Class information for:
Level 1: JNK//MKK4//C JUN N TERMINAL KINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5457 1621 48.9 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
204 3       PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE 52492
1195 2             JNK//ERK5//MAP KINASE 9252
5457 1                   JNK//MKK4//C JUN N TERMINAL KINASE 1621

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JNK authKW 617301 18% 11% 290
2 MKK4 authKW 383045 2% 54% 38
3 C JUN N TERMINAL KINASE authKW 347175 7% 16% 118
4 JNK3 authKW 332369 2% 59% 30
5 MKK7 authKW 267530 2% 57% 25
6 JNK2 authKW 230719 1% 58% 21
7 JIP1 authKW 194297 1% 74% 14
8 SP600125 authKW 192643 2% 30% 34
9 JNK1 authKW 177418 2% 30% 31
10 CEP 1347 authKW 159152 1% 65% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 3854 26% 0% 421
2 Biochemistry & Molecular Biology 3785 41% 0% 671
3 Neurosciences 1664 20% 0% 332
4 Oncology 844 14% 0% 221
5 Chemistry, Medicinal 386 5% 0% 86
6 Biophysics 175 5% 0% 79
7 Genetics & Heredity 168 6% 0% 92
8 Developmental Biology 87 2% 0% 30
9 Pharmacology & Pharmacy 50 6% 0% 98
10 Medicine, Research & Experimental 29 3% 0% 46

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVITROGEN DISCOVERY SERV 94178 0% 100% 5
2 BIOL NEURODEG DISORDERS 56507 0% 100% 3
3 MOL THER EUT DRUG DISCOVERY 42379 0% 75% 3
4 NEURONAL DEATH NEUROPROTECT 42379 0% 75% 3
5 CELL CYCLE REGULAT 39967 1% 19% 11
6 BOTNAR UNIT 37671 0% 100% 2
7 INTER METASTASIS GRP 37671 0% 100% 2
8 MOL THER EUT TRANSLAT 37671 0% 100% 2
9 LEAD FINDING DRUG DISPOSIT SAFETY EVALUAT 36216 0% 38% 5
10 PROMOT MED SCI 33896 0% 30% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 3038 10% 0% 161
2 ONCOGENE 2138 3% 0% 46
3 MOLECULAR AND CELLULAR BIOLOGY 1877 3% 0% 48
4 MOLECULAR BRAIN RESEARCH 1637 1% 0% 20
5 JOURNAL OF NEUROCHEMISTRY 1606 3% 0% 43
6 CELL DEATH AND DIFFERENTIATION 983 1% 0% 13
7 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 910 2% 0% 36
8 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION 755 0% 1% 5
9 CELLULAR SIGNALLING 601 1% 0% 12
10 MOLECULAR AND CELLULAR NEUROSCIENCE 531 1% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 JNK 617301 18% 11% 290 Search JNK Search JNK
2 MKK4 383045 2% 54% 38 Search MKK4 Search MKK4
3 C JUN N TERMINAL KINASE 347175 7% 16% 118 Search C+JUN+N+TERMINAL+KINASE Search C+JUN+N+TERMINAL+KINASE
4 JNK3 332369 2% 59% 30 Search JNK3 Search JNK3
5 MKK7 267530 2% 57% 25 Search MKK7 Search MKK7
6 JNK2 230719 1% 58% 21 Search JNK2 Search JNK2
7 JIP1 194297 1% 74% 14 Search JIP1 Search JIP1
8 SP600125 192643 2% 30% 34 Search SP600125 Search SP600125
9 JNK1 177418 2% 30% 31 Search JNK1 Search JNK1
10 CEP 1347 159152 1% 65% 13 Search CEP+1347 Search CEP+1347

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BOGOYEVITCH, MA , NGOEI, KRW , ZHAO, TT , YEAP, YYC , NG, DCH , (2010) C-JUN N-TERMINAL KINASE (JNK) SIGNALING: RECENT ADVANCES AND CHALLENGES.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1804. ISSUE 3. P. 463 -475 98 63% 117
2 COFFEY, ET , (2014) NUCLEAR AND CYTOSOLIC JNK SIGNALLING IN NEURONS.NATURE REVIEWS NEUROSCIENCE. VOL. 15. ISSUE 5. P. 285 -299 97 51% 55
3 BUBICI, C , PAPA, S , (2014) JNK SIGNALLING IN CANCER: IN NEED OF NEW, SMARTER THERAPEUTIC TARGETS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 171. ISSUE 1. P. 24 -37 75 59% 53
4 KOCH, P , GEHRINGER, M , LAUFER, SA , (2015) INHIBITORS OF C-JUN N-TERMINAL KINASES: AN UPDATE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 1. P. 72 -95 87 61% 9
5 HAEUSGEN, W , HERDEGEN, T , WAETZIG, V , (2011) THE BOTTLENECK OF JNK SIGNALING: MOLECULAR AND FUNCTIONAL CHARACTERISTICS OF MKK4 AND MKK7.EUROPEAN JOURNAL OF CELL BIOLOGY. VOL. 90. ISSUE 6-7. P. 536-544 81 70% 46
6 GRACZYK, PP , (2013) JNK INHIBITORS AS ANTI-INFLAMMATORY AND NEUROPROTECTIVE AGENTS.FUTURE MEDICINAL CHEMISTRY. VOL. 5. ISSUE 5. P. 539 -551 75 73% 11
7 DAVIS, RJ , (2000) SIGNAL TRANSDUCTION BY THE JNK GROUP OF MAP KINASES.CELL. VOL. 103. ISSUE 2. P. 239-252 58 44% 2691
8 WANG, X , DESTRUMENT, A , TOURNIER, C , (2007) PHYSIOLOGICAL ROLES OF MKK4 AND MKK7: INSIGHTS FROM ANIMAL MODELS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1773. ISSUE 8. P. 1349-1357 62 78% 63
9 PHILPOTT, KL , FACCI, L , (2008) MAP KINASE PATHWAYS IN NEURONAL CELL DEATH.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 7. ISSUE 1. P. 83-97 89 57% 20
10 ZHENG, K , IQBAL, S , HERNANDEZ, P , PARK, H , LOGRASSO, PV , FENG, YB , (2014) DESIGN AND SYNTHESIS OF HIGHLY POTENT AND ISOFORM SELECTIVE JNK3 INHIBITORS: SAR STUDIES ON AMINOPYRAZOLE DERIVATIVES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 23. P. 10013 -10030 49 88% 2

Classes with closest relation at Level 1


Rank Class id link
1 24101 MIXED LINEAGE KINASE//RPM 1//DLK
2 9419 DUAL SPECIFICITY PHOSPHATASE//MKP 1//MAP KINASE PHOSPHATASE
3 22795 ASK1//PP5//PROTEIN PHOSPHATASE 5
4 5307 MK2//P38 INHIBITORS//P38 ALPHA
5 33806 MODULAR PHARMACOLOGY//RAS RAF ERK1 2//RAS RAF ERK1 2 SIGNALING PATHWAY
6 9970 MAP KINASE KINASE//MAP KINASE//MAP KINASE ACTIVATOR
7 22274 ERK5//MEK5//EXTRACELLULAR SIGNAL REGULATED KINASE 5
8 28520 MAP4K4//TNIK//MST3
9 4454 AP 1//FRA 1//JUN
10 33774 CANC MICROARRAY GENES PROT//SPERM PROTEIN 17//SPAG9

Go to start page