Class information for:
Level 1: PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//NUCLEOSIDE HYDROLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9868 1113 34.7 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
3291 2             PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//METHIONINE DEPENDENCE 1872
9868 1                   PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//NUCLEOSIDE HYDROLASE 1113

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PURINE NUCLEOSIDE PHOSPHORYLASE authKW 1829864 11% 53% 126
2 CARBOHYDRATE CHEM TEAM address 589779 4% 50% 43
3 NUCLEOSIDE HYDROLASE authKW 441531 2% 62% 26
4 NUCLEOSIDE PHOSPHORYLASE authKW 433134 3% 53% 30
5 BIOQUIM ESTRUTURAL address 370345 2% 75% 18
6 INVEST BIOTECNOL SUSTENTABLE LIBIOS address 222210 1% 90% 9
7 DIPARTIMENTO BIOCHIM BIOFIS F CEDRANGOLO address 171701 1% 48% 13
8 PNP authKW 166298 2% 25% 24
9 8 AZAPURINES authKW 146307 1% 67% 8
10 PROGRAMA POS MED CIENCIAS SAUDE address 141220 2% 23% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 4623 53% 0% 594
2 Biophysics 956 12% 0% 128
3 Chemistry, Medicinal 843 9% 0% 98
4 Chemistry, Organic 638 12% 0% 136
5 Biotechnology & Applied Microbiology 387 9% 0% 103
6 Biochemical Research Methods 234 6% 0% 64
7 Chemistry, Multidisciplinary 107 9% 0% 105
8 Crystallography 102 3% 0% 36
9 Pharmacology & Pharmacy 99 8% 0% 91
10 Chemistry, Applied 54 3% 0% 32

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARBOHYDRATE CHEM TEAM 589779 4% 50% 43
2 BIOQUIM ESTRUTURAL 370345 2% 75% 18
3 INVEST BIOTECNOL SUSTENTABLE LIBIOS 222210 1% 90% 9
4 DIPARTIMENTO BIOCHIM BIOFIS F CEDRANGOLO 171701 1% 48% 13
5 PROGRAMA POS MED CIENCIAS SAUDE 141220 2% 23% 22
6 REDE BRASILEIRA PESQUISAS TB 123448 1% 75% 6
7 ITALIAN BIOCATALYSIS 88873 1% 36% 9
8 BIOCRYSTALLOG UNIT 83597 1% 38% 8
9 STRUCT BIOL ZOOCHEM CEIS 82301 0% 100% 3
10 PESQUISAS BIOL MOL FUNC 66937 1% 20% 12

