Class information for:
Level 1: GRAPEFRUIT JUICE//HERB DRUG INTERACTION//ST JOHNS WORT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6576 1468 44.9 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
2 3       INTEGRATIVE & COMPLEMENTARY MEDICINE//CHEMISTRY, MEDICINAL//ESSENTIAL OIL 193989
1733 2             ST JOHNS WORT//GINKGO BILOBA//HYPERICUM PERFORATUM 6555
6576 1                   GRAPEFRUIT JUICE//HERB DRUG INTERACTION//ST JOHNS WORT 1468

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRAPEFRUIT JUICE authKW 1858888 10% 62% 144
2 HERB DRUG INTERACTION authKW 1061628 9% 38% 135
3 ST JOHNS WORT authKW 292703 6% 17% 81
4 BERGAMOTTIN authKW 261335 1% 74% 17
5 DRUG HERB INTERACTION authKW 160892 1% 37% 21
6 FURANOCOUMARINS authKW 150644 3% 16% 46
7 DRUG INTERACTIONS authKW 147541 12% 4% 171
8 GRAPEFRUIT authKW 131088 3% 17% 38
9 FOOD DRUG INTERACTION authKW 127407 2% 25% 25
10 6 7 DIHYDROXYBERGAMOTTIN authKW 124794 0% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 16187 61% 0% 889
2 Integrative & Complementary Medicine 7621 9% 0% 130
3 Chemistry, Medicinal 1821 11% 0% 162
4 Toxicology 569 7% 0% 97
5 Food Science & Technology 215 6% 0% 81
6 Medicine, General & Internal 147 6% 0% 93
7 Plant Sciences 88 5% 0% 74
8 Nutrition & Dietetics 86 3% 0% 39
9 Medical Laboratory Technology 73 1% 0% 21
10 Geriatrics & Gerontology 68 1% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THER EUT PROD DIRECTORATE 91779 1% 28% 16
2 CLIN NATUROPATHY 41598 0% 100% 2
3 COMPLEMENTARY ALTERNAT PROGRAM CARE INTEGRA 41598 0% 100% 2
4 EDUC COMPLEMENTARY INTEGRATED MED THE 41598 0% 100% 2
5 SACKLER PROGRAM PHARMACOL EXPT THER EUT 41598 0% 100% 2
6 NAT PROD STUDIES 38434 1% 13% 14
7 MARKETED BIOL BIOTECHNOL NAT HLTH PROD BUR 37436 0% 60% 3
8 BIOPHARMACEUT BIOTECHNOL 35084 1% 19% 9
9 MARKETED HLTH PROD DIRECTORATE 27727 0% 33% 4
10 HERBAL MED UNIT 26738 0% 43% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL PHARMACOLOGY & THERAPEUTICS 17937 5% 1% 71
2 BOLET?N LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS 17013 0% 27% 3
3 CURRENT DRUG METABOLISM 6826 1% 2% 19
4 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 6346 3% 1% 50
5 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 5381 3% 1% 43
6 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 5381 1% 1% 20
7 PHYTOTHERAPY RESEARCH 3649 2% 1% 31
8 JOURNAL OF CLINICAL PHARMACOLOGY 3634 2% 1% 31
9 JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES 3620 1% 2% 11
10 DRUG METABOLISM AND DISPOSITION 3537 2% 0% 36

