Class information for:
Level 1: URSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLIC ACID//BILE ACIDS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9757 1123 42.6 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
212 3       GASTROENTEROLOGY & HEPATOLOGY//LAPAROSCOPIC CHOLECYSTECTOMY//PRIMARY BILIARY CIRRHOSIS 51420
1019 2             BILE ACIDS//FARNESOID X RECEPTOR//CHOLESTASIS 10277
9757 1                   URSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLIC ACID//BILE ACIDS 1123

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 URSODEOXYCHOLIC ACID authKW 1128904 17% 22% 187
2 TAUROURSODEOXYCHOLIC ACID authKW 362866 3% 43% 31
3 BILE ACIDS authKW 310252 16% 6% 185
4 TAUROURSODEOXYCHOLATE authKW 191159 1% 47% 15
5 URSODEOXYCHOLATE authKW 169916 1% 42% 15
6 GLYCOCHENODEOXYCHOLIC ACID authKW 158188 1% 73% 8
7 CHOLESTASIS authKW 152953 10% 5% 110
8 PATOGENESE MOL address 124224 3% 16% 29
9 HS 1200 authKW 108757 0% 100% 4
10 GLYCOCHENODEOXYCHOLATE authKW 108753 1% 67% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Gastroenterology & Hepatology 15660 36% 0% 402
2 Medicine, Research & Experimental 338 8% 0% 85
3 Oncology 325 11% 0% 121
4 Pharmacology & Pharmacy 316 12% 0% 137
5 Biochemistry & Molecular Biology 245 16% 0% 185
6 Toxicology 170 4% 0% 50
7 Transplantation 135 3% 0% 30
8 Biophysics 75 4% 0% 46
9 Medicine, General & Internal 64 5% 0% 59
10 Physiology 56 3% 0% 39

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PATOGENESE MOL 124224 3% 16% 29
2 PEDIAT LIVER 48363 1% 16% 11
3 PHYSIOPATHOL HEPAT 39543 0% 36% 4
4 IST SCI BIOMED S PAOLO INTERNAL MED 36251 0% 67% 2
5 MED PEDIAT CLIN MASS SPE OMETRY 36251 0% 67% 2
6 PEDIATLIVER TRANSPLANTAT PROGRAM 34954 0% 43% 3
7 A P HOSP 27189 0% 100% 1
8 AA VISHNEVSKY CENT MILIT CLIN HOSP 3 27189 0% 100% 1
9 ASHIKAGA PLANT 27189 0% 100% 1
10 BIOCHEM PHARMACAUT SCI 27189 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEPATOLOGY 12842 7% 1% 75
2 GASTROENTEROLOGY 4495 4% 0% 47
3 ITALIAN JOURNAL OF GASTROENTEROLOGY 3987 1% 2% 9
4 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 3623 3% 0% 29
5 JOURNAL OF HEPATOLOGY 3186 3% 0% 30
6 INTERNATIONAL HEPATOLOGY COMMUNICATIONS 3066 1% 2% 6
7 DIGESTIVE DISEASES AND SCIENCES 2138 3% 0% 32
8 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 1953 1% 1% 14
9 ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 1824 1% 1% 8
10 HEPATOLOGY RESEARCH 1704 1% 0% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 URSODEOXYCHOLIC ACID 1128904 17% 22% 187 Search URSODEOXYCHOLIC+ACID Search URSODEOXYCHOLIC+ACID
2 TAUROURSODEOXYCHOLIC ACID 362866 3% 43% 31 Search TAUROURSODEOXYCHOLIC+ACID Search TAUROURSODEOXYCHOLIC+ACID
3 BILE ACIDS 310252 16% 6% 185 Search BILE+ACIDS Search BILE+ACIDS
4 TAUROURSODEOXYCHOLATE 191159 1% 47% 15 Search TAUROURSODEOXYCHOLATE Search TAUROURSODEOXYCHOLATE
5 URSODEOXYCHOLATE 169916 1% 42% 15 Search URSODEOXYCHOLATE Search URSODEOXYCHOLATE
6 GLYCOCHENODEOXYCHOLIC ACID 158188 1% 73% 8 Search GLYCOCHENODEOXYCHOLIC+ACID Search GLYCOCHENODEOXYCHOLIC+ACID
7 CHOLESTASIS 152953 10% 5% 110 Search CHOLESTASIS Search CHOLESTASIS
8 HS 1200 108757 0% 100% 4 Search HS+1200 Search HS+1200
9 GLYCOCHENODEOXYCHOLATE 108753 1% 67% 6 Search GLYCOCHENODEOXYCHOLATE Search GLYCOCHENODEOXYCHOLATE
10 CHENODEOXYCHOLIC ACID 85350 2% 13% 25 Search CHENODEOXYCHOLIC+ACID Search CHENODEOXYCHOLIC+ACID

