Class information for:
Level 1: BLOOD SUBSTITUTES//HEMOGLOBIN BASED OXYGEN CARRIER//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2052 2372 32.3 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
519 3       BLOOD SUBSTITUTES//NEUROGLOBIN//HEMOGLOBIN 20769
2593 2             BLOOD SUBSTITUTES//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY//HEMOGLOBIN BASED OXYGEN CARRIER 3632
2052 1                   BLOOD SUBSTITUTES//HEMOGLOBIN BASED OXYGEN CARRIER//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 2372

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD SUBSTITUTES authKW 3495057 15% 74% 367
2 HEMOGLOBIN BASED OXYGEN CARRIER authKW 1121076 4% 82% 106
3 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY journal 929897 10% 30% 240
4 ARTIFICIAL OXYGEN CARRIER authKW 585104 2% 78% 58
5 LIPOSOME ENCAPSULATED HEMOGLOBIN authKW 400482 1% 94% 33
6 BIOMATERIALS ARTIFICIAL CELLS AND IMMOBILIZATION BIOTECHNOLOGY journal 370391 4% 34% 85
7 DIASPIRIN CROSS LINKED HEMOGLOBIN authKW 362006 1% 94% 30
8 POLYHEMOGLOBIN authKW 259571 1% 92% 22
9 HBOC 201 authKW 258012 1% 95% 21
10 OXYGEN CARRIER authKW 244887 4% 21% 91

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Materials Science, Biomaterials 29713 19% 1% 441
2 Engineering, Biomedical 24350 26% 0% 607
3 Critical Care Medicine 4668 9% 0% 212
4 Biotechnology & Applied Microbiology 3271 17% 0% 398
5 Anesthesiology 1680 5% 0% 127
6 Hematology 1338 8% 0% 189
7 Peripheral Vascular Diseases 981 7% 0% 158
8 Transplantation 902 4% 0% 105
9 Biochemistry & Molecular Biology 562 17% 0% 402
10 Physiology 478 6% 0% 139

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMATOL PHYSIOL 107239 1% 42% 20
2 ARTIFICIAL CELLS ORGANS 103016 1% 24% 33
3 BIOCHEM VASC BIOL 101954 1% 29% 27
4 ORTHOPED PLAST HAND SURG 57919 0% 75% 6
5 MARTIN LUTHER KING JR DREW MED 53629 0% 83% 5
6 HEMOGLOBIN THER EUT 45967 0% 71% 5
7 ION CHIRICUTA CANC 41187 0% 80% 4
8 FORMULAT TOXICOL 38614 0% 100% 3
9 KOFFOLT S 425 38614 0% 100% 3
10 ADV SCI ENGN 34010 3% 3% 82

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 929897 10% 30% 240
2 BIOMATERIALS ARTIFICIAL CELLS AND IMMOBILIZATION BIOTECHNOLOGY 370391 4% 34% 85
3 BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS 167861 2% 23% 57
4 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 146791 2% 31% 37
5 ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY 36642 2% 8% 37
6 ARTIFICIAL ORGANS 12622 3% 2% 66
7 SHOCK 5980 2% 1% 43
8 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 4822 2% 1% 39
9 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 4285 3% 1% 65
10 BIOCONJUGATE CHEMISTRY 3475 2% 1% 37