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GRAPEFRUIT JUICE 1858888 10% 62% 144 Search GRAPEFRUIT+JUICE Search GRAPEFRUIT+JUICE
2 HERB DRUG INTERACTION 1061628 9% 38% 135 Search HERB+DRUG+INTERACTION Search HERB+DRUG+INTERACTION
3 ST JOHNS WORT 292703 6% 17% 81 Search ST+JOHNS+WORT Search ST+JOHNS+WORT
4 BERGAMOTTIN 261335 1% 74% 17 Search BERGAMOTTIN Search BERGAMOTTIN
5 DRUG HERB INTERACTION 160892 1% 37% 21 Search DRUG+HERB+INTERACTION Search DRUG+HERB+INTERACTION
6 FURANOCOUMARINS 150644 3% 16% 46 Search FURANOCOUMARINS Search FURANOCOUMARINS
7 DRUG INTERACTIONS 147541 12% 4% 171 Search DRUG+INTERACTIONS Search DRUG+INTERACTIONS
8 GRAPEFRUIT 131088 3% 17% 38 Search GRAPEFRUIT Search GRAPEFRUIT
9 FOOD DRUG INTERACTION 127407 2% 25% 25 Search FOOD+DRUG+INTERACTION Search FOOD+DRUG+INTERACTION
10 6 7 DIHYDROXYBERGAMOTTIN 124794 0% 100% 6 Search 6+7+DIHYDROXYBERGAMOTTIN Search 6+7+DIHYDROXYBERGAMOTTIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SHI, SJ , KLOTZ, U , (2012) DRUG INTERACTIONS WITH HERBAL MEDICINES.CLINICAL PHARMACOKINETICS. VOL. 51. ISSUE 2. P. 77-104 185 64% 41
2 HANLEY, MJ , CANCALON, P , WIDMER, WW , GREENBLATT, DJ , (2011) THE EFFECT OF GRAPEFRUIT JUICE ON DRUG DISPOSITION.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 7. ISSUE 3. P. 267 -286 146 78% 53
3 IZZO, AA , (2012) INTERACTIONS BETWEEN HERBS AND CONVENTIONAL DRUGS: OVERVIEW OF THE CLINICAL DATA.MEDICAL PRINCIPLES AND PRACTICE. VOL. 21. ISSUE 5. P. 404-428 138 79% 31
4 IZZO, AA , ERNST, E , (2009) INTERACTIONS BETWEEN HERBAL MEDICINES AND PRESCRIBED DRUGS AN UPDATED SYSTEMATIC REVIEW.DRUGS. VOL. 69. ISSUE 13. P. 1777 -1798 109 81% 223
5 MERTENS-TALCOTT, SU , ZADEZENSKY, I , DE CASTRO, WV , DERENDORF, H , BUTTERWECK, V , (2006) GRAPEFRUIT-DRUG INTERACTIONS: CAN INTERACTIONS WITH DRUGS BE AVOIDED?.JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 46. ISSUE 12. P. 1390-1416 136 77% 62
6 SEDEN, K , DICKINSON, L , KHOO, S , BACK, D , (2010) GRAPEFRUIT-DRUG INTERACTIONS.DRUGS. VOL. 70. ISSUE 18. P. 2373 -2407 120 67% 46
7 VIEIRA, MDT , HUANG, SM , (2012) BOTANICAL-DRUG INTERACTIONS: A SCIENTIFIC PERSPECTIVE.PLANTA MEDICA. VOL. 78. ISSUE 13. P. 1400 -1415 104 66% 21
8 HU, M , FAN, L , ZHOU, HH , TOMLINSON, B , (2012) THERANOSTICS MEETS TRADITIONAL CHINESE MEDICINE: RATIONAL PREDICTION OF DRUG-HERB INTERACTIONS.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 12. ISSUE 8. P. 815-830 106 68% 6
9 MENG, Q , LIU, KX , (2014) PHARMACOKINETIC INTERACTIONS BETWEEN HERBAL MEDICINES AND PRESCRIBED DRUGS: FOCUS ON DRUG METABOLIC ENZYMES AND TRANSPORTERS.CURRENT DRUG METABOLISM. VOL. 15. ISSUE 8. P. 791 -807 107 60% 11
10 GURLEY, BJ , FIFER, EK , GARDNER, Z , (2012) PHARMACOKINETIC HERB-DRUG INTERACTIONS (PART 2): DRUG INTERACTIONS INVOLVING POPULAR BOTANICAL DIETARY SUPPLEMENTS AND THEIR CLINICAL RELEVANCE.PLANTA MEDICA. VOL. 78. ISSUE 13. P. 1490-1514 154 43% 26

Classes with closest relation at Level 1


Rank Class id link
1 4852 6 BETA HYDROXYCORTISOL//COCKTAIL//CYP3A
2 6243 HYPERICUM PERFORATUM//HYPERFORIN//ST JOHNS WORT
3 21628 KAVA//PIPER METHYSTICUM//KAVALACTONES
4 346 COMPLEMENTARY AND ALTERNATIVE MEDICINE//COMPLEMENTARY MEDICINE//ALTERNATIVE MEDICINE
5 5391 GINKGO BILOBA//GINKGO BILOBA EXTRACT//BILOBALIDE
6 18922 COMPLEMENTARY AND ALTERNATIVE MEDICINE//HOLIST PEDIAT EDUC//CARE PROGRAM INTEGRAT HLTH HEALING
7 5456 OATP1B1//SLCO1B1//OATP
8 12922 DIETARY SUPPLEMENTS//MULTIVITAMINS//SUPPLEMENT COMPOSITION
9 22471 STERILE WATER INJECTIONS//STERILE WATER//SERV ACUPUNCTURE
10 3955 PREGNANE X RECEPTOR//PXR//CONSTITUTIVE ANDROSTANE RECEPTOR

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