0% 100% 3
7 MONOCLONAL ANTIBODY 80G authKW 62143 0% 100% 3
8 REPROD 110 PINE AVE W address 50741 0% 35% 7
9 ANTI B4 BLOCKED RICIN authKW 46606 0% 75% 3
10 MISSILE THERAPY authKW 46606 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 9619 42% 0% 621
2 Immunology 3217 23% 0% 346
3 Hematology 1061 9% 0% 131
4 Biochemical Research Methods 408 6% 0% 95
5 Biochemistry & Molecular Biology 346 17% 0% 249
6 Pharmacology & Pharmacy 262 10% 0% 152
7 Medicine, Research & Experimental 129 5% 0% 69
8 Transplantation 83 2% 0% 29
9 Biophysics 79 4% 0% 56
10 Chemistry, Medicinal 49 3% 0% 37

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REPROD 110 PINE AVE W 50741 0% 35% 7
2 HEMATOL ONCOL UNIT COX 2 41429 0% 100% 2
3 SELF ORGANISING SYST BIOPHYS 39829 0% 38% 5
4 SIMON FLAVELL LEUKAEMIA UNIT 31068 0% 50% 3
5 HORMONE BIOCHEM 24046 0% 19% 6
6 BIOCHEM CRC MOLEC TOXICOL GRP 20714 0% 100% 1
7 HONGO 731BUNKYO KU 20714 0% 100% 1
8 IDA M GREEN CANC 20714 0% 100% 1
9 IMMUNOL SECT DRUG TARGETING GRP 15 COTSWOLD RD 20714 0% 100% 1
10 MED MED PATHOL CANC 20714 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER IMMUNOLOGY IMMUNOTHERAPY 26768 5% 2% 75
2 CANCER RESEARCH 14372 11% 0% 165
3 ANTIBODY IMMUNOCONJUGATES AND RADIOPHARMACEUTICALS 10214 1% 5% 9
4 CANCER DRUG DELIVERY 8737 0% 6% 7
5 BIOCONJUGATE CHEMISTRY 7275 3% 1% 42
6 CRC CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS 3311 0% 8% 2
7 INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY 3282 1% 1% 18
8 INTERNATIONAL JOURNAL OF CANCER 3262 4% 0% 57
9 JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS 2706 1% 2% 8
10 BRITISH JOURNAL OF CANCER 2598 3% 0% 48

