Class information for:
Level 1: REMACEMIDE//LOSIGAMONE//DESGLYCINYL REMACEMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
34927 104 30.4 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
143 3       EPILEPSY//EPILEPSIA//EPILEPSY & BEHAVIOR 64226
230 2             ANTIEPILEPTIC DRUGS//LEVETIRACETAM//EPILEPSY 20331
34927 1                   REMACEMIDE//LOSIGAMONE//DESGLYCINYL REMACEMIDE 104

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REMACEMIDE authKW 5220541 26% 66% 27
2 LOSIGAMONE authKW 4136088 17% 78% 18
3 DESGLYCINYL REMACEMIDE authKW 1468059 5% 100% 5
4 REMACEMIDE HYDROCHLORIDE authKW 1027634 7% 50% 7
5 FPL 12495AA authKW 880835 3% 100% 3
6 IST SCI NEUROL NEUROCHIRURG address 440415 3% 50% 3
7 CARABERSAT authKW 391481 2% 67% 2
8 ACUTE STROKE UNITGARDINER address 293612 1% 100% 1
9 ANIMAL MODEL OF SEIZURES authKW 293612 1% 100% 1
10 AO 242 authKW 293612 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 674 47% 0% 49
2 Clinical Neurology 642 35% 0% 36
3 Neurosciences 216 28% 0% 29
4 Chemistry, Analytical 6 5% 0% 5
5 Behavioral Sciences 4 2% 0% 2
6 Biochemical Research Methods 3 3% 0% 3
7 Psychiatry 2 3% 0% 3
8 Peripheral Vascular Diseases 2 2% 0% 2
9 Chemistry, Medicinal 0 1% 0% 1
10 Toxicology 0 1% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IST SCI NEUROL NEUROCHIRURG 440415 3% 50% 3
2 ACUTE STROKE UNITGARDINER 293612 1% 100% 1
3 EPILEPSY THER EUT BRANCH 293612 1% 100% 1
4 INSERM 0244 CORTEX EPILEPSY 293612 1% 100% 1
5 IST SCI BIOCHIM BIOCHIM CLIN 73401 1% 25% 1
6 MINCEP 73401 1% 25% 1
7 PHARM NEUROL 73401 1% 25% 1
8 SINO GERMAN EPILEPSY 58721 1% 20% 1
9 FONDAZ SANTA LUCIA 45167 2% 8% 2
10 NANOTECHNOL DRUG 36700 1% 13% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPILEPSY RESEARCH 12829 13% 0% 13
2 SEIZURE 4811 1% 2% 1
3 SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 3019 5% 0% 5
4 POLISH JOURNAL OF PHARMACOLOGY 1778 2% 0% 2
5 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 1684 11% 0% 11
6 PHARMACOLOGICAL REPORTS 1471 3% 0% 3
7 JOURNAL OF EPILEPSY 738 1% 0% 1
8 AMINO ACIDS 737 3% 0% 3
9 DRUG METABOLISM AND DISPOSITION 621 4% 0% 4
10 EXPERT OPINION ON INVESTIGATIONAL DRUGS 544 2% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 REMACEMIDE 5220541 26% 66% 27 Search REMACEMIDE Search REMACEMIDE
2 LOSIGAMONE 4136088 17% 78% 18 Search LOSIGAMONE Search LOSIGAMONE
3 DESGLYCINYL REMACEMIDE 1468059 5% 100% 5 Search DESGLYCINYL+REMACEMIDE Search DESGLYCINYL+REMACEMIDE
4 REMACEMIDE HYDROCHLORIDE 1027634 7% 50% 7 Search REMACEMIDE+HYDROCHLORIDE Search REMACEMIDE+HYDROCHLORIDE
5 FPL 12495AA 880835 3% 100% 3 Search FPL+12495AA Search FPL+12495AA
6 CARABERSAT 391481 2% 67% 2 Search CARABERSAT Search CARABERSAT
7 ANIMAL MODEL OF SEIZURES 293612 1% 100% 1 Search ANIMAL+MODEL+OF+SEIZURES Search ANIMAL+MODEL+OF+SEIZURES
8 AO 242 293612 1% 100% 1 Search AO+242 Search AO+242
9 AO 294 293612 1% 100% 1 Search AO+294 Search AO+294
10 AO 620 293612 1% 100% 1 Search AO+620 Search AO+620