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BLOOD SUBSTITUTES 3495057 15% 74% 367 Search BLOOD+SUBSTITUTES Search BLOOD+SUBSTITUTES
2 HEMOGLOBIN BASED OXYGEN CARRIER 1121076 4% 82% 106 Search HEMOGLOBIN+BASED+OXYGEN+CARRIER Search HEMOGLOBIN+BASED+OXYGEN+CARRIER
3 ARTIFICIAL OXYGEN CARRIER 585104 2% 78% 58 Search ARTIFICIAL+OXYGEN+CARRIER Search ARTIFICIAL+OXYGEN+CARRIER
4 LIPOSOME ENCAPSULATED HEMOGLOBIN 400482 1% 94% 33 Search LIPOSOME+ENCAPSULATED+HEMOGLOBIN Search LIPOSOME+ENCAPSULATED+HEMOGLOBIN
5 DIASPIRIN CROSS LINKED HEMOGLOBIN 362006 1% 94% 30 Search DIASPIRIN+CROSS+LINKED+HEMOGLOBIN Search DIASPIRIN+CROSS+LINKED+HEMOGLOBIN
6 POLYHEMOGLOBIN 259571 1% 92% 22 Search POLYHEMOGLOBIN Search POLYHEMOGLOBIN
7 HBOC 201 258012 1% 95% 21 Search HBOC+201 Search HBOC+201
8 OXYGEN CARRIER 244887 4% 21% 91 Search OXYGEN+CARRIER Search OXYGEN+CARRIER
9 HEMOGLOBIN SOLUTIONS 239149 1% 77% 24 Search HEMOGLOBIN+SOLUTIONS Search HEMOGLOBIN+SOLUTIONS
10 FUNCTIONAL CAPILLARY DENSITY 225412 1% 52% 34 Search FUNCTIONAL+CAPILLARY+DENSITY Search FUNCTIONAL+CAPILLARY+DENSITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RIESS, JG , (2001) OXYGEN CARRIERS ("BLOOD SUBSTITUTES") - RAISON D'ETRE, CHEMISTRY, AND SOME PHYSIOLOGY.CHEMICAL REVIEWS. VOL. 101. ISSUE 9. P. 2797 -2919 551 43% 417
2 WINSLOW, RM , (2000) ALPHA ALPHA-CROSSLINKED HEMOGLOBIN: WAS FAILURE PREDICTED BY PRECLINICAL TESTING?.VOX SANGUINIS. VOL. 79. ISSUE 1. P. 1 -20 105 86% 62
3 SAKAI, H , SOU, K , TSUCHIDA, E , (2009) HEMOGLOBIN-VESICLES AS AN ARTIFICIAL OXYGEN CARRIER.METHODS IN ENZYMOLOGY LIPOSOMES, PT G. VOL. 465. ISSUE . P. 363-384 78 85% 8
4 TSUCHIDA, E , SOU, K , NAKAGAWA, A , SAKAI, H , KOMATSU, T , KOBAYASHI, K , (2009) ARTIFICIAL OXYGEN CARRIERS, HEMOGLOBIN VESICLES AND ALBUMIN-HEMES, BASED ON BIOCONJUGATE CHEMISTRY.BIOCONJUGATE CHEMISTRY. VOL. 20. ISSUE 8. P. 1419-1440 92 61% 66
5 CRETEUR, J , VINCENT, JL , (2003) HEMOGLOBIN SOLUTIONS.CRITICAL CARE MEDICINE. VOL. 31. ISSUE 12. P. S698-S707 87 85% 23
6 BUEHLER, PW , ALAYASH, AI , (2004) TOXICITIES OF HEMOGLOBIN SOLUTIONS: IN SEARCH OF IN-VITRO AND IN-VIVO MODEL SYSTEMS.TRANSFUSION. VOL. 44. ISSUE 10. P. 1516-1530 91 75% 55
7 KIM, JH , LEE, KY , (2009) CURRENT STATUS AND FUTURE OF ARTIFICIAL BLOOD - FOCUSING ON RED BLOOD CELL SUBSTITUTES.JOURNAL OF THE KOREAN MEDICAL ASSOCIATION. VOL. 52. ISSUE 2. P. 168 -181 66 90% 0
8 CRETEUR, J , VINCENT, JL , (2009) POTENTIAL USES OF HEMOGLOBIN-BASED OXYGEN CARRIERS IN CRITICAL CARE MEDICINE.CRITICAL CARE CLINICS. VOL. 25. ISSUE 2. P. 311-+ 69 83% 11
9 CABRALES, P , INTAGLIETTA, M , (2013) BLOOD SUBSTITUTES: EVOLUTION FROM NONCARRYING TO OXYGEN- AND GAS-CARRYING FLUIDS.ASAIO JOURNAL. VOL. 59. ISSUE 4. P. 337-354 102 48% 15
10 LI, TH , JING, XB , HUANG, YB , (2011) POLYMER/HEMOGLOBIN ASSEMBLIES: BIODEGRADABLE OXYGEN CARRIERS FOR ARTIFICIAL RED BLOOD CELLS.MACROMOLECULAR BIOSCIENCE. VOL. 11. ISSUE 7. P. 865 -874 71 73% 10

Classes with closest relation at Level 1


Rank Class id link
1 12550 PERFLUOROCHEMICAL EMULSION//BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS//FLUOSOL
2 18717 FERRYLMYOGLOBIN//PERFERRYLMYOGLOBIN//FERRYLHEMOGLOBIN
3 8467 AHSP//RECOMBINANT MUTANT HEMOGLOBIN//5 5 DITHIOBIS2 NITROBENZOATE
4 11959 OXYGEN DEPENDENT QUENCHING//OXYGEN TRANSPORT//PHOSPHORESCENCE QUENCHING MICROSCOPY
5 20249 RSR13//OXYHEMOGLOBIN DISSOCIATION CURVE//ALLOSTERIC MODIFIER
6 7655 NITRITE//DIETARY NITRATE//S NITROSOHEMOGLOBIN
7 13096 ANTISICKLING ACTIVITY//ANTISICKLING AGENTS THERAPEUTIC USE//ANTISICKLING
8 21760 COBALTPORPHYRIN//POLYMER CHEM SHINJUKU KU//ALUMINUM PACKING
9 5629 HYPERTONIC SALINE//SMALL VOLUME RESUSCITATION//HYPERTONIC SOLUTIONS
10 34353 2 STEP COUPLING PROCEDURE//5929 KAMISHINEI CHO//ANTI GABA

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