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 9364 4% 1% 40
2 BIOCHEMISTRY 4357 8% 0% 93
3 CURRENT DRUG TARGETS 2922 1% 1% 14
4 AGRICULTURAL AND BIOLOGICAL CHEMISTRY 2420 2% 0% 25
5 JOURNAL OF CARBOHYDRATES-NUCLEOSIDES-NUCLEOTIDES 1888 0% 3% 2
6 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 1774 2% 0% 17
7 BIOCATALYSIS AND BIOTRANSFORMATION 1454 1% 1% 7
8 JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 1336 1% 0% 13
9 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1038 1% 0% 11
10 JOURNAL OF MEDICINAL CHEMISTRY 958 3% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PURINE NUCLEOSIDE PHOSPHORYLASE 1829864 11% 53% 126 Search PURINE+NUCLEOSIDE+PHOSPHORYLASE Search PURINE+NUCLEOSIDE+PHOSPHORYLASE
2 NUCLEOSIDE HYDROLASE 441531 2% 62% 26 Search NUCLEOSIDE+HYDROLASE Search NUCLEOSIDE+HYDROLASE
3 NUCLEOSIDE PHOSPHORYLASE 433134 3% 53% 30 Search NUCLEOSIDE+PHOSPHORYLASE Search NUCLEOSIDE+PHOSPHORYLASE
4 PNP 166298 2% 25% 24 Search PNP Search PNP
5 8 AZAPURINES 146307 1% 67% 8 Search 8+AZAPURINES Search 8+AZAPURINES
6 N DEOXYRIBOSYLTRANSFERASE 137168 0% 100% 5 Search N+DEOXYRIBOSYLTRANSFERASE Search N+DEOXYRIBOSYLTRANSFERASE
7 5 DEOXY 5 METHYLTHIOADENOSINE PHOSPHORYLASE 109734 0% 100% 4 Search 5+DEOXY+5+METHYLTHIOADENOSINE+PHOSPHORYLASE Search 5+DEOXY+5+METHYLTHIOADENOSINE+PHOSPHORYLASE
8 BCX 1777 109734 0% 100% 4 Search BCX+1777 Search BCX+1777
9 FUTALOSINE PATHWAY 109734 0% 100% 4 Search FUTALOSINE+PATHWAY Search FUTALOSINE+PATHWAY
10 IMINORIBITOLS 109734 0% 100% 4 Search IMINORIBITOLS Search IMINORIBITOLS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BZOWSKA, A , KULIKOWSKA, E , SHUGAR, D , (2000) PURINE NUCLEOSIDE PHOSPHORYLASES: PROPERTIES, FUNCTIONS, AND CLINICAL ASPECTS.PHARMACOLOGY & THERAPEUTICS. VOL. 88. ISSUE 3. P. 349 -425 142 48% 270
2 SILVA, RG , NUNES, JES , CANDURI, F , BORGES, JC , GAVA, LM , MORENO, FB , BASSO, LA , SANTOS, DS , (2007) PURINE NUCLEOSIDE PHOSPHORYLASE: A POTENTIAL TARGET FOR THE DEVELOPMENT OF DRUGS TO TREAT T-CELL- AND APICOMPLEXAN PARASITE-MEDIATED DISEASES.CURRENT DRUG TARGETS. VOL. 8. ISSUE 3. P. 413 -422 64 84% 12
3 EVANS, GB , SCHRAMM, VL , TYLER, PC , (2015) THE IMMUCILLINS: DESIGN, SYNTHESIS AND APPLICATION OF TRANSITION-STATE ANALOGUES.CURRENT MEDICINAL CHEMISTRY. VOL. 22. ISSUE 34. P. 3897 -3909 47 84% 0
4 SCHRAMM, VL , (2013) TRANSITION STATES, ANALOGUES, AND DRUG DEVELOPMENT.ACS CHEMICAL BIOLOGY. VOL. 8. ISSUE 1. P. 71-81 45 61% 36
5 FRESCO-TABOADA, A , DE LA MATA, I , ARROYO, M , FERNANDEZ-LUCAS, J , (2013) NEW INSIGHTS ON NUCLEOSIDE 2 '-DEOXYRIBOSYLTRANSFERASES: A VERSATILE BIOCATALYST FOR ONE-POT ONE-STEP SYNTHESIS OF NUCLEOSIDE ANALOGS.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 97. ISSUE 9. P. 3773-3785 41 69% 9
6 SCHRAMM, VL , (2011) ENZYMATIC TRANSITION STATES, TRANSITION-STATE ANALOGS, DYNAMICS, THERMODYNAMICS, AND LIFETIMES.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80. VOL. 80. ISSUE . P. 703 -732 49 48% 84
7 MIKHAILOPULO, IA , (2007) BIOTECHNOLOGY OF NUCLEIC ACID CONSTITUENTS - STATE OF THE ART AND PERSPECTIVES.CURRENT ORGANIC CHEMISTRY. VOL. 11. ISSUE 4. P. 317-333 52 59% 34
8 NAMANJA-MAGLIANO, HA , STRATTON, CF , SCHRAMM, VL , (2016) TRANSITION STATE STRUCTURE AND INHIBITION OF RV0091, A 5 '-DEOXYADENOSINE/5 '-METHYLTHIOADENOSINE NUCLEOSIDASE FROM MYCOBACTERIUM TUBERCULOSIS.ACS CHEMICAL BIOLOGY. VOL. 11. ISSUE 6. P. 1669 -1676 32 80% 0
9 LUO, M , LI, L , SCHRAMM, VL , (2008) REMOTE MUTATIONS ALTER TRANSITION-STATE STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE.BIOCHEMISTRY. VOL. 47. ISSUE 8. P. 2565-2576 35 85% 9
10 RINGIA, EAT , SCHRAMM, VL , (2005) TRANSITION STATES AND INHIBITORS OF THE PURINE NUCLEOSIDE PHOSPHORYLASE FAMILY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 5. ISSUE 13. P. 1237-1258 42 75% 28

Classes with closest relation at Level 1


Rank Class id link
1 15693 PHOSPHORIBOSYLTRANSFERASE//MOL PARASITOL DRUG DESIGN//PURINE SALVAGE
2 22214 MTAP//METHYLTHIOADENOSINE PHOSPHORYLASE//METHIONINE SALVAGE PATHWAY
3 37706 INDOLONE N OXIDES//2 2 PYRIDYLISATOGEN//ISATOGENS
4 33946 QUIM MED COMPUTAC//BIOTECNOL MOL ESTRUTURAL//GRP QUIM MED PROD NAT
5 17105 HYDROGEN TUNNELLING//PROMOTING VIBRATION//HYDROGEN TUNNELING
6 36622 FINE CHEM BIOCHEM//NAMALWA KJM 1//NAMALWA KJM 1 CELLS
7 5370 ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1
8 13135 CLOFARABINE//CLADRIBINE//2 CHLORODEOXYADENOSINE
9 11797 THYMIDINE PHOSPHORYLASE//PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR//TAS 102
10 5118 NUCLEOSIDES & NUCLEOTIDES//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//KETONUCLEOSIDES

Go to start page