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MALEK, R , BOROWICZ, KK , KIMBER-TROJNAR, Z , SOBIESZEK, G , PISKORSKA, B , CZUCZWAR, SJ , (2003) REMACEMIDE - A NOVEL POTENTIAL ANTIEPILEPTIC DRUG.POLISH JOURNAL OF PHARMACOLOGY. VOL. 55. ISSUE 5. P. 691-698 29 53% 7
2 KINGA, KB , MALEK, R , LUSZCZKI, JJ , RATNARAJ, N , PATSALOS, PN , CZUCZWAR, SJ , (2007) ISOBOLOGRAPHIC ANALYSIS OF INTERACTIONS BETWEEN REMACEMIDE AND CONVENTIONAL ANTIEPILEPTIC DRUGS IN THE MOUSE MODEL OF MAXIMAL ELECTROSHOCK.EPILEPSY & BEHAVIOR. VOL. 11. ISSUE 1. P. 6-12 19 56% 0
3 SILLS, GJ , SANTANGELI, S , FORREST, G , BRODIE, MJ , (2002) INFLUENCE OF CYTOCHROME P450 INDUCTION ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF REMACEMIDE HYDROCHLORIDE.EPILEPSY RESEARCH. VOL. 49. ISSUE 3. P. 247-254 15 65% 4
4 SANTANGELI, S , MCNEILL, C , SILLS, GJ , BRODIE, MJ , (2000) SIMULTANEOUS DETERMINATION OF REMACEMIDE HYDROCHLORIDE AND DESGLYCINYLREMACEMIDE (AR-R12495XX) IN BRAIN TISSUE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 746. ISSUE 2. P. 325-329 10 100% 3
5 ZHOU, J , LIU, Q , LI, YH , ZHANG, ZZ , (2012) CHIRAL HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC ANALYSIS OF ENANTIOMERS OF THREO-LOSIGAMONE.JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. VOL. 35. ISSUE 9. P. 1238-1244 9 64% 0
6 SCHACHTER, SC , TARSY, D , (2000) REMACEMIDE: CURRENT STATUS AND CLINICAL APPLICATIONS.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 9. ISSUE 4. P. 871 -883 22 32% 15
7 LEACH, JP , SILLS, GJ , BUTLER, E , FORREST, G , THOMPSON, GG , BRODIE, MJ , (1997) NEUROCHEMICAL ACTIONS OF THE DESGLYCINYL METABOLITE OF REMACEMIDE HYDROCHLORIDE (ARL 12495AA) IN MOUSE BRAIN.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 121. ISSUE 5. P. 923-926 11 61% 5
8 XIAO, YS , LUO, M , WANG, J , LUO, HY , (2015) LOSIGAMONE ADD-ON THERAPY FOR PARTIAL EPILEPSY.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 12. P. - 9 45% 0
9 PALMER, GC , CREGAN, EF , BIALOBOK, P , SYDSERFF, SG , HUDZIK, TJ , MCCARTHY, DJ , (1999) THE LOW-AFFINITY, USE-DEPENDENT NMDA RECEPTOR ANTAGONIST AR-R 15896AR - AN UPDATE OF PROGRESS IN STROKE.NEUROPROTECTIVE AGENTS: FOURTH INTERNATIONAL CONFERENCE. VOL. 890. ISSUE . P. 406 -420 13 45% 10
10 PALMER, GC , MURRAY, RJ , CRAMER, CL , STAGNITTO, ML , KNOWLES, MK , FREEDMAN, LR , EISMANN, MS , MAHMOOD, N , BALESTRA, M , BORRELLI, AR , ET AL (1999) [S]-AR-R 15896AR - A NOVEL ANTICONVULSANT: ACUTE SAFETY, PHARMACOKINETIC AND PHARMACODYNAMIC PROPERTIES.JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 288. ISSUE 1. P. 121-132 12 48% 7

Classes with closest relation at Level 1


Rank Class id link
1 19745 MEMANTINE//AMANTADINE//UNCOMPETITIVE ANTAGONIST
2 3055 LAMOTRIGINE//FELBAMATE//OXCARBAZEPINE
3 19178 LACOSAMIDE//ESLICARBAZEPINE ACETATE//PERAMPANEL
4 16431 LY 300164//FLUNARIZINE//EXPTL EPILEPSIEFOR
5 12436 ANTICONVULSANT ACTIVITY//EPILEPSY BRANCH//ANTICONVULSANTS
6 37006 GENERATOR SEEDING//IBM COMPATIBLE MICROCOMPUTER//IBM MICROCOMPUTER
7 6033 ARCAINE//POLYAMINES//SPERMINE
8 12755 LEVETIRACETAM//SV2A//BRIVARACETAM
9 9426 PAROXYSMAL DEPOLARIZATION SHIFT//SEIZURE LIKE EVENTS//INTERICTAL BURSTING
10 10889 LUBELUZOLE//NIMODIPINE//LEVEMOPAMIL

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