Class information for:
Level 1: AHSP//RECOMBINANT MUTANT HEMOGLOBIN//5 5 DITHIOBIS2 NITROBENZOATE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8467 1250 36.0 48%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
519 3       BLOOD SUBSTITUTES//NEUROGLOBIN//HEMOGLOBIN 20769
1479 2             NEUROGLOBIN//CYTOGLOBIN//HEMOGLOBIN 7662
8467 1                   AHSP//RECOMBINANT MUTANT HEMOGLOBIN//5 5 DITHIOBIS2 NITROBENZOATE 1250

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AHSP authKW 187893 1% 77% 10
2 RECOMBINANT MUTANT HEMOGLOBIN authKW 122133 0% 100% 5
3 5 5 DITHIOBIS2 NITROBENZOATE authKW 101776 0% 83% 5
4 RECOMBINANT HEMOGLOBIN authKW 94207 1% 43% 9
5 HUMAN HEMOGLOBIN authKW 82524 1% 24% 14
6 ALPHA HEMOGLOBIN STABILIZING PROTEIN AHSP authKW 78164 0% 80% 4
7 HYBRID HEMOGLOBIN authKW 78164 0% 80% 4
8 MUTANT HEMOGLOBIN authKW 78164 0% 80% 4
9 HEMOGLOBIN authKW 63499 10% 2% 120
10 LOW OXYGEN AFFINITY authKW 58617 0% 40% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 11702 77% 0% 967
2 Biophysics 4946 23% 0% 291
3 Biochemical Research Methods 535 8% 0% 97
4 Hematology 166 4% 0% 54
5 Biology 90 3% 0% 39
6 Chemistry, Physical 90 9% 0% 112
7 Crystallography 38 2% 0% 27
8 Mathematical & Computational Biology 29 1% 0% 15
9 Physics, Atomic, Molecular & Chemical 3 2% 0% 26
10 Education, Scientific Disciplines 3 0% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HALL ATWATER S 203 36637 0% 50% 3
2 U779 28410 1% 15% 8
3 AGING MOL BIOL 24427 0% 100% 1
4 ANAT STRUCT BIOPHYS 24427 0% 100% 1
5 BIOCHEM SCI EXPTL MED 24427 0% 100% 1
6 BIOL TIMINGGEN CLIN BIOMATH TECH 24427 0% 100% 1
7 BIOMATH TECHNOLNSF BIOL TIMING 24427 0% 100% 1
8 CAD IL 24427 0% 100% 1
9 CHEM CNR CHEM RECEPTORS 24427 0% 100% 1
10 CHEM REG SOPHISTICATED RUMENTAT 24427 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHYSICAL CHEMISTRY 25827 5% 2% 67
2 BIOCHEMISTRY 18673 16% 0% 202
3 JOURNAL OF MOLECULAR BIOLOGY 8407 7% 0% 90
4 HEMOGLOBIN 4309 2% 1% 20
5 INORGANIC BIOCHEMISTRY 3052 0% 13% 1
6 JOURNAL OF PROTEIN CHEMISTRY 2739 1% 1% 13
7 METHODS IN ENZYMOLOGY 2583 3% 0% 42
8 JOURNAL OF BIOLOGICAL CHEMISTRY 2498 10% 0% 128
9 BIOPHYSICAL JOURNAL 2255 3% 0% 43
10 PROTEIN SCIENCE 1524 2% 0% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AHSP 187893 1% 77% 10 Search AHSP Search AHSP
2 RECOMBINANT MUTANT HEMOGLOBIN 122133 0% 100% 5 Search RECOMBINANT+MUTANT+HEMOGLOBIN Search RECOMBINANT+MUTANT+HEMOGLOBIN
3 5 5 DITHIOBIS2 NITROBENZOATE 101776 0% 83% 5 Search 5+5+DITHIOBIS2+NITROBENZOATE Search 5+5+DITHIOBIS2+NITROBENZOATE
4 RECOMBINANT HEMOGLOBIN 94207 1% 43% 9 Search RECOMBINANT+HEMOGLOBIN Search RECOMBINANT+HEMOGLOBIN
5 HUMAN HEMOGLOBIN 82524 1% 24% 14 Search HUMAN+HEMOGLOBIN Search HUMAN+HEMOGLOBIN
6 ALPHA HEMOGLOBIN STABILIZING PROTEIN AHSP 78164 0% 80% 4 Search ALPHA+HEMOGLOBIN+STABILIZING+PROTEIN+AHSP Search ALPHA+HEMOGLOBIN+STABILIZING+PROTEIN+AHSP
7 HYBRID HEMOGLOBIN 78164 0% 80% 4 Search HYBRID+HEMOGLOBIN Search HYBRID+HEMOGLOBIN
8 MUTANT HEMOGLOBIN 78164 0% 80% 4 Search MUTANT+HEMOGLOBIN Search MUTANT+HEMOGLOBIN
9 HEMOGLOBIN 63499 10% 2% 120 Search HEMOGLOBIN Search HEMOGLOBIN
10 LOW OXYGEN AFFINITY 58617 0% 40% 6 Search LOW+OXYGEN+AFFINITY Search LOW+OXYGEN+AFFINITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YUAN, Y , TAM, MF , SIMPLACEANU, V , HO, C , (2015) NEW LOOK AT HEMOGLOBIN ALLOSTERY.CHEMICAL REVIEWS. VOL. 115. ISSUE 4. P. 1702 -1724 99 66% 17
2 VENKATESH, B , MANOHARAN, PT , RIFKIND, JM , (1998) METAL ION RECONSTITUTED HYBRID HEMOGLOBINS.PROGRESS IN INORGANIC CHEMISTRY, VOL 47. VOL. 47. ISSUE . P. 563 -684 143 73% 6
3 BELLELLI, A , (2010) HEMOGLOBIN AND COOPERATIVITY: EXPERIMENTS AND THEORIES.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 11. ISSUE 1. P. 2-36 74 90% 14
4 BELLELLI, A , BRUNORI, M , MIELE, AE , PANETTA, G , VALLONE, B , (2006) THE ALLOSTERIC PROPERTIES OF HEMOGLOBIN: INSIGHTS FROM NATURAL AND SITE DIRECTED MUTANTS.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 7. ISSUE 1. P. 17-45 90 67% 25
5 ACKERS, GK , (1998) DECIPHERING THE MOLECULAR CODE OF HEMOGLOBIN ALLOSTERY.ADVANCES IN PROTEIN CHEMISTRY, VOL 51. VOL. 51. ISSUE . P. 185 -253 80 81% 83
6 SAMUNI, U , ROCHE, CJ , DANTSKER, D , JUSZCZAK, LJ , FRIEDMAN, JM , (2006) MODULATION OF REACTIVITY AND CONFORMATION WITHIN THE T-QUATERNARY STATE OF HUMAN HEMOGLOBIN: THE COMBINED USE OF MUTAGENESIS AND SOL-GEL ENCAPSULATION.BIOCHEMISTRY. VOL. 45. ISSUE 9. P. 2820-2835 67 66% 42
7 YUAN, Y , SIMPLACEANU, V , HO, NT , HO, C , (2010) AN INVESTIGATION OF THE DISTAL HISTIDYL HYDROGEN BONDS IN OXYHEMOGLOBIN: EFFECTS OF TEMPERATURE, PH, AND INOSITOL HEXAPHOSPHATE.BIOCHEMISTRY. VOL. 49. ISSUE 50. P. 10606-10615 41 95% 7
8 MARDEN, MC , KIGER, L , POYART, C , EDELSTEIN, SJ , (1998) IDENTIFYING THE CONFORMATIONAL STATE OF BI-LIGANDED HAEMOGLOBIN.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 54. ISSUE 12. P. 1365 -1384 63 90% 4
9 HO, C , (1992) PROTON NUCLEAR-MAGNETIC-RESONANCE STUDIES ON HEMOGLOBIN - COOPERATIVE INTERACTIONS AND PARTIALLY LIGATED INTERMEDIATES.ADVANCES IN PROTEIN CHEMISTRY. VOL. 43. ISSUE . P. 153-312 80 79% 83
10 KNEIPP, J , BALAKRISHNAN, G , CHEN, RP , SHEN, TJ , SAHU, SC , HO, NT , GIOVANNELLI, JL , SIMPLACEANU, V , HO, C , SPIRO, TG , (2006) DYNAMICS OF ALLOSTERY IN HEMOGLOBIN: ROLES OF THE PENULTIMATE TYROSINE H BONDS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 356. ISSUE 2. P. 335-353 52 80% 19