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IMMUNOTOXIN 482116 9% 18% 131 Search IMMUNOTOXIN Search IMMUNOTOXIN
2 GELONIN 189358 2% 38% 24 Search GELONIN Search GELONIN
3 RICIN A CHAIN 97086 1% 25% 19 Search RICIN+A+CHAIN Search RICIN+A+CHAIN
4 LIPOSOMAL RICIN 82857 0% 100% 4 Search LIPOSOMAL+RICIN Search LIPOSOMAL+RICIN
5 IMMUNOCONJUGATE 78069 2% 13% 29 Search IMMUNOCONJUGATE Search IMMUNOCONJUGATE
6 LIPOSOMAL MONENSIN 62143 0% 100% 3 Search LIPOSOMAL+MONENSIN Search LIPOSOMAL+MONENSIN
7 MONOCLONAL ANTIBODY 80G 62143 0% 100% 3 Search MONOCLONAL+ANTIBODY+80G Search MONOCLONAL+ANTIBODY+80G
8 ANTI B4 BLOCKED RICIN 46606 0% 75% 3 Search ANTI+B4+BLOCKED+RICIN Search ANTI+B4+BLOCKED+RICIN
9 MISSILE THERAPY 46606 0% 75% 3 Search MISSILE+THERAPY Search MISSILE+THERAPY
10 CYTOTOXIC ANTI NEOPLASTIC POTENCY 41429 0% 100% 2 Search CYTOTOXIC+ANTI+NEOPLASTIC+POTENCY Search CYTOTOXIC+ANTI+NEOPLASTIC+POTENCY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GILABERT-ORIOL, R , WENG, A , VON MALLINCKRODT, B , MELZIG, MF , FUCHS, H , THAKUR, M , (2014) IMMUNOTOXINS CONSTRUCTED WITH RIBOSOME-INACTIVATING PROTEINS AND THEIR ENHANCERS: A LETHAL COCKTAIL WITH TUMOR SPECIFIC EFFICACY.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 42. P. 6584 -6643 229 32% 14
2 BOLOGNESI, A , POLITO, L , (2004) IMMUNOTOXINS AND OTHER CONJUGATES: PRE-CLINICAL STUDIES.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 5. P. 563 -583 146 67% 40
3 FRACASSO, G , BELLISOLA, G , CASTELLETTI, D , TRIDENTE, G , COLOMBATTI, M , (2004) IMMUNOTOXINS AND OTHER CONJUGATES: PREPARATION AND GENERAL CHARACTERISTICS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 5. P. 545 -562 105 58% 20
4 KREITMAN, RJ , PASTAN, I , (1998) IMMUNOTOXINS FOR TARGETED CANCER THERAPY.ADVANCED DRUG DELIVERY REVIEWS. VOL. 31. ISSUE 1-2. P. 53 -88 157 38% 56
5 GARNETT, MC , (2001) TARGETED DRUG CONJUGATES: PRINCIPLES AND PROGRESS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 53. ISSUE 2. P. 171 -216 82 45% 168
6 ENGERT, A , SAUSVILLE, EA , VITETTA, E , (1998) THE EMERGING ROLE OF RICIN A-CHAIN IMMUNOTOXINS IN LEUKEMIA AND LYMPHOMA.CLINICAL APPLICATIONS OF IMMUNOTOXINS. VOL. 234. ISSUE . P. 13 -33 70 68% 19
7 GHETIE, V , VITETTA, E , (1994) IMMUNOTOXINS IN THE THERAPY OF CANCER - FROM BENCH TO CLINIC.PHARMACOLOGY & THERAPEUTICS. VOL. 63. ISSUE 3. P. 209-234 77 71% 30
8 BLAKEY, DC , WAWRZYNCZAK, EJ , WALLACE, PM , THORPE, PE , (1988) ANTIBODY TOXIN CONJUGATES - A PERSPECTIVE.PROGRESS IN ALLERGY. VOL. 45. ISSUE . P. 50-90 101 65% 43
9 PIETERSZ, GA , ROWLAND, A , SMYTH, MJ , MCKENZIE, IFC , (1994) CHEMOIMMUNOCONJUGATES FOR THE TREATMENT OF CANCER.ADVANCES IN IMMUNOLOGY, VOLUME 56. VOL. 56. ISSUE . P. 301-387 104 40% 27
10 UPESLACIS, J , HINMAN, L , (1988) CHEMICAL MODIFICATION OF ANTIBODIES FOR CANCER-CHEMOTHERAPY.ANNUAL REPORTS IN MEDICINAL CHEMISTRY. VOL. 23. ISSUE . P. 151-160 68 81% 20

Classes with closest relation at Level 1


Rank Class id link
1 7843 DIPHTHERIA TOXIN//PSEUDOMONAS EXOTOXIN//IMMUNOTOXIN
2 2245 RIBOSOME INACTIVATING PROTEIN//RICIN//TRICHOSANTHIN
3 26433 6 MALEIMIDOCAPROYLHYDRAZONE DERIVATIVE OF DOXORUBICIN//METHOTREXATE ALBUMIN//256 CARCINOSARCOMA WALKER
4 411 RADIOIMMUNOTHERAPY//ANTIBODY IMMUNOCONJUGATES AND RADIOPHARMACEUTICALS//IMMUNOSCINTIGRAPHY
5 11281 ANTIBODY DRUG CONJUGATE//GEMTUZUMAB OZOGAMICIN//MYLOTARG
6 11117 BONE MARROW PURGING//BONE MARROW TRANSPLANTATION//POST GRAFT HEMATOPOIESIS
7 13420 NG2 PROTEOGLYCAN//PERICYTE ENDOTHELIAL CELL INTERACTION//POLYVALENT ANTIGEN
8 15463 STEM CELL TRANSPLANTAT PROGRAMME//BONE MARROW TRANSPLANTATION//CD6 ANTIBODY
9 9947 BISPECIFIC ANTIBODY//BISPECIFIC ANTIBODIES//CATUMAXOMAB
10 35878 CHOLESTEROL CONTENT MODIFICATION//ELIMINATION OF HIV 1 INFECTED CELLS//HIGH ALTITUDE PHYSIOL EXPT PATHOL

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