Class information for:
Level 1: 7 ALPHA DEHYDROXYLATION//7 ALPHA HYDROXYSTEROID DEHYDROGENASE//CLOSTRIDIUM SCINDENS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23258 352 29.1 43%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
212 3       GASTROENTEROLOGY & HEPATOLOGY//LAPAROSCOPIC CHOLECYSTECTOMY//PRIMARY BILIARY CIRRHOSIS 51420
1019 2             BILE ACIDS//FARNESOID X RECEPTOR//CHOLESTASIS 10277
23258 1                   7 ALPHA DEHYDROXYLATION//7 ALPHA HYDROXYSTEROID DEHYDROGENASE//CLOSTRIDIUM SCINDENS 352

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 7 ALPHA DEHYDROXYLATION authKW 814455 4% 72% 13
2 7 ALPHA HYDROXYSTEROID DEHYDROGENASE authKW 433738 1% 100% 5
3 CLOSTRIDIUM SCINDENS authKW 361446 1% 83% 5
4 BILE ACID ESTER authKW 260243 1% 100% 3
5 12 ALPHA HYDROXYSTEROID DEHYDROGENASE authKW 173495 1% 100% 2
6 7 ALPHA DEHYDROXYLASE authKW 173495 1% 100% 2
7 BILE ACID CONVERSION authKW 173495 1% 100% 2
8 SECONDARY BILE ACIDS authKW 164355 2% 32% 6
9 CLOSTRIDIUM HIRANONIS authKW 115662 1% 67% 2
10 GRP PROBIOT FONCT DIGEST address 115662 1% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Microbiology 1696 30% 0% 104
2 Biotechnology & Applied Microbiology 968 23% 0% 81
3 Biochemistry & Molecular Biology 553 35% 0% 123
4 Endocrinology & Metabolism 211 11% 0% 37
5 Biophysics 72 6% 0% 22
6 Pharmacology & Pharmacy 32 8% 0% 29
7 Chemistry, Medicinal 22 3% 0% 11
8 Gastroenterology & Hepatology 20 3% 0% 11
9 Nutrition & Dietetics 19 3% 0% 9
10 Medical Laboratory Technology 17 1% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRP PROBIOT FONCT DIGEST 115662 1% 67% 2
2 ARC MICROBIOME 86748 0% 100% 1
3 DEUT ZENTRUM INFEKT FOR DZF 86748 0% 100% 1
4 MED INSELSPITAL 86748 0% 100% 1
5 MICROBIOL MARINE ER 223 86748 0% 100% 1
6 REFERENCE MALAD INFLAMMATOI VOIES BIL 86748 0% 100% 1
7 STRATEG INFORMAT UNIV 86748 0% 100% 1
8 UNIV KLIN VISZERALE CHIRURG 86748 0% 100% 1
9 VET MED YUSONG KU 86748 0% 100% 1
10 DRUG EXPLORAT LIVER DIGEST METAB DIS 43373 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF LIPID RESEARCH 10428 9% 0% 32
2 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4643 6% 0% 22
3 STEROIDS 3365 4% 0% 13
4 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 3143 9% 0% 33
5 JOURNAL OF FERMENTATION TECHNOLOGY 1699 1% 0% 4
6 EUROPEAN JOURNAL OF APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 1578 1% 1% 3
7 CURRENT MICROBIOLOGY 1204 3% 0% 9
8 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 956 2% 0% 7
9 BIOCHIMICA ET BIOPHYSICA ACTA 852 5% 0% 17
10 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 850 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 7 ALPHA DEHYDROXYLATION 814455 4% 72% 13 Search 7+ALPHA+DEHYDROXYLATION Search 7+ALPHA+DEHYDROXYLATION
2 7 ALPHA HYDROXYSTEROID DEHYDROGENASE 433738 1% 100% 5 Search 7+ALPHA+HYDROXYSTEROID+DEHYDROGENASE Search 7+ALPHA+HYDROXYSTEROID+DEHYDROGENASE
3 CLOSTRIDIUM SCINDENS 361446 1% 83% 5 Search CLOSTRIDIUM+SCINDENS Search CLOSTRIDIUM+SCINDENS
4 BILE ACID ESTER 260243 1% 100% 3 Search BILE+ACID+ESTER Search BILE+ACID+ESTER
5 12 ALPHA HYDROXYSTEROID DEHYDROGENASE 173495 1% 100% 2 Search 12+ALPHA+HYDROXYSTEROID+DEHYDROGENASE Search 12+ALPHA+HYDROXYSTEROID+DEHYDROGENASE
6 7 ALPHA DEHYDROXYLASE 173495 1% 100% 2 Search 7+ALPHA+DEHYDROXYLASE Search 7+ALPHA+DEHYDROXYLASE
7 BILE ACID CONVERSION 173495 1% 100% 2 Search BILE+ACID+CONVERSION Search BILE+ACID+CONVERSION