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ROMA, MG , TOLEDO, FD , BOAGLIO, AC , BASIGLIO, CL , CROCENZI, FA , POZZI, EJS , (2011) URSODEOXYCHOLIC ACID IN CHOLESTASIS: LINKING ACTION MECHANISMS TO THERAPEUTIC APPLICATIONS.CLINICAL SCIENCE. VOL. 121. ISSUE 11-12. P. 523-544 97 47% 36
2 PEREZ, MJ , BRIZ, O , (2009) BILE-ACID-INDUCED CELL INJURY AND PROTECTION.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 15. ISSUE 14. P. 1677 -1689 61 54% 159
3 BARRASA, JI , OLMO, N , LIZARBE, MA , TURNAY, J , (2013) BILE ACIDS IN THE COLON, FROM HEALTHY TO CYTOTOXIC MOLECULES.TOXICOLOGY IN VITRO. VOL. 27. ISSUE 2. P. 964 -977 60 43% 28
4 STIEHL, A , BENZ, C , SAUER, P , (1999) MECHANISM OF HEPATOPROTECTIVE ACTION OF BILE SALTS IN LIVER DISEASE.GASTROENTEROLOGY CLINICS OF NORTH AMERICA. VOL. 28. ISSUE 1. P. 195 -+ 63 67% 18
5 AMARAL, JD , VIANA, RJS , RAMALHO, RM , STEER, CJ , RODRIGUES, CMP , (2009) BILE ACIDS: REGULATION OF APOPTOSIS BY URSODEOXYCHOLIC ACID.JOURNAL OF LIPID RESEARCH. VOL. 50. ISSUE 9. P. 1721-1734 57 43% 81
6 BEUERS, U , (2006) DRUG INSIGHT: MECHANISMS AND SITES OF ACTION OF URSODEOXYCHOLIC ACID IN CHOLESTASIS.NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY. VOL. 3. ISSUE 6. P. 318-328 44 57% 140
7 KIM, ND , IM, E , YOO, YH , CHOI, YH , (2006) MODULATION OF THE CELL CYCLE AND INDUCTION OF APOPTOSIS IN HUMAN CANCER CELLS BY SYNTHETIC BILE ACIDS.CURRENT CANCER DRUG TARGETS. VOL. 6. ISSUE 8. P. 681 -689 57 52% 22
8 PALMEIRA, CM , ROLO, AP , (2004) MITOCHONDRIALLY-MEDIATED TOXICITY OF BILE ACIDS.TOXICOLOGY. VOL. 203. ISSUE 1-3. P. 1-15 46 60% 89
9 TRAUNER, M , GRAZIADEI, IW , (1999) REVIEW ARTICLE: MECHANISMS OF ACTION AND THERAPEUTIC APPLICATIONS OF URSODEOXYCHOLIC ACID IN CHRONIC LIVER DISEASES.ALIMENTARY PHARMACOLOGY & THERAPEUTICS. VOL. 13. ISSUE 8. P. 979 -995 71 45% 82
10 KASS, GEN , PRICE, SC , (2008) ROLE OF MITOCHONDRIA IN DRUG-INDUCED CHOLESTATIC INJURY.CLINICS IN LIVER DISEASE. VOL. 12. ISSUE 1. P. 27-+ 67 40% 8

Classes with closest relation at Level 1


Rank Class id link
1 5778 BILE ACIDS//SULFATED BILE ACID//TAURINE CONJUGATE
2 23258 7 ALPHA DEHYDROXYLATION//7 ALPHA HYDROXYSTEROID DEHYDROGENASE//CLOSTRIDIUM SCINDENS
3 3044 ORGANIC ANIONS//CANALICULAR MEMBRANE//BILITRANSLOCASE
4 5462 FARNESOID X RECEPTOR//FXR//TGR5
5 1756 PRIMARY BILIARY CIRRHOSIS//ANTIMITOCHONDRIAL ANTIBODIES//RHEUMATOL ALLERGY CLIN IMMUNOL
6 9589 OBSTRUCTIVE JAUNDICE//PREOPERATIVE BILIARY DRAINAGE//BILE DUCT LIGATION
7 9665 GALLSTONE RECURRENCE//GALLBLADDER CALCULI//GALLBLADDER INTERVENTIONAL PROCEDURE
8 18131 CHOLANGIOCYTES//INTRAHEPATIC BILIARY EPITHELIUM//SCOTT WHITE DIGEST DIS
9 9748 INTRAHEPATIC CHOLESTASIS OF PREGNANCY//PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS//ABCB11
10 16617 BILE ACID MALABSORPTION//SEHCAT//ASBT

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