Classes with closest relation at Level 1


Rank Class id link
1 9817 ROOT EFFECT//BOHR EFFECT//OXYGEN AFFINITY
2 2055 MYOGLOBIN//WM KECK COMPUTAT BIOL//LIGAND MIGRATION
3 13096 ANTISICKLING ACTIVITY//ANTISICKLING AGENTS THERAPEUTIC USE//ANTISICKLING
4 31038 FERRI AND FERROCYANIDE//ACQUIRED DNA BINDING ACTIVITY//BIOLOGY B022
5 5340 HEMOGLOBIN//HEMOGLOBIN VARIANTS//HEMOGLOBIN HB VARIANT
6 12706 EXTRACELLULAR HEMOGLOBIN//GLOSSOSCOLEX PAULISTUS//ERYTHROCRUORIN
7 18157 GRP BIOPHYS MOL//UV RESONANCE RAMAN SPECTROSCOPY//ULTRAVIOLET RESONANCE RAMAN
8 2052 BLOOD SUBSTITUTES//HEMOGLOBIN BASED OXYGEN CARRIER//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
9 20249 RSR13//OXYHEMOGLOBIN DISSOCIATION CURVE//ALLOSTERIC MODIFIER
10 26346 1 4 BIS2 2 6 6 TETRAMETHYL 1 OXYL 4 PIPERIDYLBUTANE//BIOORGAN PHYS//CLASSICAL FERROMAGNET

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