8 SECONDARY BILE ACIDS 164355 2% 32% 6 Search SECONDARY+BILE+ACIDS Search SECONDARY+BILE+ACIDS
9 CLOSTRIDIUM HIRANONIS 115662 1% 67% 2 Search CLOSTRIDIUM+HIRANONIS Search CLOSTRIDIUM+HIRANONIS
10 1 2 DIMETHYLHYDROAZINE DMH 86748 0% 100% 1 Search 1+2+DIMETHYLHYDROAZINE+DMH Search 1+2+DIMETHYLHYDROAZINE+DMH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RIDLON, JM , KANG, DJ , HYLEMON, PB , (2006) BILE SALT BIOTRANSFORMATIONS BY HUMAN INTESTINAL BACTERIA.JOURNAL OF LIPID RESEARCH. VOL. 47. ISSUE 2. P. 241-259 57 44% 460
2 BORTOLINI, O , MEDICI, A , POLI, S , (1997) BIOTRANSFORMATIONS ON STEROID NUCLEUS OF BILE ACIDS.STEROIDS. VOL. 62. ISSUE 8-9. P. 564 -577 49 80% 53
3 EGGERT, T , BAKONYI, D , HUMMEL, W , (2014) ENZYMATIC ROUTES FOR THE SYNTHESIS OF URSODEOXYCHOLIC ACID.JOURNAL OF BIOTECHNOLOGY. VOL. 191. ISSUE . P. 11 -21 31 61% 5
4 PRABHA, V , OHRI, M , (2006) REVIEW: BACTERIAL TRANSFORMATIONS OF BILE ACIDS.WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY. VOL. 22. ISSUE 2. P. 191-196 34 68% 8
5 ZHENG, MM , WANG, RF , LI, CX , XU, JH , (2015) TWO-STEP ENZYMATIC SYNTHESIS OF URSODEOXYCHOLIC ACID WITH A NEW 7 BETA-HYDROXYSTEROID DEHYDROGENASE FROM RUMINOCOCCUS TORQUES.PROCESS BIOCHEMISTRY. VOL. 50. ISSUE 4. P. 598 -604 23 79% 1
6 FERRANDI, EE , BERTOLESI, GM , POLENTINI, F , NEGRI, A , RIVA, S , MONTI, D , (2012) IN SEARCH OF SUSTAINABLE CHEMICAL PROCESSES: CLONING, RECOMBINANT EXPRESSION, AND FUNCTIONAL CHARACTERIZATION OF THE 7 ALPHA- AND 7 BETA-HYDROXYSTEROID DEHYDROGENASES FROM CLOSTRIDIUM ABSONUM.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 95. ISSUE 5. P. 1221-1233 20 69% 7
7 RIDLON, JM , KANG, DJ , HYLEMON, PB , (2010) ISOLATION AND CHARACTERIZATION OF A BILE ACID INDUCIBLE 7 ALPHA-DEHYDROXYLATING OPERON IN CLOSTRIDIUM HYLEMONAE TN271.ANAEROBE. VOL. 16. ISSUE 2. P. 137-146 19 70% 20
8 GIOVANNINI, PP , GRANDINI, A , PERRONE, D , PEDRINI, P , FANTIN, G , FOGAGNOLO, M , (2008) 7 ALPHA- AND 12 ALPHA-HYDROXYSTEROID DEHYDROGENASES FROM ACINETOBACTER CALCOACETICUS LWOFFII: A NEW INTEGRATED CHEMO-ENZYMATIC ROUTE TO URSODEOXYCHOLIC ACID.STEROIDS. VOL. 73. ISSUE 14. P. 1385 -1390 14 78% 6
9 NARUSHIMA, S , ITOH, K , MIYAMOTO, Y , PARK, SH , NAGATA, K , KURUMA, K , UCHIDA, K , (2006) DEOXYCHOLIC ACID FORMATION IN GNOTOBIOTIC MICE ASSOCIATED WITH HUMAN INTESTINAL BACTERIA.LIPIDS. VOL. 41. ISSUE 9. P. 835-843 19 56% 23
10 MACDONALD, IA , BOKKENHEUSER, VD , WINTER, J , MCLERNON, AM , MOSBACH, EH , (1983) DEGRADATION OF STEROIDS IN THE HUMAN GUT.JOURNAL OF LIPID RESEARCH. VOL. 24. ISSUE 6. P. 675-700 30 70% 209

Classes with closest relation at Level 1


Rank Class id link
1 5778 BILE ACIDS//SULFATED BILE ACID//TAURINE CONJUGATE
2 7955 ANDROST 4 ENE 3 17 DIONE//3 KETOSTEROID DELTA1 DEHYDROGENASE//ARTHROBACTER SIMPLEX
3 9757 URSODEOXYCHOLIC ACID//TAUROURSODEOXYCHOLIC ACID//BILE ACIDS
4 25395 MICROFLORA ASSOCIATED CHARACTERISTICS//BETA ASPARTYLGLYCINE//MED MICROBIAL ECOL
5 9665 GALLSTONE RECURRENCE//GALLBLADDER CALCULI//GALLBLADDER INTERVENTIONAL PROCEDURE
6 35824 INO 2628 CZ//EFFICIENCY OF ENTEROHEPATIC CIRCULATION//MNP001
7 27737 NADH OXIDASE//H2O FORMING NADH OXIDASE//NADH PEROXIDASE
8 2528 PROBIOTICS//BILE SALT HYDROLASE//BILE TOLERANCE
9 14214 NADH REGENERATION//COFACTOR REGENERATION//BIOMIMETIC COENZYME
10 5462 FARNESOID X RECEPTOR//FXR//TGR5

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